New parathyroid function index for the differentiation of primary and secondary hyperparathyroidism: a case-control study.

Yanhong Guo, Qin Wang, Chunyan Lu, Pianpian Fan, Jing Li, Ximing Luo, Decai Chen

January 2020

Synopsis of Social media discussions

The majority of discussions emphasize the promising diagnostic capability of the PFindex, highlighting its potential to improve clinical decision-making, with words like ‘differentiating’ and ‘screening tool’ underscoring its importance. This tone reflects strong support and high engagement with the article's implications for healthcare practice.

A
Agreement
 Strong agreement

Most discussions acknowledge the effectiveness of the new PFindex in distinguishing hyperparathyroidism types, with posts citing cutoff values and clinical relevance.

I
Interest
 High level of interest

Posts show high interest by focusing on specific diagnostic improvements and potential clinical applications, like differentiating NPHPT from VDSHPT.

E
Engagement
 High engagement

Several discussions delve into the methodology and significance, indicating a deep engagement with the research findings.

I
Impact
 Moderate level of impact

The discussions suggest this index could significantly influence clinical diagnostics, though some posts hint at the need for further validation, making the impact somewhat cautious.

Social Mentions

YouTube

1 Videos

Twitter

2 Posts

Metrics

Video Views

4,331

Total Likes

66

Extended Reach

5,452

Social Features

3

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Understanding Parathyroid Disorders and Calcium Homeostasis

Understanding Parathyroid Disorders and Calcium Homeostasis

This presentation covers diseases of the parathyroid glands and calcium balance, including radiation impact on the parathyroid, calcium sensing receptors, and management of primary hyperparathyroidism, providing essential insights into endocrine health.

Johannes W. Dietrich

May 30, 2020

4,331 views

  • Sallie Powell
    @SpSallie (Twitter)

    RT @Aureliano241972: PFindex (PFindex = Ca*PTH/P) > 34 to differentiate #normocalcemic #primary #hyperparathyroidism from #vitaminD deficie…
    view full post

    December 20, 2021

    1

  • Maurizio Merico
    @Aureliano241972 (Twitter)

    PFindex (PFindex = Ca*PTH/P) > 34 to differentiate #normocalcemic #primary #hyperparathyroidism from #vitaminD deficiency-induced secondary hyperparathyroidism https://t.co/edSRtzR79U
    view full post

    January 9, 2020

    2

    1

Abstract Synopsis

  • The study introduced a new parathyroid function index (PFindexCaPTHPBR) to help differentiate primary hyperparathyroidism (PHPT), including its normocalcemic form (NPHPT), from vitamin D deficiency-related secondary hyperparathyroidism (VDSHPT), since these conditions are hard to distinguish based on calcium and PTH levels alone.
  • The research showed that the PFindex was significantly higher in PHPT patients compared to NPHPT, VDSHPT, and healthy controls, with a cutoff value of 34 providing high sensitivity and specificity for diagnosing PHPT and NPHPT.
  • The PFindex demonstrated excellent diagnostic ability, especially in distinguishing NPHPT from VDSHPT, suggesting it could be a useful, simple screening tool in clinical settings to accurately diagnose different hyperparathyroidism conditions.]