January 2020 PMID 31758375

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells.

Jahnnyer Martínez-Moreno, Juan C Hernandez, Silvio Urcuqui-Inchima

Mentions

14
Peak: 4 in May 2020
across 4 sources since Nov 2019

Extended reach

14,370
potential audience

Total likes

22

Video views

203

Mentions per month

Nov 2019 – Nov 2020

Where it's discussed

  • X / Twitter7 posts
  • Facebook3 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The groups' comments reflect a moderate level of engagement, with mentions of how high doses of vitamin D may influence dengue virus replication and immune responses, such as cytokine changes. The tone remains fairly neutral and informational, focusing on what the study examines rather than advocating for policy change or expressing strong opinions, which explains the neutral impact and interest scores.

AgreementNeither agree nor disagree

The discussions are mostly neutral or mildly supportive, with no strong disagreement expressed about the study.

InterestModerate interest

Participants show some curiosity, especially regarding the potential health implications of vitamin D in dengue, but not overwhelming enthusiasm.

EngagementModerate engagement

There is moderate engagement, with users referencing the core aspects of the study like immune responses and cytokine modulation, indicating a basic level of thoughtful discussion.

ImpactNeutral impact

The overall influence appears limited, as the comments suggest interest but do not demonstrate widespread acknowledgment of major implications or calls for action.

Abstract in brief

  • The study investigates how high doses of vitamin D supplementation influence dengue virus (DENV) infection and immune responses in dendritic cells, finding that 4000 IU/day of vitamin D reduces DENV infection and modulates immune markers.
  • Specifically, higher vitamin D intake decreases susceptibility of dendritic cells to DENV2, reduces the expression of toll-like receptors (TLRs), lowers pro-inflammatory cytokines (IL-12, IL-8), and increases anti-inflammatory cytokine (IL-10).
  • These results suggest that vitamin D could potentially enhance innate immunity against DENV infection, but further research is needed to fully understand its role in viral replication and immune regulation.]

Top posts

Most liked on X and Bluesky
Dendritic cells
@DCell_papers · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells. https://t.co/RMzwx2yvu0

Nov 24, 2019 · 2 likes · 1 share · 700 followers View post →
Juan K Hernandez
@KJuankhernandez · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells | SpringerLink https://t.co/PRzL8SSpj7

May 20, 2020 · 2 likes · 1 share · 70 followers View post →
EurekaMag
@EurekaMag · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells https://t.co/yrDn3an4dL

Nov 18, 2020 · 2 shares · 6,519 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine p…

Nov 18, 2020 · 2 shares · 5,257 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine p…

Nov 18, 2020 · 2 shares · 1,241 followers View post →
Andres F Vallejo
@afvallejop · X

RT @DCell_papers: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokin…

Nov 25, 2019 · 1 share · 330 followers View post →

All mentions

POPLINE
@POPLINE_org · X

RT @EurekaMag: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine p…

Nov 18, 2020 · 2 shares · 5,257 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine p…

Nov 18, 2020 · 2 shares · 1,241 followers View post →
EurekaMag
@EurekaMag · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells https://t.co/yrDn3an4dL

Nov 18, 2020 · 2 shares · 6,519 followers View post →
jorgedo12
@jorgedo121 · X

RT @KJuankhernandez: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cyto…

May 21, 2020 · 1 share · 31 followers View post →
Juan K Hernandez
@KJuankhernandez · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells | SpringerLink https://t.co/PRzL8SSpj7

May 20, 2020 · 2 likes · 1 share · 70 followers View post →
Andres F Vallejo
@afvallejop · X

RT @DCell_papers: Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokin…

Nov 25, 2019 · 1 share · 330 followers View post →
Dendritic cells
@DCell_papers · X

Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells. https://t.co/RMzwx2yvu0

Nov 24, 2019 · 2 likes · 1 share · 700 followers View post →