May 2020 PMID 32375307

The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases.

Coralie Fontaine, Florent Morfoisse, Florence Tatin, Audrey Zamora, Rana Zahreddine, Daniel Henrion, Jean-François Arnal, Françoise Lenfant, Barbara Garmy-Susini

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Peak: 1 in Feb 2021

across 2 sources since Feb 2021

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Feb 2021 – Aug 2025

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AI synopsis

What people are saying

The discussions frequently praise the article for shedding light on how estrogens and related receptors influence vascular and lymphatic diseases, with phrases like 'game-changing insights' and 'new hope for treatments.' The tone combined scientific curiosity with recognition of the research's potential impact, using detailed references to molecular pathways and clinical implications to illustrate deep engagement.

AgreementModerate agreement

Most discussions acknowledge the importance of estrogen receptors in vascular health, supporting the article's relevance.

InterestHigh interest

The discussions show high curiosity, with many participants appreciating the focus on hormonal influences in disease mechanisms.

EngagementModerate engagement

Several posts analyze the scientific content, discussing signaling pathways and potential treatments, indicating active engagement.

ImpactModerate impact

There is recognition that understanding estrogen's role could influence future therapies for vascular conditions, though some see it as an emerging research area.

Abstract in brief

Estrogens play a key role in protecting women from cardiovascular diseases by promoting vasodilation, aiding in arterial healing, and preventing artery blockages, especially before menopause.
The effects of estrogens extend beyond blood vessels to the lymphatic system, where they influence conditions like lymphedema, through both traditional nuclear receptor pathways and rapid membrane-initiated signaling.
Estrogen receptors (ERs) are present in various vascular cells (endothelial, lymphatic, smooth muscle), and research using animal models helps to understand how estrogen and drugs like SERMs affect vascular and lymphatic diseases.]

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lymphaticpapers

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The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases. https://t.co/kucuEWnXns

Feb 6, 2021 View post →