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Several discussions emphasize the significance of the findings about trypsin's ability to facilitate zoonotic bat coronaviruses' infections, with phrases like 'unlocked species barrier' and references to Ralph Baric’s earlier research. The tone ranges from analytical to conspiratorial, where some users question the implications of the methods used, displaying a mixture of respect for the research's scientific value with an underlying critique of its potential misuse or misinterpretation.
Many discussions reflect support for the article's insights on trypsin's role in overcoming infection barriers, showing moderate consensus among participants.
Participants demonstrate a high level of curiosity toward the implications of trypsin treatment, as evidenced by their references to related studies and ongoing debates around zoonotic viruses.
Numerous posts delve into the specifics of the research, including technical aspects and related studies, indicating a deep engagement with the topic.
There is a strong perception that this research could significantly affect future studies and strategies surrounding zoonotic infections.
Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to grow in the lab. But this also helps to prevent furin cleavage sites from being selected against. https://t.co/ykXK9258eS
Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting bat cells w/ HIV in 2018 https://t.co/sBNVwS87Qa Infecting live bats dreaming of FCS https://t.co/ZGqCZNDmf2 RXXR in 2019 https://t.co/v0EeyHazMp
Designing vaccines eliciting broad merbecovirus immunity is going to be challenging as MERS-CoV & PDF-2180 share only 49% and 34% amino acid sequence identity in their S1 subunit and receptor-binding domains, respectively 17/18 https://t.co/sSQcybzmLP
15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future coronavirus emergence events in humans" Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection (2019) https://t.co/igsmAKqgME https://t.co/CC2CmyLhZH
7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (~same thing as SARS2) https://t.co/v0EeyHazMp
However, the NeoCoV and PDF-2180 spikes are highly divergent to the MERS-CoV spike in the receptor-binding S1 subunit, explaining the lack of interaction with any DPP4 orthologs tested. 5/18 https://t.co/hhkPDArzAp https://t.co/Pi0oxLCz1J https://t.co/sSQcybzmLP
This video explores how specific bat coronaviruses can infect humans, highlighting research on trypsin treatment to overcome infection barriers. Key findings suggest that both receptor binding and spike protein cleavage…
@justinmsizemore @angoffinet Baric showed that receptor cleavage *unlocked* the species barrier for Covid infection— suspected an FCS-bearing Covid would infect mammals [humans] beyond bats. https://t.co/I4v9fQs7Pj
@CharlesRixey @Fynnderella1 @chrismartenson @zeynep @BillyBostickson @jhas5 would Munster aerosolizing Baric prototype change aerodynamics? Moreover, engineering MERS-like FCS per @ydeigin speaks to bat vax intranasal infectivity as opposed to only gut infection. Heart goes out to you, Charles. https://t.co/TaHkg95hoV
@ydeigin https://t.co/TaHkg95hoV
Com a exemple, els poso un altre estudi fet amb un altre coronavirus, casualment el #HKUCoV, i aquí veuran un nivell de #bioseguretat diferent. De: https://t.co/DujorFAPlX https://t.co/AHSQF3Izcp
@Rebecca21951651 12. Nao, N. et al. MBio 8, e02298-16 (2017). 13. Chan, C.-M. et al. Exp. Biol. Med. 233, 1527–1536 (2008). 14. Follis, K. E., York, J. & Nunberg, J. H. Virology 350, 358–369 (2006). 15. Menachery, V. D. et al. J. Virol. https://t.co/qMMMczmUSf (2019).
@SeekingTruth4us Ralph Baric white paper 2021
These results concur with @TheMenacheryLab @Baric_Lab seminal work on the role of trypsin to overcome barriers for zoonotic bat coronavirus infection 8/21 https://t.co/l1RuGZjJdL
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
RT @jhas5: @arunschirps @AGHuff Fauci got a slight discount for funding Defuse lol But little rascal was able to spread & hide the funding…
RT @MonaRahalkar: This paper was a result of PREDICT program submitted pre-pandemic. Author list includes Menachery, Baric, Barney Graham,…
@breakfast_dogs @BioSRP @mbw61567742 @SolidEvidence @Rebecca21951651 @R_H_Ebright @tony_vandongen @michaelzlin @WashburneAlex @VBruttel @quay_dr It is conserved in several indicating an adaptive benefit This paper claims that the protease rich gut environment actually promotes virus activation (look at the authors though) https://t.co/7xb9VH56kx
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
@Daoyu15 @DrLiMengYAN1 Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection https://t.co/ochqdd1QfZ https://t.co/U0W4ODScPC
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
@butlerofdogs @RobTownley6 @Ayjchan @wanderer_jasnah https://t.co/7MtZ1iUTzs if you want to read, plenty of other examples, this region was a frequent focus of research and experimentation re: both vaccines and antivirals.
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection | Journal of Virology https://t.co/GSKWv61cgy
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
@G_Commish @ejustin46 @Nk9992Nk @supertodd1 @amcalber @dgurdasani1 @VirusesImmunity @EricTopol @Twitter HKU4/HKU5 https://t.co/Z3qhxJOuHf https://t.co/nJGJZj4Pyp https://t.co/Ivy2ILKg6s https://t.co/IFBOqvKTB0
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
RT @Ayjchan: Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to g…
Virus hunters had supplemented their media with trypsin to help recover novel coronaviruses that were otherwise difficult to grow in the lab. But this also helps to prevent furin cleavage sites from being selected against. https://t.co/ykXK9258eS
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: @BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NI…
RT @jhas5: @BillyBostickson Baric added to preprint (from Sept 2019 to Feb 2020) this RXXR paragraph and fig 6 https://t.co/v0EeyHazMp htt…
RT @MonaRahalkar: This paper was a result of PREDICT program submitted pre-pandemic. Author list includes Menachery, Baric, Barney Graham,…
This paper was a result of PREDICT program submitted pre-pandemic. Author list includes Menachery, Baric, Barney Graham, Lipkin. https://t.co/e3ZgbuCxcd
RT @CD57227: @MonaRahalkar @R_H_Ebright @mattwridley It's this paper: "Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infec…
@MonaRahalkar @R_H_Ebright @mattwridley It's this paper: "Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection" about the MERS / "PDF" chimera (It got rejected by mBio.) https://t.co/0BxkMwjjHB
RT @AntGDuarte: @ydeigin @past_is_future @MJnanostretch @jfjulien @dmoulding @stuartjdneil @Rossana38510044 @mrandersoninneo @JuliaDixon195…
@MAFIA__Russia @gtuckerkellogg @MJnanostretch (I don't know that other labs were not engineering bat CoVs in 2019... I believe at least Baric's was.) https://t.co/fNvTcpNsre
RT @veeslerlab: Designing vaccines eliciting broad merbecovirus immunity is going to be challenging as MERS-CoV & PDF-2180 share only 49% a…
RT @veeslerlab: However, the NeoCoV and PDF-2180 spikes are highly divergent to the MERS-CoV spike in the receptor-binding S1 subunit, expl…
RT @jhas5: @lissnup @innominata_ @stevenemassey Ref #2 https://t.co/v0EeyHazMp
@lissnup @innominata_ @stevenemassey Ref #2 https://t.co/v0EeyHazMp
RT @veeslerlab: Designing vaccines eliciting broad merbecovirus immunity is going to be challenging as MERS-CoV & PDF-2180 share only 49% a…
RT @veeslerlab: However, the NeoCoV and PDF-2180 spikes are highly divergent to the MERS-CoV spike in the receptor-binding S1 subunit, expl…
Designing vaccines eliciting broad merbecovirus immunity is going to be challenging as MERS-CoV & PDF-2180 share only 49% and 34% amino acid sequence identity in their S1 subunit and receptor-binding domains, respectively 17/18 https://t.co/sSQcybzmLP
However, the NeoCoV and PDF-2180 spikes are highly divergent to the MERS-CoV spike in the receptor-binding S1 subunit, explaining the lack of interaction with any DPP4 orthologs tested. 5/18 https://t.co/hhkPDArzAp https://t.co/Pi0oxLCz1J https://t.co/sSQcybzmLP
@RealCheckMarker @Ticklicker56 @Vogelmensch8 @2dedostesta2 @quay_dr It’s a bat vax so targets the GI https://t.co/v0EeyHb7BX
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
@innominata_ @breakfast_dogs @CharlesRixey @tony_vandongen Good point. But for Baric it’s a glimpse into his mind at the time. That RxxR tripsin paper was Defuse funding so he needs to justify primary HAE. Human potential. Human spillover. More $$$ https://t.co/v0EeyHazMp https://t.co/GE4lbkJB5g
@jhas5 @arunschirps Trypsin treatment unlocks barrier for zoonotic bat coronavirus infection https://t.co/PeKv0kkEgw
RT @jhas5: @Daoyu15 @Engineer2The @humblesci Want to know why he used MERS? It’s not on select agent list like SARS so no GoF approvals nee…
RT @jhas5: @Daoyu15 @Engineer2The @humblesci Want to know why he used MERS? It’s not on select agent list like SARS so no GoF approvals nee…
@Daoyu15 @Engineer2The @humblesci Want to know why he used MERS? It’s not on select agent list like SARS so no GoF approvals needed https://t.co/v0EeyHazMp
@NateWeymouth @Rossana38510044 @GigaGerard @Ayjchan @RandPaul @garyruskin Yes he’s in those Fang Li emails MHV is the RGS for SARS2 & Trypsin is a receptor Notice RXXR FCS publish date https://t.co/v0EeyHazMp https://t.co/JgWaODpZCZ
@Daoyu15 @breakfast_dogs @gdemaneuf Sure u knew about this re Omicron but guess who was studying endosomal entry (similar to Sars1) in 2019 https://t.co/v0EeyHazMp https://t.co/znp48d94za
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
@2Genervter @jhas5 @innominata_ @BiotechObserver @a_nineties @Daoyu15 @NaybobNattering @Jikkyleaks @CharlesRixey @jjcouey https://t.co/lXXBHexTjZ https://t.co/8uzJ0IJ5J3
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
RT @jhas5: Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting…
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
RT @JackDempsey2_2: @Rossana38510044 @jhas5 As you point out, *even with the sequence in hand* Baric etal failed to recognize the FCS! Focu…
RT @JackDempsey2_2: @Rossana38510044 @jhas5 As you point out, *even with the sequence in hand* Baric etal failed to recognize the FCS! Focu…
@Rossana38510044 @jhas5 As you point out, *even with the sequence in hand* Baric etal failed to recognize the FCS! Focused on the range of animal hosts that could bind the SARS2 RBD even though his group had shown that enzymatic cleavage EXTENDS infectable host range. https://t.co/5b814cNDfr
RT @GFleao: "Tratamento com tripsina desbloqueia barreira para infecção por coronavírus de morcego zoonótico"
"Tratamento com tripsina desbloqueia barreira para infecção por coronavírus de morcego zoonótico"
RT @jhas5: 7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (…
7. This exact same group of Ralph Lisa Vineet Lipkin etc at exact same time are publishing RXXR at S1/S2 in this 2019-20 paper (~same thing as SARS2) https://t.co/v0EeyHazMp
RT @jhas5: @arunschirps @AGHuff Fauci got a slight discount for funding Defuse lol But little rascal was able to spread & hide the funding…
Baric’s obsession with a human specific FCS goes way back 2010 https://t.co/4iMdo8Rky5 2015 https://t.co/RDCoKH7yRM Infecting bat cells w/ HIV in 2018 https://t.co/sBNVwS87Qa Infecting live bats dreaming of FCS https://t.co/ZGqCZNDmf2 RXXR in 2019 https://t.co/v0EeyHazMp
@TexasLindsay @Daoyu15 @AGHuff Lindsay, A, great interview! Pls send this list of papers to Malone. It’s Fauci $$$ (pre) Defuse work. Tell him only Wuhan had Horseshoe bat colony for aerosol test https://t.co/8hrRqPWKiA https://t.co/v0EeyHazMp https://t.co/sBNVwS87Qa https://t.co/RNvpfy2iC2
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @BillyBostickson: Trypsin? Coincidence? 1. Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (2022) https://t.co/rLdO…
RT @jhas5: @arunschirps @AGHuff Fauci got a slight discount for funding Defuse lol But little rascal was able to spread & hide the funding…
RT @jhas5: @Biorealism @arambaut @PeaseRoland @CommonsSTC @stuartjdneil @JeremyFarrar @MRC_Outbreak Yes open secret Defuse ‘type work’ ongo…
@arunschirps @AGHuff Fauci got a slight discount for funding Defuse lol But little rascal was able to spread & hide the funding. All these are (pre) Defuse Baric papers https://t.co/v0EeyHazMp https://t.co/sBNVwS87Qa https://t.co/8hrRqPWKiA https://t.co/n88drBvBIt https://t.co/tZvV5ADFiR
RT @jhas5: @Biorealism @arambaut @PeaseRoland @CommonsSTC @stuartjdneil @JeremyFarrar @MRC_Outbreak Yes open secret Defuse ‘type work’ ongo…
Some infamous work undertaken involving the Center for Infection & Immunity, Mailman School, Columbia University (+UNC, UTMB Galveston, NIAID) Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection https://t.co/LKgaBFnsNq or https://t.co/CNs26jCTty https://t.co/AHUYlC4eEg
@BatResearch NIH Defuse funding list 2018-19: https://t.co/v0EeyHazMp https://t.co/sBNVwS87Qa https://t.co/RNvpfy2iC2 Pls tell me what U know about Danielle Anderson? Ferret specialist? https://t.co/Jih2Z0QAPD
RT @mipardudire: @catibra Debe ser otro escape de laboratorio, desde el 2019 se conocen clones de Mers. https://t.co/1TKXTLUmJS Los merbeco…
@BillyBostickson @AGHuff 2019 (pre) Defuse paper https://t.co/v0EeyHazMp https://t.co/XvxMr8b7lj
RT @FoolsMultiply: @jhas5 @BiophysicsFL @BillyBostickson Any coincidence that today's talk-of-the-town #PDF2180 is the subject of that same…
@catibra Debe ser otro escape de laboratorio, desde el 2019 se conocen clones de Mers. https://t.co/1TKXTLUmJS Los merbecovirus(Neocov) no usan el receptor ACE2 humano sino CD26, y los q lo usan carecen del FCS dónde se produce la escisión(separación) de las subunidades del pico(S1/S2). https://t.co/JQLYRKpJhJ
@jhas5 @BiophysicsFL @BillyBostickson Any coincidence that today's talk-of-the-town #PDF2180 is the subject of that same paper? #Mers #Baric https://t.co/q6aP0PIwro https://t.co/9KCGAdfOCW
@alexandrosM @Florin_Uncovers @Maestermagoo @stuartjdneil @P_J_Buckhaults @scotub Lipkin emails would shed most light He’s also on this (pre) Defuse paper (RXXR at S1/S2) with Baric & Barney https://t.co/v0EeyHazMp https://t.co/QXVeU8EFaE
RT @jhas5: @Undergroundcou1 @KathMLee1 @KevinMcH3 @luigi_warren @NoWackyScience @CharlesRixey So u don’t think this 2019 paper with Baric L…
@Undergroundcou1 @KathMLee1 @KevinMcH3 @luigi_warren @NoWackyScience @CharlesRixey So u don’t think this 2019 paper with Baric Lipkin Barney is (pre) Defuse work with NIH $ ? RXXR at S1/S2? RBD (from Laos via NMRCA-A) https://t.co/v0EeyHazMp https://t.co/lpcyHMnKlW
RT @fynn_fan:
@Biorealism @arambaut @PeaseRoland @CommonsSTC @stuartjdneil @JeremyFarrar @MRC_Outbreak Yes open secret Defuse ‘type work’ ongoing & funded See here 2019 with Baric Barney & Lipkin “results argue both RBD & proteolytic cleavage of spike are critical factors must be considered for evaluating emergence & risk posed by zoonotic coronaviruses” https://t.co/v0EeyHb7BX
@RogerMarshallMD “Moving forward, the results argue that both RBD & proteolytic cleavage of the spike are critical factors that must be considered for evaluating the emergence potential and risk posed by zoonotic coronaviruses” https://t.co/v0EeyHazMp
@Undergroundcou1 @CharlesRixey @rareearths Bits of Defuse were already funded “proteolytic cleavage is the primary barrier to infection for a subset of zoonotic coronaviruses” https://t.co/v0EeyHazMp “inoculation study using Chinese horseshoe bats, from which WIV1-CoV was originally isolated” https://t.co/RNvpfy2iC2
RT @judah_ariella: First read this and then read the paper again: https://t.co/NX2mVouRj2 https://t.co/sViN6Psmzx
RT @judah_ariella: https://t.co/NX2mVouRj2 https://t.co/1vsMF0MhZt
RT @judah_ariella: https://t.co/NX2mVouRj2
RT @judah_ariella: https://t.co/NX2mVouRj2 https://t.co/HybbGzITHp
First read this and then read the paper again: https://t.co/NX2mVouRj2 https://t.co/sViN6Psmzx
https://t.co/NX2mVouRj2 https://t.co/1vsMF0MhZt
https://t.co/NX2mVouRj2 https://t.co/HybbGzITHp
RT @judah_ariella: https://t.co/NX2mVouRj2
https://t.co/NX2mVouRj2
RT @SixandLaura: Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection Received 10/16/2019 Accepted 11/27/2019 Accepted…
RT @jhas5: @BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NI…
RT @jhas5: @BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NI…
RT @jhas5: @BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NI…
RT @jhas5: @BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NI…
@BiophysicsFL @FoolsMultiply @BillyBostickson I believe that Sept 2019 to Feb 2020 paper with Lipkin Baric Graham is the last NIIAID paper honestly discussing (RXXR) cleavage sites https://t.co/v0EeyHazMp
RT @jhas5: @BillyBostickson Baric added to preprint (from Sept 2019 to Feb 2020) this RXXR paragraph and fig 6 https://t.co/v0EeyHazMp htt…
RT @SixandLaura: Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection Received 10/16/2019 Accepted 11/27/2019 Accepted…
RT @SixandLaura: Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection Received 10/16/2019 Accepted 11/27/2019 Accepted…
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection Received 10/16/2019 Accepted 11/27/2019 Accepted manuscript posted online 12/4/2019 #sarscov2 #diabetes #pancreas #proteolytic_cleavage #MERS #protease #HKU5-CoV #tropism #pulmonary https://t.co/JX7pFJEpgA https://t.co/B59N5fotmg
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection - PubMed https://t.co/w8ZjmOFcz7
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection https://t.co/EA5q1aHT2l
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection | Journal of Virology https://t.co/hCBlMrqi63
Notice Freudian slip of tongue at 4min: my UTMB lab developed Furin KO virus last couple errrrr last year. https://t.co/qoup80scTO His paper right before Covid leaked found the furin cleavage are ‘critical’ to human infection poss causing Indigestion https://t.co/uqyePNMmSY
@ydeigin now convinced the RRAR cleavage came from UTMB Galveston BSL4. Fw’d to 4min Mark. Freudian slip of tongue? https://t.co/qoup80scTO Vineets 2019 paper discusses cleavage, digestive track infection, etc https://t.co/xoSwKqsYSn
@KevinMccairn now convinced the RRAR cleavage came from UTMB Galveston BSL4 (which was pop w/ Chinese nationals). Fw’d to 4min Mark. Freudian slip of tongue? https://t.co/qoup80scTO Vineets 2019 paper discusses cleavage, digestive track infection, etc https://t.co/uqyePNMmSY
Vineet’s 2019 UTMB Galvez paper find “both receptor binding & proteolytic cleavage of the spike are critical factors...and other tissues, incl digestive tract, could be a site for future coronavirus emergence events in humans” Probably why Covid in sewers. https://t.co/uqyePNMmSY
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
RT @BillyBostickson: 15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future co…
15. And guess who found out? Uncle Ralph! "other tissues, including the digestive tract, could be a site for future coronavirus emergence events in humans" Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection (2019) https://t.co/igsmAKqgME https://t.co/CC2CmyLhZH
RT @BillyBostickson: 1/2 Ralph Baric's Spooky Reading List (Rockefeller University) https://t.co/f5qv5ytCcf 1. Trypsin Treatment Unlocks Ba…
RT @BillyBostickson: 1/2 Ralph Baric's Spooky Reading List (Rockefeller University) https://t.co/f5qv5ytCcf 1. Trypsin Treatment Unlocks Ba…
RT @BillyBostickson: 1/2 Ralph Baric's Spooky Reading List (Rockefeller University) https://t.co/f5qv5ytCcf 1. Trypsin Treatment Unlocks Ba…
RT @BillyBostickson: 1/2 Ralph Baric's Spooky Reading List (Rockefeller University) https://t.co/f5qv5ytCcf 1. Trypsin Treatment Unlocks Ba…
1/2 Ralph Baric's Spooky Reading List (Rockefeller University) https://t.co/f5qv5ytCcf 1. Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection https://t.co/p7KK8D4twr 2. Precision mouse models with expanded tropism for human pathogens https://t.co/Bbs20D0vbi https://t.co/r3Nxa3ix9W
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection | J of Virol: „zoonotic SARS-like viruses circulating in Southeast Asian bats are capable of infecting human cells by binding to the known human ACE2 receptor without adaptation“ https://t.co/llgrqHiP6P
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection https://t.co/swjpDOTPjX
@balajis Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection: https://t.co/uRykIDzK3p Trypsin from pancreas self activates in duodenum - receptor free infection? https://t.co/nGzY6GckCM
#SARSCoV2 News & Updates AgNP Protection >> https://t.co/UEOI8INnwS << @thelonevirologi: Trypsin Treatment Unlocks Barrier for Zoonotic Bat #Coronavirus Infection https://t.co/yyCVP1HAgv
Trypsin treatment unlocks barrier for zoonotic bat coronaviruses infection. J Virol. 2019 Dec 4. pii: JVI.01774-19. https://t.co/TmfBzviWzX #batpapers #batCoV #trypsin #notthesameinourhands