Neuroendocrinology May 2021 PMID 31484186

Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa.

Vincent Florent, Marc Baroncini, Patrice Jissendi-Tchofo, Renaud Lopes, Matthieu Vanhoutte, Sowmyalakshmi Rasika, Jean-Pierre Pruvo, Jean Vignau, Stephane Verdun, Jeanette E Johansen, Marie Pigeyre, Sebastien G Bouret, Ida A K Nilsson, Vincent Prevot

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Peak: 2 in Oct 2020

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The discussions show a mild interest in the research, with phrases like 'Read a new research article' and hashtags highlighting the focus on endocrinology and appetite regulation, indicating curiosity and appreciation for scientific insights. The tone is straightforward and promotional, emphasizing the importance of the study but without deep engagement or critique.

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Abstract in brief

The study finds that individuals with anorexia nervosa (AN) show an unusual brain response to feeding, specifically a drop in hypothalamic glutamate/glutamine levels, unlike healthy, lean people.
These changes are linked to structural differences in parts of the hypothalamus, such as decreased neural wiring in the arcuate nucleus and increased connectivity in the lateral hypothalamic area, which play roles in regulating food intake and energy.
Understanding these specific brain imbalances could lead to new ways to diagnose and treat AN and other conditions involving abnormal body weight and energy regulation.]

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All mentions

Examining GABA Receptor Mutations in Anorexia Nervosa Risk

This video discusses GABA receptor mutations as a potential contributor to anorexia nervosa. It references substantial research linking elevated GABAA receptor levels to activity-based anorexia in adolescent female…

Jessica Bodie · Oct 11, 2020 59 views

Understanding Gamma Aminobutyric Acid in Anorexia Nervosa

A meta-analysis of 36 studies investigated mortality rates associated with anorexia nervosa (AN). The findings reveal significantly higher mortality rates in AN compared to bulimia nervosa and other eating disorders…

Jessica Bodie · Oct 31, 2020 30 views

Endocrinology | Karger

@EndoKarger · X

Read a new research article on "Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa” for free at https://t.co/0VfPWHe7G9 #Endocrinology #Appetite https://t.co/zOJrqSRxTH

Apr 30, 2020 · 2 likes · 2,481 followers View post →