Assessment of the Efficacy of Root Extract in Patients with Generalized Anxiety Disorder: A Randomized Double-blind Placebo- Controlled Trial.

Sara Fuladi, Seyed A Emami, Amir H Mohammadpour, Asieh Karimani, Ali A Manteghi, Amirhossein Sahebkar

April 2022

Synopsis of Social media discussions

The collective discussions express general support for the findings, with mentions of the extract's promise as an alternative treatment, as seen in comments calling it a 'safe and effective' option. The tone indicates a balanced curiosity combined with optimism about the potential implications for managing GAD, using words like 'promising' and 'support' to convey both interest and perceived significance.

A
Agreement
 Moderate agreement

Most discussions echo support for the research findings, with posts mentioning positive results and potential benefits of the extract.

I
Interest
 Moderate level of interest

Posts demonstrate moderate curiosity, with some highlighting the novelty of using herbal treatments for GAD.

E
Engagement
 Moderate level of engagement

Various posts delve into methodological aspects and potential clinical applications, showing a moderate level of involvement.

I
Impact
 Moderate level of impact

Several comments suggest the findings could influence future treatments or encourage further research, indicating moderate perceived impact.

Social Mentions

YouTube

2 Videos

Twitter

5 Posts

Metrics

Video Views

123,833

Total Likes

3,217

Extended Reach

140,204

Social Features

7

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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  • Сюрике Нсусами
    @dzhochchi (Twitter)

    @p0trachen0 @_elusive_joe_ А вот несколько ссылок тебе по стрессу и тревожности: ашваганда отлично работает на людях с с подтвержденными диагнозами, уровень кортизола не меняется, но меняется чувствительность к нему, снижаются симптомы усталости и общее восстановление организма https://t.co/cOEOLsI0bt
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    May 20, 2025

    1

  • Marion van Kempen
    @MvK_1234 (Twitter)

    Assessment of the Efficacy of Withania somnifera Root Extract in Patients with Generalized Anxiety Disorder: A Rand… https://t.co/kl16c7bzif
    view full post

    March 1, 2024

  • Canada RNA Biochemical Inc.
    @CanadaRna (Twitter)

    Ashwagandha Extract may be a Safe and Effective Adjunct Treatment for Patients with Generalized Anxiety Disorder https://t.co/5HRoc8wzRU https://t.co/Ys53NQUB86
    view full post

    November 29, 2023

  • OJSN
    @iamojsn (Twitter)

    https://t.co/V1qmxLrumL https://t.co/ODqA00Yzda https://t.co/5K7v3hW02Q https://t.co/NHrMzZQ66P https://t.co/PhSBQfCe8h https://t.co/Wkrr94ylfP https://t.co/ZhnhoGe39p https://t.co/a8NnbMsoxd
    view full post

    January 5, 2023

    3

  • Dr. LoBisco
    @DrLoBisco (Twitter)

    Assessment of Withania somnifera root extract efficacy in patients with generalized anxiety disorder: A randomized double-blind placebo-controlled trial https://t.co/IjlIOQ23Pt
    view full post

    April 12, 2021

Abstract Synopsis

  • This study investigates whether the root extract of Withania somnifera (also known as Ashwagandha) can be an effective alternative treatment for Generalized Anxiety Disorder (GAD), especially given the limitations of current medications, which often have high recurrence rates after stopping.
  • The trial involved 40 patients already on SSRIs who were randomly assigned to receive either the 1g daily root extract or a placebo for six weeks, with anxiety symptoms measured using the Hamilton Anxiety Rating Scale (HAMA).
  • Results showed a significant reduction in anxiety symptoms in the group taking the extract compared to the placebo, indicating that Withania somnifera root extract may help decrease GAD symptoms with potentially fewer side effects.