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ACS Nano March 2020 PMID 32069037

Intracellular Nanomaterial Delivery Spiral Hydroporation.

GeoumYoung Kang, Daniel W Carlson, Tae Ho Kang, Seungki Lee, Simon J Haward, Inhee Choi, Amy Q Shen, Aram J Chung

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Mentions

37
Peak: 10 in Feb 2020
across 5 sources since Feb 2020

Extended reach

25,744
potential audience

Total likes

27

Video views

200

Mentions per month

Feb 2020 – Feb 2021

Where it's discussed

  • X / Twitter18 posts
  • News8 articles
  • YouTube7 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The social discussions demonstrate enthusiasm for the spiral hydroporation technique, with posts describing it as a fast, reliable, and less toxic way to deliver nanomaterials into cells. Words like 'effective,' 'high throughput,' and 'breaking cell membranes' signal positive reception and recognition of its transformative potential in nanomedicine and cell biology research.

AgreementModerate agreement

Most discussions highlight the innovative aspects of the spiral hydroporation method, emphasizing its efficiency and potential for drug delivery, indicating broad support.

InterestHigh interest

The discussions show high interest, with posts referencing the method’s speed, high throughput, and versatility, suggesting strong engagement with cutting-edge nanobiotechnology.

EngagementModerate engagement

Many posts cite specific features like high efficiency and minimal toxicity, indicating active engagement and curiosity about the technique.

ImpactHigh impact

Several comments point to the method’s potential to revolutionize intracellular delivery and cell biology applications, reflecting a perception of high impact in the field.

Abstract in brief

  • This study introduces the spiral hydroporator, a new method for delivering nanomaterials into cells by utilizing vortex-induced cell deformation, which temporarily opens up cell membranes without needing carriers or external devices.
  • The platform is versatile and efficient, capable of delivering various nanomaterials like gold nanoparticles, silica nanoparticles, and mRNA into different cell types with up to 96.5% efficiency, high throughput (up to 10 cells per minute), and minimal impact on cell viability (up to 94%).
  • Unlike traditional methods, spiral hydroporation offers a fast (about 1 minute), reliable, and less toxic way to introduce materials into cells, making it a promising tool for advanced cell biology and nanomedicine applications.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Aram Chung
@ac467 · X

Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 18, 2020 · 12 likes · 4 shares · 243 followers View post →
Micro/Bio/Nanofluidics Unit
@ShenU_OIST · X

Drug delivery using microfluidic hydroporation! https://t.co/wDkBR2Ulj1

Feb 23, 2021 · 5 likes · 1 share · 798 followers View post →
Bioconjugate Chem
@BioconjChem · X

New #nanomaterial for #targeting and #drug #delivery: #spiral #hydroporator. Breaking #cell #membrane to deliver #cargo directly inside cells possible for #nanoparticles from 2 to 200nm! High efficiency, throughput, speed rate, and cell viability. @acsnano https://t.co/hqFfACtHo7 https://t.co/SJxhO5irnr

Feb 28, 2020 · 3 likes · 3 shares · 4,008 followers View post →
CD Bioparticles
@CdBioparicels · X

Recently, researchers have developed a fast and effective delivery method for nanomaterials, which uses the force of tiny fluid vortices to deform cell membranes. Learn more: https://t.co/DdoXmBkMKd https://t.co/ysurs1sv0r

Jul 28, 2020 · 1 like · 1 share · 34 followers View post →
Microfluidics Recap
@ufluidicsRecap · X

From @ac467 Chung lab at #koreauniversity. Inertial #microfluidics with a cross-junction producing spiral vortex and T-junction for double cell deformations. Very useful for high-throughput intracellular delivery. @acsnano https://t.co/feQJyQZfPI https://t.co/1gVQw3KSQ0

Jun 20, 2020 · 1 like · 1 share · 32 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @ac467: Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 18, 2020 · 4 shares · 2,588 followers View post →

All mentions

Gary Beane
@pollinus66 · X

RT @ShenU_OIST: Drug delivery using microfluidic hydroporation! https://t.co/wDkBR2Ulj1

Feb 23, 2021 · 1 share · 2,025 followers View post →
Micro/Bio/Nanofluidics Unit
@ShenU_OIST · X

Drug delivery using microfluidic hydroporation! https://t.co/wDkBR2Ulj1

Feb 23, 2021 · 5 likes · 1 share · 798 followers View post →
Gary Beane
@pollinus66 · X

RT @CdBioparicels: Recently, researchers have developed a fast and effective delivery method for nanomaterials, which uses the force of tin…

Jul 28, 2020 · 1 share · 2,025 followers View post →
CD Bioparticles
@CdBioparicels · X

Recently, researchers have developed a fast and effective delivery method for nanomaterials, which uses the force of tiny fluid vortices to deform cell membranes. Learn more: https://t.co/DdoXmBkMKd https://t.co/ysurs1sv0r

Jul 28, 2020 · 1 like · 1 share · 34 followers View post →
Gary Beane
@pollinus66 · X

RT @ufluidicsRecap: From @ac467 Chung lab at #koreauniversity. Inertial #microfluidics with a cross-junction producing spiral vortex and T-…

Jun 20, 2020 · 1 share · 2,025 followers View post →
Microfluidics Recap
@ufluidicsRecap · X

From @ac467 Chung lab at #koreauniversity. Inertial #microfluidics with a cross-junction producing spiral vortex and T-junction for double cell deformations. Very useful for high-throughput intracellular delivery. @acsnano https://t.co/feQJyQZfPI https://t.co/1gVQw3KSQ0

Jun 20, 2020 · 1 like · 1 share · 32 followers View post →
Gary Beane
@pollinus66 · X

RT @AsteronX: Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/4C4Y45L4Tz

Mar 23, 2020 · 1 share · 2,025 followers View post →
AsteronX
@AsteronX · X

Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/4C4Y45L4Tz

Mar 23, 2020 · 1 share · 831 followers View post →
Invictus Samael
@InvictusSamael · X

RT @BioconjChem: New #nanomaterial for #targeting and #drug #delivery: #spiral #hydroporator. Breaking #cell #membrane to deliver #cargo di…

Feb 29, 2020 · 3 shares · 660 followers View post →
Gary Beane
@pollinus66 · X

RT @BioconjChem: New #nanomaterial for #targeting and #drug #delivery: #spiral #hydroporator. Breaking #cell #membrane to deliver #cargo di…

Feb 28, 2020 · 3 shares · 2,025 followers View post →
Bioconjugate Chem
@BioconjChem · X

New #nanomaterial for #targeting and #drug #delivery: #spiral #hydroporator. Breaking #cell #membrane to deliver #cargo directly inside cells possible for #nanoparticles from 2 to 200nm! High efficiency, throughput, speed rate, and cell viability. @acsnano https://t.co/hqFfACtHo7 https://t.co/SJxhO5irnr

Feb 28, 2020 · 3 likes · 3 shares · 4,008 followers View post →
Drug Delivery News
@DeliveryDrug · X

RT @DeliveryDrug: Intracellular Nanomaterial Delivery Spiral Hydroporation.: In recent nanobiotechnology developments a wide variety of fun…

Feb 21, 2020 · 1 share · 1,338 followers View post →
Drug Delivery News
@DeliveryDrug · X

Intracellular Nanomaterial Delivery Spiral Hydroporation.: In recent nanobiotechnology developments a wide variety of functional nanomaterials and engineered biomolecules have been created and these have numerous applications in cell biology. For these… https://t.co/8b2J3sSQGf

Feb 19, 2020 · 1 share · 1,338 followers View post →
Dog News
@DogComment · X

RT @ac467: Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 19, 2020 · 4 shares · 261 followers View post →
Reem Khojah, PhD | بروف ريم خوجة
@reemkhojah · X

RT @ac467: Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 19, 2020 · 4 shares · 1,188 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @ac467: Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 18, 2020 · 4 shares · 2,588 followers View post →
Gary Beane
@pollinus66 · X

RT @ac467: Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 18, 2020 · 4 shares · 2,025 followers View post →
Aram Chung
@ac467 · X

Please check our new paper on @acsnano. Intracellular Nanomaterial Delivery via Spiral Hydroporation https://t.co/mPLrlAwmVS

Feb 18, 2020 · 12 likes · 4 shares · 243 followers View post →