All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. https://t.co/a2DjAUOjuU
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases.
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Feb 2020 – Aug 2025Where it's discussed
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What people are saying
The discussions reflect widespread agreement with the article's hypothesis linking gut health and systemic diseases, often emphasizing Fasano's work and concepts like the microbiome and leaky gut. The tone and language, such as calling Fasano's research 'huge' or 'game-changer,' indicate strong enthusiasm and recognition of the research's significance, suggesting this topic is viewed as having substantial implications for medicine and health.
Most discussions strongly support the article's premise, emphasizing the key role of gut permeability in various diseases.
The topic sparks substantial interest due to its relevance to chronic inflammatory conditions and microbiome research.
Posts reference specific researchers like Fasano, discuss mechanisms such as zonulin's role, and cite large study counts, demonstrating deep engagement.
Numerous discussions highlight the perceived importance of this research for understanding and potentially treating a range of diseases, indicating high impact.
Abstract in brief
- The text explains that many chronic inflammatory diseases (CIDs) may originate from increased gut permeability, often caused by a protein called zonulin, which makes the gut "leaky."
- It highlights how improved hygiene and lifestyle changes have reduced exposure to microorganisms, leading to alterations in gut microbiota and immune system balance, possibly contributing to CIDs — a concept linked to the hygiene hypothesis.
- Recent research emphasizes the importance of genetic factors, gut microbiome, and proteins like zonulin in maintaining gut barrier function, suggesting that targeting gut permeability could lead to new treatments for various CIDs.]
Top posts
Most liked on X and BlueskyAll disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/1ckWT37TYC
10,198+ reads of Alessio Fasano, MD's @F1000Research article re: the role of #zonulin-mediated gut permeability (leaky gut) in pathogenesis of some chronic #inflammatory diseases. @gacd_media @mghfc @harvardmed @MGH_GI @SSCDCeliac Total reads: 56,834 → https://t.co/EaYFo83GeO https://t.co/qNva3w8sLl
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/SCeEgFKyIv
Toda enfermedad comienza ⚠️ en el intestino (permeable): papel de la permeabilidad intestinal mediada por
Todas las patologías empiezan en el intestino, y en parte pueden empezar por una disbiosis. https://t.co/EHX2gfF7pS https://t.co/OvlMnB8PD8
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RT @keisuke4713: 腸の健康が病気にどのように影響するかhttps://t.co/nnEAfpeVRV 病気は腸から始まる ADHD、自閉症、学習障害、肥満、糖尿病、パーキンソン病は、腸内細菌叢の影響を受ける 慢性炎症性疾患(CID)の病因:ゾヌリンを介した腸の…
@ejustin46 This is huge. The entire gut/brain axis (in fact microbiome/everything axis!) is so incredibly important. Celiac disease research on leaky gut/recovery has a big tie in, as well. Alessio Fasano is (finally) getting it! https://t.co/6QeFS2WsuJ
「衛生状態の改善により、微生物への曝露が減少することが、先進国における慢性炎症性疾患の最近の流行の原因の 1 つとして考えられています」 All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic ... https://t.co/tuJS5wTOt7
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/d3AI49yAGB
I really love this article (and its title): "All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases" https://t.co/RuBPxeNSZc https://t.co/od14uYBfZP
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/ZhRm1F1RTv
https://t.co/LMsppbxWzu hemen artikulua osorik
@JaquesTowaki1 @mrc314 Fasano, A. 2020. “All Disease Begins in the (Leaky) Gut: Role of Zonulin-Mediated Gut Permeability in the Pathogenesis of Some Chronic Inflammatory Diseases.” F1000Res. doi:gjw46h https://t.co/NBWf8L2VXz Fasano, A. 2011. https://t.co/KdednPs4OY
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
https://t.co/hn2UibrgmU
RT @observadora007: Toda enfermedad comienza ⚠️ en el intestino (permeable): papel de la permeabilidad intestinal mediada por
Toda enfermedad comienza ⚠️ en el intestino (permeable): papel de la permeabilidad intestinal mediada por
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @CeliacResearch: 10,198+ reads of Alessio Fasano, MD's @F1000Research article re: the role of #zonulin-mediated gut permeability (leaky…
RT @CeliacResearch: 10,198+ reads of Alessio Fasano, MD's @F1000Research article re: the role of #zonulin-mediated gut permeability (leaky…
RT @CeliacResearch: 10,198+ reads of Alessio Fasano, MD's @F1000Research article re: the role of #zonulin-mediated gut permeability (leaky…
10,198+ reads of Alessio Fasano, MD's @F1000Research article re: the role of #zonulin-mediated gut permeability (leaky gut) in pathogenesis of some chronic #inflammatory diseases. @gacd_media @mghfc @harvardmed @MGH_GI @SSCDCeliac Total reads: 56,834 → https://t.co/EaYFo83GeO https://t.co/qNva3w8sLl
Todas las patologías empiezan en el intestino, y en parte pueden empezar por una disbiosis. https://t.co/EHX2gfF7pS https://t.co/OvlMnB8PD8
RT @keisuke4713: 腸の健康が病気にどのように影響するかhttps://t.co/nnEAfpeVRV 病気は腸から始まる ADHD、自閉症、学習障害、肥満、糖尿病、パーキンソン病は、腸内細菌叢の影響を受ける 慢性炎症性疾患(CID)の病因:ゾヌリンを介した腸の…
https://t.co/orY7Sd0H7K https://t.co/bCZez3HeOC
RT @contrariansmind: All disease begins in the (leaky) gut: role of zonulin-mediated.... Fasano A, published by @F1000Research, https://t.c…
All disease begins in the (leaky) gut: role of zonulin-mediated.... Fasano A, published by @F1000Research, https://t.co/s6ThK0tHw6
腸の健康が病気にどのように影響するかhttps://t.co/nnEAfpeVRV 病気は腸から始まる ADHD、自閉症、学習障害、肥満、糖尿病、パーキンソン病は、腸内細菌叢の影響を受ける 慢性炎症性疾患(CID)の病因:ゾヌリンを介した腸の透過性 https://t.co/qkDLvqQ6OB
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/ETHym2KZWj
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
@TuckerGoodrich Fasano: "These studies show that leaky gut plays a central role in chronic inflammation." Paleomedicina: "Our interventions reverse intestinal permeability as well as chronic inflammation." This guy: "Fake news!" https://t.co/yRbkvOLAgK
@kaveh_rashidi @c_ar0lin3 Du har åpenbart ikke peiling på dette. Dr. Alessio Fasano, en pioner innen cøliaki og gluten forskning skriver: "All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases" https://t.co/vXRv1Jy2BE
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
https://t.co/tiS3ETIrBQ
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
@Ancestral_Fit @Mangan150 https://t.co/Lbj4JSCbEL
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/7kUp9CyFaS
RT @juliannejtaylor: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic i…
@Piers_Corbyn From the old medical worldview, we can see a new one emerging: https://t.co/rMkzZzrQp0 https://t.co/wSUgCZ489U
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
All disease begins in the (leaky) gut: role of zonulin-mediated.... Fasano A, published by @F1000Research, https://t.co/LAaMtJ08sQ
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/OHSNzxbsIv
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @controscience: "a major surge of [chronic inflammatory diseases] during the past four decades in the Western hemisphere coincident w th…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @controscience: "a major surge of [chronic inflammatory diseases] during the past four decades in the Western hemisphere coincident w th…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
@cleiton_libardi https://t.co/IANqMgxG4D
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. https://t.co/WlrOatkU7y https://t.co/EIovpizwb0
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @Mangan150: All disease begins in the (leaky) gut An increasingly convincing hypothesis. LPS from gut bacteria promote inflammation and…
RT @juliannejtaylor: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic i…
RT @juliannejtaylor: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic i…
RT @juliannejtaylor: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic i…
RT @juliannejtaylor: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic i…
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/1ckWT37TYC
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/kPHaK6jGKU
RT @BANTonline: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflam…
RT @BANTonline: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflam…
RT @BANTonline: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflam…
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases https://t.co/SCeEgFKyIv
Trend new: *Fasano A* (F1000Res) __All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases__ https://t.co/k4DBAzCb7X
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. https://t.co/NcCboXSGuf
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammat... - Fasano A - https://t.co/u7gwY6JFNR #microbiome
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
RT @Psychobiotic: All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic infl…
All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. https://t.co/a2DjAUOjuU
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