Synopsis of Social media discussions
The discussions reveal a balanced mix of technical curiosity and skepticism; for example, users debate the fidelity of the replication machinery and its components like RdRp, while others question the credibility of the publication based on its source. The tone varies from analytical to dismissive, reflecting differing levels of engagement and perceived relevance.
Agreement
Neither agree nor disagreeThe discussions reflect mixed opinions, with some questioning the reliability of claims about replication fidelity while others accept the structural insights.
Interest
Moderate level of interestMost comments show moderate interest, particularly in understanding the machinery involved in viral replication, though some posts dismiss or downplay the study's significance.
Engagement
Moderate level of engagementThere is some depth in engagement, as users discuss technical components like RdRp and proofreading enzymes, but overall participation remains relatively surface-level.
Impact
Moderate level of impactThe conversations suggest that the article influences some users' perceptions of viral replication, yet many remain skeptical or dismissive, indicating a moderate perceived impact.
Social Mentions
YouTube
2 Videos
8 Posts
News
4 Articles
1 Posts
Metrics
Video Views
29,306
Total Likes
957
Extended Reach
49,349
Social Features
15
Timeline: Posts about article
Top Social Media Posts
MotleySlate
@Kevin_McKernan @SynaptekLabs @NotJason666 @AnneliseBocquet @PinsolleT @PlanZip @dr_SDRK @TheJikky @denisrancourt @extemporea @BretWeinstein @ProfTimNoakes @delbigtree @FatEmperor @ArtemisiaBurge1 @pathocratie I question his low fidelity replication claim for this complex ~30k bp genome. Sure, there are errors, but isn't the replication machinery better than what he claims? RdRp nsp12, Helicase nsp13, RNA proofreader nsp14, and other nsp's are quite amazing.1/2
https://t.co/LN5wB022fu
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Cells MDPI
"A Structural View of #SARS-CoV-2 #RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping" from Romano et al.
#cellsmdpi #molecularbiology #cellbiology #COVID19 #RNAreplication #proteinstructure
Full text: https://t.co/aLBpLVYxNv https://t.co/kimZqREkLi
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Isatou Sarr
https://t.co/EnccwfB16r
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Bioinformatics Trends
RT @Cells_MDPI: "A Structural View of #SARS-CoV-2 #RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping" from Romano et…
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Maples the Syrup Frog
RT @MotleySlate: @Kevin_McKernan @SynaptekLabs @NotJason666 @AnneliseBocquet @PinsolleT @PlanZip @dr_SDRK @TheJikky @denisrancourt @extempo…
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Posts referencing the article
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RT @MotleySlate: @Kevin_McKernan @SynaptekLabs @NotJason666 @AnneliseBocquet @PinsolleT @PlanZip @dr_SDRK @TheJikky @denisrancourt @extempo…
view full postNovember 25, 2022
1
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MotleySlate
@MotleySlate (Twitter)@Kevin_McKernan @SynaptekLabs @NotJason666 @AnneliseBocquet @PinsolleT @PlanZip @dr_SDRK @TheJikky @denisrancourt @extemporea @BretWeinstein @ProfTimNoakes @delbigtree @FatEmperor @ArtemisiaBurge1 @pathocratie I question his low fidelity replication claim for this complex ~30k bp genome. Sure, there are errors, but isn't the replication machinery better than what he claims? RdRp nsp12, Helicase nsp13, RNA proofreader nsp14, and other nsp's are quite amazing.1/2 https://t.co/LN5wB022fu
view full postNovember 25, 2022
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Bioinformatics Trends
@BinfoTrends (Twitter)RT @Cells_MDPI: "A Structural View of #SARS-CoV-2 #RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping" from Romano et…
view full postJanuary 14, 2022
1
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Cells MDPI
@Cells_MDPI (Twitter)"A Structural View of #SARS-CoV-2 #RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping" from Romano et al. #cellsmdpi #molecularbiology #cellbiology #COVID19 #RNAreplication #proteinstructure Full text: https://t.co/aLBpLVYxNv https://t.co/kimZqREkLi
view full postJanuary 14, 2022
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Cristian Pérez
@CristianFPerezP (Twitter)@Autoformato @LexQDev @e_crisanto @Swanros Ya entiendo el porque cree en cualquier video que ve por internet. Si supiera leer se daría cuanta que es una publicación de la revista Cells. Esa es solo una copia en NCBI https://t.co/3da7kphJby Además, artículos con el código genetico existen miles.
view full postSeptember 24, 2021
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Isatou Sarr
@IsatouSarr4 (Twitter)https://t.co/EnccwfB16r
view full postApril 28, 2021
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LIgirl82
@longisland82 (Twitter)@kvwatchtay7 @viralvideovlogs Reference Romano, M., Ruggiero, A., Squeglia, F., Maga, G., & Berisio, R. (2020). A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping. Cells, 9(5), 1267. https://t.co/izhKQ5H4ok
view full postApril 14, 2021
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NFTdose
@PaperbirdsH (Twitter)New article: A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping. https://t.co/0AW8j48ZJK #coronavirus #COVID19 #2019ncov https://t.co/07IbAzsjs6
view full postMay 24, 2020
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Bickerton GR, Paolini GV, Besnard J, Muresan S, Hopkins AL. 1267. doi:10.3390/cells9051267 Quantifying the chemical beauty of drugs. Nat Chem. 2012;4: 13 ...
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http://dx.doi.org/10.3390/cells9051267 · http://dx.doi.org/10.1155/2021/6635925 · http://dx.doi.org/10.3390/medicina57030290 · http://dx.doi.org ...
view full postMay 27, 2024
Reddit
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Structure, lifecycle and replication machinery of SARS-CoV-2 | Book ...
17, https://doi.org/10.3390/cells9051267, under the terms of CC BY 4.0. (A) Genome of SARS-COV-2 showing individual ORFs. (B) Polyprotein 1ab ...
view full postMay 19, 2021
News
Abstract Synopsis
- The article focuses on how SARS-CoV-2 replicates its RNA inside infected cells, involving complex interactions between viral and host proteins for functions like RNA synthesis, proofreading, and capping.
- It highlights recent structural and functional data on key components of the viral replication machinery, mainly obtained through modeling and literature review, to better understand their roles and interactions.
- Cofactors such as Nsp8 and Nsp10 are emphasized as crucial players that activate and stabilize the replication complex, improving the virus's ability to efficiently replicate its RNA.]
Maples the Syrup Frog
@Maples46014332 (Twitter)