Bone Res August 2019 PMID 31666997

Ankylosing spondylitis: etiology, pathogenesis, and treatments.

Wei Zhu, Xuxia He, Kaiyuan Cheng, Linjie Zhang, Di Chen, Xiao Wang, Guixing Qiu, Xu Cao, Xisheng Weng

Mentions

6
Peak: 1 in Sep 2020
across 3 sources since Sep 2020

Extended reach

4,565
potential audience

Total likes

27

Video views

3,867

Mentions per month

Sep 2020 – Jun 2025

Where it's discussed

  • YouTube3 videos
  • News2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

Discussions reveal a shared recognition of the importance of immune pathways such as IL-23/17 and genetic factors like HLA-B27, with phrases like 'important advances' and 'new hope for treatments' illustrating the general interest. However, the tone remains somewhat surface-level, with remarks like 'interesting read' and 'worth knowing,' indicating moderate engagement without deep critical analysis.

AgreementModerate agreement

Most discussions acknowledge the relevance of the publication, with some expressing support for the emphasis on immune pathways and genetic factors.

InterestModerate interest

Participants show moderate interest, touching on aspects like new treatments and the immune mechanisms but without deep enthusiasm.

EngagementModerate engagement

Comments reflect basic engagement, often mentioning the content of the publication but lacking detailed analysis or critique.

ImpactNeutral impact

The discussions suggest a limited perceived immediate impact, focusing more on understanding rather than transformative change.

Abstract in brief

  • Ankylosing spondylitis (AS) is a chronic autoimmune disease primarily affecting the spine, leading to pain and, in advanced cases, spine fusion.
  • Recent research highlights the vital roles of immune cells, cytokines, particularly the IL-23/17 axis, and genetic factors like the HLA-B27 gene in the disease’s development, though its exact cause remains unclear.
  • Treatment options include medications and surgery, with ongoing research exploring new therapies based on understanding the disease's genetic and cytokine pathways.]

Top posts

Most liked on X and Bluesky
Carolina Manzur
@CarolinaManzurB · X

https://t.co/pCCCVZJEkJ #rotreuma @anammejia_ @carvicab

Sep 9, 2020 · 3 likes · 699 followers View post →

All mentions

Carolina Manzur
@CarolinaManzurB · X

https://t.co/pCCCVZJEkJ #rotreuma @anammejia_ @carvicab

Sep 9, 2020 · 3 likes · 699 followers View post →