The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor axis as a key player in alveolar bone remodeling.

Celso Martins Queiroz-Junior, Anna Clara Paiva Menezes Santos, Izabela Galvão, Giovanna Ribeiro Souto, Ricardo Alves Mesquita, Marcos Augusto Sá, Anderson José Ferreira

November 2019 Bone

Synopsis of Social media discussions

The discourse reflects casual references to the role of ACE receptors in COVID and hypertension, with comments like questioning the choice of proteins for vaccines, indicating some awareness but limited engagement with the specific research about bone remodeling. This tone and focus demonstrate a general curiosity but not deeply invested or impactful discussions.

A
Agreement
 Neither agree nor disagree

The discussions show mixed opinions, with some skepticism about the research focus and its broader implications.

I
Interest
 Moderate level of interest

There is some curiosity about the topic, especially regarding the biological mechanisms and potential health applications, but overall interest remains moderate.

E
Engagement
 Neutral engagement

Most comments are brief and somewhat superficial, with limited in-depth analysis or detailed discussion of the research findings.

I
Impact
 Neutral impact

The discussions do not suggest significant influence or transformative potential, mostly touching on related yet somewhat tangential themes such as COVID and hypertension.

Social Mentions

YouTube

1 Videos

Twitter

2 Posts

News

1 Articles

Metrics

Video Views

174

Extended Reach

6,525

Social Features

4

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

ACE2-Angiotensin-(1-7)-Mas Receptor Axis in Bone Remodeling

ACE2-Angiotensin-(1-7)-Mas Receptor Axis in Bone Remodeling

This video explores how the ACE2-Ang17-MasR axis influences alveolar bone remodeling. The study demonstrates that activating this pathway promotes bone formation and reduces inflammation, with implications for periodontal disease management.

Queiroz Junior

August 23, 2020

174 views

  • Dr. Yasir Tashkandi
    @yasnota (Twitter)

    @ISICEM @bhwords The covid spike protein binds to ACE receptors. The ACE/Ang II/AT1 axis play a role in the progression of hypertension and is involved in thrombogenic processes. Did they choose the wrong protein as a taget for vaccines?!! https://t.co/omv4spimu9
    view full post

    April 22, 2021

  • Trevor Sutcliffe
    @TrevorSutcliffe (Twitter)

    RT @TrevorSutcliffe: Update on the Angiotensin Converting Enzyme 2-Angiotensin (1–7)-Mas Receptor Axis: Fetal Programing, Sex Differences,…
    view full post

    March 30, 2020

    1

  • Electrically Conductive Biopolymer | PDF | Cardiac Muscle | Tissue ...

    Human bone marrow-derived mesenchymal cessing with tunable fiber diameters [324]. ... 75 (2020) 2169–2188, https://doi.org/10.1016/j.jacc.2020.03.024.
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Abstract Synopsis

  • The study explores how the ACE2-Ang17-MasR axis, part of the renin-angiotensin system, influences bone remodeling, particularly in alveolar bone, and finds that activating this axis promotes bone formation and reduces inflammation in bone cells.
  • Researchers detected ACE2 and MasR proteins in bone cells both in lab cultures and in rat models, showing that stimulating these receptors enhances osteoblast activity (bone formation) and decreases osteoclast differentiation (bone resorption), especially under inflammatory conditions.
  • The findings also highlight that in human gum tissue, ACE2 and MasR are present, and their levels decrease during periodontal disease, suggesting this pathway could be targeted to help manage inflammatory bone loss in conditions like periodontitis.]