January 2020 PMID 31789517

Asymmetric Total Synthesis of Pre-schisanartanin C.

Yan-Long Jiang, Hai-Xin Yu, Yong Li, Pei Qu, Yi-Xin Han, Jia-Hua Chen, Zhen Yang

Mentions

18
Peak: 6 in Dec 2019
across 3 sources since Dec 2019

Extended reach

565,190
potential audience

Total likes

194

Video views

13,835

Mentions per month

Dec 2019 – May 2023

Where it's discussed

  • X / Twitter14 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions reveal a positive attitude toward the article, with posts mentioning techniques like cyclopropanation and Stille coupling, and expressing admiration for the researchers’ achievements, which underscores their high interest and recognition of the study's scientific importance.

AgreementModerate agreement

Most discussions express appreciation and admiration for the complexities of the synthesis, indicating general agreement with the significance of the work.

InterestHigh interest

The majority of posts show high curiosity, referencing specific methods and expressing fascination, reflecting strong interest.

EngagementModerate engagement

Many discussions detail the synthesis steps and acknowledge personal familiarity or previous work, showing moderate to deep engagement.

ImpactModerate impact

Some posts highlight the innovative techniques and the potential influence on future research, suggesting moderate impact.

Abstract in brief

  • The paper details the enantioselective total synthesis of Preschisanartanin C, a potent nortriterpenoid with antihepatitis, antitumor, and anti-HIV properties, using advanced organic chemistry techniques.
  • It highlights key steps such as a gold-catalyzed intramolecular cyclopropanation to create a bicyclo[6.10]nonane core and a sequence of reactions including Pd-catalyzed Stille coupling, Sharpless asymmetric dihydroxylation, and lactonization to construct the molecule's side chain.
  • The methods developed not only enable synthesis of Preschisanartanin C but also open pathways for creating other related compounds with similar rigid bicyclic cores.]

Top posts

Most liked on X and Bluesky
Phil Knutson, PhD ⌬
@Phil_Knutson · X

Long ago, as an REU student, I worked on these molecules and they were HARD. The project was ultimately abandoned but this group was able to make a member of the family! Really impressed! They even used a cycloisomerization! #chemtwitter https://t.co/LaLnGFqwTN

Jan 14, 2020 · 20 likes · 1 share · 5,112 followers View post →
ヒイラギ@読書&英語
@hieragey · X

Pre-schisanartanin Cの全合成 超大作ですね ぜひ合成研の論文紹介に Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/7gs55mHF3O

Dec 18, 2019 · 14 likes · 1 share · 2,147 followers View post →
Prof. MLN Rao
@MlnProf · X

#Chemlearning #Organicsynthesis #Totalsynthesis An interesting.... Asymmetric Total Synthesis of Pre-schisanartanin C ...#cyclopropanation ...#asymmetric #Diels–Alder ...#Pd-catalyzed #Stille coupling ...#Sharpless #dihydroxylation ...#lactonization https://t.co/qTxLonSB5H

May 18, 2023 · 11 likes · 2 shares · 383 followers View post →
有機化学を学ぶ人
@yuukiwomanabu · X

Peking大Zhen Yang先生。お家芸感ある骨格の化合物の全合成ですね。 #学ぶの論文紹介 Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/WW2ClJ8hBF

Feb 4, 2020 · 3 likes · 1 share · 6,516 followers View post →
Chemistry News
@ChemistryNews · X

Just Published: Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/1yxYFSliKn

Dec 17, 2019 · 2 likes · 517,867 followers View post →
EurekaMag
@EurekaMag · X

Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/UTu0LiSd4X

Jul 25, 2020 · 2 shares · 6,475 followers View post →

All mentions

Fen
@Fenrir188 · X

RT @MlnProf: #Chemlearning #Organicsynthesis #Totalsynthesis An interesting.... Asymmetric Total Synthesis of Pre-schisanartanin C ...#c…

May 19, 2023 · 2 shares · 17 followers View post →
Prof. MLN Rao
@MlnProf · X

#Chemlearning #Organicsynthesis #Totalsynthesis An interesting.... Asymmetric Total Synthesis of Pre-schisanartanin C ...#cyclopropanation ...#asymmetric #Diels–Alder ...#Pd-catalyzed #Stille coupling ...#Sharpless #dihydroxylation ...#lactonization https://t.co/qTxLonSB5H

May 18, 2023 · 11 likes · 2 shares · 383 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/UTu0LiSd4X

Jul 25, 2020 · 2 shares · 1,240 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/UTu0LiSd4X

Jul 25, 2020 · 2 shares · 5,268 followers View post →
EurekaMag
@EurekaMag · X

Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/UTu0LiSd4X

Jul 25, 2020 · 2 shares · 6,475 followers View post →
有機化学を学ぶ人
@yuukiwomanabu · X

Peking大Zhen Yang先生。お家芸感ある骨格の化合物の全合成ですね。 #学ぶの論文紹介 Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/WW2ClJ8hBF

Feb 4, 2020 · 3 likes · 1 share · 6,516 followers View post →
Raphael
@raphaelkylej · X

RT @Phil_Knutson_: Long ago, as an REU student, I worked on these molecules and they were HARD. The project was ultimately abandoned but th…

Jan 14, 2020 · 1 share · 4,756 followers View post →
Phil Knutson, PhD ⌬
@Phil_Knutson · X

Long ago, as an REU student, I worked on these molecules and they were HARD. The project was ultimately abandoned but this group was able to make a member of the family! Really impressed! They even used a cycloisomerization! #chemtwitter https://t.co/LaLnGFqwTN

Jan 14, 2020 · 20 likes · 1 share · 5,112 followers View post →
Yang Feng
@yang_feng_chem · X

Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/92gB1hZnhu

Dec 30, 2019 · 42 followers View post →
Yang Feng
@yang_feng_chem · X

Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/418Nz7MLZS

Dec 19, 2019 · 42 followers View post →
Cと呼ばれる大学生@化学垢
@chemistryofc · X

RT @OrgChemRarikuma: Pre-schisanartanin Cの全合成 超大作ですね ぜひ合成研の論文紹介に Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/7gs55mHF3O

Dec 18, 2019 · 1 share · 1,417 followers View post →
ヒイラギ@読書&英語
@hieragey · X

Pre-schisanartanin Cの全合成 超大作ですね ぜひ合成研の論文紹介に Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/7gs55mHF3O

Dec 18, 2019 · 14 likes · 1 share · 2,147 followers View post →
Chemistry News
@ChemistryNews · X

Just Published: Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/1yxYFSliKn

Dec 17, 2019 · 2 likes · 517,867 followers View post →
Yuefan Wang
@wangyuefan · X

PhD group work. Familiar with every step... Asymmetric Total Synthesis of Pre-schisanartanin C https://t.co/7Alzo2uj2J

Dec 13, 2019 · 44 followers View post →