If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely advertised), but in all likelihood, both work *reasonably* well in clinical settings & better together. (1/2) https://t.co/Vw5UZH8Jd2
A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression.
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Jan 2020 – Sep 2025Where it's discussed
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X / Twitter91 posts
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News30 articles
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Blogs4 articles
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YouTube3 videos
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Bluesky2 posts
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AI synopsis
What people are saying
The discussions highlight the consensus on the effectiveness of combined treatments for depression, with several users stating things like, 'Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression. Combined is!' This phrasing emphasizes a shared belief in the need for integrated approaches to mental health treatment. The tone across various posts ranges from supportive to critical, with terms such as 'very important study' used frequently, indicating both excitement and the urgency around implementing these findings in practice.
Many discussions exhibit a favorable stance towards the findings of the meta-analysis, indicating a consensus that combined treatment is advantageous.
The posts reflect a high level of curiosity and relevance regarding treatment approaches for depression, showcasing the significance of the research.
While some posts critique aspects of the study, others engage deeply with the findings, citing specific studies and implications for treatment.
Users perceive the findings as having substantial implications for clinical practice and treatment methodologies for depression.
Abstract in brief
- A network meta-analysis was conducted to compare the effects of psychotherapies, pharmacotherapies, and their combination for adult depression treatment, analyzing data from 101 studies involving 11,910 patients.
- The results indicated that combined treatment was more effective than either psychotherapy or pharmacotherapy alone in achieving a significant treatment response and remission rates.
- For patients with moderate to severe depression, the combination approach showed the best outcomes, but further research is needed to assess long-term effects and cost-effectiveness.
Top posts
Most liked on X and BlueskyNew Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with moderate #depression, chronic & treatment refractory states #tolerability & personal choice vital #OpenAccess #WorldPsychiatry https://t.co/H6TjatdDMP https://t.co/YhdsXnBCkc
Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is! — A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/NbqcNlg4K1
Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers https://t.co/IFv0w7IzrS
La terapia tiene mejores resultados en la ansiedad somática que los medicamentos, y viceversa para la ansiedad psíquica/cognitivaen el tratamiento de la #Depresion. #saludmental https://t.co/FODF2HtguS
En revanche l’avantage devant une telle affirmation c’est qu’il suffit de citer une seule étude qui dit le contraire et la formule « l’intégralité de la littérature scientifique » tombe instantanément. Meta-analyse de 101 essais randomisés
All mentions
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@HenryRunamucker 1/evidence Cuijpers, P., Noma, H., Karyotaki, E., Vinkers, C. H., Cipriani, A., & Furukawa, T. A. (2020). A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression. World Psychiatry, 19(1), 92–107.
RT @Hugo_Baup: En revanche l’avantage devant une telle affirmation c’est qu’il suffit de citer une seule étude qui dit le contraire et la f…
En revanche l’avantage devant une telle affirmation c’est qu’il suffit de citer une seule étude qui dit le contraire et la formule « l’intégralité de la littérature scientifique » tombe instantanément. Meta-analyse de 101 essais randomisés
@f_hieronymus Anyway I have nothing against antidepressants being in the guidelines, but I'm against your statements pretending they are definitely better than psychotherapy. An example reference that found no difference between psychotherapy and medications: https://t.co/7WVbh4JTKI
@Psycholosopher their 2020 analysis actually managed to dig up a single DBT study https://t.co/mu8w1J2gqq - I think the quality of evidence for any efficacy is still poor, pill placebo is probably a better control https://t.co/DxhCrKv8rd but the quality of evidence is still poor
RT @Mindbuddy_jp: 中等症以上のうつ病に対する認知行動療法は、薬物療法とほぼ同等の効果を有すること が報告されています。 また、薬物療法と認知行動療法を併用して行うと改善率は上がり、薬物療法単独よりも治療中断率を引き下げることが確認されています。 https:/…
中等症以上のうつ病に対する認知行動療法は、薬物療法とほぼ同等の効果を有すること が報告されています。 また、薬物療法と認知行動療法を併用して行うと改善率は上がり、薬物療法単独よりも治療中断率を引き下げることが確認されています。 https://t.co/8yYChaII8U #うつ病 #認知行動療法
https://t.co/voTBdM7k4I
RT @Mental_Elf: Read the free full text paper in World Psychiatry: https://t.co/4nn2pStRtK #MentalHealthResearchMatters
RT @Mental_Elf: Read the free full text paper in World Psychiatry: https://t.co/4nn2pStRtK #MentalHealthResearchMatters
Read the free full text paper in World Psychiatry: https://t.co/4nn2pStRtK #MentalHealthResearchMatters
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @ElPaido: La terapia tiene mejores resultados en la ansiedad somática que los medicamentos, y viceversa para la ansiedad psíquica/cognit…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @drjohnmorley: A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of ad…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @drjohnmorley: A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of ad…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @ElPaido: La terapia tiene mejores resultados en la ansiedad somática que los medicamentos, y viceversa para la ansiedad psíquica/cognit…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/9NO2GNOK61
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @ElPaido: La terapia tiene mejores resultados en la ansiedad somática que los medicamentos, y viceversa para la ansiedad psíquica/cognit…
La terapia tiene mejores resultados en la ansiedad somática que los medicamentos, y viceversa para la ansiedad psíquica/cognitivaen el tratamiento de la #Depresion. #saludmental https://t.co/FODF2HtguS
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @yasseraddabbagh: Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is!…
RT @drjohnmorley: A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of ad…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/VRut0BEWFa
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @yasseraddabbagh: Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is!…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @yasseraddabbagh: Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is!…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
https://onlinelibrary.wiley.com/doi/full/10.1002/wps.20701#.Yu_88uzDdu0.twitter
Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is! — A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression...
Very important study! Neither psychotherapy nor pharmacotherapy alone is optimal treatment for depression.Combined is! — A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/NbqcNlg4K1
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
RT @awaisaftab: If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely…
If antidepressants are marginally effective in the acute treatment of depression, so are psychotherapies (something rarely advertised), but in all likelihood, both work *reasonably* well in clinical settings & better together. (1/2) https://t.co/Vw5UZH8Jd2
@VeysiCe Buyurun: https://t.co/sEEyqwVxfm
@arcacengiz Kronik depresyonda da ilaçlar psikoterapilerden daha etkili değil. Buyurun: https://t.co/sEEyqwVxfm
@sarurune Table1に含まれる心理療法の種類をご覧ください。 A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/BOXwcrpBBR
@JosAlfo12870753 @AshlaHeartfilia @psidenisa 2020 World Psychiatry https://t.co/LUI2SvzJ49
@EikoFried @HengartnerMP @tkaiser_science @Martin_Ploederl This one from @pimcuijpers and coll might be closer to what you seek (I suspect you already know about it) but only for adult depression : https://t.co/wj6G7udsuZ
RT @psychunseen: THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit o…
RT @psychunseen: THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit o…
RT @psychunseen: THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit o…
RT @psychunseen: THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit o…
RT @psychunseen: THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit o…
THREAD 1/3 Recent meta-analysis (Cuipers 2020) of RCTs comparing antidepressants v. psychotherapy v. combo shows benefit of combo. "The combination of psychotherapy and pharmacotherapy seems to be the best choice for patients with moderate depression." https://t.co/JZp3SDLiNx
Combined drug & #psychological therapies may be most effective 4 treatment of adult depression meta-analysis #psychotherapies #pharmacotherapies https://t.co/EYptTMgGIX @DFrizelle @charley_psych @NigelWainwright
#psychotherapy and ADM seem equally effective but psychotherapy seems more acceptable (=lower dropout). Of note, combination treatment works best, which we didn’t assess https://t.co/RO8YeVI78c 10/25 https://t.co/mIcv3WzhKQ
@AnaAnita83 @jcfuertes @redaccionmedica @diariomedico Le animo, además, a revisar la evidencia científica comparativa más reciente. https://t.co/LUI2SvzJ49
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
RT @MaximeTaquet: Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers…
Antidepressant + Psychotherapy more effective than either alone. A very interesting network meta-analysis by @pimcuijpers https://t.co/IFv0w7IzrS
meta‐analysis: combined treatment was more effective than psychotherapy alone (RR=1.27; 1.14‐1.39) and pharmacotherapy alone (RR=1.25; 1.14‐1.37) in achieving response at the end of treatment in patientes with MDD https://t.co/8yOBdoGByL
A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/YPzLziacW4 https://t.co/Ge8pLqbRuy
In a new meta-analysis of head-to-head trials of meds vs therapy in treatment of depression, therapy delivered significantly better outcomes than meds at 6-month and 12-month follow-ups. https://t.co/fg6ltbqjin
New meta-analysis suggests combining meds + therapy for clinical depression is modestly more effective than either treatment alone. In best metas, meds > placebo by 0.3 SD, similar effects for therapy. In new study, meds+therapy > placebo by 0.43 SD. https://t.co/hAjPr1J74C
La combinación de psicoterapia y farmacoterapia parece ser la mejor opción para los pacientes con depresión moderada. https://t.co/mrArOEdF6C
https://t.co/Jub5F3LWX6
A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression https://t.co/uHvLGiyluO
RT @anpir_org: #Metaanálisis en red: el tratamiento combinado ofrece mejores resultados que los #psicofármacos o la #psicoterapia solas en…
#Metaanálisis en red: el tratamiento combinado ofrece mejores resultados que los #psicofármacos o la #psicoterapia solas en #depresión No encuentran diferencias entre ambas solas en efectividad pero la #psicoterapia es más aceptable. https://t.co/pbIK4pujYK
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: More investment in psychological therapies for #depression is essential. Also ensuring a individualised approach with social,…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: More investment in psychological therapies for #depression is essential. Also ensuring a individualised approach with social,…
More investment in psychological therapies for #depression is essential. Also ensuring a individualised approach with social, psychological & pharmacological interventions based on informed choices. Network MA findings in context #OpenAccess https://t.co/H6TjatdDMP https://t.co/oDT0nq7dCc
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
RT @raj_psyc: New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with mod…
New Network Meta-analysis: Combination of #psychotherapy & #pharmacotherapy seems to be the best choice for patients with moderate #depression, chronic & treatment refractory states #tolerability & personal choice vital #OpenAccess #WorldPsychiatry https://t.co/H6TjatdDMP https://t.co/YhdsXnBCkc