Autoimmun Rev July 2020 PMID 32380316

Convalescent plasma in Covid-19: Possible mechanisms of action.

Manuel Rojas, Yhojan Rodríguez, Diana M Monsalve, Yeny Acosta-Ampudia, Bernardo Camacho, Juan Esteban Gallo, Adriana Rojas-Villarraga, Carolina Ramírez-Santana, Juan C Díaz-Coronado, Rubén Manrique, Ruben D Mantilla, Yehuda Shoenfeld, Juan-Manuel Anaya

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Peak: 5 in May 2020

across 4 sources since May 2020

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14,209

potential audience

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830

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May 2020 – Nov 2021

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Discussions show appreciation for scientific insights, with users mentioning mechanisms like virus neutralization and immune regulation, as well as acknowledging contributions from Colombian scientists; the tone combines curiosity and respect, reflecting positive reception and recognition of the research's relevance.

AgreementModerate agreement

Most comments seem to align positively with the article, especially highlighting convalescent plasma's potential mechanisms and benefits.

InterestHigh interest

The discussions demonstrate high curiosity about mechanisms and scientific contributions, reflecting genuine interest.

EngagementModerate engagement

Comments include recognition of scientific efforts and references to related articles, indicating moderate engagement.

ImpactModerate impact

The mentions of the publication and related research suggest acknowledgment of the work's significance, though not decisively transformative.

Abstract in brief

Convalescent plasma (CP) is considered a promising treatment for COVID-19 because it has been effective in past coronavirus outbreaks and may help neutralize the virus, regulate immune responses, and reduce complications like blood clots.
CP works by directly neutralizing SARS-CoV-2, controlling excessive immune responses such as cytokine storms, activating the complement system, and modulating blood clotting issues, all of which can improve patient outcomes.
The effectiveness of CP may be greatest when used early in hospitalized patients who are not critically ill, aiming to lower both morbidity and mortality associated with COVID-19.

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All mentions

Russian COVID-19 Vaccine Development and Convalescent Plasma Therapy

The video discusses Russia's advancements in COVID-19 vaccination, including approval and vaccination plans, as well as recent findings on convalescent plasma's potential benefits in severe COVID-19 cases, emphasizing…

Dr. Deepak Natarajan · Aug 7, 2020 483 views

Convalescent Plasma Therapy for COVID-19: Mechanisms and Efficacy

Convalescent plasma may help neutralize the virus, regulate immune responses, and reduce blood clot complications. Its effectiveness is highest when administered early to hospitalized patients to lower morbidity and…

mdStarvlog · Nov 12, 2021 347 views

ニューロドクター乱夢

@hichachu · X

Convalescent plasma in Covid-19: Possible mechanisms of action https://t.co/LAwhDTDEGL

Jul 20, 2020 · 4,258 followers View post →

habib boukhechem

@BoukhechemHabib · X

Convalescent plasma in Covid-19: Possible mechanisms of action https://t.co/nT9yRLqUDq

Jun 11, 2020 · 81 followers View post →

Krishan Maggon

@kkmaggon · X

Convalescent plasma in Covid-19: Possible mechanisms of action - ScienceDirect https://t.co/u2vc1qKpZH https://t.co/OuEwI4G5Si

May 12, 2020 · 1,000 followers View post →

Hospital Medicine Virtual Journal Club

@HMVJC · X

Convalescent plasma in Covid-19: Possible mechanisms of action.: Related Articles Convalescent plasma in Covid-19: Possible mechanisms of action. ... https://t.co/4mgAsASm1i FOAMed

May 10, 2020 · 630 followers View post →

Dra. Gabriela Zambrano

@gabizambranoMD · X

Convalescent plasma in Covid-19: Possible mechanisms of action https://t.co/EsdEJS7YIF

May 9, 2020 · 2,412 followers View post →

the paper link

@the_paper_link · X

Trend up+28: *Rojas M* et al (Autoimmun Rev) __Convalescent plasma in Covid-19: Possible mechanisms of action__ https://t.co/8Qdy6phAYZ

May 9, 2020 · 136 followers View post →

Fernando Suárez Obando

@FerSuarezMD · X

Otro artículo a la lista de aportes de científicos colombianos para entender y trata COVID-19 @JuanMAnayaC https://t.co/Uin51lqwOP

May 8, 2020 · 4,863 followers View post →