April 2022 PMID 32282308

Assessment of the Efficacy of Root Extract in Patients with Generalized Anxiety Disorder: A Randomized Double-blind Placebo- Controlled Trial.

Sara Fuladi, Seyed A Emami, Amir H Mohammadpour, Asieh Karimani, Ali A Manteghi, Amirhossein Sahebkar

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Mentions

Peak: 2 in Mar 2024

across 2 sources since Apr 2021

Extended reach

140,204

potential audience

Total likes

3,217

Video views

123,833

Mentions per month

Apr 2021 – May 2025

Where it's discussed

X / Twitter5 posts
YouTube2 videos

AI synopsis

What people are saying

The collective discussions express general support for the findings, with mentions of the extract's promise as an alternative treatment, as seen in comments calling it a 'safe and effective' option. The tone indicates a balanced curiosity combined with optimism about the potential implications for managing GAD, using words like 'promising' and 'support' to convey both interest and perceived significance.

AgreementModerate agreement

Most discussions echo support for the research findings, with posts mentioning positive results and potential benefits of the extract.

InterestModerate interest

Posts demonstrate moderate curiosity, with some highlighting the novelty of using herbal treatments for GAD.

EngagementModerate engagement

Various posts delve into methodological aspects and potential clinical applications, showing a moderate level of involvement.

ImpactModerate impact

Several comments suggest the findings could influence future treatments or encourage further research, indicating moderate perceived impact.

Abstract in brief

This study investigates whether the root extract of Withania somnifera (also known as Ashwagandha) can be an effective alternative treatment for Generalized Anxiety Disorder (GAD), especially given the limitations of current medications, which often have high recurrence rates after stopping.
The trial involved 40 patients already on SSRIs who were randomly assigned to receive either the 1g daily root extract or a placebo for six weeks, with anxiety symptoms measured using the Hamilton Anxiety Rating Scale (HAMA).
Results showed a significant reduction in anxiety symptoms in the group taking the extract compared to the placebo, indicating that Withania somnifera root extract may help decrease GAD symptoms with potentially fewer side effects.

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All mentions

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Сюрике Нсусами

@dzhochchi · X

May 20, 2025 · 1 like · 406 followers View post →

Marion van Kempen

@MvK_1234 · X

Assessment of the Efficacy of Withania somnifera Root Extract in Patients with Generalized Anxiety Disorder: A Rand… https://t.co/kl16c7bzif

Mar 1, 2024 · 22 followers View post →

Canada RNA Biochemical Inc.

@CanadaRna · X

Ashwagandha Extract may be a Safe and Effective Adjunct Treatment for Patients with Generalized Anxiety Disorder https://t.co/5HRoc8wzRU https://t.co/Ys53NQUB86

Nov 29, 2023 · 19 followers View post →

OJSN

@iamojsn · X

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Jan 5, 2023 · 3 likes · 14,955 followers View post →

Dr. LoBisco

@DrLoBisco · X

Assessment of Withania somnifera root extract efficacy in patients with generalized anxiety disorder: A randomized double-blind placebo-controlled trial https://t.co/IjlIOQ23Pt

Apr 12, 2021 · 970 followers View post →