November 2019 PMID 31611705

Advancing functional connectivity research from association to causation.

Andrew T Reid, Drew B Headley, Ravi D Mill, Ruben Sanchez-Romero, Lucina Q Uddin, Daniele Marinazzo, Daniel J Lurie, Pedro A Valdés-Sosa, Stephen José Hanson, Bharat B Biswal, Vince Calhoun, Russell A Poldrack, Michael W Cole

Mentions

117
Peak: 90 in Oct 2019
across 5 sources since Oct 2019

Extended reach

866,380
potential audience

Total likes

114

Video views

954

Mentions per month

Oct 2019 – Sep 2025

Where it's discussed

  • X / Twitter101 posts
  • Facebook9 posts
  • Bluesky3 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions reveal a strong engagement with the research, featuring users discussing their previous work, such as references to co-authored papers like Reid et al. (2019), and the excitement surrounding breakthroughs in functional connectivity research. The use of phrases like 'achievement unlocked' and calls to 'check it out' create a tone of enthusiasm and urgency, emphasizing the importance of the findings and their potential impact on the neuroscience community.

AgreementModerate agreement

Overall, there is a moderate level of agreement with the ideas put forward in the publication, with many posts referencing it positively.

InterestHigh interest

There is a significant level of interest in the concepts discussed, as evidenced by users expressing excitement to read and learn more about the publication.

EngagementModerate engagement

The discussions show some depth, with individuals sharing supplementary material and engaging in related topics, though not all posts exhibit profound analysis.

ImpactHigh impact

Many participants perceive the publication as having a high impact on the field of neuroscience, indicating it may influence future research directions.

Abstract in brief

  • The study emphasizes that understanding brain functions requires moving from just looking at associations between brain areas (functional connectivity) to identifying actual causal interactions.
  • It highlights that while traditional methods like correlation and coherence are commonly used, they have limitations in establishing causation.
  • The authors propose refining current functional connectivity methods by incorporating best practices and suggesting alternative measures to enhance the accuracy of causal inferences in brain research.

Top posts

Most liked on X and Bluesky
Nature Neuroscience
@NatureNeuro · X

A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://t.co/b9bJfbbhJG

Oct 18, 2019 · 73 likes · 32 shares · 554,302 followers View post →
Danielle DeSouza
@NeuroDanielle · X

Excited to read this one! Advancing functional connectivity research from association to causation. https://t.co/qBW6oIvpBF

Oct 14, 2019 · 5 likes · 1,564 followers View post →
Nayef Al-Rodhan
@SustainHistory · X

Advancing functional connectivity research from association to causation Cognition and behavior emerge from brain network interactions, such that investigating causal interactions should be central to the study of brain function. https://t.co/dOFbVMhKJa

Oct 16, 2019 · 4 likes · 2 shares · 53,375 followers View post →
Vince Calhoun @vcalhoun.bsky.social
@vdcalhoun · X

@KordingLab Why do you think folks hate it? Maybe they just hate tweet shaming. ;-) FYI, a couple relevant pubs here on learning from undersampled data and causal modeling of FC: https://t.co/kNWPTzGvct https://t.co/qA0Ocs1Spk

Oct 21, 2021 · 4 likes · 5,499 followers View post →
Lucina Uddin
@LucinaUddin · X

@NicoleCRust https://t.co/PoPjQAZn6j

May 12, 2022 · 3 likes · 13,870 followers View post →
@parkvillegeek
@ParkvilleGeek · X

Advancing functional connectivity research from association to causation. - PubMed - NCBI https://t.co/Gro84HrJvs https://t.co/HxFstSfNNI

Oct 30, 2019 · 3 likes · 2,679 followers View post →

All mentions

Michael W. Cole
@mwcole.bsky.social · Bluesky

I think both of those explanations are plausible. I co-authored a paper on functional/effective connectivity in 2019 that may be helpful: Reid et al. (2019). "Advancing functional connectivity research from association to causation". Nature Neuroscience. www.colelab.org/pubs/Reid201...

Sep 16, 2025 · 1 like · 1 share View post →
Daniele Marinazzo
@danielemarinazzo.bsky.social · Bluesky

you know it well pubmed.ncbi.nlm.nih.gov/31611705/

Feb 13, 2025 · 3 likes · 1 share View post →
Daniele Marinazzo
@danielemarinazzo.bsky.social · Bluesky

Achievement unlocked: made it to the super-inspiring @puntofisso.bsky.social 's data newsletter! buttondown.email/puntofisso/a... How did we go from D-K to our two papers? pubmed.ncbi.nlm.nih.gov/31611705/ www.nature.com/articles/s41... ? Answer in the next post

Dec 20, 2023 · 1 share View post →
Lucina Uddin
@LucinaUddin · X

@NicoleCRust https://t.co/PoPjQAZn6j

May 12, 2022 · 3 likes · 13,870 followers View post →
Michael W. Cole
@TheColeLab · X

@KordingLab @PessoaBrain @northernthrux @aina_puce @johndmurray We have systematically listed our assumptions behind FC measures in Reid et al. 2019: https://t.co/gfNSJypmge More detailed in the supplemental materials: https://t.co/088zBv2W7a

Feb 14, 2022 · 1 like · 3,515 followers View post →
Michael W. Cole
@TheColeLab · X

@AFNIman @knutson_brain @KordingLab @PessoaBrain @northernthrux @aina_puce @johndmurray IMHO, I think that’d be throwing the baby out with the bath water. Here’s one of our attempts to not throw out the “functional connectivity baby”, heheh: “Advancing functional connectivity research from association to causation” https://t.co/gfNSJypmge

Feb 14, 2022 · 3,515 followers View post →
Vince Calhoun @vcalhoun.bsky.social
@vdcalhoun · X

@KordingLab Why do you think folks hate it? Maybe they just hate tweet shaming. ;-) FYI, a couple relevant pubs here on learning from undersampled data and causal modeling of FC: https://t.co/kNWPTzGvct https://t.co/qA0Ocs1Spk

Oct 21, 2021 · 4 likes · 5,499 followers View post →
Andy Xor
@andy_xor · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Aug 12, 2021 · 109 shares · 1,442 followers View post →
Cuba Ciencia
@cubaciencia · X

PubMed: https://t.co/Qm9rhy2NlL Advancing functional connectivity research from association to causation. Related Articles Advancing functional connectivity research from association to causation. Nat Neurosci. 2019 11;22(11):1751-1760 Authors: Reid AT, Headley DB, Mill RD,…

Feb 1, 2020 · 1,340 followers View post →
David V. Smith (@dvsmith.bsky.social)
@DVSneuro · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Nov 16, 2019 · 109 shares · 1,540 followers View post →
Syed Ali Raza (Ali)
@Ali_SyedRaza · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Nov 16, 2019 · 109 shares · 2,950 followers View post →
Yuehua Xu
@YuehuaXu_bnu · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Nov 16, 2019 · 109 shares · 187 followers View post →
Juando Gispert
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Carrisa V Cocuzza, PhD (she/her)
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RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Nov 5, 2019 · 109 shares · 352 followers View post →
@parkvillegeek
@ParkvilleGeek · X

Advancing functional connectivity research from association to causation. - PubMed - NCBI https://t.co/Gro84HrJvs https://t.co/HxFstSfNNI

Oct 30, 2019 · 3 likes · 2,679 followers View post →
Brian P. Keane @briankeanelab.bsky.social
@BrianKeaneLab · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 29, 2019 · 109 shares · 108 followers View post →
Morgan Hough (mhough.bsky.social)
@mhough · X

RT @LucinaUddin: Check it out: "Advancing functional connectivity research from association to causation". https://t.co/6w5w3kY1Vp

Oct 24, 2019 · 5 shares · 765 followers View post →
Nayef Al-Rodhan
@SustainHistory · X

RT @SustainHistory: Advancing functional connectivity research from association to causation Cognition and behavior emerge from brain netw…

Oct 22, 2019 · 2 shares · 53,375 followers View post →
Alessandro Principe
@DR4Q · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 21, 2019 · 32 shares · 39 followers View post →
michael sirbola
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Oct 20, 2019 · 109 shares · 391 followers View post →
Meghan Boggs
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 8 followers View post →
Zakaria Djebbara
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 720 followers View post →
UNF - Montreal
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 188 followers View post →
r.patrick.xian
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 218 followers View post →
jjsutachan
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 217 followers View post →
Sebastian Holst
@CamilloHolst · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 96 followers View post →
Sharlene Newman
@S_D_Newman · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 1,371 followers View post →
Jaqueline Nava-Gómez ♪
@Jaquelinesdi25 · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 19, 2019 · 32 shares · 888 followers View post →
Wei Cheng
@WeiFDU · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 433 followers View post →
Jibran Khokhar
@DrJKhokhar · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 10,775 followers View post →
Keri Martinowich
@martinowk · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 2,946 followers View post →
Jane Tan
@JaneTan_HL · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 64 followers View post →
Daifeng Wang
@daifengwang · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 360 followers View post →
Jessica Chung
@dra_jessica · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 7,477 followers View post →
Ram Fernando
@RamFernando1 · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 905 followers View post →
Marcus Daghlian
@DagNsci · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 165 followers View post →
Coka Kejia Hu
@Coka_Hoo · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

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Towfique Raj
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

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CLaE
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

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@DVSneuro · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 1,540 followers View post →
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@DrCanB · X

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Oct 18, 2019 · 32 shares · 446 followers View post →
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Oct 18, 2019 · 32 shares · 645 followers View post →
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@MossResearch · X

RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 1,157 followers View post →
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

Oct 18, 2019 · 32 shares · 293 followers View post →
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RT @NatureNeuro: A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://…

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Nature Neuroscience
@NatureNeuro · X

A Perspective on advancing functional connectivity research from association to causation https://t.co/0SD1jnx4dR https://t.co/b9bJfbbhJG

Oct 18, 2019 · 73 likes · 32 shares · 554,302 followers View post →
Anthony Gifuni
@gifuni · X

RT @LucinaUddin: Check it out: "Advancing functional connectivity research from association to causation". https://t.co/6w5w3kY1Vp

Oct 17, 2019 · 5 shares · 201 followers View post →
Ignacio Obeso
@ignacio_obeso · X

Advancing functional connectivity research from association to causation | Nature Neuroscience https://t.co/RbuqGnQz1J

Oct 17, 2019 · 1 like · 338 followers View post →
Boris Kleber
@Boris_Kleber · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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James Booth
@DrJamesBooth · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 16, 2019 · 109 shares · 6,376 followers View post →
Cuba Ciencia
@cubaciencia · X

PubMed: https://t.co/Qm9rhy2NlL Advancing functional connectivity research from association to causation. Related Articles Advancing functional connectivity research from association to causation. Nat Neurosci. 2019 Oct 14;: Authors: Reid AT, Headley DB, Mill RD, Sanchez-Ro…

Oct 16, 2019 · 1,340 followers View post →
Nayef Al-Rodhan
@SustainHistory · X

Advancing functional connectivity research from association to causation Cognition and behavior emerge from brain network interactions, such that investigating causal interactions should be central to the study of brain function. https://t.co/dOFbVMhKJa

Oct 16, 2019 · 4 likes · 2 shares · 53,375 followers View post →
Sandra Palma M
@SandraPalmaM · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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@ASlachevsky · X

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Oct 15, 2019 · 109 shares · 5,418 followers View post →
Community Health & Aging Outcomes Lab
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Oct 15, 2019 · 109 shares · 136 followers View post →
Kaz_Uehara
@kazu19_brain · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 441 followers View post →
Michael Fox
@foxmdphd · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 6,679 followers View post →
Fei He
@FeiHeUK · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 206 followers View post →
Marco Pagani
@MarcoPagani1985 · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 795 followers View post →
Michael Ewers
@MichaelEwers12 · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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@MarcoLinSight · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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Jia-Hou Poh
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RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 311 followers View post →
Yuan Chang Leong
@YuanChangLeong · X

RT @LucinaUddin: Check it out: "Advancing functional connectivity research from association to causation". https://t.co/6w5w3kY1Vp

Oct 15, 2019 · 5 shares · 1,027 followers View post →
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@KousiksarathyS · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 308 followers View post →
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@FPFischmeister · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 492 followers View post →
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RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 561 followers View post →
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RT @LucinaUddin: Check it out: "Advancing functional connectivity research from association to causation". https://t.co/6w5w3kY1Vp

Oct 15, 2019 · 5 shares · 2,287 followers View post →
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@NeilGerardo · X

Advancing functional connectivity research from association to causation https://t.co/A0EBlubmMf

Oct 15, 2019 · 791 followers View post →
Randy Ellis
@randalljellis · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 15, 2019 · 109 shares · 1,084 followers View post →
Roma Siugzdaite
@RSiugzdaite · X

Advancing functional connectivity research from association to causation!!! https://t.co/5yJkVeR6a5

Oct 15, 2019 · 1 like · 885 followers View post →
Sarah Louise Blankenship
@sl_blankenship · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

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Rocinante
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Oct 15, 2019 · 109 shares · 320 followers View post →
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RT @LucinaUddin: Check it out: "Advancing functional connectivity research from association to causation". https://t.co/6w5w3kY1Vp

Oct 15, 2019 · 5 shares · 217 followers View post →
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Oct 15, 2019 · 109 shares · 1,069 followers View post →
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Mathilda Froesel
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RT @CogSciSoc: Advancing functional connectivity research from association to causation https://t.co/K7ZyriKLHY v/ @NatureNews https://t.co…

Oct 15, 2019 · 1 share · 175 followers View post →
Gerold Baier
@GeroldBaier · X

Advancing functional connectivity research from association to causation https://t.co/DJk6s3wsUW

Oct 15, 2019 · 1 like · 565 followers View post →
Joan Duprez
@J_Duprez · X

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Alexandra Badea
@portokalh · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 14, 2019 · 109 shares · 955 followers View post →
Danielle DeSouza
@NeuroDanielle · X

Excited to read this one! Advancing functional connectivity research from association to causation. https://t.co/qBW6oIvpBF

Oct 14, 2019 · 5 likes · 1,564 followers View post →
Lauren D. Hill-Bowen
@laurend_bowen · X

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Hans-Christoph Nuerk
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Kevin Anderson
@KevinMAnder · X

RT @TheColeLab: Just out at Nature Neuroscience, our multi-lab collaboration, "Advancing functional connectivity research from association…

Oct 14, 2019 · 109 shares · 429 followers View post →