J Headache Pain February 2020 PMID 32054443

Gut-brain Axis and migraine headache: a comprehensive review.

Mahsa Arzani, Soodeh Razeghi Jahromi, Zeinab Ghorbani, Fahimeh Vahabizad, Paolo Martelletti, Amir Ghaemi, Simona Sacco, Mansoureh Togha

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Mentions

Peak: 32 in Feb 2020

across 7 sources since Feb 2020

Extended reach

179,458

potential audience

Total likes

279

Video views

7,971

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Feb 2020 – Sep 2025

Where it's discussed

X / Twitter55 posts
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Facebook12 posts
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AI synopsis

What people are saying

Several posts express support for the connection between gut health and migraines, citing scientific reviews and personal success stories like the resolution of headaches after FMT. The tone balances scientific references with anecdotal evidence, demonstrating active engagement and belief in the significance of the gut-brain interaction in migraine management.

AgreementModerate agreement

Most discussions support the idea that the gut-brain axis influences migraines, with some mentions of known relationships and clinical observations.

InterestHigh interest

Participants show a high level of interest by referencing multiple studies, personal experiences, and potential dietary solutions.

EngagementModerate engagement

The discussions include citing scientific articles, emphasizing the importance of gut health, and sharing anecdotal evidence, indicating moderate to deep engagement.

ImpactModerate impact

The discussions highlight the potential of targeting gut health as a way to manage migraines, suggesting a meaningful impact on treatment approaches.

Abstract in brief

The gutbrain axis refers to the two-way communication between the gastrointestinal (GI) system and the central nervous system (CNS), with research linking migraines to GI disorders like Helicobacter pylori infection, irritable bowel syndrome (IBS), and celiac disease (CD).
The interaction between the gut and brain in migraine patients is influenced by various factors such as inflammatory mediators, gut microbiota, neuropeptides, stress hormones, and nutritional substances, but the exact mechanisms are still not fully understood.
Managing gut health—through bacterial eradication, dietary changes like gluten-free diets, or targeting the gut microbiota—may potentially reduce migraine frequency and severity, especially in patients with associated GI conditions.]

Read the full abstract

All mentions

Understanding Migraines: Triggers, Effects, and Management Strategies

Dr. DawnElise Snipes discusses the triggers and effects of migraines, offering valuable tips for managing this condition. She is an expert in mental health counseling with international training experience. This video…

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Understanding the Gut-Migraine Connection and Solutions

The Gut-Migraine Brain axis is well-established, with numerous studies highlighting how gut health affects migraine severity. By enhancing gut health through diet and probiotics, significant improvements in migraine…

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Exploring Migraine, Neuroinflammation, and Toxoplasma Gondii

This video delves into the connections between migraine, neuroinflammation, and Toxoplasma Gondii. It discusses the role of natural remedies derived from plants and their efficacy against underappreciated microbes…

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Chris Edwards

@ChrisEd16512812 · X

@drkeithsiau There is a well established causal connection between liver gut and brain gut axes , heal and prevent not treat and mask surely? https://t.co/kBGDZRwCam.

Sep 23, 2025 · 1 like · 1,430 followers View post →

UltimApe

@ultimape · X

@OfMikeAndMen I stopped getting cluster headaches after an FMT. It is highly likely gut health could be the deciding factor. https://t.co/YhyFWGMur7

Jun 17, 2025 · 1 like · 6,454 followers View post →

IDREES R CHOWDRY

@idreesaashna · X

@Rasiqdar08 This is known as Gut-Brain axis relationship and people with IBS, celiac disease and even dyspepsia do have headache. https://t.co/7vGprLlzO0

Mar 26, 2024 · 4 likes · 115 followers View post →

EMHA- European Migraine and Headache Alliance

@EMHAlliance · X

Remember to always follow your healthcare professional advice, as each patient has their own individual way of experiencing migraine. Source: https://t.co/tLAgfI6ONr #GutAndBrain #MigraineComorbidities #HeadacheAndDiet https://t.co/7XcRtmRnok

Oct 27, 2023 · 2 likes · 2,447 followers View post →

peter dingle

@drpeterdingle · X

Up to 20% of the population have migraines and it is now considered the most debilitating condition for the under 50’s. We now know that many factors that contribute to migraines come from the gut. And there are simple solutions The Gut Migraine Solution. https://t.co/FKhha4WXtT

Oct 24, 2023 · 1 like · 35 followers View post →

Natalia Velázquez.

@holisticament · X

Relación del eje intestino-cerebro y su ingluencia en los episodios de #migraña: https://t.co/cinQjFW01Y #braingutaxis

Oct 19, 2023 · 1 like · 2,958 followers View post →

Nicholas (@ultimape) Perry

@ultimape.bsky.wovensoup.com · Bluesky

Muh gut brain axis. https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-020-1078-9

Oct 2, 2023 · 1 share View post →

Elena RuizdelaTorre

@ElenaEMHA · X

RT @EMHAlliance: Several factors, such as the gut microbiota profile, neuropeptides, the serotonin pathway, stress hormones and nutritional…

Aug 15, 2023 · 1 share · 214 followers View post →

Di_St

@dstev9534 · X

RT @EMHAlliance: However, further research is needed to fully understand the complexities of how the gut and brain influence migraine episo…

Aug 14, 2023 · 1 share · 253 followers View post →

EMHA- European Migraine and Headache Alliance

@EMHAlliance · X

Aug 14, 2023 · 5 likes · 1 share · 2,447 followers View post →

EMHA- European Migraine and Headache Alliance

@EMHAlliance · X

Several factors, such as the gut microbiota profile, neuropeptides, the serotonin pathway, stress hormones and nutritional substances, appear to influence this connection. Source: https://t.co/5SHDW77Dmi #GutAndBrain #Migraine #MigraineDiet #MigraineComorbidities https://t.co/039ucjZFIR

Aug 14, 2023 · 2 likes · 1 share · 2,447 followers View post →

EMHA- European Migraine and Headache Alliance

@EMHAlliance · X

There is growing evidence that the gut-brain axis plays a role in migraine, although the exact mechanism of this interaction remains unclear. Source: https://t.co/5SHDW77Dmi #GutAndBrain #Migraine #MigraineDiet #MigraineComorbidities https://t.co/k5u1W985kI

Aug 14, 2023 · 1 like · 2,447 followers View post →

Virgil Rucsandescu

@vrucsandescu · X

https://t.co/x2h8pOPGr1

Apr 18, 2023 · 112 followers View post →

αпiпδιтα

@_SyncreticWorld · X

The terminology “gut-brain axis “points out a bidirectional relationship between the GI system and the central nervous system (CNS). https://t.co/HW0zk3WK21

Jul 3, 2022 · 1 like · 15,576 followers View post →

Tinyphantazma

@tinyphantazma · X

@KissAnneEspoo @VPaljakka @rouvaBuick Heti tuli tämä vastaan. https://t.co/rVeJAFmfpL

Jun 13, 2022 · 1 like · 2,625 followers View post →

@NL_Wetenschap

@NL_Wetenschap · X

@Hoesen_OK @mirjam_bloem @radboudumc_weet Even opgezocht: migraine komt blijkbaar vaker voor bij prikkelbare darm syndroom en coeliakie en vice versa. Qua microbioom&migraine lijkt niet veel data te zijn, vaker kijkt men dan naar klinische uitkomst v/e dieet: wel/niet minder hoofdpijn? zie:https://t.co/0rrs1EbpdF

Nov 8, 2021 · 19,217 followers View post →

Crazy Druid

@CraigVecellio · X

@the_scotsman_ @AbsoluteKaty @US_FDA As for migraines, you might need probiotics rather than antibiotics. Consult with your doctor. https://t.co/ssfFe4UjtA

Sep 8, 2021 · 1,027 followers View post →

AJ Beach

@aj_beach_ · X

RT @Upledger_Inst: Gut-brain Axis and migraine headache: a comprehensive review article discusses the direct and indirect evidence suggesti…

Jul 27, 2021 · 1 share · 259 followers View post →

Upledger Institute

@Upledger_Inst · X

Gut-brain Axis and migraine headache: a comprehensive review article discusses the direct and indirect evidence suggesting relationships between migraine and the gut-brain axis. Read More: https://t.co/zWsifC9FcG or go to https://t.co/V6cSLROrW1 Searchable Article Database. https://t.co/QYWwdxGYES

Jul 27, 2021 · 1 like · 1 share · 1,219 followers View post →

William

@WillieWwilliam · X

Like this https://t.co/mjhWkREfG6 A healthy microbiome should be considered as a preventative treatment for migraines

Mar 3, 2021 · 238 followers View post →

Dr. Shawn Thistle

@DrShawnThistle · X

"Gut-brain Axis and migraine headache: a comprehensive review" (Journal of Headache and Pain - open access) Interesting read... Check it out: https://t.co/jJM764YVmz https://t.co/v4HxWO73nT

Mar 30, 2020 · 2 likes · 1,873 followers View post →

Angela Atkins

@angelacatkins · X

Researchers believe that migraine headaches can be improved by diets that support healthy gut microbiota and gut-brain axis. https://t.co/1Jhg8Fd4Jp https://t.co/IYZob4RmtM

Mar 23, 2020 · 206 followers View post →

MedClub

@MedClubPage · X

Arzani M, et al. Gut-brain Axis and migraine headache: a comprehensive review. The Journal of Headache and Pain. 2020; 21:15 https://t.co/wXA3KFGfCP

Mar 9, 2020 · 35,174 followers View post →

SWOO

@swooOsteopathie · X

https://t.co/arMytP3rRG

Mar 5, 2020 · 73 followers View post →

Mastopedia

@mastopedia · X

Gut-brain Axis and migraine headache: a comprehensive review https://t.co/lYXSgBLMvE

Feb 20, 2020 · 537 followers View post →

Bioseutica

@Bioseutica · X

https://t.co/v7ZQwu6NzG #Gut #brain Axis and #migraine #headache: a comprehensive review #microbiome #IBS #IBD #GI #CNS https://t.co/YTDDzrLvc9

Feb 20, 2020 · 1,357 followers View post →

Veena Srivastava

@vkefir · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 20, 2020 · 11 shares · 38 followers View post →

Annie Rippingale

@AnnieRippingale · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 20, 2020 · 11 shares · 7 followers View post →

Cecilia Giron

@mceciliagiron · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 20, 2020 · 11 shares · 310 followers View post →

Salesianos Argentina

@salesianoarg1 · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 19, 2020 · 11 shares · 605 followers View post →

Diana

@PharmphoodTM · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 19, 2020 · 11 shares · 556 followers View post →

susi

@susi38532167 · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 19, 2020 · 11 shares · 450 followers View post →

Bill Sullivan

@wjsullivan · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 18, 2020 · 11 shares · 4,857 followers View post →

Let Us Communicate - Independent SEND Support Grp

@LUC_autism · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 18, 2020 · 11 shares · 3,108 followers View post →

Eros

@ErosSowinski · X

RT @Psychobiotic: Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68…

Feb 18, 2020 · 11 shares · 531 followers View post →

Scott Anderson

@Psychobiotic · X

Gut-brain Axis and migraine headache: a comprehensive review. How does the microbiota affect migraines? https://t.co/68Z6dZz5ZN

Feb 18, 2020 · 19 likes · 11 shares · 18,565 followers View post →

Kate Grimsrud, MD

@KateGrimsrud · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 17, 2020 · 11 shares · 397 followers View post →

Vishal Mehta

@docvishalmehta · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 156 followers View post →

Thiago Dias Sarti

@dias_sarti · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 470 followers View post →

PACT - Primary care Academic CollaboraTive

@GPPACT · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 2,594 followers View post →

Emma Wray

@emwr4y · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 87 followers View post →

Bas Daalmans

@DaalmansBas · X

RT @ChristophBurch: Gut-brain Axis and migraine headache: a comprehensive review Arzani et al. J Headache Pain. 2020 https://t.co/PVQssgp7…

Feb 16, 2020 · 4 shares · 50 followers View post →

Dr. Steven Herzog

@mymigrainedoc · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 960 followers View post →

David Watson

@davidpbwatson · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 74 followers View post →

Palmiro Torrieri jr

@PalmiroJr · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 516 followers View post →

Pia

@MoretoreadO · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 656 followers View post →

Katy Munro

@KatyMunro1 · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 4,626 followers View post →

Simona Sacco

@Simona_Sacco_ · X

RT @headacheNI: Migraine is not just a headache. Association w GI disorders including H Pylori infection, IBD, Coeliac Disease. V though…

Feb 16, 2020 · 11 shares · 1,540 followers View post →

Armando Ribeiro

@Armando_Ribeiro · X

RT @ChristophBurch: Gut-brain Axis and migraine headache: a comprehensive review Arzani et al. J Headache Pain. 2020 https://t.co/PVQssgp7…

Feb 15, 2020 · 4 shares · 5,050 followers View post →

Christian Jiménez Arranz

@arranz_jimenez · X

RT @ChristophBurch: Gut-brain Axis and migraine headache: a comprehensive review Arzani et al. J Headache Pain. 2020 https://t.co/PVQssgp7…

Feb 15, 2020 · 4 shares · 437 followers View post →

Christoph Burch

@ChristophBurch · X

Gut-brain Axis and migraine headache: a comprehensive review Arzani et al. J Headache Pain. 2020 https://t.co/PVQssgp7QM https://t.co/lbWrDM1lOv

Feb 15, 2020 · 13 likes · 4 shares · 15,092 followers View post →

BDA Yorkshire Branch

@BDAyorkshire · X

RT @trott_nick: Review of Gut-Brain Axis & Migraine Headache. "Mechanisms how the gut & the brain interact in pts with migraine - not clea…

Feb 15, 2020 · 4 shares · 1,652 followers View post →

Nick Trott

@trott_nick · X

Feb 15, 2020 · 14 likes · 4 shares · 3,366 followers View post →

Symbiosis papers

@Symbiosispapers · X

Gut-brain Axis and migraine headache: a comprehensive review. https://t.co/CJ20TA2BHk

Feb 15, 2020 · 1,113 followers View post →

Paolo Martelletti

@P_Martelletti · X

RT @NeuroPsychBMC: Gut-brain Axis and migraine headache: a comprehensive review https://t.co/s3YCQy4Mq2

Feb 13, 2020 · 1 share · 770 followers View post →

NeuroPsychBMC

@NeuroPsychBMC · X

Gut-brain Axis and migraine headache: a comprehensive review https://t.co/s3YCQy4Mq2

Feb 13, 2020 · 5 likes · 1 share · 1,587 followers View post →

Gut-brain Axis and migraine headache: a comprehensive review.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding Migraines: Triggers, Effects, and Management Strategies

Understanding the Gut-Migraine Connection and Solutions

Exploring Migraine, Neuroinflammation, and Toxoplasma Gondii