The discussions exhibit a strong consensus on the potential of convalescent sera as a promising strategy, as seen in phrases like 'potential benefits' and 'more effective as prophylaxis,' while some posts caution about risks, highlighting the depth of engagement. The tone varies from optimistic to cautious, reflecting both scientific curiosity and prudence about current evidence.
AgreementModerate agreement
Most discussions acknowledge the potential benefits of convalescent sera for COVID-19 containment and treatment, especially as a prophylactic measure or early intervention.
InterestHigh interest
The discussions reflect high curiosity and concern about the therapy, with many posts referencing past experiences, current research, and scientific evaluations.
EngagementHigh engagement
Users actively analyze, question, and share detailed insights into the use, risks, and efficacy of convalescent sera, indicating deep engagement.
ImpactHigh impact
The emphasis on ongoing research, potential applications, and the historical and scientific context suggests these discussions could influence clinical approaches and policy considerations.
Abstract in brief
The text discusses the use of convalescent sera, which involves using blood plasma from recovered COVID-19 patients, as a strategy to treat or contain COVID-19.
It highlights the potential benefits of this approach, such as providing passive immunity to infected individuals and helping to control the spread of the virus.
The text might also mention challenges or considerations, like the need for proper testing and matching of donors and recipients, to ensure safety and effectiveness.
THREAD:
With the pharma giant Takeda announcing serious efforts to hasten the release of a CoVID-19 plasma-derived therapy (TAK-888), how optimistic should we be regarding a chance for a cure?
https://t.co/Y8n5MoqAdD
Mar 16, 2020 · 24 likes · 4 shares · 1,441 followersView post →
May 12, 2020 · 15 likes · 2 shares · 4,569 followersView post →
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Elaine Bignell
@ElaineBignell · X
The convalescent sera option for containing COVID-19. Balanced assessment of benefits and risks by Casadevall & Pirofski. https://t.co/ZKELI5Q7lg
Mar 26, 2020 · 8 likes · 3 shares · 1,686 followersView post →
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Peter Lansberg MDPhD
@lansberg · X
@VPrasadMDMPH One option that should be explored is harvesting AB from convalescent plasma (using apheresis) - this could be effective to immunize hospital staff. The most important resource that should be protected for uninterrupted care of Covid 19 patients https://t.co/rnh7Ij1EMs #COVID19 https://t.co/cGrK5fKUth
Mar 21, 2020 · 7 likes · 3 shares · 2,640 followersView post →
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SEInmunología
@SEinmunologia · X
(2/4) ¿Qué artículos se han usado para esta Parte 3?
- Tratamientos experimentales: https://t.co/AbJhnxDaWt
- Plasmaterapia: https://t.co/KY8FpRhsbJ
- Vacuna: https://t.co/26AyWJ0vrd
May 5, 2020 · 6 likes · 3 shares · 10,399 followersView post →
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gloria s. antolin
@gsanchezantolin · X
Si los Anticuerpos no son protectores por que se plantean ensayos de tratamiento con suero hiperinmune? @DrLejarazu . ¿Que sabemos de esto? JCI - The convalescent sera option for containing COVID-19 @MagdalenaSalced @nachorosell https://t.co/qdKhzFMai8
This video explains how the SARS-CoV-2 virus infects the body and how neutralizing antibodies in plasma from recovered patients may offer potential treatment options. It highlights the importance of vaccines and ongoing…
This episode discusses case management of suspected COVID-19 patients, including diagnostic approaches, treatment options, and vaccination. It also covers the use of convalescent sera from recovered patients as a…
@cesardeleon015 @mayogastro En la epidemia de SARS COV 1 del 2003 ese fue el manejo con los pacientes. https://t.co/xRROOOEb6Y incluyo las referencias de un estudio que repasa esos procedimientos
@AP4Liberty @justinamash Rx Right to Try would have been nice if implemented in February instead of Hydroxychloriquine Fhitposting from Teump.
Dismantling Pandemic Response Team left FDA right in the way of Convalescent Plasma, the $30 version of Trump's $450MM REGN-COV2
https://t.co/4wrcR90U4m
@ScottAdamsSays "Depending on the antibody amount and composition, the protection conferred by the transferred immunoglobulin can last from weeks to months."
https://t.co/iEwHyOIWY2
Are we going to drain people forever? Since no immunity is ever actually built in the body, no herd immunity.
Uso de plasma de sangre de personas recuperadas para tratamiento y prevención, ¿la vía más viable de contener COVID19 en el corto plazo? https://t.co/4radwK4dvr
Se están realizando esfuerzos para fabricar gamma globulina terapéutica a partir de sueros convalecientes COVID-19, o alternativamente para obtener anticuerpos monoclonales neutralizantes.
https://t.co/vKePHfOLHC
https://t.co/YkhVAKAHeJ
Jun 9, 2020 · 4 likes · 45,569 followersView post →
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The Plasma Professor
@petermjaworski · X
RT @jclinicalinvest: Scientists put survivors' blood plasma to the test (via @ScienceMagazine highlights the Liise-Anne Pirofski @EinsteinM…
May 30, 2020 · 4 shares · 2,338 followersView post →
JR
john randall
@johnran28545123 · X
RT @jclinicalinvest: Scientists put survivors' blood plasma to the test (via @ScienceMagazine highlights the Liise-Anne Pirofski @EinsteinM…
May 29, 2020 · 4 shares · 136 followersView post →
PZ
Pr Dr ZOUAGHI-
@DrZouaghi · X
RT @jclinicalinvest: Scientists put survivors' blood plasma to the test (via @ScienceMagazine highlights the Liise-Anne Pirofski @EinsteinM…
May 29, 2020 · 4 shares · 3,558 followersView post →
PC
Patrick CHAHUNEAU
@PatrickCHAHUNE1 · X
RT @jclinicalinvest: Scientists put survivors' blood plasma to the test (via @ScienceMagazine highlights the Liise-Anne Pirofski @EinsteinM…
May 29, 2020 · 4 shares · 687 followersView post →
JI
Journal of Clinical Investigation
@jclinicalinvest · X
Scientists put survivors' blood plasma to the test (via @ScienceMagazine highlights the Liise-Anne Pirofski @EinsteinMed and @ACasadevall1 @HopkinsMedicine article in JCI) https://t.co/lLVsYji4Fl
https://t.co/GsWRtsYN3K
May 29, 2020 · 4 likes · 4 shares · 51,094 followersView post →
PT
pedro trujillano
@ptrujillano · X
RT @EricTopol: A new @jclinicalinvest commentary suggesting the use of serum from people who have recovered from #COVID19 as a potential pr…
May 28, 2020 · 284 shares · 1,718 followersView post →
SW
Sabina Walker
@SabinaWalker18 · X
RT @EricTopol: A new @jclinicalinvest commentary suggesting the use of serum from people who have recovered from #COVID19 as a potential pr…
May 28, 2020 · 284 shares · 2,067 followersView post →
M
Malena
@MalenaCantu · X
RT @EricTopol: A new @jclinicalinvest commentary suggesting the use of serum from people who have recovered from #COVID19 as a potential pr…
May 27, 2020 · 284 shares · 193 followersView post →
ST
Stevan H. Thompson
@StevanHThompson · X
https://t.co/825VQeDvb1 Convalescent plasma for COVID-19 treatment. The use for high risk patients and patients who are not doing well.
May 12, 2020 · 15 likes · 2 shares · 4,569 followersView post →
I
ivand
@ivandellino · X
@luigimenze @Andrea_Clarck @Alessan00503442 @gib_barbara @Agenzia_Ansa Ha capito ciò che i suoi mezzi le consentono, come per la storia delle 3-4 settimane, totalmente fraintesa. Lo studio che preannuncia l'avvocato Venturi sarà letto quando i ricercatori lo pubblicheranno. Saluti l'amico immaginario, mentre altri studiano
https://t.co/Kz2ca0mLhB
The convalescent sera option for containing COVID-19
High Yield Points
* Convalescent plasma (CP) likely has some therapeutic benefit
* CP likely has more benefit as prophylaxis
* High risk groups may benefit from CP prophylax
Review by Sabrina Chen
https://t.co/BN1AdSebIW https://t.co/kux52btRJa
13 marzo 2020
Ricercatori della Johns Hopkins School of Public Health pubblicano uno studio sull'uso del Plasma in pazienti affetti da Covid-19
https://t.co/R8gMZ6wIhD
RT @SEinmunologia: (2/4) ¿Qué artículos se han usado para esta Parte 3?
- Tratamientos experimentales: https://t.co/AbJhnxDaWt
- Plasmater…
May 5, 2020 · 3 shares · 8,302 followersView post →
S
SEInmunología
@SEinmunologia · X
(2/4) ¿Qué artículos se han usado para esta Parte 3?
- Tratamientos experimentales: https://t.co/AbJhnxDaWt
- Plasmaterapia: https://t.co/KY8FpRhsbJ
- Vacuna: https://t.co/26AyWJ0vrd
May 5, 2020 · 6 likes · 3 shares · 10,399 followersView post →
@Glaivester @razibkhan @Steve_Sailer #1: probably simple suppression although still many unknowns. #2: plasma + massive exposure would have significant risk, as high level of inoculum could overwhelm passive antibody dose. Maybe passive Ab + low exposure could work? (good overview: https://t.co/xuFs5n6HQw)
@ArthurWeint @minsaude Arthur, vc que gosta de estudar, da uma olhada em plasma convalescente, é algo antigo. Que pode ser usado com profilaxia principalmente no profissionais de saúde. Vou deixar esse, mas no pubmed tem outros. https://t.co/Pi3PE4GTSD
@Clauwild1 Vou deixar um estudo aqui para vc ler. Da tudo sendo manipulado para não curar logo as pessoas https://t.co/Pi3PE4GTSD
Apr 23, 2020 · 1 like · 1,564 followersView post →
FF
Fabíola Faria
@FabiolaFaria · X
@wilsonwitzel @HEMORIO @SaudeGovRJ Seria interessante fazer o plasma nos profissionais que estão na.linha de frente, ele é profiláxico tb.
https://t.co/Pi3PE4GTSD
very interesting publications, Caution should be taken when applying the convalescent plasma therapy for COVID‐19:
https://t.co/jUaID7SOTy
https://t.co/P3saZba2LL
https://t.co/LebM42gusx
https://t.co/5ZqiD8iRhn
@OmaniMOH
@HalimaAlbulushi
@shabiba
“...experience suggests that convalescent sera may be more effective in preventing disease than in the treatment of established disease.” The convalescent sera option for containing COVID-19
Arturo Casadevall1 and Liise-anne Pirofski
Apr 15, 2020 · 1 like · 1 share · 2,785 followersView post →
RR
Rox Romo
@roxanamin · X
RT @jclinicalinvest: The convalescent sera option for containing COVID-19 https://t.co/GsWRtsYN3K
@ACasadevall1 and Liise-Anne Pirofski d…
Si los Anticuerpos no son protectores por que se plantean ensayos de tratamiento con suero hiperinmune? @DrLejarazu . ¿Que sabemos de esto? JCI - The convalescent sera option for containing COVID-19 @MagdalenaSalced @nachorosell https://t.co/qdKhzFMai8
RT @MFIG_Bignell: The convalescent sera option for containing COVID-19. Balanced assessment of benefits and risks by Casadevall & Pirofski…
Mar 26, 2020 · 3 shares · 621 followersView post →
RT
Reiko Tanaka
@TanakaGroup · X
RT @MFIG_Bignell: The convalescent sera option for containing COVID-19. Balanced assessment of benefits and risks by Casadevall & Pirofski…
Mar 26, 2020 · 3 shares · 636 followersView post →
HT
Hung-Ji Tsai
@HJTsai · X
RT @MFIG_Bignell: The convalescent sera option for containing COVID-19. Balanced assessment of benefits and risks by Casadevall & Pirofski…
Mar 26, 2020 · 3 shares · 1,009 followersView post →
EB
Elaine Bignell
@ElaineBignell · X
The convalescent sera option for containing COVID-19. Balanced assessment of benefits and risks by Casadevall & Pirofski. https://t.co/ZKELI5Q7lg
Mar 26, 2020 · 8 likes · 3 shares · 1,686 followersView post →
SC
Sahba Ferdowsi DO (conciergedoc)
@DrFerdowsi · X
RT @adib_elio: THREAD:
With the pharma giant Takeda announcing serious efforts to hasten the release of a CoVID-19 plasma-derived therapy (…
Mar 23, 2020 · 4 shares · 9,627 followersView post →
M
Martín
@FlashMC96 · X
45.- Las inmunoglobulinas procedentes de pacientes que han superado el COVID-19 pueden servir como profilaxis y como tto. Pero también pueden tener riesgos. Así se expone en el siguiente artículo publicado en JCI (The Journal of Clinical Investigation): https://t.co/9XaipiYzSE
Dear Microbiologist, Biotechnologist,
Please think and work on the development of drugs, vaccines for the challenging COVID-19. For Example
https://t.co/DEx6q9aAki
RT @lansberg: @VPrasadMDMPH One option that should be explored is harvesting AB from convalescent plasma (using apheresis) - this could be…
Mar 21, 2020 · 3 shares · 135 followersView post →
PM
Peter Lansberg MDPhD
@lansberg · X
@VPrasadMDMPH One option that should be explored is harvesting AB from convalescent plasma (using apheresis) - this could be effective to immunize hospital staff. The most important resource that should be protected for uninterrupted care of Covid 19 patients https://t.co/rnh7Ij1EMs #COVID19 https://t.co/cGrK5fKUth
Mar 21, 2020 · 7 likes · 3 shares · 2,640 followersView post →
MP
Marta Alonso Peña, PhD
@DraMartaAlonsoP · X
RT @DrJavierCrespo: Mirad este otro en el mismo sentido. J Clin Invest. 2020. https://t.co/vFqtRIEsp0.
@sepdigestiva @AEEHLiver @HUnivVald…
Mar 18, 2020 · 2 shares · 624 followersView post →
CH
Cynthia Hajal
@CynthiaHajal · X
RT @adib_elio: THREAD:
With the pharma giant Takeda announcing serious efforts to hasten the release of a CoVID-19 plasma-derived therapy (…
Mar 16, 2020 · 4 shares · 939 followersView post →
KB
Khalil Baddour
@KBadd · X
RT @adib_elio: THREAD:
With the pharma giant Takeda announcing serious efforts to hasten the release of a CoVID-19 plasma-derived therapy (…
Mar 16, 2020 · 4 shares · 759 followersView post →
EA
Elio Adib
@adib_elio · X
THREAD:
With the pharma giant Takeda announcing serious efforts to hasten the release of a CoVID-19 plasma-derived therapy (TAK-888), how optimistic should we be regarding a chance for a cure?
https://t.co/Y8n5MoqAdD
Mar 16, 2020 · 24 likes · 4 shares · 1,441 followersView post →
ML
Mayte Arias Loste
@MAriasLoste · X
RT @DrJavierCrespo: Mirad este otro en el mismo sentido. J Clin Invest. 2020. https://t.co/vFqtRIEsp0.
@sepdigestiva @AEEHLiver @HUnivVald…
Mar 14, 2020 · 2 shares · 314 followersView post →
JC
Javier Crespo
@DrJavierCrespo · X
Mirad este otro en el mismo sentido. J Clin Invest. 2020. https://t.co/vFqtRIEsp0.
@sepdigestiva @AEEHLiver @HUnivValdecilla @IDIVALdireccion @LabVaque https://t.co/TgPEf8h8Zg https://t.co/SEJVxSBxDX
Mar 14, 2020 · 3 likes · 2 shares · 5,899 followersView post →
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Cem şifa evi, Altınoluk. 481 beğenme · 1 kişi buradaydı. Bitkisel ürünler , yağlar , şifalı otlar , bitkisel tedavi kürleri bilgi sayfası..
The Convalescent Sera Option For Containing COVID-19: Arturo ...
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https://doi.org/10.1172/JCI138003. Viewpoint COVID-19. As of early 2020, humanity is confronting a pandemic in severe acute respiratory syndrome coronavirus ...
Convalescent plasma for COVID-19 in the intensive care unit
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doi: 10.1172/. JCI138003. 11. Li L, Zhang W, Hu Y, et al. Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and ...
Frontiers in Cellular and Infection Microbiology | PDF | Immune System
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The convalescent sera option for containing COVID-19. The Journal of Clinical Investigation, 130(4), 1545–1548. https://doi.org/10.1172/JCI138003. 2 ...
Structural insights into the cross-neutralization of SARS-CoV and ...
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doi:10.1172/JCI138003 Medline. 7. A. C. Cunningham, H. P. Goh, D. Koh, Treatment of COVID-19: Old tricks for new challenges. Crit. Care 24, 91 (2020). doi ...
Crippling life support for SARS-CoV-2 and other viruses through ...
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https://doi.org/10.1172/JCI138003. Casadevall, Arturo, Michael J Joyner, and Liise-Anne Pirofski. 2020. A Ran- domized Trial of Convalescent Plasma for COVID ...
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