ACS Nano December 2019 PMID 31815423

Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant to Meropenem.

Thushara Galbadage, Dongdong Liu, Lawrence B Alemany, Robert Pal, James M Tour, Richard S Gunasekera, Jeffrey D Cirillo

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Mentions

Peak: 22 in Dec 2019

across 6 sources since Dec 2019

Extended reach

79,328

potential audience

Total likes

105

Video views

1,973

Mentions per month

Dec 2019 – Aug 2025

Where it's discussed

X / Twitter37 posts
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Blogs8 articles
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YouTube2 videos

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What people are saying

Discussions around the article reflect a high level of enthusiasm and support, exemplified by phrases like 'Amazing work' and 'good news,' which underscore enthusiasm. The use of scientific terminology such as 'molecular nanomachines' and 'nanodrills' combined with optimistic phrases like 'disrupt bacterial cell walls' and 'increase sensitivity to antibiotics' demonstrate strong engagement and belief in the research's potential impact.

AgreementStrong agreement

Most discussions strongly support the significance of the research, frequently highlighting the innovative use of nanomachines to combat resistant bacteria as a breakthrough.

InterestHigh interest

Posts demonstrate high curiosity and enthusiasm, with many references to 'molecular drills,' 'nanorobots,' and the promising potential of this technology for future treatments.

EngagementHigh engagement

Several posts delve into technical details and implications, discussing how nanomachines disrupt bacterial walls and enable antibiotics to work again, indicating deep engagement.

ImpactHigh impact

Many posts emphasize the revolutionary potential of this research, describing it as a 'game changer' for fighting drug-resistant infections and mentioning the possibility of a significant impact on medicine.

Abstract in brief

Molecular nanomachines (MNMs) can physically disrupt bacterial cell walls by drilling into them, which increases the bacteria's sensitivity to antibiotics like Meropenem.
In experiments, light-activated MNMs combined with Meropenem were able to kill bacteria that were previously resistant, suggesting a way to overcome drug resistance.
The study used permeability tests and microscopy to show that MNMs weaken the bacterial cell wall, making previously ineffective antibiotics work better against resistant bacteria.]

Read the full abstract

All mentions

Advances in Nanomedicine and Its Implications for Healing and Disease Treatment

Join biochemists Fazale Fuz Rana and Richard Gunasekera as they discuss breakthroughs in nanomedicine, including nanomachines that disrupt microbial defenses and target cancer cells, highlighting how scientific…

Reasons to Believe · Aug 20, 2025 1,724 views

Using Molecular NanoMachines to Combat Antibiotic Resistance

Molecular nanomachines can physically disrupt bacterial cell walls, increasing antibiotic sensitivity. Dr. Jeffrey D Cirillo discusses how light-activated MNMs combined with antibiotics can overcome drug resistance and…

GenScript USA Inc. · Feb 8, 2020 249 views

Brian Stevenson

@Ashitaka1110 · X

RT @RTB_FRana: Does Divine healing occur? How does God heal? Can science offer any perspective on God's healing work? I am joined by Dr. R…

Aug 22, 2025 · 1 share · 795 followers View post →

Fazale “Fuz” Rana

@RTB_FRana · X

Aug 22, 2025 · 5 likes · 1 share · 7,116 followers View post →

Dimon Luka

@DimonvLuka · X

https://t.co/TpZH9hMus1 problem solved already, use nanorobots https://t.co/09sSvchJBX

Apr 6, 2021 · 81 followers View post →

Wendy Morgado Gamero

@WENDYMORGADO4 · X

RT @GloriaHan18: Check out Dr. Jeffrey Cirillo's new paper in ACS here: https://t.co/pIXtFJSwxc https://t.co/NrUqYSYnhP

Jan 18, 2021 · 3 shares · 36 followers View post →

G. Hak.

@G11911 · X

Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumoniae to Meropenem https://t.co/hp6k43Kc8V

Apr 9, 2020 · 634 followers View post →

Tina Dadic

@SunceMore1 · X

RT @GloriaHan18: Check out Dr. Jeffrey Cirillo's new paper in ACS here: https://t.co/pIXtFJSwxc https://t.co/NrUqYSYnhP

Mar 30, 2020 · 3 shares · 1,411 followers View post →

Gary Beane

@pollinus66 · X

RT @GloriaHan18: Check out Dr. Jeffrey Cirillo's new paper in ACS here: https://t.co/pIXtFJSwxc https://t.co/NrUqYSYnhP

Mar 30, 2020 · 3 shares · 2,024 followers View post →

Gloria Han

@GloriaHan18 · X

Check out Dr. Jeffrey Cirillo's new paper in ACS here: https://t.co/pIXtFJSwxc https://t.co/NrUqYSYnhP

Mar 30, 2020 · 3 likes · 3 shares · 4 followers View post →

GenScript

@GenScript · X

RT @MolecularCloud3: Good Morning! We will now be making bite-sized education videos on our Cloud Scientist's publications. Check out Dr. J…

Feb 11, 2020 · 2 shares · 8,594 followers View post →

Gary Beane

@pollinus66 · X

RT @MolecularCloud3: Good Morning! We will now be making bite-sized education videos on our Cloud Scientist's publications. Check out Dr. J…

Feb 6, 2020 · 2 shares · 2,024 followers View post →

MolecularCloud

@MolecularCloud3 · X

Feb 6, 2020 · 3 likes · 2 shares · 239 followers View post →

Gary Beane

@pollinus66 · X

RT @MicahJGreen: Amazing work from the Tour group at Rice showing “molecular drills” going after antibiotic-resistant bacteria (@acsnano) h…

Jan 12, 2020 · 1 share · 2,024 followers View post →

Micah Green

@MicahJGreen · X

Amazing work from the Tour group at Rice showing “molecular drills” going after antibiotic-resistant bacteria (@acsnano) https://t.co/UpCR5ssXJv

Jan 12, 2020 · 3 likes · 1 share · 2,141 followers View post →

Gary Beane

@pollinus66 · X

RT @EMacherki: Some one use #nano to beat #bacteria : Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensi…

Jan 7, 2020 · 1 share · 2,024 followers View post →

Macherki M E

@EMacherki · X

Some one use #nano to beat #bacteria : Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumoniae to Meropenem https://t.co/TG5lfNBMDs

Jan 7, 2020 · 1 share · 322 followers View post →

Mar Herrador

@MarHerrador · X

RT @MedicinaCEU: Nuevas investigaciones apuntan a que los nanomateriales pueden ser usados de manera eficaz para el tratamiento de enfermed…

Dec 18, 2019 · 2 shares · 194 followers View post →

J_Robert_P_M

@J_Robert_P_M · X

https://t.co/phzyY3mUPp

Dec 17, 2019 · 703 followers View post →

Gary Beane

@pollinus66 · X

RT @MedicinaCEU: Nuevas investigaciones apuntan a que los nanomateriales pueden ser usados de manera eficaz para el tratamiento de enfermed…

Dec 17, 2019 · 2 shares · 2,024 followers View post →

USPCEU Medicina

@uspceumedicina · X

Nuevas investigaciones apuntan a que los nanomateriales pueden ser usados de manera eficaz para el tratamiento de enfermedades infecciosas y tumores. https://t.co/LxFzUDo4yD https://t.co/itXqloMBVQ

Dec 17, 2019 · 4 likes · 2 shares · 937 followers View post →

Gary Beane

@pollinus66 · X

RT @LEMacKz: Q: How can redundant #antibiotics kill resistant bacteria? A: By using nanodrills to punch holes in the bacterial cell wall…

Dec 16, 2019 · 1 share · 2,024 followers View post →

Lewis MacKenzie

@LEMacKz · X

Q: How can redundant #antibiotics kill resistant bacteria? A: By using nanodrills to punch holes in the bacterial cell wall first! A new strategy in our fight against #antibiotic resistant bacteria, out in @acsnano. @PalRobek @DurhamChemistry https://t.co/7m6Q1qDRkf https://t.co/u9kXLTnFzQ

Dec 16, 2019 · 2 likes · 1 share · 4,635 followers View post →

Gary Beane

@pollinus66 · X

RT @isaackraz: Bacteria-killing nanodrills! https://t.co/Rjd1UeyjBt

Dec 15, 2019 · 1 share · 2,024 followers View post →

Isaac Krasnopolsky, M.S.

@isaackraz · X

Bacteria-killing nanodrills! https://t.co/Rjd1UeyjBt

Dec 15, 2019 · 1 share · 159 followers View post →

刘栋栋

@sniper3668 · X

RT @DGalbadage: Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumon…

Dec 14, 2019 · 1 share · 5 followers View post →

Vivek Mutalik

@vivek_mutalik · X

RT @CarlosMtzS93: Can picture a #phage with drills attached to it

Dec 13, 2019 · 4 shares · 5,175 followers View post →

Gary Beane

@pollinus66 · X

RT @afifpj: Molecular drill could break the shield of MDR-Klebsiella pneumoniae and allow the antibiotics do their jobs once again.. https…

Dec 13, 2019 · 1 share · 2,024 followers View post →

Afif Pranaya Jati

@afifpj · X

Molecular drill could break the shield of MDR-Klebsiella pneumoniae and allow the antibiotics do their jobs once again.. https://t.co/p5NjUdk30a

Dec 13, 2019 · 1 share · 1,136 followers View post →

Dr Ellie Jameson

@Ellie__Jameson · X

RT @CarlosMtzS93: Can picture a #phage with drills attached to it

Dec 13, 2019 · 4 shares · 3,883 followers View post →

Science news

@UpdateonScience · X

https://t.co/XC2RxBda3w Molecular nanomachines have been used to disrupt bacterial cell walls, increasing their sensitivity to antibiotics that were previously ineffective. #sciencenews https://t.co/EasXyjIsZ9

Dec 13, 2019 · 1 share · 1,883 followers View post →

Gary Beane

@pollinus66 · X

RT @CarlosMtzS93: Can picture a #phage with drills attached to it

Dec 13, 2019 · 4 shares · 2,024 followers View post →

Dr. Sabrina Green, PhD

@MotherOfPhage · X

RT @CarlosMtzS93: Can picture a #phage with drills attached to it

Dec 13, 2019 · 4 shares · 13,221 followers View post →

Carlos Martínez

@CarlosMtzS93 · X

Can picture a #phage with drills attached to it

Dec 13, 2019 · 13 likes · 4 shares · 87 followers View post →

Gary Beane

@pollinus66 · X

RT @GVlasuk: Innovation-Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella…

Dec 13, 2019 · 1 share · 2,024 followers View post →

George Vlasuk

@GVlasuk · X

Innovation-Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumoniae to Meropenem:https://t.co/HJ2Ik1WGWN

Dec 13, 2019 · 1 share · 1,424 followers View post →

Don T. Galbadage

@DGalbadage · X

Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumoniae to Meropenem https://t.co/6tluAXsqiU

Dec 12, 2019 · 1 like · 1 share · 7 followers View post →

Gary Beane

@pollinus66 · X

RT @jdcZZZ: Got a nice paper out in ACS Nano: https://t.co/HolYIXcK4s And Rice University put out a nice press release about it, thanks! h…

Dec 12, 2019 · 1 share · 2,024 followers View post →

Jeffrey Cirillo

@jdcZZZ · X

Got a nice paper out in ACS Nano: https://t.co/HolYIXcK4s And Rice University put out a nice press release about it, thanks! https://t.co/YLU5zeN5Jh…/deadly-superbugs-destroyed-by-mole…/

Dec 12, 2019 · 1 like · 1 share · 144 followers View post →

Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant to Meropenem.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Advances in Nanomedicine and Its Implications for Healing and Disease Treatment

Using Molecular NanoMachines to Combat Antibiotic Resistance