Development and Validation of a Penicillin Allergy Clinical Decision Rule.

Jason A Trubiano, Sara Vogrin, Kyra Y L Chua, Jack Bourke, James Yun, Abby Douglas, Cosby A Stone, Roger Yu, Lauren Groenendijk, Natasha E Holmes, Elizabeth J Phillips

May 2020 JAMA Intern Med

Synopsis of Social media discussions

The discussions highlight various points of interest, such as references to the PEN-FAST score's intricacies and its practical utility in clinical settings. Phrases like 'high NPV' and 'simple tool for use' reflect a positive tone, emphasizing the rule's accessibility and significance. Posts mentioning that '98% patients had a NEGATIVE penicillin challenge’ underscore optimism regarding the tool's ability to improve patient outcomes, suggesting a strong belief in its practical application.

A
Agreement
 Strong agreement

A large majority of discussions express support for the findings and recommendations presented in the article, indicating strong alignment with its conclusions.

I
Interest
 High level of interest

The participants demonstrate a high level of curiosity and relevance towards the clinical decision rule, often expressing eagerness to read and implement its findings in practice.

E
Engagement
 Moderate level of engagement

While many posts show thoughtful consideration of the decision rule, the depth of engagement varies, with some posts simply describing the rule instead of delving into detailed analysis.

I
Impact
 High level of impact

Most users believe that the publication has significant potential to influence clinical practice, particularly concerning the management of penicillin allergies.

Social Mentions

YouTube

2 Videos

Facebook

8 Posts

Twitter

148 Posts

Blogs

4 Articles

News

36 Articles

Metrics

Video Views

446

Total Likes

423

Extended Reach

971,336

Social Features

198

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Karolyi & Kuran - Pharmakologie & Innere Medizin

September 30, 2024

393 views

Understanding Penicillin Allergy: Clinical Decision-Making Insights

Understanding Penicillin Allergy: Clinical Decision-Making Insights

Penicillin allergy poses a significant public health challenge. In this video, learn about a clinical decision rule developed from a study involving over 1,500 patients. Discover four key features that help identify low-risk allergies avoid unnecessary skin testing.

Ana Elisa | Médica Infectologista

August 29, 2024

53 views

  • Josué Monreal
    @DJosmonreal (Twitter)


    view full post

    June 30, 2025

    2

  • จ๋อง
    @panupong_mtnd (Twitter)

    RT @wjdeardorff: "Development and Validation of a Penicillin Allergy Clinical Decision Rule" (JAMA 2020) - https://t.co/s84hUriLCm PEN-FAST…
    view full post

    April 26, 2025

    1

  • Claire Kamaliddin
    @Clairekamalid (Twitter)

    @j_n_foster Suggest reading https://t.co/nUWPFlJNYx and using https://t.co/JHLiIWESAE
    view full post

    September 16, 2024

    1

  • ensaio imunoenzimático
    @souelisaso (Twitter)

    Referências: 1) Pongdee T, Li JT. Evaluation and Management of Penicillin Allergy. Mayo Clin Proc. 2018 2) Blumenthal et al. Antibiotic allergy. Lancet. 2019 3) Trubiano et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med. 2020
    view full post

    August 29, 2024

    3

  • ふとねこ
    @BigFatCat7 (Twitter)

    AMPC経口チャレンジする患者はPEN-FASTで決定するといいかもよ https://t.co/cUWd24yoS5
    view full post

    February 11, 2024

    5

  • Willy Frick
    @willyhfrick (Twitter)

    @kaitlyn_mcsurdy ISCHEMIA https://t.co/tXaQ0GcA4d PEN-FAST https://t.co/Ea57hKTk2n EMPA-KIDNEY https://t.co/iwwARGuQif
    view full post

    January 13, 2024

    6

  • MARY Aurélien
    @MARYau_MCU_PH (Twitter)

    2/ Le score PEN-FAST : Pen : penicillin allergy ? F : five years or less - 2 points A : angiodème/anaphylaxie - 2points ou S : réaction sévère anaphylactique - 2points T : traitement nécessaire (ou ne sait pas) pour la réaction. https://t.co/gxYrFgpE4s https://t.co/ul96ltQJxz
    view full post

    August 31, 2023

    1

  • DrDoobeliou
    @Babyd0k (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 26, 2023

    9

  • matpirat
    @matpirat (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 26, 2023

    9

  • Marchand de Sable
    @marchand_de (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 26, 2023

    9

  • nfkb
    @nfkb (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 26, 2023

    9

  • Edú Quiroz
    @Edu_qm (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 26, 2023

    9

  • Matthieu Jabaudon
    @mj0b (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 25, 2023

    9

  • Adnane Lahlou
    @mac_eden (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 25, 2023

    9

  • Maxime Renaux
    @Fauconnoir0 (Twitter)

    RT @ArthurJamesMD: Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 25, 2023

    9

  • Arthur James
    @ArthurJamesMD (Twitter)

    Une preuve de plus que chez les patients à faible risque allergique l’administration de pénicilline est safe
    view full post

    July 25, 2023

    25

    9

  • Nancy Szakacsy m.s. lmft
    @NancySzakacsy (Twitter)

    RT @TrubianoJason: We published #PENFAST in @JAMAInternalMed - 3-point CDR for #penicillinallergy - ⏰<5yrs (1-pt); #SCAR or Anaphylaxis/an…
    view full post

    July 19, 2023

    1

  • Jason Trubiano
    @TrubianoJason (Twitter)

    We published #PENFAST in @JAMAInternalMed - 3-point CDR for #penicillinallergy - ⏰<5yrs (1-pt); #SCAR or Anaphylaxis/angioedema (2-pts); Rx (1-pt). A score of < 3 with a NPV 96.3%. Validated in
    view full post

    July 18, 2023

    7

    1

  • FaRa Ra MD
    @farara82 (Twitter)

    RT @FlorinDanPopesc:
    view full post

    July 17, 2023

    12

  • ぽん@
    @pharma_pon (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    July 4, 2023

    9

  • Q
    @Q_serph (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    July 4, 2023

    9

  • 感染少尉
    @racketandmd (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 26, 2023

    9

  • 加藤フウパンダ
    @JdzYEjuIGCTFXXY (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    9

  • かるだん
    @nishikoriracket (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    9

  • 晒しな日記
    @tkyk3104 (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    9

  • おくすりクソ野郎
    @2Yackyack (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    9

  • hataboSAN
    @hataboSAN (Twitter)

    RT @pinacol: ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    9

  • pinacol
    @pinacol (Twitter)

    ペニシリンアレルギー低リスクを判別するためのルール、PEN-FAST。 https://t.co/TgvveJjCkL
    view full post

    June 25, 2023

    82

    9

  • Mohamed Hisham, PharmD., BCCCP., BCIDP
    @HishamZenith (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 30, 2023

    12

  • PALACE Trial
    @PALACE_Trial (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 30, 2023

    12

  • Ana Copaescu
    @AnaCopaescu (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • Pinitrius Petrekas
    @pinitrius (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • Joe De Luca
    @DrJoeDeluca (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • Dragos Casu
    @dragos_casu (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • Kimberly Blumenthal, MD, MSc
    @KimberlyBlumen1 (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • GR
    @Gabriele_Rumi (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 29, 2023

    12

  • Kamol
    @KamolMU (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 28, 2023

    12

  • Jason Trubiano
    @TrubianoJason (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 28, 2023

    12

  • Florin-Dan
    @florindanpopesq (Twitter)

    RT @FlorinDanPopesc:
    view full post

    April 28, 2023

    12

  • Florin-Dan Popescu
    @FlorinDanPopesc (Twitter)


    view full post

    April 28, 2023

    39

    12

  • Kerry Holden
    @KezHolden (Twitter)

    RT @dave_hettle: Allergies need challenged to optimise #AMS + patient care - following on from @TrubianoJason's talk this morning. 98% pat…
    view full post

    April 15, 2023

    1

  • David Hettle (Bluesky in bio)
    @dave_hettle (Twitter)

    Allergies need challenged to optimise #AMS + patient care - following on from @TrubianoJason's talk this morning. 98% patients had a NEGATIVE pencillin challenge despite 'Pen Allergy' label. Using tools like PEN-FAST (https://t.co/rExiydqJed) crucial to support this #ECCMID2023
    view full post

    April 15, 2023

    3

    1

  • Anna Bonet Esteve
    @annabonet (Twitter)

    @Bruce_M_Jones @esribes @Sefap_FAP #FAP_ICSCC https://t.co/ulWKzR0zQz
    view full post

    December 11, 2022

  • PALACE Trial
    @PALACE_Trial (Twitter)

    RT @Duke_ASET: PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-…
    view full post

    October 21, 2022

    2

  • PALACE Trial
    @PALACE_Trial (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    October 21, 2022

    36

  • Katie Schlosser
    @KT_Schlosser (Twitter)

    @rbganatra #3 you can almost always (99% of the time) use a beta-lactam. The data is good. https://t.co/EJYfqgLalM
    view full post

    September 25, 2022

    2

  • PEBMED
    @pebmed (Twitter)

    ▶️A provocação oral direta parece segura na maioria dos pacientes ▶️O uso da ferramenta PEN-FAST no manejo destes pacientes (veja em: https://t.co/1qy5rlgVM4) ▶️Desrotular os pacientes resultará em melhores resultados clínicos em um custo reduzido #IM2022 #ACP2022
    view full post

    April 30, 2022

  • Allan Lai
    @RespRate16 (Twitter)

    Hmm, interesting. Pip/tazo for even more people? I'm sold! @katiewiskar @CollaborativeEM @adamdavidthomas https://t.co/tniWlus96f
    view full post

    November 15, 2021

    3

  • G.M. Pozzetti
    @gmpozzetti (Twitter)

    RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
    view full post

    September 24, 2021

    6

  • Nolene
    @geapeatrainee (Twitter)

    RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
    view full post

    September 24, 2021

    6

  • Matt Taylor
    @matttnz (Twitter)

    RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
    view full post

    September 24, 2021

    6

  • kenyatta comrade
    @Comrade_Ke (Twitter)

    RT @rbganatra: @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a pen…
    view full post

    September 24, 2021

    6

  • Rahul Ganatra
    @rbganatra (Twitter)

    @StSenka @thatgirl409 There is now a really simple tool for use at the point-of-care to risk stratify people reporting a penicillin allergy - PEN-FAST: https://t.co/ISHejgeQDK A score of < 3 has NPV comparable to oral challenge Thank @TrubianoJason et al
    view full post

    September 23, 2021

    29

    6

  • Michael Sharma, PA-C ⚕️
    @michaelsharmapa (Twitter)

    @emcrit @PulmCrit lol penicillin allergy. (I KNOW, it exists, but it's super rare. Has anyone crunched the numbers / validated this PEN-FAST rule?) https://t.co/qjzxVGPeWQ https://t.co/P4i8SZb0cK
    view full post

    July 28, 2021

    1

  • Ian medical
    @IanMedical (Twitter)

    RT @medpedshosp: Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Interna…
    view full post

    July 17, 2021

    1

  • Med Peds Hospitalist
    @medpedshosp (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Internal Medicine | JAMA Network https://t.co/m0nBepkPdq
    view full post

    July 17, 2021

    1

    1

  • Michael Marks
    @dr_michaelmarks (Twitter)

    #ECCMID2021 Good protocols exist risk stratifying Pen Allergy @JAMAInternalMed https://t.co/uzYwkgq7z7 Low Risk: Oral Challenge Intermediate: Skin-Test High Refer 4/N https://t.co/UMkE4em9M8
    view full post

    July 11, 2021

    5

  • Daniel Giddings
    @PharmerDaniel (Twitter)

    @Rachel_EMPharmD @PCC_PharmD @CriticalCareNow We've got a bell in the pharmacy to ring for vanco de-escalation, going to get one for this in the ED! Thanks PEN-FAST! https://t.co/bPqvcFsbxY
    view full post

    April 17, 2021

    3

  • Rahul Ganatra
    @rbganatra (Twitter)

    @ShreyaTrivediMD @zahirkanjee @BIDMC_Medicine @BIDMC_IM @bidhospitalists 7/ PEN-FAST: Clinical decision rule to de-list PCN allergies https://t.co/8Ye6Fq474K Bottom line: The PEN-FAST score identifies patients with a low risk of severe allergy who can safely undergo oral challenge.
    view full post

    March 19, 2021

    2

  • noel cole
    @aussiecoley (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/EPLYMOBPyE
    view full post

    December 30, 2020

  • Antibiotic Steward Bassam Ghanem
    @ABsteward (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    December 24, 2020

    36

  • Ben T
    @ABXsteward (Twitter)

    RT @Duke_ASET: PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-…
    view full post

    November 23, 2020

    2

  • Duke Antimicrobial Stewardship
    @Duke_ASET (Twitter)

    PCN allergies assoc with AMR and poor patient outcomes. 4 features assoc with a positive PCN allergy test summarized in PEN-FAST and a score <3 had a NPV of 96.3%. Allergy re-labeling can improve pt outcomes. doi:10.1001/jamainternmed.2020.0403 #USAAW20 #BeAntibioticsAware
    view full post

    November 23, 2020

    5

    2

  • Mariana Sbaraini, MD, PhD
    @marisbaraini (Twitter)

    RT @spjuraschek: Cool tool published in @JAMAInternalMed #AHA20 Development and Validation of a Penicillin Allergy Clinical Decision Rul…
    view full post

    November 18, 2020

    1

  • Stephen Juraschek MD, PhD, FAHA, AHSCP-CHS
    @spjuraschek (Twitter)

    Cool tool published in @JAMAInternalMed #AHA20 Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/jktxt6qBRw via @JAMAInternalMed part of @JAMANetwork https://t.co/PsDAR9RkfO
    view full post

    November 16, 2020

    3

    1

  • Robert Gaiser, MD
    @RobertGaiser1 (Twitter)

    Simple test to assist in deciding appropriate periop #antibiotics Development and Validation of a Penicillin Allergy Clinical Decision Rule - PubMed https://t.co/2WyR3KG2fm
    view full post

    August 19, 2020

    2

  • Juan Emiro Herrera
    @JuanEmiro (Twitter)

    https://t.co/c83PDFgdxH
    view full post

    August 4, 2020

  • Robert Zhang MD
    @robertshiuzhang (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/h5XFU6yWT5
    view full post

    July 28, 2020

  • Kaleb Wolfe
    @Kalebsiella (Twitter)

    Our Stewardship program already does a great job with resident education. I have been considering implementing a clinical decision-making tool like PEN-FAST (Trubiano JA, Vogrin S, Chua KYL, et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule).
    view full post

    July 28, 2020

  • Lucidity_rehab
    @Lucidity_rehab (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule | Allergy and Clinical Immunology | JAMA Internal Medicine | JAMA Network https://t.co/W6h9cX7dv5
    view full post

    June 8, 2020

  • T.kimura
    @jjcrazydiamond (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    May 29, 2020

    2

  • Todd C. Lee
    @DrToddLee (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    May 29, 2020

    2

  • JAMA Internal Medicine
    @JAMAInternalMed (Twitter)

    PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin allergies at point-of-care https://t.co/csnw6BPghq
    view full post

    May 29, 2020

    12

    2

  • HUGO COLOMBO MD
    @HCOLOMBO1958 (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 26, 2020

    6

  • Dr. Angelo Martinez Urb.
    @DrAmartinezur93 (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 26, 2020

    6

  • JAMA Internal Medicine
    @JAMAInternalMed (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 26, 2020

    6

  • NOZAWA, Satoshi
    @st_nozawa (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 19, 2020

    6

  • Ian medical
    @IanMedical (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 19, 2020

    6

  • JAMA Network
    @JAMANetwork (Twitter)

    RT @JAMAInternalMed: https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 19, 2020

    6

  • JAMA Internal Medicine
    @JAMAInternalMed (Twitter)

    https://t.co/WrOaHG2G0C #meded #medtwitter
    view full post

    May 19, 2020

    13

    6

  • CNET
    @cnet_therap (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 13, 2020

    8

  • Trip Database
    @tripdatabase (Twitter)

    New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhhXhtp
    view full post

    May 12, 2020

  • CRPV_Lille
    @CRPV_Lille (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 12, 2020

    8

  • Laurent Chouchana
    @LChouchana (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 12, 2020

    8

  • Luu-Ly Do-Quang
    @LuuLyAPM (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 12, 2020

    8

  • CRPV_Limoges
    @CRPV_Limoges (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 12, 2020

    8

  • grØdy #(JeSuisVaccinée)^2
    @grdy2 (Twitter)

    RT @Reseau_CRPV: Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validatio…
    view full post

    May 12, 2020

    8

  • Compte officiel du Réseau FR des CRPV
    @Reseau_CRPV (Twitter)

    Un outil simple d'aide à la décision chez les patients rapportant une allergie à la pénicilline Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/NRs3pnDEcF https://t.co/pNFcJP4W9e
    view full post

    May 12, 2020

    12

    8

  • Trip Database
    @tripdatabase (Twitter)

    New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhhXhtp
    view full post

    May 5, 2020

  • Ray DuBois, MD, PhD
    @Rndubois (Twitter)

    Development and Validation of a #Penicillin #Allergy Clinical Decision Rule: https://t.co/KcxSm6iPFd
    view full post

    May 5, 2020

  • B.Tomlow
    @btomlow (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/h8kPurHq4d
    view full post

    May 5, 2020

  • Martin Krsak
    @MightKnot (Twitter)

    https://t.co/OWGwZYt3mY
    view full post

    April 26, 2020

  • Trip Database
    @tripdatabase (Twitter)

    New2Trip: Development & Validation of Penicillin Allergy Clinical Decision Rule https://t.co/1N6vhieSkX
    view full post

    April 25, 2020

  • Jose Manuel Caro
    @jmanuelcaro (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule. https://t.co/gtWAyECq8l #ReadByQxMD
    view full post

    April 22, 2020

  • GR
    @Gabriele_Rumi (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    April 18, 2020

    36

  • Debbie Rigby
    @DRugby56 (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    April 18, 2020

    36

  • dan reyes
    @dalregu (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    April 18, 2020

    36

  • Jason Trubiano
    @TrubianoJason (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    April 18, 2020

    36

  • Ian medical
    @IanMedical (Twitter)

    RT @JAMAInternalMed: https://t.co/IN3Acjw9Nq
    view full post

    April 12, 2020

    1

  • JAMA Internal Medicine
    @JAMAInternalMed (Twitter)

    https://t.co/IN3Acjw9Nq
    view full post

    April 12, 2020

    5

    1

  • Collin Flanagan
    @collinflan (Twitter)

    Just to cleanse your twitter feed of COVID - check out the use of the PEN-FAST criteria to rule out true penicillin allergy. Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/WRUxa44IJX @JAMAInternalMed #AHNIMres
    view full post

    April 7, 2020

  • A.R. García
    @air_garcia (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/SgTEdBMZIE
    view full post

    April 1, 2020

  • Alejandro Kral Bravo
    @alejandrokralb (Twitter)

    Algo no #COVIDー19 , pero importante igual: #PENFAST para definir alergia a penicilina: - Cuestionario con 96% VPN - 945 pacientes de validación externa - Buena herramienta de stewardship para definir a quien testear/tratar con seguridad
    view full post

    March 31, 2020

    3

  • Justine Choe
    @JustineChoe (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • T.kimura
    @jjcrazydiamond (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Abhi
    @kumar_drabhi (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Nazlee
    @nazlee_g (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Chris Little PhD
    @drcjlittle (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Antibiotic Steward Bassam Ghanem
    @ABsteward (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Centre for Antibiotic Allergy & Research
    @CAAR_Aus (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Ohide Otome
    @olohiu (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 23, 2020

    36

  • Julia Sapozhnikov
    @JuliaPharm (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Rocio Fdez Urrusuno
    @Rocioluarca (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Carolina Gutiérrez
    @_caritoo (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Ignacio Alvarez
    @IgnacioAlvRod (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Amber B Clemmons
    @ABC_PharmD (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Chris Bland
    @blandman19 (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Jorge Abarca ®
    @jabarcag (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • LeonorPeriañez
    @leonorperianez (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Jamie Legaspi
    @JL_IDpharm (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Ukwen Akpoji
    @abx_dontgoviral (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Don Branam
    @Branamycin (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Wes Kufel
    @WesKufel (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Trinh Vu
    @pharmertrinh (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Brandon Opitz, PharmD, BCPS, BCIDP
    @brandon_opitz (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Kamol
    @KamolMU (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Julie Ann Justo
    @julie_justo (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Eric Macy
    @EricMacyMD (Twitter)

    RT @ABsteward: ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies an…
    view full post

    March 22, 2020

    36

  • Antibiotic Steward Bassam Ghanem
    @ABsteward (Twitter)

    ICYMI PEN-FAST is a practical tool with a high "96.3%" NPV uses penicillin allergy history to identify low-risk allergies and facilitate implementation of delabeling strategies&safe β-lactam prescribing. New study @TrubianoJason @JAMAInternalMed #IDTwitter https://t.co/DHrwv0Bwtl https://t.co/bupqTfGSYQ
    view full post

    March 22, 2020

    94

    36

  • SB Mahapatra
    @sbmahapatra1 (Twitter)

    https://t.co/Hrggqorra1 RT @OCPhA_CA: Development and validation of a penicillin allergy clinical decision rule https://t.co/CKvXmrMq61 #pharmacists #pharmacy #health #healthcare
    view full post

    March 20, 2020

  • OCPhA
    @OCPhA_CA (Twitter)

    Development and validation of a penicillin allergy clinical decision rule https://t.co/PCWz4osUSK #pharmacists #pharmacy #health #healthcare
    view full post

    March 20, 2020

  • James Deardorff
    @wjdeardorff (Twitter)

    "Development and Validation of a Penicillin Allergy Clinical Decision Rule" (JAMA 2020) - https://t.co/s84hUriLCm PEN-FAST: penicillin allergy, five or fewer years ago, anaphylaxis/angioedema, severe cutaneous adverse reaction, and tx required for allergy episode https://t.co/UxLkcIxPyI
    view full post

    March 17, 2020

    2

    1

  • SLaai
    @SocLatAlergia (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 17, 2020

    7

  • ARIAguideline
    @ARIAGuideline (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 17, 2020

    7

  • Fundación Libra
    @FUNDACIONLIBRA (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 17, 2020

    7

  • Interasma
    @Interasma (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 17, 2020

    7

  • T.kimura
    @jjcrazydiamond (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • Juan C Ivancevich MD
    @Aller_MD (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 16, 2020

    7

  • AL-BLOWI, WAEL F. M.
    @ABU_TALEEN82 (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 16, 2020

    7

  • Brian Schroer MD
    @Brian34Schroer (Twitter)

    RT @wheezemd: Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a…
    view full post

    March 16, 2020

    7

  • Michael Blaiss, MD
    @wheezemd (Twitter)

    Very interesting study on a risk tool to determine if penicillin allergy testing is needed. --Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/Hpxinq6QOd
    view full post

    March 16, 2020

    4

    7

  • Angel Marcos Fendian
    @Amfendian (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • Yoshiki Kusama
    @stone_bagle (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • Kendra (Swick) Stilwell
    @ktswick (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • Moises Salgado, MD
    @Moises_SdM (Twitter)

    Development and Validation of a Penicillin Allergy Clinical Decision Rule https://t.co/PBvQn2c47i https://t.co/ICCHOtZ23s
    view full post

    March 16, 2020

    1

  • El Chepo Gwapo.BTC
    @DrGwapoLeon (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • Tom Quinn etc.
    @proftomquinn (Twitter)

    RT @JAMAInternalMed: PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin aller…
    view full post

    March 16, 2020

    17

  • JAMA Internal Medicine
    @JAMAInternalMed (Twitter)

    PEN-FAST is a #penicillinallergy assessment clinical decision rule that risk-stratifies patients with penicillin allergies at point-of-care https://t.co/QxDomeanhI
    view full post

    March 16, 2020

    30

    17

Abstract Synopsis

  • Penicillin allergy poses a major public health challenge, making it essential to develop validated clinical decision rules to identify low-risk allergies that don't need specialized skin testing.
  • A study was conducted with 1,567 patients across Melbourne, Sydney, Perth, and Nashville, using logistic regression to create a penicillin allergy decision rule based on clinical factors predictive of allergy test results.
  • The study identified four key features linked to positive penicillin allergy tests, providing a framework for point-of-care risk assessment in patients who report such allergies.