Multigenerational epigenetic inheritance: One step forward, two generations back.

Jennifer J Tuscher, Jeremy J Day

December 2019 Neurobiol Dis

Synopsis of Social media discussions

The discussions reflect a nuanced perspective, with some posts highlighting the importance of epigenetic modifications in the brain and potential inheritance of traits like metabolism, using words like 'critical' and 'important,' showing curiosity. Others remain cautious, emphasizing the need for further research, indicated by phrases like 'cautious review,' which signals interest but also skepticism about the current evidence.

A
Agreement
 Neither agree nor disagree

The discussions show mixed reactions; some see the research as promising, while others remain cautious or skeptical about its significance.

I
Interest
 Moderate level of interest

Most posts demonstrate curiosity about the topic, with some mentioning its relevance to brain development and disease but few deeply exploring implications.

E
Engagement
 Moderate level of engagement

Posts include references to cellular mechanisms and broader implications, indicating a moderate level of engagement with the science, but lack extensive debate or critique.

I
Impact
 Neutral impact

While the topic could influence ongoing research, the overall tone suggests an acknowledgment of potential rather than definitive impact, reflecting cautious interest.

Social Mentions

YouTube

2 Videos

Facebook

2 Posts

Twitter

7 Posts

News

2 Articles

Metrics

Video Views

44

Total Likes

8

Extended Reach

37,167

Social Features

13

Timeline: Posts about article

Top Social Media Posts

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  • Teresa Hartman
    @thartman2u (Twitter)

    RT @pfanderson: Multigenerational #epigenetic inheritance: One step forward, two generations back. https://t.co/zAQZF0lisF #igtt #epigeneti…
    view full post

    November 2, 2019

    1

  • PF Anderson @pfanderson@disabled.social
    @pfanderson (Twitter)

    Multigenerational #epigenetic inheritance: One step forward, two generations back. https://t.co/zAQZF0lisF #igtt #epigenetics
    view full post

    November 1, 2019

    1

    1

  • Agustín Fuentes
    @Anthrofuentes (Twitter)

    RT @EES_update: Cautious review of multigenerational epigenetic mechanisms in the central nervous system: "Multigenerational epigenetic inh…
    view full post

    September 6, 2019

    1

  • EES Update
    @EES_update (Twitter)

    Cautious review of multigenerational epigenetic mechanisms in the central nervous system: "Multigenerational epigenetic inheritance: One step forward, two generations back" by Tuscher and Day in Neurobiology of Disease https://t.co/oJJ8liZAKE #openaccess h/t @GillianRBrown1
    view full post

    September 6, 2019

    5

    1

  • Epigenetics News
    @Epigenetics (Twitter)

    Multigenerational epigenetic inheritance One step forward two generations back.: Modifications to DNA and histone proteins serve a critical regulatory role in the developing and adult brain and over a decade of research has established the importance of… https://t.co/1uimyLOLJc
    view full post

    August 31, 2019

    2

  • NeuroGenetics papers
    @NeuroGen_papers (Twitter)

    PubMed: Multigenerational epigenetic inheritance: One step forward, two generations back. https://t.co/JsUG19ybFh
    view full post

    August 31, 2019

  • Epigenética
    @Epigenetica (Twitter)

    New in Pubmed: "Multigenerational epigenetic inheritance: One step forward, two generations back." https://t.co/2JM9aTutUx
    view full post

    August 31, 2019

Abstract Synopsis

  • This text explores how epigenetic modifications, which regulate gene expression in the brain, might be inherited across multiple generations, potentially influencing development, behavior, and disease, though the mechanisms and validity of such inheritance are still debated.
  • It discusses the cellular processes involved in transferring epigenetic information, including what happens in germline and somatic cells, and how ancestral experiences might affect traits like metabolism in descendants.
  • The review also highlights the current challenges and limitations in studying multigenerational epigenetic inheritance, emphasizing the need for cautious interpretation of the existing research.]