Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_EggLab @LindsayWu_UNSW #IVF https://t.co/xV1sXW6iyz https://t.co/lDgl4dKUK5
NAD Repletion Rescues Female Fertility during Reproductive Aging.
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Feb 2020 – Sep 2025Where it's discussed
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X / Twitter120 posts
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News28 articles
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Blogs9 articles
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YouTube3 videos
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AI synopsis
What people are saying
Several discussions focused on the transformative potential of NAD+ repletion, citing specific effects such as the restoration of oocyte quality and improved fertility rates in aged mice. The tone of excitement is evident as users describe the findings as groundbreaking, using phrases like 'game changer' and 'intriguing evidence', which underscore the article's relevance and the optimism surrounding its implications in reproductive health.
The majority of discussions express strong support for the findings of the publication, highlighting its significance in enhancing understanding of female fertility during aging.
The discussions indicate a high level of curiosity and relevance, with many users expressing eagerness to learn about the implications of NAD+ repletion.
While there are multiple references to the methodologies and findings, not all discussions reflect deep analysis. Some are more surface-level reactions.
Many users articulate the belief that the research holds the potential for substantial impact on fertility treatments and reproductive health.
Abstract in brief
- Female reproductive aging leads to a decline in oocyte quality, which significantly affects fertility.
- Treatment with the NAD precursor nicotinamide mononucleotide (NMN) improves oocyte quality and restores fertility in aged female mammals.
- Additionally, NMN supplementation also benefits embryonic development, indicating that boosting NAD levels in later life could help improve reproductive function in females.
Top posts
Most liked on X and BlueskyNAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternative to ARTs? https://t.co/Su3ihiJn5R via @YouTube
NAD+ Repletion Rescues Female Fertility during Reproductive Aging (2020) https://t.co/zVBZoQyStx @CellReports https://t.co/phQy69vFQ7
Here's a nice review/explainer of our recent paper - big thanks to @EleanorSheekey for your interest and putting this together. NMN and fertility - an alternative to ARTs? https://t.co/txvTHCWOHA via @YouTube
NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC15c
All mentions
Developing Techniques to Reverse Aging and Restore Functionality
Being able to stop and reverse aging is something many strive for. Recent research reveals methods that enhance regenerative capacity and restore youthful epigenetic information in tissues, showing promise in reversing…
Improving Female Fertility with NMN Supplementation
Reproductive aging in female mammals leads to a decline in oocyte quality. This video discusses a recent study showing that NMN, an NAD precursor, enhances oocyte quality and restores fertility in aged mice, presenting…
Impact of Aging on Female Fertility and Oocyte Quality
This video discusses the project by students at Universidade de Aveiro and UNESP, exploring how aging affects ovarian function. The decline in oocyte quality begins between ages 30 and 35, influenced by diet, lifestyle…
@zzirgly
@BrendaN64146511
@mishan41kkk @BioProtocol NAD+ collapse drives aging through multiple pathways, including compromised DNA repair. NMN boosts NAD+ and SIRT2 activity, improving oocyte quality (DOI: 10.1016/j.celrep.2020.01.058). Nicotinamide restores NAD+/NADH ratios and sirtuin signaling in senescent cells (DOI:
@mishan41kkk @BioProtocol NMN boosts NAD+ and activates sirtuins simultaneously - that's the beauty of the system. Evidence shows SIRT2 overexpression mimics many NMN benefits (DOI: 10.1016/j.celrep.2020.01.058), but critically NMN engages both SIRT2-dependent AND independent pathways. The stack could
@Thanhtulhpl01 @BioProtocol @BioavailableNd The evidence is mixed but revealing. NMN reverses oocyte NAD(P)H decline, doubles live births in aged mice, and extends female median lifespan by 8.5% (DOI: 10.1016/j.celrep.2020.01.058, 10.1101/2024.06.21.599604). No HRT study matches these systemic effects. Yet the renal NAD+
RT @LindsayWu_UNSW: Maintaining NAD+ levels can be important during conditions of stress, such as ageing, inflammation and the side effects…
Maintaining NAD+ levels can be important during conditions of stress, such as ageing, inflammation and the side effects of chemotherapy. For example, we showed that restoring NAD+ levels could overcome age-related infertility... https://t.co/FbvJidAuIA
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/W4A6GKRc3J
RT @davidasinclair: NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
RT @davidasinclair: NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
RT @davidasinclair: NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
RT @davidasinclair: NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
RT @davidasinclair: NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
NAD+ Repletion Rescues Female Fertility during Reproductive Aging, led by @LindsayWu_UNSW https://t.co/r8eBAFf2tS
RT @agingdoc1: NAD+ Repletion Rescues Female Fertility during Reproductive Aging (2020) https://t.co/zVBZoQyStx @CellReports https://t.co/…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging (2020) https://t.co/zVBZoQyStx @CellReports https://t.co/phQy69vFQ7
Nature denies it, science reverses it! https://t.co/X6HUOnAZ2J NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/DngVmFq2nO https://t.co/Et66ZMlYOI
@GametoGen @EricVerdin @m__marinova @davidasinclair @jenngarrison NAD boosting may improve oocyte quality via SIRT2/BuBR1 improving spindle formation. https://t.co/fie8hjgBtC
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/0tv8gjO5gn
NMNサプリを飲むと体内でNAD +に変わる。 NAD +は妊娠適齢期にも関係する。 年齢と共に減るNAD +をNMNとして妊娠期を過ぎたマウスに与えた結果、卵子の質が復活し再び妊娠できるようになった。哺乳類全般で同じ可能性大
NAD+ Repletion Rescues Female Fertility during Reproductive Aging - ScienceDirect https://t.co/QhBxqUvOja
Several reports have now provided intriguing evidence that management of mitochondria may hold the key to improving egg quality with age. NAD+ Repletion Rescues Female Fertility during Reproductive Aging: Cell Reports https://t.co/Xv9yvMz0I1
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging: Cell Reports https://t.co/Dzgtd4wmpd
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @FertilityCnxn: Loss of oocyte quality with age accompanies declining levels of metabolic cofactor NAD+. Treatment with NAD+ metabolic p…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
Loss of oocyte quality with age accompanies declining levels of metabolic cofactor NAD+. Treatment with NAD+ metabolic precursor nicotinamide mononucleotide (NMN) rejuvenates oocyte quality in aged animals, leading to restoration in fertility. https://t.co/vwJhbe8CKh
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @CellReports: NAD+ repletion rescues female fertility during reproductive aging https://t.co/aJAS8uhdeY
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @CellReports: NAD+ repletion rescues female fertility during reproductive aging https://t.co/aJAS8uhdeY
NAD+ repletion rescues female fertility during reproductive aging https://t.co/aJAS8uhdeY
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @RG_EggLab: Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternati…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_EggLab @LindsayWu_UNSW #IVF https://t.co/jNgCaiwLTJ …https://t.co/5G3xSli2Xn … https://t.co/VYpgeuaSYs
RT @davidasinclair: Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_…
Cool animation of our collaboration’s findings how NMN reverses female reproductive age. An honor to work with you @RG_EggLab @LindsayWu_UNSW #IVF https://t.co/xV1sXW6iyz https://t.co/lDgl4dKUK5
Nice summary of our recent paper from @UNSWMedicine in @CellReports on reproductive ageing. NMN and fertility - an alternative to ARTs? https://t.co/Su3ihiJn5R via @YouTube
RT @LindsayWu_UNSW: Here's a nice review/explainer of our recent paper - big thanks to @EleanorSheekey for your interest and putting this t…
RT @LindsayWu_UNSW: Here's a nice review/explainer of our recent paper - big thanks to @EleanorSheekey for your interest and putting this t…
RT @EleanorSheekey: This week I cover the recent paper by the labs of @DrM_Bertoldo @LindsayWu_UNSW and @davidasinclair ; NMN and fertility…
RT @EleanorSheekey: This week I cover the recent paper by the labs of @DrM_Bertoldo @LindsayWu_UNSW and @davidasinclair ; NMN and fertility…
Here's a nice review/explainer of our recent paper - big thanks to @EleanorSheekey for your interest and putting this together. NMN and fertility - an alternative to ARTs? https://t.co/txvTHCWOHA via @YouTube
RT @EleanorSheekey: This week I cover the recent paper by the labs of @DrM_Bertoldo @LindsayWu_UNSW and @davidasinclair ; NMN and fertility…
This week I cover the recent paper by the labs of @DrM_Bertoldo @LindsayWu_UNSW and @davidasinclair ; NMN and fertility - an alternative to ARTs? https://t.co/JcVEo7BjlT via @YouTube #fertility #biochemistry #scicomm
RT @CooNomon: NMNが加齢に伴う繁殖能力、卵母細胞の質の低下を改善することがマウスで確認されました。人工授精の年齢も高齢化している中で、NMNを補充することで、自分の卵子の質を上げる可能性があるかもしれません。 https://t.co/yZLt5bu31Q #L…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/20CZTFSpgw
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/MbcNuHAAg0
RT @nhmrc: Lifting fertility rates in older female mice. Researchers at @UQ_news & @UNSW are using a metabolic compound that reverses agein…
#Scientoon on "Scientists can reverse the reproductive ageing in female mice" published in #cellreports by DrM_Bertoldo & team. Feel free to share under creative commons Link: NAD Repletion Rescues Female Fertility during Reproductive Aging #sciart #sc…https://t.co/6zEr64VbY9
Lifting fertility rates in older female mice. Researchers at @UQ_news & @UNSW are using a metabolic compound that reverses ageing in eggs. @ProfHaydenHomer says the work might point to solutions for older women struggling to conceive. @nhmrc @CellReports https://t.co/fkSVMtgKal https://t.co/y1qEPEh2XG
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/EvWrLhUPke
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
NMNが加齢に伴う繁殖能力、卵母細胞の質の低下を改善することがマウスで確認されました。人工授精の年齢も高齢化している中で、NMNを補充することで、自分の卵子の質を上げる可能性があるかもしれません。 https://t.co/yZLt5bu31Q #LifeisLong. #NMN #プロダクティブ・エイジング
RT @_atanas_: NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC1…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging (open access, study in mice) #nutrition #diet #women #VitaminB3
Exciting #Discovery #Research @CellReports NAD Repletion Rescues Female Fertility during Reproductive Aging ➡️declining oocyte quality rate-limiting factor fr #fertility ➡️NAD+ metabolic precursor NMN Rx rejuvenates oocyte quality in aged animals https://t.co/ElSCELpJDX https://t.co/wy7Hq2HnJ3
RT @_atanas_: NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC1…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging. https://t.co/fiPGfrLr02
RT @_atanas_: NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC1…
RT @_atanas_: NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC1…
RT @_atanas_: NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC1…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging #NAD #Fertility #ReproductiveAging https://t.co/J9sdVyC15c
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
Recommended by https://t.co/X6HUOniPOB, you may visit this site to find Bio-Medical ideas that aid in identifying pharmaceutical targets, and writing up grant appns. https://t.co/XqRzUPaLn8 https://t.co/mrA0WpPzSa
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @PaulHumpa: Interesting new work! NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/oJs31BeOTV
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @DRKAMALAYOUB: استطاع باحثين اعادة تنشيط الاباضة عند اناث الفئران المتقدمة في السن عن طريق اعطائها مركب ال NAD+ https://t.co/kRU45ptYUr
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/swRjjZsk6D
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/6rbOVswsXr
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @DRKAMALAYOUB: استطاع باحثين اعادة تنشيط الاباضة عند اناث الفئران المتقدمة في السن عن طريق اعطائها مركب ال NAD+ https://t.co/kRU45ptYUr
RT @DRKAMALAYOUB: استطاع باحثين اعادة تنشيط الاباضة عند اناث الفئران المتقدمة في السن عن طريق اعطائها مركب ال NAD+ https://t.co/kRU45ptYUr
استطاع باحثين اعادة تنشيط الاباضة عند اناث الفئران المتقدمة في السن عن طريق اعطائها مركب ال NAD+ https://t.co/kRU45ptYUr
NAD+ Repletion Rescues Female Fertility during Reproductive Aging: Cell Reports https://t.co/XuLS6bYOmc
Interesting new work! NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://t.co/oJs31BeOTV
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…
RT @LindsayWu_UNSW: It's finally out! Please enjoy our new paper on female infertility and reproductive ageing, we hope it will be an impor…