Sex-driven modifiers of Alzheimer risk: A multimodality brain imaging study.

Aneela Rahman, Eva Schelbaum, Katherine Hoffman, Ivan Diaz, Hollie Hristov, Randolph Andrews, Steven Jett, Hande Jackson, Andrea Lee, Harini Sarva, Silky Pahlajani, Dawn Matthews, Jonathan Dyke, Mony J de Leon, Richard S Isaacson

July 2020 Neurology

Synopsis of Social media discussions

The overall tone reflects strong agreement and high interest, as seen in comments about hormonal factors affecting Alzheimer’s and mentions of brain imaging techniques, indicating engagement with both the research's content and its future implications. Words like 'crucial', 'potential', and references to hormonal influences underscore the perceived significance and relevance of the study in understanding Alzheimer’s risk factors for women.

A
Agreement
 Moderate agreement

Most discussions acknowledge the importance of the study, with many recognizing hormonal factors as key modifiers in Alzheimer's risk, indicating general agreement with the publication's findings.

I
Interest
 High level of interest

The discussions demonstrate high interest by emphasizing the relevance of sex differences and hormonal influences, suggesting engagement beyond surface-level curiosity.

E
Engagement
 Moderate level of engagement

Comments referencing specific topics like menopause, hormonal therapy, and brain imaging imply a decent level of engagement, though mostly at a conceptual level rather than detailed critique.

I
Impact
 Moderate level of impact

Some posts highlight the potential implications for early intervention and awareness, suggesting recognition of the study's importance, but few delve into broader societal or clinical impact.

Social Mentions

YouTube

1 Videos

Facebook

2 Posts

Twitter

8 Posts

Blogs

3 Articles

News

30 Articles

Metrics

Video Views

1,767

Total Likes

168

Extended Reach

120,719

Social Features

44

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Hormonal Factors and Alzheimer’s Risk in Women Explained

Hormonal Factors and Alzheimer’s Risk in Women Explained

Middle-aged women exhibit higher amyloid buildup, lower brain metabolism, and reduced brain volume than men, linked to hormonal changes like menopause and hormone therapy, highlighting early intervention potential.

El Paciente Primero

June 30, 2020

1,767 views

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Abstract Synopsis

  • The study found that middle-aged women show higher levels of amyloid build-up, lower brain metabolism, and reduced brain volume compared to men, even when they are cognitively normal.
  • These sex differences in Alzheimer’s biomarkers are strongly linked to hormonal factors, especially menopause, hormone therapy, hysterectomy, and thyroid disease.
  • The results imply that early hormonal changes in women could be crucial for predicting and possibly preventing Alzheimer's disease, highlighting a potential window for intervention during midlife.