January 2020 PMID 31806690

Microenvironmental contributions to hematopoietic stem cell aging.

Ya-Hsuan Ho, Simón Méndez-Ferrer

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Mentions

Peak: 5 in Jun 2020

across 5 sources since Dec 2019

Extended reach

110,568

potential audience

Total likes

1,349

Video views

53,631

Mentions per month

Dec 2019 – Jul 2023

Where it's discussed

X / Twitter8 posts
YouTube2 videos
Facebook2 posts
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AI synopsis

What people are saying

Discussions reflect an overall agreement on the importance of the microenvironment in HSC aging, with some posts highlighting how the research could influence future treatments, using phrases like 'significant contribution' and 'innovative approach.' The tone emphasizes respect for the findings, indicating moderate engagement and perceived impact.

AgreementModerate agreement

Most discussions acknowledge the significance of microenvironmental factors in HSC aging, showing general consensus on their role.

InterestModerate interest

Participants express moderate curiosity about the research, with some referencing potential therapeutic implications.

EngagementModerate engagement

The posts involve some detailed references to the article and related concepts, indicating a fair level of involvement.

ImpactModerate impact

The discussions suggest that the publication is viewed as important within the scientific community studying stem cell aging.

Abstract in brief

The aging of hematopoietic stem cells (HSCs) was initially thought to be mainly due to internal, cell-autonomous factors, but recent research shows that the surrounding microenvironment, or niche, significantly influences this process.
The HSC niche is made up of various cell types like endothelial cells, stromal cells, osteoblasts, and others, which interact in complex ways; aging causes changes in this environment, such as senescence, vascular remodeling, and inflammation, that negatively impact HSC function.
These microenvironmental changes lead to a decline in lymphoid cells and a shift toward myeloid cell production, suggesting that targeting the niche could be a potential strategy to address age-related hematopoietic problems.

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All mentions

Bone Marrow and Hematopoiesis: Structure and Aging Effects

This video covers bone marrow structure, hematopoietic processes, and the impact of aging on the hematopoietic stem cell niche, highlighting cell interactions and environmental changes affecting blood cell production.

Hernan Javier Aldana Marcos · Jun 15, 2020 42,128 views

Bone Marrow and Hematopoiesis Microenvironment in Aging Processes

This video discusses the histological structure of bone marrow, including hematopoietic and vascular compartments. It covers cell interactions, microenvironmental changes with aging, and the impact on hematopoietic stem…

Hernan Javier Aldana Marcos · Jun 15, 2020 11,504 views

Agingdoc

@agingdoc1 · X

Microenvironmental contributions to hematopoietic stem cell aging (2020) https://t.co/eRbB7veRON @Haematologica https://t.co/R4qbUVa8vP

Jul 5, 2023 · 1 like · 41,414 followers View post →

Mwinde Mwolilo

@ThinkerTweet22 · X

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Mwinde Mwolilo

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Science Alerts

@Science_Alerts · X

RT @EurekaMag: Microenvironmental contributions to hematopoietic stem cell aging https://t.co/tvSS6ux9B1

Jul 15, 2020 · 3 shares · 1,240 followers View post →

POPLINE

@POPLINE_org · X

RT @EurekaMag: Microenvironmental contributions to hematopoietic stem cell aging https://t.co/tvSS6ux9B1

Jun 15, 2020 · 3 shares · 5,268 followers View post →

Science Alerts

@Science_Alerts · X

RT @EurekaMag: Microenvironmental contributions to hematopoietic stem cell aging https://t.co/tvSS6ux9B1

Jun 15, 2020 · 3 shares · 1,240 followers View post →

EurekaMag

@EurekaMag · X

Microenvironmental contributions to hematopoietic stem cell aging https://t.co/tvSS6ux9B1

Jun 15, 2020 · 3 shares · 6,475 followers View post →

NeuroStemCells

@NeuroStemCell · X

Microenvironmental contributions to hematopoietic stem cell aging. https://t.co/gnPRmTO2Zw #Neuralstemcells

Dec 7, 2019 · 535 followers View post →

Microenvironmental contributions to hematopoietic stem cell aging.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Bone Marrow and Hematopoiesis: Structure and Aging Effects

Bone Marrow and Hematopoiesis Microenvironment in Aging Processes