N Engl J Med January 2020 PMID 31851795

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

Eric F Morand, Richard Furie, Yoshiya Tanaka, Ian N Bruce, Anca D Askanase, Christophe Richez, Sang-Cheol Bae, Philip Z Brohawn, Lilia Pineda, Anna Berglind, Raj Tummala

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Mentions

180
Peak: 64 in Dec 2019
across 8 sources since Dec 2019

Extended reach

3,459,256
potential audience

Total likes

285

Video views

4,868

Mentions per month

Dec 2019 – Dec 2025

Where it's discussed

  • X / Twitter150 posts
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AI synopsis

What people are saying

The overall tone indicates a high level of interest, with many commenters referencing successful trial results and potential new treatments, evidenced by phrases like 'good news,' 'positive results,' and 'high response rates.' The tone shifts slightly with some posts expressing cautious optimism or skepticism, especially regarding side effects like herpes zoster, which reflects a nuanced view on the trial's impact and significance.

AgreementModerate agreement

Most discussions show support or positive recognition of the trial's findings, reflecting consensus about the potential of anifrolumab, despite some expressed uncertainties.

InterestHigh interest

The posts demonstrate high interest in the research, with multiple references to trial outcomes, drug development, and clinical implications.

EngagementModerate engagement

Participants show moderate engagement, sharing detailed information, citing specific trials like TULIP-2, and discussing side effects and future potential.

ImpactModerate impact

The discussions suggest a moderate to high impact, highlighting the importance of these findings for future SLE therapies, though some remain cautious or awaiting further evidence.

Abstract in brief

  • Anifrolumab, a drug targeting the type I interferon receptor, was tested in a phase 3 trial for systemic lupus erythematosus (SLE) but did not meet its primary endpoint in a previous study; this trial used a different, more secondary endpoint for evaluation.
  • In the study, patients were randomly assigned to receive either anifrolumab or placebo for 48 weeks, with the main goal being a response at week 52 based on improvements in disease activity measures like BILAG and other assessments; secondary outcomes included reductions in medication use and symptom severity.
  • The results showed that about 47.8% of patients on anifrolumab responded compared to 31.5% on placebo, indicating a significant treatment effect, especially in patients with a high interferon gene signature, suggesting the drug may be more effective for certain subgroups of SLE patients.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 54 likes · 27 shares · 931,425 followers View post →
NEJM
@NEJM · X

A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite primary end point of lupus scores. https://t.co/PwZnsYSu2F

Jan 15, 2020 · 46 likes · 28 shares · 931,425 followers View post →
FabriceAndre
@FAndreMD · X

18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001), a randomized trial shows that Anifrolumab is effective in SLE. A very good illustration of translational science https://t.co/2mXHYHeAtZ

Dec 25, 2019 · 23 likes · 10 shares · 15,267 followers View post →
NEJM
@NEJM · X

Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 21 likes · 14 shares · 931,425 followers View post →
Annals of the Rheumatic Diseases
@eular_ARD · X

Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparing for the turn of the year.

Dec 31, 2019 · 11 likes · 6 shares · 13,089 followers View post →
Cyrus | Mastodon in bio
@CyruxiME · X

When you have an under-researched chronic illness like #MECFS, a large, well-designed, pharma-funded trial of a treatment for a dynamically disabling disease is a marvel to behold. High quality evidence from rigorous trials can’t come soon enough. https://t.co/tcsMDdixm5

Sep 16, 2022 · 9 likes · 1,518 followers View post →

All mentions

Cindy
@cindyorozcob · X

Sep 18, 2025 · 1 like · 349 followers View post →
saori abe inoue
@ori_114 · X

Tulip2 trials

Aug 27, 2024 · 7 likes · 813 followers View post →
Prof Liz B
@kidneydoc101 · X

RT @chriswincup: And there is good news! ⭐️ Clinical trials are starting to show successful use of targeted therapies. Most recently with…

Mar 17, 2024 · 1 share · 11,969 followers View post →
Chris Wincup
@chriswincup · X

And there is good news! ⭐️ Clinical trials are starting to show successful use of targeted therapies. Most recently with the positive Phase III for Anifrolumab by @EricFMorand et al This means we may be better at achieving those targets in the future

Mar 17, 2024 · 3 likes · 1 share · 5,353 followers View post →
فاطمة البارقي
@Fatma59567605 · X

https://t.co/oUncRnd5th

Sep 2, 2023 · 35 followers View post →
YNP of ERA
@ynptweets · X

9/ Please find below the specific side effects of TULIP, TULIP-LN, and a sub-analysis of the WGET trial. https://t.co/4oVzZXuJSm https://t.co/eN4jgLPIBn https://t.co/AyH2hY4dd9

Jul 25, 2023 · 1 like · 3,821 followers View post →
Monisha Madhumita
@DrMonisha_MD · X

New drugs in the pipeline for CLE - https://t.co/ytFAbRilUE https://t.co/ZepRJuf4Nl https://t.co/JE5vjPuYmH

Jun 19, 2023 · 555 followers View post →
Monisha Madhumita
@DrMonisha_MD · X

Anifrolumab is efficacious for CLE but currently only approved for SLE - https://t.co/ZepRJuf4Nl

Jun 19, 2023 · 555 followers View post →
Cyrus | Mastodon in bio
@CyruxiME · X

When you have an under-researched chronic illness like #MECFS, a large, well-designed, pharma-funded trial of a treatment for a dynamically disabling disease is a marvel to behold. High quality evidence from rigorous trials can’t come soon enough. https://t.co/tcsMDdixm5

Sep 16, 2022 · 9 likes · 1,518 followers View post →
AMA Manual of Style
@AMAManual · X

Thx for example. This is an online-only supplement. Morand EF, Furie R, Tanaka Y, et al. Trial of anifrolumab in active systemic lupus erythematosus. Supplement 2. N Engl J Med. 2020;382:211-221. Access date. URL https://t.co/7aho7wVDow

Jun 17, 2022 · 1 like · 6,140 followers View post →
Carlota Gudiol
@Carlotasway3 · X

RT @davidvanduin: Dr Fernandez Ruiz now covers anifrolumab (anti-interferon receptor) for SLE. ⬆️⬆️⬆️ risk of H. zoster #ECCMID2022 http…

Apr 23, 2022 · 2 shares · 1,169 followers View post →
Michael Ison, MD MS
@MichaelGIsonMD · X

RT @davidvanduin: Dr Fernandez Ruiz now covers anifrolumab (anti-interferon receptor) for SLE. ⬆️⬆️⬆️ risk of H. zoster #ECCMID2022 http…

Apr 23, 2022 · 2 shares · 4,986 followers View post →
David van Duin
@davidvanduin · X

Dr Fernandez Ruiz now covers anifrolumab (anti-interferon receptor) for SLE. ⬆️⬆️⬆️ risk of H. zoster #ECCMID2022 https://t.co/LUGK6Vnh0s

Apr 23, 2022 · 5 likes · 2 shares · 3,992 followers View post →
鯵ゼミ_Journal Club
@AJSR_since2005 · X

#086 Trial of Anifrolumab in Active Systemic Lupus Erythematosus N Engl J Med 2020;382:211-21. TULIP-2試験 活動性のSLEに対するアニフロルマブは、プラセボと比較して、52週後の奏効(BICLAで評価)を認める割合が高かった

Apr 2, 2022 · 6 followers View post →
Dr Omar Eloy Muñoz
@omaremm28 · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 11, 2021 · 8 shares · 319 followers View post →
Santiago Arellano
@santiag31227996 · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 10, 2021 · 8 shares · 56 followers View post →
Hugo Rubalcava
@HugoRubalcava · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 10, 2021 · 8 shares · 260 followers View post →
Celso Zamparo
@CelsoZamparo · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 10, 2021 · 8 shares · 317 followers View post →
Jose Luis Morell
@JlMorell · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 10, 2021 · 8 shares · 2,772 followers View post →
mariajosem
@mariaj_morenom · X

RT @JesusLoarce: 1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial…

Aug 10, 2021 · 8 shares · 2,867 followers View post →
Jesús Loarce
@JesusLoarce · X

1) Trial of Anifrolumab in Active Systemic Lupus Erythematosus (TULIP-2) ➡️Phase III, randomized, placebo-controlled trial. 52 weeks. ➡️Recently approved by the FDA. https://t.co/39fOoqu6GK https://t.co/thzegczmG4 #Lupus #Rheumatology

Aug 10, 2021 · 9 likes · 8 shares · 876 followers View post →
د/عبدالله القرني Abdullah Algarni
@abaidalgarni · X

MUSE trial https://t.co/bKjstSMrsp TULIP-I trial https://t.co/rDtUn1f20D TULIP-II trial https://t.co/zEkWRTs9Sa

Aug 3, 2021 · 2,056 followers View post →
帝京リウマチ_Teikyo Rheumatology
@Teikyo_R · X

昨日FDAがSLEに認可。AnifrolumabはI型インターフェロン受容体に対する抗体です。SLEの複合活動性指標BICLAの改善が示されています。IFNシグナチャーが明らかな患者さんで有効率高し。副作用は感染症特に帯状疱疹。PMID: 31851795 https://t.co/WrJtmHo09l

Aug 3, 2021 · 1 like · 476 followers View post →
Madeleine Armstrong
@ByMadeleineA · X

@PearlF @anandcpatelmdms Doesn't look like there was a big difference in response in those with high vs low interferons in Tulip 2 https://t.co/r63CKBzajN https://t.co/v7U0Bgx0r8

Aug 2, 2021 · 1 like · 8,156 followers View post →
Chris Wincup
@chriswincup · X

This was followed by yet more good news from trials in #SLE

Jun 2, 2021 · 3 likes · 5,353 followers View post →
Susan Bernstein
@VelvetBarstool · X

RT @rheum_cat: @JYazdanyMD ⭐SLE trials, both positive

Nov 5, 2020 · 5 shares · 2,041 followers View post →
Joan Von Feldt
@vonfeldt1 · X

RT @rheum_cat: @JYazdanyMD ⭐SLE trials, both positive

Nov 5, 2020 · 5 shares · 602 followers View post →
Suleman Bhana, MD
@DrBhana · X

RT @rheum_cat: @JYazdanyMD ⭐SLE trials, both positive

Nov 5, 2020 · 5 shares · 3,649 followers View post →
Xtel007
@Xtel007 · X

RT @rheum_cat: @JYazdanyMD ⭐SLE trials, both positive

Nov 5, 2020 · 5 shares · 4,768 followers View post →
Rheum Cat
@rheum_cat · X

@JYazdanyMD ⭐SLE trials, both positive

Nov 5, 2020 · 7 likes · 5 shares · 8,902 followers View post →
Strong_bio
@strong_bio · X

RT @PA_Maday: TULIP-2 Trial Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/DfvQhUJ0ov https://t.co/eFVNHcB7E3

Aug 8, 2020 · 1 share · 75 followers View post →
KristopherMaday PA-C
@PA_Maday · X

TULIP-2 Trial Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/DfvQhUJ0ov https://t.co/eFVNHcB7E3

Aug 8, 2020 · 1 share · 2,440 followers View post →
Rheum Journal Club
@RheumJC · X

The articles we will be discussing tonight are the results from TULIP 1 (https://t.co/JQEwuqnpxS) and TULIP 2 (https://t.co/osuoj9zKos). #RheumJC

Feb 27, 2020 · 3 likes · 5,507 followers View post →
minnlab_litbot
@MLitbot · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus. https://t.co/iqTDwTcPVn

Feb 11, 2020 · 71 followers View post →
MoghniUMKCRCT
@MoghniRct · X

This study turned the secondary outcome of TULIP 1 to primary outcome. 1:1 ratio to anifrolumab 300 mg vs placebo x 48 weeks. Primary end point was BICLA. Reached primary end point as 47.8% patients in anifrolumab group had response vs 31.5%. #UMKCRCT https://t.co/tQO26yd4xM

Feb 9, 2020 · 7 followers View post →
Krishan Maggon
@kkmaggon · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/9IsqKeeuQ8 https://t.co/xaMIpFVVZY

Feb 6, 2020 · 999 followers View post →
Didem Saygin, MD
@DidemSayginMD · X

This trial also highlights the importance of development and rigorous validation of outcome measures that are reliable and sensitive to change as they affect the outcome of million dollar trials and approval of drugs that can benefit our patients-TULIP2 https://t.co/KQNi6BZfa2

Feb 5, 2020 · 2 likes · 2,342 followers View post →
cryptoreuMD.eth/3972.⌐◨-◨
@cryptoreumd · X

RT @NatRevRheumatol: #ResearchHighlight | Positive results for anifrolumab in phase III SLE trial #lupus #TULIP2 #anifrolumab #therapy #rh…

Feb 5, 2020 · 3 shares · 2,455 followers View post →
UCD Rheumatology
@UCD_CAR · X

RT @NatRevRheumatol: #ResearchHighlight | Positive results for anifrolumab in phase III SLE trial #lupus #TULIP2 #anifrolumab #therapy #rh…

Feb 5, 2020 · 3 shares · 832 followers View post →
NatRevRheumatol
@NatRevRheumatol · X

#ResearchHighlight | Positive results for anifrolumab in phase III SLE trial #lupus #TULIP2 #anifrolumab #therapy #rheumtwitter Read the original research from @NEJM here https://t.co/wcadoAfDie Read our #news story here https://t.co/zQ1PsrVLAd

Feb 5, 2020 · 6 likes · 3 shares · 19,011 followers View post →
Carlos EncaladaG
@CarlosEncaladaG · X

https://t.co/FNwzLP0ui1

Feb 4, 2020 · 131 followers View post →
Mari
@Mari39086751 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 23, 2020 · 14 shares · 13 followers View post →
Adrian Purcarea
@AdrianPurcarea · X

Bummer https://t.co/ONEEYOpuN6

Jan 22, 2020 · 129 followers View post →
帝京リウマチ_Teikyo Rheumatology
@Teikyo_R · X

抄読会より I型インターフェロン受容体抗体AnifrolumabのSLEにおける有用性が示された。ステロイド減量効果有。新しいお薬になりそうです Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/5KPiB7posx #SLE #ステロイド #anifrolumab #膠原病

Jan 21, 2020 · 3 likes · 3 shares · 476 followers View post →
Pathway
@PathwayMedical · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 20, 2020 · 14 shares · 13,017 followers View post →
Clemen López Medina
@clemenlpez · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 20, 2020 · 14 shares · 341 followers View post →
@UMASMutuaTerrassa
@UMAS_Mutua · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 20, 2020 · 14 shares · 497 followers View post →
Rheumatology & Rheumatology Advances in Practice
@RheumJnl · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 20, 2020 · 14 shares · 12,643 followers View post →
T. A. Marnegie
@TAMarnegie · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 19, 2020 · 14 shares · 139 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 3,386 followers View post →
محذوف
@milardport · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 293 followers View post →
ARGYRO REPA
@arrepa2002 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 20 followers View post →
Last Week in Medicine
@lastweekinmed · X

RT @lastweekinmed: Monthly anifrolumab resulted in a higher percentage of patients with a response at week 52 than did placebo. The frequen…

Jan 18, 2020 · 1 share · 862 followers View post →
LILIANA JÁCOME
@PROLIJASE · X

RT @sebasugarte: Artículo original: Ensayo de anifrolumab en lupus eritematoso sistémico activo https://t.co/VNPvXem28o

Jan 18, 2020 · 1 share · 683 followers View post →
Dr Omar Eloy Muñoz
@omaremm28 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 319 followers View post →
Laboratoire Vieillissement | Fragilité | e-Santé
@LaboratoireVie · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 314 followers View post →
Vicente Lozada-Balderrama
@VicenteLozadaB · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 13,579 followers View post →
SEBASTIAN UGARTE
@sebasugarte · X

Artículo original: Ensayo de anifrolumab en lupus eritematoso sistémico activo https://t.co/VNPvXem28o

Jan 18, 2020 · 1 share · 140,142 followers View post →
ARYAN®
@gladeolie · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 1,491 followers View post →
Pub Health Monitor
@monitor_PH · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 14 shares · 1,816 followers View post →
NEJM
@NEJM · X

Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsZa4Ud

Jan 18, 2020 · 21 likes · 14 shares · 931,425 followers View post →
Lingaraj Nayak
@lingarajnayak · X

31 % response with placebo!! One of the highest ever. Speaks a lot about disease biology Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/uhk0MC0ro2

Jan 18, 2020 · 1 like · 2,328 followers View post →
Raúl Frutos
@RaulfrutosH · X

RT @jlandreu2014: Nueva autorización en ciernes para #Lupus Gran noticia. @Felupus @SEReumatologia @SORCOM1 https://t.co/oxHU0uHckd

Jan 18, 2020 · 10 shares · 388 followers View post →
散歩ミカン
@sanpo_mikan · X

活動性の全身性エリテマトーデスに対するアニフロルマブの試験 Trial of Anifrolumab in Active Systemic Lupus Erythematosus N Engl J Med 2020; 382:211-221 https://t.co/xR8sl7SBSM

Jan 16, 2020 · 338 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/x3JLRByHWC

Jan 16, 2020 · 2,714 followers View post →
JM Martínez Sesmero
@manolosesmero · X

RT @farmaciaclinico: Trial of Anifrolumab in Active Systemic #Lupus Erythematosus @NEJM https://t.co/nNgL16lGvP

Jan 16, 2020 · 1 share · 5,805 followers View post →
Farmacia Clínico
@farmaciaclinico · X

Trial of Anifrolumab in Active Systemic #Lupus Erythematosus @NEJM https://t.co/nNgL16lGvP

Jan 16, 2020 · 1 like · 1 share · 2,425 followers View post →
@investigando
@rocatanho · X

La administración mensual de anifrolumab resultaría en un mayor porcentaje de pacientes con una respuesta en la semana 52. La frecuencia de herpes zóster sería mayor con anifrolumab https://t.co/rRuK9s1ycv

Jan 16, 2020 · 1 like · 395 followers View post →
Professor M Z Khalil
@mzkhalil · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM "The frequency of herpes zoster was higher with anifrolumab than with placebo." https://t.co/MVzRyGa4GU

Jan 15, 2020 · 2,864 followers View post →
RheumWorld
@MattersRheum · X

RT @Tuhina_Neogi: Anifrolumab in #SLE. Two trials. Two different primary outcomes. Two different results. This one was positive: https://t.…

Jan 15, 2020 · 1 share · 984 followers View post →
( ノ´.ㅅ` )ノรางวัลที่ 1 มาแน่!!!
@lexokkaz2 · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 75 followers View post →
Jose Martinez
@jocmaximiliano · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 187 followers View post →
Tuhina Neogi, MD, PhD
@Tuhina_Neogi · X

Anifrolumab in #SLE. Two trials. Two different primary outcomes. Two different results. This one was positive: https://t.co/vqWOQlMikK https://t.co/qPhoPFGvzJ

Jan 15, 2020 · 4 likes · 1 share · 3,141 followers View post →
Lucsob
@sobcuer · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 261 followers View post →
Salva García Morillo PhD. MD.
@UCAMIraras · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 1,064 followers View post →
Lorraine
@Lorrain94741983 · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 941 followers View post →
Olivier Elemento
@ElementoLab · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 6,247 followers View post →
Carlos
@MarvinHarris76 · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 4,521 followers View post →
Xavier Sáez Llorens
@xsaezll · X

RT @NEJM: A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite prim…

Jan 15, 2020 · 28 shares · 128,736 followers View post →
NEJM
@NEJM · X

A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite primary end point of lupus scores. https://t.co/PwZnsYSu2F

Jan 15, 2020 · 46 likes · 28 shares · 931,425 followers View post →
❄病気は頑張りの「 #結晶
@nemunokies · X

RT @Yohei_Kanzawa: マブは追いつけなくなってきました。SLE治療薬、Ⅰ型インターフェロン受容体抗体、アニフロマブ anifromabのRCT。#SLE Trial of Anifrolumab in Active Systemic Lupus Erythema…

Jan 15, 2020 · 1 share · 2,969 followers View post →
Claude Bertrand
@Bertran16Claude · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Jan 12, 2020 · 10 shares · 225 followers View post →
Sandip Thakrar
@Sandip_Thakrar · X

Trial of anifrolumab in active systemic lupus erythematosus https://t.co/nt0WzXNCVy #m3india

Jan 5, 2020 · 287 followers View post →
官澤洋平 YK Hospitalist
@Yohei_Kanzawa · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM #アニフロルマブ #anifrolumab https://t.co/SqWGBywkEb

Jan 4, 2020 · 3,304 followers View post →
Jean-Guillaume Letarouilly
@JGLetarouilly · X

RT @ARD_BMJ: Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparin…

Jan 2, 2020 · 6 shares · 626 followers View post →
EMEUNET
@EMEUNET · X

RT @ARD_BMJ: Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparin…

Jan 2, 2020 · 6 shares · 7,483 followers View post →
Iván Cusácovich
@icusacovich · X

RT @ARD_BMJ: Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparin…

Jan 1, 2020 · 6 shares · 494 followers View post →
Beatrice Goilav, MD
@BGoilav · X

RT @ARD_BMJ: Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparin…

Dec 31, 2019 · 6 shares · 4,722 followers View post →
Griss Valero
@Griss_Valero · X

RT @ARD_BMJ: Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparin…

Dec 31, 2019 · 6 shares · 66 followers View post →
Annals of the Rheumatic Diseases
@eular_ARD · X

Listen to our new podcast from the #ACR2019 with Eric Morand about #Anifrolumab in #SLE - the #TULIP-2 study - whilst preparing for the turn of the year.

Dec 31, 2019 · 11 likes · 6 shares · 13,089 followers View post →
Steve Hajioff
@DrSteveHajioff · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/LgZfvwHsF2

Dec 29, 2019 · 661 followers View post →
Atrévete A Saber
@AtreveteSaber · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 26, 2019 · 27 shares · 12 followers View post →
Stefania Arciello
@StefaniaArciell · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/JcDg87CC1p

Dec 26, 2019 · 1,940 followers View post →
Icro Meattini
@Icro_Meattini · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 26, 2019 · 10 shares · 3,062 followers View post →
md.opinion
@pauhernandez040 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 26, 2019 · 27 shares · 147 followers View post →
I. Pecino MS
@ipecino10 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 26, 2019 · 27 shares · 162 followers View post →
Jacopo Olivieri
@pancho_daz · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 26, 2019 · 10 shares · 41 followers View post →
OncoAlert
@OncoAlert · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 26, 2019 · 10 shares · 40,459 followers View post →
Jorge Rojas Serrano
@jorroser · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 26, 2019 · 27 shares · 3,287 followers View post →
José María Jiménez
@J_M76J · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 5 followers View post →
Franklin Loachamin
@FranLoachamin · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 4,888 followers View post →
Ahmad Masri
@MasriAhmadMD · X

https://t.co/jelgrJ9t0T

Dec 25, 2019 · 1 like · 9,054 followers View post →
Chile717
@Chile7171 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 687 followers View post →
Santiago.
@riseupmen · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 300 followers View post →
Florent Peyraud
@FlorentPeyraud · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 25, 2019 · 10 shares · 310 followers View post →
Félix Balazard
@felbalazard · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 25, 2019 · 10 shares · 687 followers View post →
Philippe Froguel
@philippefroguel · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 25, 2019 · 10 shares · 5,017 followers View post →
Sarah Abou Alaiwi
@sarahaboualaiwi · X

RT @FAndreMD: 18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001),…

Dec 25, 2019 · 10 shares · 2,728 followers View post →
FabriceAndre
@FAndreMD · X

18 years after the discovery that type I interferon is a key molecular target in patients with lupus (Blanco, Science, 2001), a randomized trial shows that Anifrolumab is effective in SLE. A very good illustration of translational science https://t.co/2mXHYHeAtZ

Dec 25, 2019 · 23 likes · 10 shares · 15,267 followers View post →
Conexión Panamericana
@conexionpana · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/ddcp8ZzOcb

Dec 25, 2019 · 142 followers View post →
Djreys
@Djreys2 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 108 followers View post →
Jhon M. Ch.
@Jhon2129hugo · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 144 followers View post →
Hans-Joachim Anders
@hjanders_hans · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 3,072 followers View post →
Soumya Raychaudhuri সৌম্য রায়চৌধুরী
@soumya_boston · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 3,171 followers View post →
Ricardo Bedón
@ricardo_bedon · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 1,508 followers View post →
gabriela salmón
@gabrielasalmon4 · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 375 followers View post →
garaxico
@garaxico · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 32 followers View post →
Dr Jorge L Vázquez C
@DrJorgevazquezC · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 429 followers View post →
Dr Zeeshan Ghias Khan, MBBS, FCPS
@shanoghias · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 421 followers View post →
Wil !!!!
@WilmerMD · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 41 followers View post →
Rebuilding
@CaribeWellness · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 2,069 followers View post →
MZet
@Tezakrim · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 725 followers View post →
Doctor
@yunnnmyisme · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 249 followers View post →
Hugo Rubalcava
@HugoRubalcava · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 260 followers View post →
Pub Health Monitor
@monitor_PH · X

RT @NEJM: Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 27 shares · 1,816 followers View post →
NEJM
@NEJM · X

Original Article: Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/PwZnsYSu2F

Dec 25, 2019 · 54 likes · 27 shares · 931,425 followers View post →
LLZ Consulting
@llzconsulting · X

Trial of Anifrolumab in Active Systemic #Lupus Erythematosus | NEJM https://t.co/EEoGUDMrYb

Dec 22, 2019 · 269 followers View post →
Krishan Maggon
@kkmaggon · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/UFiMNus5hV https://t.co/XdLRrvRbNK

Dec 22, 2019 · 999 followers View post →
Lupus News
@Lupus_bio · X

RT @Lupus_bio: Trial of Anifrolumab in Active Systemic Lupus Erythematosus.: Anifrolumab a human monoclonal antibody to type I interferon r…

Dec 21, 2019 · 1 share · 1,054 followers View post →
the paper link
@the_paper_link · X

Trend new: *Morand EF* et al (N Engl J Med) __Trial of Anifrolumab in Active Systemic Lupus Erythematosus.__ https://t.co/5JVN0RW4XQ

Dec 20, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

Trend up+2: *Morand EF* et al (N Engl J Med) __Trial of Anifrolumab in Active Systemic Lupus Erythematosus.__ https://t.co/5JVN0RW4XQ

Dec 19, 2019 · 136 followers View post →
Paresh Jobanputra
@JobanputraP · X

Hmmmm. Wait & see I guess. Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/RBdI221vII

Dec 19, 2019 · 61 followers View post →
the paper link
@the_paper_link · X

Trend new: *Morand EF* et al (N Engl J Med) __Trial of Anifrolumab in Active Systemic Lupus Erythematosus.__ https://t.co/5JVN0RW4XQ

Dec 19, 2019 · 136 followers View post →
Lupus News
@Lupus_bio · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.: Anifrolumab a human monoclonal antibody to type I interferon receptor subunit 1 investigated for the treatment of systemic lupus erythematosus SLE did not have a significant effect on the… https://t.co/wZnSUA05lk

Dec 19, 2019 · 1 share · 1,054 followers View post →
LuisC FernándezLisón
@drlison · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/zDlq01URxj

Dec 19, 2019 · 4,436 followers View post →
Abdelhamid Hamdy
@abdelhamed012 · X

RT @HofstraKidney: Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t…

Dec 19, 2019 · 4 shares · 3,531 followers View post →
john morley
@drjohnmorley · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/FeDaA5qISM

Dec 19, 2019 · 8,285 followers View post →
Maria T. Carney MD, MACP
@MCarneyMD · X

RT @HofstraKidney: Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t…

Dec 19, 2019 · 4 shares · 2,361 followers View post →
Silvia Suárez
@SilviaPorto88 · X

RT @caminalm: Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/Kj8K36XLFW

Dec 19, 2019 · 1 share · 267 followers View post →
Abdelhamid Hamdy
@abdelhamed012 · X

RT @LuisAlvarezRa: Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/nxiIB9f7kY

Dec 19, 2019 · 1 share · 3,531 followers View post →
minnlab_litbot
@MLitbot · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus. https://t.co/PGz4DTbK1t

Dec 19, 2019 · 71 followers View post →
carlota bernal
@CarlotaBernal · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/kUW4UzlGJJ

Dec 19, 2019 · 467 followers View post →
Luis Enrique Alvarez
@LuisAlvarezRa · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/nxiIB9f7kY

Dec 19, 2019 · 1 like · 1 share · 911 followers View post →
Ana Maria Matias
@AMCMA6 · X

RT @HofstraKidney: Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t…

Dec 19, 2019 · 4 shares · 313 followers View post →
د. سعود أبوحربش Dr.Saud Abu-Harbesh
@SaudAbuHarbesh · X

علاج فعال في حلات الذئبة الحمراء antibody to type I interferon receptor is an effective treatment for SLE Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/Sod1q4wOfm

Dec 19, 2019 · 1 like · 1,050 followers View post →
Kenar Jhaveri
@kdjhaveri · X

RT @HofstraKidney: Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t…

Dec 19, 2019 · 4 shares · 11,777 followers View post →
HofNorthwell Kidney
@HofstraKidney · X

Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://t.co/iCBv3q0ow7

Dec 19, 2019 · 5 likes · 4 shares · 2,936 followers View post →
Hofstra Kidney
@hofstrakidney.bsky.social · Bluesky

Richard Furie from our Rheumatology Division @NEJM Trial of Anifrolumab in Active Systemic Lupus Erythematosus https://www.nejm.org/doi/full/10.1056/NEJMoa1912196#.XftQ7c95Swc.twitter

Dec 19, 2019 View post →
Luis Caminal
@caminalm · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/Kj8K36XLFW

Dec 19, 2019 · 2 likes · 1 share · 967 followers View post →
JUAN GARZA RAMOS
@JUANGARZA13 · X

Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/dRGSUus2xD

Dec 18, 2019 · 298 followers View post →
官澤洋平 YK Hospitalist
@Yohei_Kanzawa · X

マブは追いつけなくなってきました。SLE治療薬、Ⅰ型インターフェロン受容体抗体、アニフロマブ anifromabのRCT。#SLE Trial of Anifrolumab in Active Systemic Lupus Erythematosus | NEJM https://t.co/bAMZr0w2YH

Dec 18, 2019 · 1 like · 1 share · 3,304 followers View post →
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org/doi/full/10.1056/nejmoa1912196)。Biogenのこの新薬は皮膚SLEを標的化したものだが、感染症はインターフェロン抑制薬のクラス有害効果である。 関連する ...

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לופוס זאבת Lupus עמותת עינבר‎. 1563 likes · 4 talking about this. ‎עמותה ישראלית לנפגעים במחלות ראומטיות, אוטואימוניות ודלקתיות וארגון הלופוס הישראלי‎

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The New England Journal of Medicine. December 18, 2019. Doi: 10.1056/NEJMoa1912196. No photo description available. Leonardo Vitor Silva and 26 others ·

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https://doi.org/10.1056/NEJMOA1912196. 14. Liu W, Li M, Wang Z, Wang J. IFN-γ mediates the development of systemic lupus erythematosus ...

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The New England Journal of Medicine. 2020;382(3):211-221. doi:10.1056/NEJMoa1912196.

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org/doi/full/10.1056/nejmoa1912196 19.Furie R, et al. Type I interferon inhibitor anifrolumab in active systemic lupus erythematosus (TULIP ...

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Morand EF et al., NEJM 2020; doi: 10.1056/NEJMoa1912196 · Augustin M et al., Acta Derm Ven 2022; https://doi.org/10.1111/jdv.18168 · Blauvelt A ...

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DOI: 10.1056/NEJMoa1912196. Epub 2019 Dec 18. PMID: 31851795. 3: Koichiro Ohmura (2021) Which is the best SLE activity index for clinical ...

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Мне нравится, что в клинические испытания 3 фазы анифролумаба](https://www.nejm.org/doi/full/10.1056/nejmoa1912196) (Saphnelo) включили ...

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org/doi/full/10.1056/nejmoa1912196. nejm.org. Trial of Anifrolumab in Active Systemic Lupus Erythematosus |. 4 yrs. Recent Posts. Организация на ...

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N Engl J Med, 2020; 382, DOI: 10.1056/NEJMoa1912196. 13.Safety and efficacy of two doses of anifrolumab compared to placebo in adult subjects ...

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The New England Journal of Medicine. 2020;382(3):211-221. doi:10.1056/NEJMoa1912196.

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פירמידת הטיפולים למחלת הזאבת. מאורח חיים בריא ועד IVIG. פרופ' גודארד נותנת לנו סקירת טיפולים עדכנית וגם הצצה לעתיד עם מחקר של תרופה חדשה.

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10 likes, 0 comments - romatoloji.klinigi on January 25, 2020: "Sistemik #lupus Eritematozus kadınlarda tedavisinde yeni bir potansiyel ...

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Abstract BACKGROUND Anifrolumab, a human monoclonal antibody to type I interferon receptor subunit 1 investigated for the treatment of ...

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doi: 10.1056/nejmoa1912196, https://www.nejm.org/doi/full/10.1056/NEJMoa1912196. Currently rated 5.0 by 1 person. Posted in: Medical Research ...

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