April 2020 PMID 32411700

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism.

Weiqi Hong, Fei Mo, Ziqi Zhang, Mengyuan Huang, Xiawei Wei

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Mentions

34
Peak: 2 in May 2020
across 4 sources since Apr 2020

Extended reach

225,971
potential audience

Total likes

5,304

Video views

167,397

Mentions per month

Apr 2020 – Jul 2024

Where it's discussed

  • News16 articles
  • X / Twitter10 posts
  • Blogs5 articles
  • YouTube3 videos

AI synopsis

What people are saying

Discussions highlight the potential of NMN as a therapy, with posts emphasizing its role in NAD+ metabolism and mentioning ongoing clinical trials. The tone varies from scientific references to hopeful statements, reflecting both curiosity and optimism about its impact on health and aging.

AgreementModerate agreement

Most discussions recognize the potential benefits of NMN and agree that it could be a promising avenue for treating age-related diseases.

InterestHigh interest

Users show high interest, evidenced by hashtags, mentions of clinical trials, and enthusiasm for the therapeutic possibilities.

EngagementModerate engagement

Comments include references to biochemical pathways and broader implications, indicating a moderate level of engagement.

ImpactModerate impact

Participants believe the research could significantly influence future therapies, though some discussions remain general or preliminary.

Abstract in brief

  • Nicotinamide Mononucleotide (NMN) is a promising molecule for treating various diseases because it plays a crucial role in maintaining NAD+ levels, which are vital for many biological processes like DNA repair, metabolism, and cell death.
  • Disruptions in NAD metabolism are linked to aging-related diseases such as diabetes, heart failure, Alzheimer's, and retinal degeneration, and supplementing with NMN has shown potential in improving these conditions in animal studies.
  • Ongoing clinical trials are exploring the safety and benefits of NMN, aiming to better understand NAD pathways for more effective therapies against age-related health issues.

Top posts

Most liked on X and Bluesky
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism https://t.co/ZMypNp69Mn #kahnchronicle

Sep 11, 2020 · 1 like · 32,258 followers View post →
rubic3n
@rubic3n · X

NMN Sirts https://t.co/uCinuaZpSA no flush

May 19, 2022 · 1 like · 1,777 followers View post →
tiktak
@taisukun · X

ニコチンアミドモノヌクレオチド:NAD +代謝を標的とすることによる多様な疾患の治療のための有望な分子 https://t.co/QlNtl7jYrL

Oct 22, 2020 · 1 like · 304 followers View post →
Thomas Maxwell
@T_A_Maxwell · X

@ChrisDungeon @geravoin https://t.co/agNx5dM7H8

Jan 5, 2022 · 1 like · 154 followers View post →
Nick Krontiris
@nick_krontiris · X

@RhyothemisP "The salvage pathway is the primary source of NAD+ in mammalian cells." https://t.co/x7z6VUoxBQ "...Rather than generated de novo, most NAD+ is recycled from NAM, NA, NR and NMN in the salvage pathway to maintain the cellular NAD+ levels" https://t.co/FJkVzj5A3i The article

Jun 13, 2023 · 19,137 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism: NAD+, a co-enzyme involved in a great deal of biochemical reactions, has been found to be a network node of diverse… https://t.co/E637Y3NIAY #celldevbio

Apr 28, 2020 · 3,809 followers View post →

All mentions

Nick Krontiris
@nick_krontiris · X

@RhyothemisP "The salvage pathway is the primary source of NAD+ in mammalian cells." https://t.co/x7z6VUoxBQ "...Rather than generated de novo, most NAD+ is recycled from NAM, NA, NR and NMN in the salvage pathway to maintain the cellular NAD+ levels" https://t.co/FJkVzj5A3i The article

Jun 13, 2023 · 19,137 followers View post →
rubic3n
@rubic3n · X

NMN Sirts https://t.co/uCinuaZpSA no flush

May 19, 2022 · 1 like · 1,777 followers View post →
Thomas Maxwell
@T_A_Maxwell · X

@ChrisDungeon @geravoin https://t.co/agNx5dM7H8

Jan 5, 2022 · 1 like · 154 followers View post →
Brett Weiss
@BrettJWeiss · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism https://t.co/2N3hWTC8t0

Nov 15, 2020 · 11 followers View post →
tiktak
@taisukun · X

ニコチンアミドモノヌクレオチド:NAD +代謝を標的とすることによる多様な疾患の治療のための有望な分子 https://t.co/QlNtl7jYrL

Oct 22, 2020 · 1 like · 304 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism https://t.co/ZMypNp69Mn #kahnchronicle

Sep 11, 2020 · 1 like · 32,258 followers View post →
Matthew McCombs
@mkmccombs · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism https://t.co/5m6CjCGL1F

Aug 27, 2020 · 37 followers View post →
Mike
@michaelscally · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism https://t.co/AkNPEJBlXs

May 31, 2020 · 894 followers View post →
UpToPhate
@UpToPhate · X

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism. https://t.co/Cppl2w6q2A

May 16, 2020 · 194 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism: NAD+, a co-enzyme involved in a great deal of biochemical reactions, has been found to be a network node of diverse… https://t.co/E637Y3NIAY #celldevbio

Apr 28, 2020 · 3,809 followers View post →