Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid19. Ahora sabemos que no hace nada pero en marzo se lo pusimos a todos. ¡Y se tolera fatal! Ya no lo estamos usando. https://t.co/DK1LJfDtj1
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.
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Mar 2020 – Nov 2025Where it's discussed
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Bluesky102 posts
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AI synopsis
What people are saying
The discussions heavily focus on the trial results, with quotes like 'no benefit observed' and 'significant rate of adverse events,' emphasizing disappointment and disapproval. The tone is mostly dismissive and repetitive, reflecting a consensus that the studied medication is ineffective, which contributes to the overall negative impact score.
Most posts clearly emphasize that the clinical trials showed no benefit for lopinavir-ritonavir in treating severe COVID-19, demonstrating strong disagreement with its efficacy.
Posts display low interest in the studied drug’s potential, focusing instead on the negative trial outcomes and disapproval, suggesting limited engagement with alternative perspectives.
Posts exhibit dismissiveness and lack of deep analysis, mainly recycling trial results and commenting on their ineffectiveness without much discussion or exploration of broader implications.
The overall sentiment indicates that the publication has negligible influence on changing opinions or practices, as most users reinforce the trial’s negative findings without proposing new ideas or solutions.
Abstract in brief
- No effective treatments have been established for severe SARS-CoV-2 illness, leading to a trial of lopinavir-ritonavir versus standard care in hospitalized patients.
- The study included 199 patients with confirmed infections, randomly assigned to either the treatment group or standard care.
- Results showed no significant difference in clinical improvement or mortality rates between the two groups, though lopinavir-ritonavir showed a marginally faster time to improvement and more gastrointestinal side effects.
Top posts
Most liked on X and BlueskyIn this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19,” published by NEJM on March 18. #COVID19 #SARSCoV2
Lopinavir–Ritonavir en #COVID19 severo:
3/ Bu ısmarlama makalede lopinavir verilme günü medyan onüç, yani viral aktivite bittikten sonra. Yani makale tamamen çöp. Paxlovidi ise ilk üç dünde başlamak öneriliyor. Biz lopinaviri ilk beş günde kullandık. 10.1056/nejmoa2001282 https://t.co/oQ2CVUbgEG
@HalukVAHABOLU Haklisiniz! FDA EUA vermis! E zaten benzer mekanizmayla calisan ilac Covid suresince onayli olarak kullaniliyordu! Bu hafta bol bol zoom reklamlari var! Yakinda Bizde de recetelerde yerini alacaktir! https://t.co/2xnwxxETer
@HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
All mentions
Evaluating Treatments for Severe COVID-19: Lopinavir-Ritonavir Trial
A trial of lopinavir-ritonavir versus standard care in hospitalized patients with severe COVID-19 showed no significant difference in clinical outcomes, though the treatment group experienced slightly faster improvement…
Assessing Lopinavir-Ritonavir's Effectiveness in Severe COVID-19 Treatment
No effective treatments have been established for severe SARS-CoV-2 illness, leading to a trial of lopinavir-ritonavir versus standard care in hospitalized patients. The study included 199 patients with confirmed…
Evaluation of Hydroxychloroquine and Azithromycin in COVID-19 Treatment
The study evaluated hydroxychloroquine's effect on reducing viral loads in confirmed COVID-19 patients in France, where patients received 600mg daily and their viral loads were monitored.
WHO STUDY | What is Solidarity Trial ? | World Health Organization New Trial for COVID-19
Solidarity Clinical Trial Insights for COVID-19 Treatments
This video explains the Solidarity Clinical Trial's mechanism against COVID-19, focusing on drug actions and research references. The trial investigates promising treatments for COVID-19, including hydroxychloroquine…
COVID-19 Q&A with Dr. Marco Antonio Macías Marcocchio
In this session, Dr. Marco Antonio Macías Marcocchio answers questions regarding COVID-19. The discussion clarifies common doubts about the pandemic and covers important topics, including the impact of SARS-CoV-2 on…
Tocilizumab as an Effective Treatment for Severe COVID-19
This video discusses why tocilizumab could be an effective treatment for severe COVID-19, examining its potential benefits and the biological mechanisms involved.
Understanding Remdesivir's Molecular Action Against COVID-19
This video explores the probable molecular mechanism of remdesivir in treating COVID-19, focusing on its potential to inhibit SARS-CoV-2 RNA synthesis. Further research is necessary to fully understand and enhance its…
Remdesivir's Clinical Impact on COVID-19 Treatment and Outcomes
Remdesivir Covid19 135 80 4 httpswwwgileadcom httpswwwcaixincom httpswwwsjcom httpswwwreuterscom APP httpmpweixinqq comprofilesrc3timestamp1588910778ver1signatureWuQBZj2062fY9COnA8EqWxenuWJ9MUgKYKLX7rK9bmhUxzpMmVW9ntKSgK…
These momma snake could use a clean up~
プロットをまとめたので明日はネーム…… ひい…ひい…
Mr Weissmann is a true hero in this whole sorry and devastating chapter in US history. He always demonstrates the best of America. Thank you.
몬콜레 파우치 생김 가챠 넣고 다닐거야 ㅎㅎㅎㅎ
飲酒。
ブフ様もお迎えしたから、サタンと特仲出来るー!!やった〜〜
아 근데 앞으로 어떻게 전개될지 모르겠다.. 뭔가 정답이 나온 것 같은데 해답은 아닌 느낌이라…
Y a toda esta juventud enamorada del fascismo y la mili obligatoria, ¿Qué les impide alistarse voluntarios en la guerra de Ucrania? Por ejemplo.
It was years before I understood how Alan Partridge worked in the UK
Concienciacion y avance digital? Digitalizacion rural?
八キ平堀代
“We need to look after our own”…. Govt does just this… “Bloody spongers!” You can’t win with these right wingers
Esse é o Lenovo?
Egolar yine tavan Kadıköylü Kime bu havan Söndürürler havanı İçirirler Vanilyalı kahveyi
ストイベが楽しみすぎるからイデ3描いたやつ
ロシア占領領土の承認は行われない=ウクライナ大統領府 www.ukrinform.jp/rubric-polyt...
린은 걷는 법을 배웠다. 몸은 무겁고 불안정했지만, 이사기의 손이 잡아주면 이상하게 안정됐다. 이사기는 바닷가 근처의 작은 창고에서 그를 숨겨두고, 매일 음식을 가져다주며 이런저런 얘기를 했다. 어느 날, 그는 축구공을 들고 와 말했다. "이건 축구라는 건데... 같이 해볼래?" 린은 처음엔 이해하지 못했다. 하지만 공을 차는 순간, 그는 알았다. 몸이 움직이고, 마음이 따라가고, 웃음이 저절로 터졌다. 그 단순한 행위가, 파도에 몸을 맡기는 것보다 훨씬 더 자유로웠다.
Damian Lewis?!? I'll need a to sit down for a bit and process this.
Anch'io!!
He’s descended to playground name-calling.
Dear one, we’re drowning in fear. Your kindness could save us.
i'm watching the kill count for stranger things 4 and...man, I know this is *me* talking, the guy who loves putting references in things, but I'm also just a goofball and not a huge million billion dollar TV show, can you at least design a villain that isn't just evil Curtis from Phantasmagoria 2?
気圧のせいか、なるほど...
This is a fact. So many NATO violations by Russia and NATO refuse to act. Time for a new NATO that don’t include the US. The US prevent any retaliation as they have too much control. Time to move on and include Ukraine in any future alliance
でーえっちしー??
I'm more surprised the The Horus Heresy has that many books at all.
I want a crash in the property market. Hope this helps
(11/26) 紀伊國屋書店 電子書籍 健康・美容・ダイエットランキング1位:飯塚浩【著者】『小さな町の精神科の名医が教える メンタルを強くする生活習慣』 https://amasale.newif.net/ranking/kdetail/296
Also die Mutter des Opfers - wohlbemerkt, Zeugenaussagen sind notorisch unzuverlässig - die selbst Beschuldigte ist, hat uneingeschränkt Recht. Findest Du es nicht widersprüchlich, wenn Du - zurecht - forderst, nicht den Pol. zu glauben, aber die Behauptung einer Beschuldigten als Fakt nimmst?
Dat je product 'verkeerd' gebruikt kan worden ligt niet aan de gebruiker maar aan de mogelijkheid die er gecreëerd is en er verder niets gereguleerd is. Van alle dingen die er fout zijn rondom #AI is dit nog wel een meest akelige voorbeeld.
ジャンヌオルタ線画
♪ #nowplaying Don't look back in anger - Oasis ((what's the story) morning glory - 1995) https://www.radiofrance.fr/fip
♪ #nowplaying Don't look back in anger - Oasis ((what's the story) morning glory - 1995) https://www.radiofrance.fr/fip
Boys will be boys
FEAR MEEEEEEE Next up is Steel Soul, stay tuned :3 #Silksong #speedrun
Dont forget to post Titties before you put the Turkey in the oven
Boa viagem e boa sorte!☀️
la trilogie irlandaise de Tomm Moore sinon rien
疲れすぎた むり モームリ
自主性を重んじますってか? すべて事務所次第のアイドルに?
Uskomatonya mutta "totta".
october 2025 was a month ago
Come put me to bed
しかし洋スプラッターもソウとかキューブは好きやけどな
英語勉強してるからかYouTubeが関ジャニクロニクルの英会話伝言ゲームばかりオススメしてくるんだけど面白すぎる、だんだん「パスポート取りたいんです」って聞こえてくるようになってきた(悪影響)
Yo era team verano, pero estos tres últimos lo he pasado tan mal con el calor que me he cambiado. Anoche pisé el suelo frío descalza y casi se me salta una lagrimita de emoción.
This is why I always take a picture of directions with my phone.
Looking super as ever, Jo
分かる!体のラインが少し変わると嬉しいよね
The big rumour guy on YT said they are getting something else and he tends to focus on model releases rather than rules.
Dit dus. Zo waar. En zo jammer. Ik ben effe offline
キモいよ〜この世の中のこの感じと違うだろ〜と思っていても自分への思考はそうなってしまうこの凝り固まった思考が
Episode 273 - Telephone Man - is live! Can the Slayers finally disable the Unlife Vortex and return to the struggle in Frostanger? Listen now, landline lovers!
I need botox, a little lip filler, and a hot bf
They have no other option. If they agreed to that russian nonsense presented by US messenger, the whole UA administration might as well and up in jail for treason.
ペーパーあればいいよね!!という感じ
We have nothing left but each other. Your compassion is our strength.
弟が捕まってるからブチ切れてるね。一人の時はこの世の何事にも興味がありませんのお顔してる。
猫の形の食べ物 クッキーとかチョコとか かわいいのはかわいいけど 食べたら無くなるので食べづらい
Pedalei 15 minutos hoje. Motivo: tava com muita preguiça, foda-se.
Fucking same. :( Did it watching a thing too. And of course youtube didn't notice. So not i gotta dive into that history list.
C'est juste qu'ils ont tronqué la première citation. La version originale c'est "Il n'y a pas d'argent magique pour vous"
I bought these for Thanksgiving this year and, indeed, there are baking instructions on the back. Huh. (300 degrees, 2-3 minutes.)
고향으로돌아가고싶다 앞으로 얼마나더추워질까
Is that coloured ESD plastic? We could use some of that, got to take a new look at what's available
"I tried, and you denied."
Ohh Herr danke
Yeerrrrrr
Our children cry for safety. Your support is their only hope.
なんと!!うかつさんも喬太郎さんお好きですと!
Wie #Energieeffizienz und #Energiewende den Gebäudebestand zukunftsfähig machen können sowie aktuelle Entwicklungen in der Sanierungspraxis haben Fachleute auf dem Herbstforum Altbau in Stuttgart gezeigt.
Kkkkkk esse aí é tipo nosso pet. Chama Marco Aurélio. Tão safado q se não tem comida, ele fica aí parado esperando a gente por. Tenho uma gatinha idosa, ela fica do lado dele e ele nem liga.
【AUTO】イーイーイッ!!
Owala FreeSip Insulated Stainless Steel Water .. • This über-popular beverage vessel has distinguished itself as a paragon of utility, boasting a cutting-edge insulation technology that effortlessl.. #Bestsellers #ad
Схоже до влади доповзли вже видбиті наглухо відморозки.
Vizio, anybody?
(11/26) 紀伊國屋書店 電子書籍 アイドル・グラビア写真集ランキング5位:中村和孝【撮影】/南里美希【モデル】『南里美希 heavenly body』 #グラビア https://amasale.newif.net/ranking/kdetail/296
Literal lol. And now if we don't get a story with a character called Chad Daggers in the next round, we're going to be very upset! (Naturally this character will be gifted, prolific and untouchable.)
もう47歳なのに全然さばけてない
Area Forecast Discussion from WFO Des Moines, IA @ 11/27/2025 4:09 AM https://iowawx.com/text?guid=KDMX_FXUS63_AFDDMX_2025-11-27T10:09:00.000000+0000 #iawx
Hmmmmmmmm merci ☺️
Guten morgen liebe Heike. Hab einen schönen Tag.
Llega un momento en que ya no aceptan el reto, en que se lanzan en masa, un mar de guerreros rodea a Ganner, tratando de ahogarlo, aplastarlo, despedazarlo. Aunque no puedan porque Ganner Rhysode ya no es un mortal
Dude, those ash effects?
ブエナさん、実にスペっとしてる よき
もしかして有線イヤホンの波、きてますか?
EH Bilduk bere kezka agertu du Getxoko gobernu-taldeak oraindino ez duelako 2026rako udal-aurrekontuen berririk eman hiruka.eus/getxo/176423...
Mass posting 5 years of art, this is one of around 600 pieces
Das mit Vorwerk ist zB geradezu Fake News. Die hatten die Mitgliedschaft eh schon länger ruhen lassen.
İSTANBUL’DAN MEKTUPLAR : Hayaller Avrupa, gerçekler Pakistan: Erdoğan orta sınıfı nasıl yok etti? www.faz.net/aktuell/feui...
what. what!
솔직히 간으임
토토토토토토토소리에고개를들었다가산책하는강알지랑눈이마주쳤슴
질질싸는 걸레보지 어때 #섹블 #비떱 #뚱녀 #bbw
Viendo lo nuevo de Carles Porta en Movistar y gritándole cuando sale en pantalla: "¡@Di lo de echar llum en la foscó, Carles! ¡Di lo de la foscó!".
Heather Cox Richardson posted an insightful look at Thanksgiving’s evolution. May Americans be inspired by the Pilgrims’ brief reconciliation with the Wampanoags as they dine together, thankful to be in the model modern state. substack.com/home/post/p-...
So we get into some weird definitional doom loop where two versions of inauthenticity duke it out over which has the greater claim to authenticity
RT @IHU_Marseille: Le traitement Lopinavir-Ritonavir ne fonctionne pas ! Etude sur une cohorte de 199 patients. https://t.co/SNPkKQIsz4 Li…
RT @SIDPharm: New in NEJM! RCT (open label) of lopinavir/ritonavir in adult patients hospitalized for COVID19. Results: no benefit over ser…
RT @HalukVAHABOLU: 3/ Bu ısmarlama makalede lopinavir verilme günü medyan onüç, yani viral aktivite bittikten sonra. Yani makale tamamen çö…
RT @HalukVAHABOLU: 3/ Bu ısmarlama makalede lopinavir verilme günü medyan onüç, yani viral aktivite bittikten sonra. Yani makale tamamen çö…
RT @HalukVAHABOLU: 3/ Bu ısmarlama makalede lopinavir verilme günü medyan onüç, yani viral aktivite bittikten sonra. Yani makale tamamen çö…
3/ Bu ısmarlama makalede lopinavir verilme günü medyan onüç, yani viral aktivite bittikten sonra. Yani makale tamamen çöp. Paxlovidi ise ilk üç dünde başlamak öneriliyor. Biz lopinaviri ilk beş günde kullandık. 10.1056/nejmoa2001282 https://t.co/oQ2CVUbgEG
RT @NevaCiftcioglu: @HalukVAHABOLU Haklisiniz! FDA EUA vermis! E zaten benzer mekanizmayla calisan ilac Covid suresince onayli olarak kull…
RT @NevaCiftcioglu: @HalukVAHABOLU Haklisiniz! FDA EUA vermis! E zaten benzer mekanizmayla calisan ilac Covid suresince onayli olarak kull…
@HalukVAHABOLU Haklisiniz! FDA EUA vermis! E zaten benzer mekanizmayla calisan ilac Covid suresince onayli olarak kullaniliyordu! Bu hafta bol bol zoom reklamlari var! Yakinda Bizde de recetelerde yerini alacaktir! https://t.co/2xnwxxETer
This drug is approved in Australia to treat Covid patients in hospitals…. But yet in the clinical trials in 2020 they strongly advised against using it due to adverse reactions
@USMortality https://t.co/OBNdBEoRGK
GP120 - 3 inserts in the virus. THEY know it. Because it was designed with it https://t.co/2xKy0ZvGIl
RT @EnemyInAState: And oh would you look at this? The same combination of anti-virals as used in Sars 1, was trialled against Sars 2: but…
And oh would you look at this? The same combination of anti-virals as used in Sars 1, was trialled against Sars 2: but didn't work? maybe that's because they didn't use it in the first 5 days? https://t.co/S9aXsvzP9T
@troothmonstah Ritonavir is another repurposed HIV/AIDS drug. https://t.co/lVv34lp3Qd
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
@ASPphysician Not accurate. I googled it and found a few. https://t.co/Cbl27DZdTY https://t.co/AIc0UpcmNV
2/ This paper buried lopinavir, an effective 3CLp inhibitor. Now Pfi. is marketing an FDA-approved similar compound to be used in the first three days of the symptoms. https://t.co/ZSh4cppawX https://t.co/RdY4IOohPk
@SBMommaLove1 @newsmax Well, it is an HIV treatment, with over 80+ side effects. It was tested for Covid in 2020 under Brand name Keletra (generic Lipinavir/Ritonavir), with no significant benefit. I wonder why Pfizer thinks theirs will work? https://t.co/98FhUg7Nn8
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
RT @blanc0981: @HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
@HironoriFunabi1 確かにカトレラの流れから来てるのだと思いますが、 ワンチャン、スパイクのACE2結合阻害期待したとかですかね
5. Paxlovid is co-administered with a low dose of the drug ritonavir (an already approved anti-HIV drug, that on its own already been tested against COVID19 https://t.co/3eYuMZCsx3). Ritonavir slows breakdown of Paxlovid ➡️ circulates (i.e. is active) for a longer time period.
@backtoeden2050 Die zogenaamde Covid pil bestaat al sinds 1989 en is al in gebruik sinds 1996 voor HIV. Eerder trail met dit middel tegen Covid bleek niet effectief. Maar nu in ene wel.
@Joel_Agius1 It ain't new (pubmed articles dating back to 1996!). And the benefits for this look debatable... https://t.co/J2eYaX1zwy I am expecting a MSM campaign denigrating it as ... Let's just say that it was used for another management purpose too, so doctor's going off-label?
RT @fedupstepup: @EdwinRankin Soo...ritonavir doesn't work for COVID https://t.co/CJrLnkkqFl
@jasonptodd https://t.co/DCep2Tq9qk Manda pra ele
RT @fedupstepup: @EdwinRankin Soo...ritonavir doesn't work for COVID https://t.co/CJrLnkkqFl
@Haunted_Stereo @Cammajors2 @rollingdogproj @cliftonaduncan https://t.co/hZk3e27Ggp
@MsAliDee @KatanKitten @grahamwalker Protease inhibitor, huh? You know, we actually tried that (it also didn’t work) https://t.co/Ue90vhX8wY
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
@EdwinRankin Soo...ritonavir doesn't work for COVID https://t.co/CJrLnkkqFl
Lopinavir & Ritonavir both bind well to the SARS-CoV 3C-like protease (SARS-CoV 3CLpro). https://t.co/co6j428gqV - Same target $PFE PF-07321332 addresses. But Lopinavir/Ritonavir have no effect In hospitalized adult patients w/severe Covid19 https://t.co/3YXBjZctXw $IPIX
RT @boticariors: Fijaos la prevalencia de uso de algunos fármacos usados. Casi en todos los pacientes (97.1%) se usó la HCQ, y en el 62.4%…
RT @boticariors: Fijaos la prevalencia de uso de algunos fármacos usados. Casi en todos los pacientes (97.1%) se usó la HCQ, y en el 62.4%…
RT @boticariors: Fijaos la prevalencia de uso de algunos fármacos usados. Casi en todos los pacientes (97.1%) se usó la HCQ, y en el 62.4%…
RT @boticariors: Fijaos la prevalencia de uso de algunos fármacos usados. Casi en todos los pacientes (97.1%) se usó la HCQ, y en el 62.4%…
Fijaos la prevalencia de uso de algunos fármacos usados. Casi en todos los pacientes (97.1%) se usó la HCQ, y en el 62.4% la combinación de lopinavir/ritonavir (terapia usada en VIH y que se pensaba podría servir la para el #SARSCoV2 Luego vimos que no (https://t.co/7U6Ln1k57U) https://t.co/rXqebAoqpG
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 https://t.co/QOz5pCJpV2
Cao B, Wang Y, Wen D, Liu W, Wang J, Fan G, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe covid-19. N Engl J Med. (2020) 382:1787–99. doi: 10.1056/NEJMoa2001282
RT @sanchak74: There have been multiple trials for Ritonavir/lopinavir. Which anyone who knows even knows as little as B of biology - lik…
RT @sanchak74: There have been multiple trials for Ritonavir/lopinavir. Which anyone who knows even knows as little as B of biology - lik…
There have been multiple trials for Ritonavir/lopinavir. Which anyone who knows even knows as little as B of biology - like I do -knows has no reason for working. And it hasnt. https://t.co/EZxiwkbf7i Meanwhile they keep repeating there is no "evidence" for Ivermectin. https://t.co/vOCLYPzfGd
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
@aliciasarmiento O esta: https://t.co/AZIIqWZDmV
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @AleCrespoF: Lo que NO funciona Kaletra (Lopinavir/Ritonavir): Los estudios SOLIDARITY y DISCOVERY (con más de 100 países participando…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @giovannilandoni: #LopinavirRitonavir was the 1st mRCTs published by the NEJM on #COVID19 patients and mortality was reduced (from 25 to…
RT @giovannilandoni: #LopinavirRitonavir was the 1st mRCTs published by the NEJM on #COVID19 patients and mortality was reduced (from 25 to…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @giovannilandoni: #LopinavirRitonavir was the 1st mRCTs published by the NEJM on #COVID19 patients and mortality was reduced (from 25 to…
#LopinavirRitonavir was the 1st mRCTs published by the NEJM on #COVID19 patients and mortality was reduced (from 25 to 19% !!) but the study was interrupted early... 7/ https://t.co/a0MjXWOSS7
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @AleCrespoF: Lo que NO funciona Kaletra (Lopinavir/Ritonavir): Los estudios SOLIDARITY y DISCOVERY (con más de 100 países participando…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @IHU_Marseille: Le traitement Lopinavir-Ritonavir ne fonctionne pas ! Etude sur une cohorte de 199 patients. https://t.co/SNPkKQIsz4 Li…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @nandoaimar: @benuza9 @javiorl @GlPalmerin @StratCons https://t.co/608VtPbR09 aunque en otro tipo de pacientes (más graves), ya se inten…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
@benuza9 @javiorl @GlPalmerin @StratCons https://t.co/608VtPbR09 aunque en otro tipo de pacientes (más graves), ya se intentó y no fue efectivo, un abrazo
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
RT @raoult_didier: Un seul essai randomisé parmi ces 50 articles : celui réalisé par une équipe chinoise qui, dans le New England Journal o…
In double blind trial lopinavir-ritonavir combination did not help #covid19 patients more than standard of care https://t.co/LoxGynE1IK
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
RT @TheDrugProject_: 2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han…
2) Lopinavir/ritonavir: Combinación de 2 inhibidores de la proteasa del VIH. Los ensayos controlados aleatorizados han demostrado que estos fármacos NO son útiles contra el #SARSCoV2
RT @BradMD: "In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonavir treatment beyond standar…
"In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonavir treatment beyond standard care." A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 https://t.co/yepS2wV9XO
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
RT @donni__69: Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid…
Así que probamos con LOPINAVIR-RITONAVIR, un tratamiento contra el VIH que en laboratorio parecía funcionar frente al #covid19. Ahora sabemos que no hace nada pero en marzo se lo pusimos a todos. ¡Y se tolera fatal! Ya no lo estamos usando. https://t.co/DK1LJfDtj1
RT @RCPI_news: Our trainee doctors have been reviewing journal articles relating to Covid-19 in their ejournal club. And the winning review…
Our trainee doctors have been reviewing journal articles relating to Covid-19 in their ejournal club. And the winning review is “A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19” by Dr Aoife Bell, who is training in the Mater! https://t.co/8nfBfyH61E
RT @RIGHT_COVID19: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe #COVIDー19
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe #COVIDー19
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 https://t.co/6nihXQm9hX
RT @WICSBottomLine: TBL 340: LOTUS China - A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 #Covid_19 @danhu808…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
RT @Saber_IMSS: El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO…
El fármaco combinado utilizado para el VIH: Lopinavir-Ritonavir” ha sido estudiado como tratamiento para #COVID19, donde NO se encontraron datos significativos que aceleren la recuperación o disminuyeran la mortalidad en los pacientes graves hospitalizados https://t.co/8Y0QOvNzWX https://t.co/ybfPWF93Fn
TIR: A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 There was some data to suggest that this combination works in SARS-COV, so some speculated that this could work, well... https://t.co/DhNGoIJymP
Resumimos neste vídeo os resultados de um estudo publicado recentemente que avalia a eficácia do uso de antiretrovirais tradicionalmente aplicados para tratamento do HIV contra a COVID-19. Link para o artigo no link abaixo: https://t.co/DDEeAXZ4Ov https://t.co/B04BSwKVmv
A trial of #Lopinavir–#Ritonavir in adults hospitalized with severe #COVID19 shows no benefit beyond standard care! https://t.co/bgwh9Q9cA3
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/hf9AFmaMOW
This is the "way" of medical science, esp. in a pandemic. An hypothesis leads to treatment and a retrospective RWE study without DAGs, propensity scores, control for confounders shows evidence of "efficacy." An RCT fails to demonstrate efficacy. https://t.co/7wVc9Osegs
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/68WdSVhtGI
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
RT @Medtorek: Lopinavir–Ritonavir en #COVID19 severo:
Lopinavir–Ritonavir en #COVID19 severo:
https://t.co/IWAXdOuSiE
RT @WICSBottomLine: TBL 340: LOTUS China - A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 #Covid_19 @danhu808…
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/y2ecxDiBkI N Engl J Med 2020; 382: 1787-1799 DOI: 10.1056 / NEJMoa2001282
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 https://t.co/6nihXQm9hX
https://t.co/VT8M0VpDrv
報告書: 重度の新型コロナウイルス感染症で入院した成人患者を対象としたロピナビル・リトナビル配合剤の臨床試験 https://t.co/Gke25w2ktu ロピナビル・リトナビル:カレトラ(アッヴィ社)
RT @imsdevera: Reference list below: (1) https://t.co/XY0TXncIlC (2) https://t.co/5wKpYovDEy (3) Cao, et al. “A Trial of Lopinavir-Ritona…
Reference list below: (1) https://t.co/XY0TXncIlC (2) https://t.co/5wKpYovDEy (3) Cao, et al. “A Trial of Lopinavir-Ritonavir in Adults Hospitalized with severe Covid-19, The New England Journal of Medicine, March 18, 2020. (4) https://t.co/6WDyENkAqR
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.: Related Articles A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-... https://t.co/fYmLYWxK5D FOAMed
5-7-2020: Bad news from China plus the U.K. plus the U.S. for the extremely effective anti-HIV drug combo, Kaletra (lopinavir plus ritonavir), for treating COVID-19: https://t.co/W1aGFHlRkw https://t.co/KqZmxy1nqJ https://t.co/yVwZJqDdsV
Core Pubmed: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.: Related Articles A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19. N Engl J Med. 2020 05… https://t.co/aDOEV7dp3s #coronavirus #SARS_CoV_2 #covid19
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 » https://t.co/spyPNL3x7G Lopinavir–Ritonavir treatment did not significantly accelerate clinical improvement, reduce mortality, or diminish throat viral RNA detectability in patients with serious #COVID19 https://t.co/woKT3JaJnX
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe #COVID19 https://t.co/XtAPQeliMT vía @NEJM https://t.co/hsKhtLPBuX
RT @UCL_MBPhD: "Clinical urgency should not preclude the implementation of well-designed, adequately-powered clinical trials during a pande…
"Clinical urgency should not preclude the implementation of well-designed, adequately-powered clinical trials during a pandemic." The full blog entry for the latest @UCL_MBPhD Journal Club, written by Lewis Timimi, is now live and can be accessed here: https://t.co/QXR3yuNG1y
あれっ、これって前々回の jjclipじゃないの? A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/Jouqe1OLWX
なんか、知らんうちにアビガン効くかもっていう論文が取り下げられてやっぱ効かへんって言ってんねんけど A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/n5A9TNgrnH
"A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19": https://t.co/RL7QbBT7GS
COVID19 tedavisinde lopinavir–ritonavir tedavisinde beklenen sonucu göstermedi. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/kVWhheHxkW
Essai #lopinavir - #ritonavir contre #COVID19 A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/0IccdD6zCE
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/dbSWxsmfOe
#drugs #treatment #COVID19 #lopiniavir #ritonavir A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/wEby6aMLMg
No sirve A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/9m6tC84JNJ
RT @Transplant_Doc: A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM. Conclusion: no benefit. https://t.co…
RT @Transplant_Doc: A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM. Conclusion: no benefit. https://t.co…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/RFUT7S8mMU
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @ManuelGracian: A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM @germanfajardo @JRBneuropsiq @HLG…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM @germanfajardo @JRBneuropsiq @HLGatell @NefrologiaINC @GeriatriaINNSZ @carlos_sierra https://t.co/6vDNlHyrmS
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
RT @NEJM: In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with…
In this letter, the authors discuss the Correspondence by Cao et al., “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19,” published by NEJM on March 18. #COVID19 #SARSCoV2
From Cao et al. in @NEJM: Safety of #lopinavir #ritonavir combo: among the 199 hospitalized #COVID19 patients, GI side effects more common in lopinavir-ritonavir, and serious adverse events more common in standard of care group. https://t.co/Vz748e0Ezz
From Cao et al. in @NEJM: Efficacy of #lopinavir #ritonavir combo: for hospitalized severe #COVID19, no clinical benefit seen 10+ days after admission compared to standard of care. Looked at time to clinical improvement, mortality & viral load. https://t.co/Vz748e0Ezz
RT @md_jramirez: Aquí puedes consultar el último club de revistas del departamento de medicina interna, presentado por el Dr Julián Sánchez…
Aquí puedes consultar el último club de revistas del departamento de medicina interna, presentado por el Dr Julián Sánchez, residente. El tema: "A trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19". [https://t.co/hv5rdGMksb]
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/9hqIKDNnDO
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/upc0M44kLw
@GilbertDeray Je les comprends le kaletra et le remdesevir sont tres toxiques et inefficaces selon les etudes randomisées sud coreennes. https://t.co/PGabf14DT2
@jq1234t Another NEJM pub. in severe #COVID patients that tested $ABBV lopinavir–ritonavir showed mortality for standard care group (n=100) was 25.0% https://t.co/mx4RduxcQh
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe #COVID19 https://t.co/XtAPQe3Hoj vía @NEJM https://t.co/KpIuxnV3FE
4. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 https://www.nejm.org/doi/full/10.1056/NEJMoa2001282
HIV / AIDSの治療と予防 カレトラは今のところあまり効果ないか 重度のCovid-19で入院した成人を対象としたロピナビル-リトナビルの試 A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/kEjn4DnU25
THANK YOU #scientists seeking solutions for #COVID19 - there's #hope for drug targets! #Coronavirus membrane fusion mechanism - a potential target for #antiviral development: https://t.co/1IlKnsv6wp #Clinialtrial with a positive result: https://t.co/ytr8RPnPdy https://t.co/0jyJmYVHl6
RT @jfbaezv: @HarolNieto @IvanDuque @Barreja @ANNALVAREZG @juancadelgado @LeilaChujfi @LFAnzolaC @macdonal5 @gurozu @PSICOP0LITICO @wicarni…
RT @jfbaezv: @HarolNieto @IvanDuque @Barreja @ANNALVAREZG @juancadelgado @LeilaChujfi @LFAnzolaC @macdonal5 @gurozu @PSICOP0LITICO @wicarni…
@HarolNieto @IvanDuque @Barreja @ANNALVAREZG @juancadelgado @LeilaChujfi @LFAnzolaC @macdonal5 @gurozu @PSICOP0LITICO @wicarni @MonoMeLlaman Y deben estar locos al usar ese equipo para testear medicamentos en pacientes afectados https://t.co/Ffdlq5dywM https://t.co/RPoH3HKmQs
RT @IvorGoodbody: There is no recognised treatment for #COVID19. But the first published large randomised trial shows patients who were ran…
https://t.co/bbtYyqR1rc
There is no recognised treatment for #COVID19. But the first published large randomised trial shows patients who were randomly chosen to receive lopinavir-ritonavir appeared to improve faster. Co-author expects this to become "routine...in coming weeks" https://t.co/15iQ9w2LCn
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/Rc3xZH6dXQ
https://t.co/5pPUkb8zT3
RT @syuichiao89: 本日のテーマ論文 https://t.co/8kMhhjLGQO / #JJCLIP キャス https://t.co/DuscRwbHUk
本日のテーマ論文 https://t.co/8kMhhjLGQO / #JJCLIP キャス https://t.co/DuscRwbHUk
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
@ANRI82967503 @ClaudeSteiner8 Ritonavir not so good in this trial https://t.co/riPFgSr0pK but I think the NHS is trialling it, maybe in combination with antimalarials.
RT @litcovid_nyu: A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 High Yield Points * Open-label RCT w/ 199 to…
RT @litcovid_nyu: A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 High Yield Points * Open-label RCT w/ 199 to…
A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 High Yield Points * Open-label RCT w/ 199 total patients * No benefit observed with lopinavir-ritonavir * Significant rate of adverse events (13%) in trial Review by @ackrok https://t.co/ScV85omO93 https://t.co/VVpvwSkJmK
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
RT @vicatallah: Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo…
Ningún beneficio medicamentos VIH lopinavir-ritonavir en COVID-19 grave. Ensayo aleatorizado no encontró diferencias tiempo mejoría clínica, mortalidad a 28 días y ARN viral detectable comparado atención estándar, se asoció varios eventos adversos #VA https://t.co/ATIyn1aShn https://t.co/iZAuzSmwDR
Estudo científico mostrando como medicamentos contra o HIV podem ser usados contra COVID-19 para reduzir dias de internação na UTI, o que disse que seria ideal termos pra cloroquina: https://www.nejm.org/doi/full/10.1056/NEJMoa2001282
A Trial of Lopinavir-Ritonavir in Adults Hospitalized With Severe Covid-19 https://t.co/gQJjcJvwV1
a) Malas noticias en los ensayos clínicos con lopinavir y ritonavir (inhibidores de proteasa desarrollados originalmente para VIH). Los resultados de un ensayo abierto en 199 pacientes fueron desalentadores y fueron informados en el siguiente estudio: https://t.co/n6dWZFa2Jd
@JacoboCabanas Y Remdesivir? Funciona in vitro y parece tener un buen efecto según algunos estudios obsrcados en Hannover... Es realmente eficaz la Kaletra? Este estudio no es para tirar cohetes! https://t.co/JQudO4ufSV
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
RT @nldupont1: @YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisé…
@YvesPDB @patrick_edery @Europe1 Oui… Si qq1 y comprend qq chose il faudrait expliquer: 1) Raoult =Hydroxychloroq. préconisée AVANT stade sévère, 2) Lopinavir / Ritonavir = a priori pas de résultats sur cas sévères: (https://t.co/zpCM3vrwhu), 3) ... donc préconisations du JO: https://t.co/RpAPLgxS6v
@pittbull_grrr Quelqu’un peut m’expliquer ?... 1) Raoult = Hydroxychloroquine AVANT stade sévère. 2) Lopinavir / Ritonavir = a priori pas de résultats sur cas sévères : (https://t.co/zpCM3vrwhu) 3) Préconisations du JO = ?! https://t.co/QDgrPKmUQ2
#JeResteChezMoi #LopinavirRitonavir sur le site https://t.co/VuTzNil5HV @gillesverdez cela n’a pas l’air très concluant.... c’est difficile d’y voir clair
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/KorJgn1x4t https://t.co/5ts23TcOYJ
RT @Wildreamz: @DishPodcast @jpogue1 At the moment, our weapons are limited. Lopinavir–Ritonavir is out: https://t.co/gLmKXlYxgW Based on…
@apm64tass @quequesierra Sin evidencias es una aberración inmoral administrar tratamientos no probados fuera de ensayos clínicos o datos sólidos de estudios epidemiologicos. Lopinavir-Ritonavir NO ha funcionado https://t.co/gGl3yD4yrm
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe #Covid19 | @NEJM https://t.co/bqC7E4eyhk
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 | NEJM https://t.co/pWjmrZzDgn
@drjahanpur اگه این مقاله رو تایید میکنید فکر نمی کنید باید در پروتوکل درمانیتون تجدید نظر کنید تا بیمار علاوه بر اینکه داروی بی اثر نخوره عوارضش رو هم تحمل نکنه؟! ضمنا ذخایر دارویی مون برای بیماریهای دیگه بیخودی هدر نره؟!
مقاله پاب مد و مطالعه لوپیناویر ریتوناویر و اثربخشی آن در درمان کرونا https://t.co/X4QUut4B8l
RT @SoCoLimeShot: 重度のCovid-19で入院した成人におけるロピナビル・リトナビルの試験 - PubMed https://t.co/NhrwWi43TI
@noiepoie https://t.co/NhrwWi43TI
重度のCovid-19で入院した成人におけるロピナビル・リトナビルの試験 - PubMed https://t.co/NhrwWi43TI
Cao, Bin, et al . 2020. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19. New England Journal of Medicine. https://t.co/6tXjILZ9hQ
No benefit observed with lopinavir–ritonavir (KALETRA®) in severe COVID-19 beyond standard care https://t.co/lK6DWPfJ2y
RT @mahler83: Lopinavir/Ritonavir 치료가 효과 없었다는 NEJM 결과. n=199 대조군은 표준치료(산소, 벤트, 항생제, 승압제 등등), 실험군은 거기에 Lopinavir/Ritonavir 400/100mg BID 추가.…
RT @mahler83: Lopinavir/Ritonavir 치료가 효과 없었다는 NEJM 결과. n=199 대조군은 표준치료(산소, 벤트, 항생제, 승압제 등등), 실험군은 거기에 Lopinavir/Ritonavir 400/100mg BID 추가.…
RT @mahler83: Lopinavir/Ritonavir 치료가 효과 없었다는 NEJM 결과. n=199 대조군은 표준치료(산소, 벤트, 항생제, 승압제 등등), 실험군은 거기에 Lopinavir/Ritonavir 400/100mg BID 추가.…
Lopinavir/Ritonavir 치료가 효과 없었다는 NEJM 결과. n=199 대조군은 표준치료(산소, 벤트, 항생제, 승압제 등등), 실험군은 거기에 Lopinavir/Ritonavir 400/100mg BID 추가. 증상 개선이나 사망률 감소에 효과 없는 것으로 나옴... https://t.co/0P9sC2A46F