ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies and facilitate implementation of delabeling strategies&safe β-lactam prescribing. New study @TrubianoJason @JAMAInternalMed #IDTwitter https://t.co/DHrwv0Bwtl https://t.co/bupqTfGSYQ
Development and Validation of a Penicillin Allergy Clinical Decision Rule.
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Mar 2020 – Jun 2025Where it's discussed
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X / Twitter148 posts
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Facebook8 posts
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AI synopsis
What people are saying
The discussions highlight various points of interest, such as references to the PEN-FAST score's intricacies and its practical utility in clinical settings. Phrases like 'high NPV' and 'simple tool for use' reflect a positive tone, emphasizing the rule's accessibility and significance. Posts mentioning that '98% patients had a NEGATIVE penicillin challenge’ underscore optimism regarding the tool's ability to improve patient outcomes, suggesting a strong belief in its practical application.
A large majority of discussions express support for the findings and recommendations presented in the article, indicating strong alignment with its conclusions.
The participants demonstrate a high level of curiosity and relevance towards the clinical decision rule, often expressing eagerness to read and implement its findings in practice.
While many posts show thoughtful consideration of the decision rule, the depth of engagement varies, with some posts simply describing the rule instead of delving into detailed analysis.
Most users believe that the publication has significant potential to influence clinical practice, particularly concerning the management of penicillin allergies.
Abstract in brief
- Penicillin allergy poses a major public health challenge, making it essential to develop validated clinical decision rules to identify low-risk allergies that don't need specialized skin testing.
- A study was conducted with 1,567 patients across Melbourne, Sydney, Perth, and Nashville, using logistic regression to create a penicillin allergy decision rule based on clinical factors predictive of allergy test results.
- The study identified four key features linked to positive penicillin allergy tests, providing a framework for point-of-care risk assessment in patients who report such allergies.
Top posts
Most liked on X and Blueskyペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin allergies at point-of-care https://t.co/QxDomeanhI
@StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a penicillin allergy - PEN-FAST: https://t.co/ISHejgeQDK A score of < 3 has NPV comparable to oral challenge Thank @TrubianoJason et al
Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
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Penicilline - eine Übersicht
Understanding Penicillin Allergy: Clinical Decision-Making Insights
Penicillin allergy poses a significant public health challenge. In this video, learn about a clinical decision rule developed from a study involving over 1,500 patients. Discover four key features that help identify…
RT @wjdeardorff: "Development and Validation of a Penicillin Allergy Clinical Decision Rule" (JAMA 2020) - https://t.co/s84hUriLCm PEN-FAST…
@j_n_foster Suggest reading https://t.co/nUWPFlJNYx and using https://t.co/JHLiIWESAE
Referências: 1) Pongdee T, Li JT. Evaluation and Management of Penicillin Allergy. Mayo Clin Proc. 2018 2) Blumenthal et al. Antibiotic allergy. Lancet. 2019 3) Trubiano et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med. 2020
AMPC経口チャレンジする患者はPEN-FASTで決定するといいかもよ https://t.co/cUWd24yoS5
@kaitlyn_mcsurdy ISCHEMIA https://t.co/tXaQ0GcA4d PEN-FAST https://t.co/Ea57hKTk2n EMPA-KIDNEY https://t.co/iwwARGuQif
2/ Le score PEN-FAST : Pen : penicillin allergy ? F : five years or less - 2 points A : angiodème/anaphylaxie - 2points ou S : réaction sévère anaphylactique - 2points T : traitement nécessaire (ou ne sait pas) pour la réaction. https://t.co/gxYrFgpE4s https://t.co/ul96ltQJxz
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
RT @TrubianoJason: We published #PENFAST in @JAMAInternalMed - 3-point CDR for #penicillinallergy - ⏰<5yrs (1-pt); #SCAR or Anaphylaxis/an…
We published #PENFAST in @JAMAInternalMed - 3-point CDR for #penicillinallergy - ⏰<5yrs (1-pt); #SCAR or Anaphylaxis/angioedema (2-pts); Rx (1-pt). A score of < 3 with a NPV 96.3%. Validated in
RT @FlorinDanPopesc:
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
RT @FlorinDanPopesc:
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RT @dave_hettle: Allergies need challenged to optimise #AMS + patient care - following on from @TrubianoJason's talk this morning. 98% pat…
Allergies need challenged to optimise #AMS + patient care - following on from @TrubianoJason's talk this morning. 98% patients had a NEGATIVE pencillin challenge despite 'Pen Allergy' label. Using tools like PEN-FAST (https://t.co/rExiydqJed) crucial to support this #ECCMID2023
@Bruce_M_Jones @esribes @Sefap_FAP #FAP_ICSCC https://t.co/ulWKzR0zQz
RT @Duke_ASET: PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
@rbganatra #3 you can almost always (99% of the time) use a beta-lactam. The data is good. https://t.co/EJYfqgLalM
▶️A provocação oral direta parece segura na maioria dos pacientes ▶️O uso da ferramenta PEN-FAST no manejo destes pacientes (veja em: https://t.co/1qy5rlgVM4) ▶️Desrotular os pacientes resultará em melhores resultados clínicos em um custo reduzido #IM2022 #ACP2022
Hmm, interesting. Pip/tazo for even more people? I'm sold! @katiewiskar @CollaborativeEM @adamdavidthomas https://t.co/tniWlus96f
RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
@StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a penicillin allergy - PEN-FAST: https://t.co/ISHejgeQDK A score of < 3 has NPV comparable to oral challenge Thank @TrubianoJason et al
@emcrit @PulmCrit lol penicillin allergy. (I KNOW, it exists, but it's super rare. Has anyone crunched the numbers / validated this PEN-FAST rule?) https://t.co/qjzxVGPeWQ https://t.co/P4i8SZb0cK
RT @medpedshosp: Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Interna…
Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Internal Medicine | JAMA Network https://t.co/m0nBepkPdq
#ECCMID2021 Good protocols exist risk stratifying Pen Allergy @JAMAInternalMed https://t.co/uzYwkgq7z7 Low Risk: Oral Challenge Intermediate: Skin-Test High Refer 4/N https://t.co/UMkE4em9M8
@Rachel_EMPharmD @PCC_PharmD @CriticalCareNow We've got a bell in the pharmacy to ring for vanco de-escalation, going to get one for this in the ED! Thanks PEN-FAST! https://t.co/bPqvcFsbxY
@ShreyaTrivediMD @zahirkanjee @BIDMC_Medicine @BIDMC_IM @bidhospitalists 7/ PEN-FAST: Clinical decision rule to de-list PCN allergies https://t.co/8Ye6Fq474K Bottom line: The PEN-FAST score identifies patients with a low risk of severe allergy who can safely undergo oral challenge.
Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/EPLYMOBPyE
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @Duke_ASET: PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-…
PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-FAST and a score <3 had a NPV of 96.3%. Allergy re-labeling can improve pt outcomes. doi:10.1001/jamainternmed.2020.0403 #USAAW20 #BeAntibioticsAware
RT @spjuraschek: Cool tool published in @JAMAInternalMed #AHA20 Development and Validation of a Penicillin Allergy Clinical Decision Rul…
Cool tool published in @JAMAInternalMed #AHA20 Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/jktxt6qBRw via @JAMAInternalMed part of @JAMANetwork https://t.co/PsDAR9RkfO
Simple test to assist in deciding appropriate periop #antibiotics Development and Validation of a Penicillin Allergy Clinical Decision Rule - PubMed https://t.co/2WyR3KG2fm
https://t.co/c83PDFgdxH
Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/h5XFU6yWT5
Our Stewardship program already does a great job with resident education. I have been considering implementing a clinical decision-making tool like PEN-FAST (Trubiano JA, Vogrin S, Chua KYL, et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule).
Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Internal Medicine | JAMA Network https://t.co/W6h9cX7dv5
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin allergies at point-of-care https://t.co/csnw6BPghq
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
https://t.co/WrOaHG2G0C #meded #medtwitter
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhhXhtp
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/NRs3pnDEcF https://t.co/pNFcJP4W9e
New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhhXhtp
Development and Validation of a #Penicillin #Allergy Clinical Decision Rule: https://t.co/KcxSm6iPFd
Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/h8kPurHq4d
https://t.co/OWGwZYt3mY
New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhieSkX
Development and Validation of a Penicillin Allergy Clinical Decision Rule. https://t.co/gtWAyECq8l #ReadByQxMD
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @JAMAInternalMed: https://t.co/IN3Acjw9Nq
https://t.co/IN3Acjw9Nq
Just to cleanse your twitter feed of COVID - check out the use of the PEN-FAST criteria to rule out true penicillin allergy. Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/WRUxa44IJX @JAMAInternalMed #AHNIMres
Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/SgTEdBMZIE
Algo no #COVIDー19 , pero importante igual: #PENFAST para definir alergia a penicilina: - Cuestionario con 96% VPN - 945 pacientes de validación externa - Buena herramienta de stewardship para definir a quien testear/tratar con seguridad
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies and facilitate implementation of delabeling strategies&safe β-lactam prescribing. New study @TrubianoJason @JAMAInternalMed #IDTwitter https://t.co/DHrwv0Bwtl https://t.co/bupqTfGSYQ
https://t.co/Hrggqorra1 RT @OCPhA_CA: Development and validation of a penicillin allergy clinical decision rule https://t.co/CKvXmrMq61 #pharmacists #pharmacy #health #healthcare
Development and validation of a penicillin allergy clinical decision rule https://t.co/PCWz4osUSK #pharmacists #pharmacy #health #healthcare
"Development and Validation of a Penicillin Allergy Clinical Decision Rule" (JAMA 2020) - https://t.co/s84hUriLCm PEN-FAST: penicillin allergy, five or fewer years ago, anaphylaxis/angioedema, severe cutaneous adverse reaction, and tx required for allergy episode https://t.co/UxLkcIxPyI
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/Hpxinq6QOd
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/PBvQn2c47i https://t.co/ICCHOtZ23s
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin allergies at point-of-care https://t.co/QxDomeanhI