Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respiratory infection than placebo among vitamin D–deficient schoolchildren in Mongolia. @NEJM #vitaminDRCT https://t.co/138tpAatpY https://t.co/kbtpuVjclL
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease.
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Jul 2020 – Mar 2025Where it's discussed
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X / Twitter111 posts
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AI synopsis
What people are saying
Several discussions highlight that the study revealed no significant difference in tuberculosis infection rates among children taking vitamin D versus those on a placebo, with comments noting phrases like 'not surprising' and 'another failure' indicating a critical perspective. The tone and choice of words convey a mix of skepticism and disappointment, reflecting the broader concern about repeated studies showing similar negative results regarding vitamin D's effectiveness.
The majority of posts show some support for the article's findings, although a few express skepticism about the utility of vitamin D supplementation.
There is a notable level of curiosity about the implications of the study, as people seek to understand the results and their application.
While many discussions reference the study, offering cursory commentary, only a few engage in deeper analysis of methodologies or implications.
Most contributors recognize the potential significance of the findings, but the overall tone suggests disappointment, leading to a moderate perception of impact.
Abstract in brief
- This study examined the impact of vitamin D supplements on preventing tuberculosis infection among children over a 3-year period.
- 8,851 children were randomly assigned to receive either 14,000 IU of vitamin D or a placebo weekly, with follow-up outcomes including positivity rates for tuberculosis infections and changes in vitamin D levels.
- The results showed no significant difference in tuberculosis infection rates between the vitamin D and placebo groups, despite the vitamin D group having higher serum levels of the vitamin, indicating that vitamin D supplementation might not effectively lower tuberculosis infection risk.
Top posts
Most liked on X and BlueskyWhat will you do now @chadinabhan. I thought this was your last hope for vitamin D supplements, children in Mongolia... https://t.co/qGad7b1xDz
There were two goals to this study. 1st - see if Vitamin D supplementation could prevent latent TB infection (authors had prelim data supporting this). This was published a few months ago in @NEJM. Negative. https://t.co/LhgFn05Sc7 (4/N) https://t.co/Xbrpw1w7Fa
Kaynak: Ganmaa D, Uyanga B, Zhou X, et al. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. N Engl J Med. 2020 Jul 23;383(4):359-368. doi: 10.1056/NEJMoa1915176. PMID: 32706534; PMCID: PMC7476371. @NEJM
What is the definition of #insanity? doing the same thing over and over again, but expecting different results. How many negative #VitaminD supplement studies do we need before we stop doing any more #VitaminD suppl #RCTs? https://t.co/HcJiuwejba
Unfortunately vitamin D doesn't prevent TB infection (or treat it). New Paper out this week. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/5VGkBLG5iK #EndoTwitter Why is vitamin D low in sick people? Should it be corrected?
All mentions
Understanding Tuberculosis: Causes, Risks, and Treatments
Tuberculosis (TBC) is an infectious disease caused by Mycobacterium tuberculosis, affecting primarily the lungs but also other organs. This video explores its transmission, symptoms, diagnosis, and treatments, including…
Vitamin D Supplementation and its Role in COVID-19 Prevention
Prof. Adrian Martineau and Dr. Arne Soraas discuss the role of vitamin D supplementation in the general population for COVID-19 prevention based on their studies. They explore findings from the CORONAVIT and CLOC…
الدرن السل علاقته بنقص فيتامين د طالع الدراسه https://t.co/fmSVexsrTw
@AEffondrement @Tipuncho Les essais portent surtout chez les adultes de plus de 50 ans J'ai vu cet essai de grande taille chez les enfants de 6-13 ans https://t.co/VSDX01MuoG https://t.co/YbtDBX2d8d Il y en a sans doute d'autres, j'ai juste regardé les plus gd essais et dans les gros journaux https://t.co/Z2h7LApbfz
There were two goals to this study. 1st - see if Vitamin D supplementation could prevent latent TB infection (authors had prelim data supporting this). This was published a few months ago in @NEJM. Negative. https://t.co/LhgFn05Sc7 (4/N) https://t.co/Xbrpw1w7Fa
RT @TMC_online_: Kaynak: Ganmaa D, Uyanga B, Zhou X, et al. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. N E…
Kaynak: Ganmaa D, Uyanga B, Zhou X, et al. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. N Engl J Med. 2020 Jul 23;383(4):359-368. doi: 10.1056/NEJMoa1915176. PMID: 32706534; PMCID: PMC7476371. @NEJM
One study found #vitamind #supplements did not lower risk of #tuberculosis infection in children; while research on vitamin D and #COVID19 has been “mixed & sparse” (via @NEJM) https://t.co/4iuW4M7aYx https://t.co/C8n9zf12Kl #clinicalresearch #respirology @WHO https://t.co/NJczMNMqSJ
Aunque tampoco en deficientes parece que tenga efecto la administración de megadosis de vitamina D respecto a las infecciones respiratorias. https://t.co/G3Wg7hyjBN
RT @drdavidc: With ubiquitous COVID-19 research I nearly missed this hugely important piece of work which has been planned for some time: V…
RT @a_naranjoh: Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/6aY8mk9LIs
RT @drdavidc: With ubiquitous COVID-19 research I nearly missed this hugely important piece of work which has been planned for some time: V…
RT @drdavidc: With ubiquitous COVID-19 research I nearly missed this hugely important piece of work which has been planned for some time: V…
RT @lizWWyld: Amazing presentation of placebo controlled vitamin d study in Mongolia not showing any difference to TB infection or disease…
RT @lizWWyld: Amazing presentation of placebo controlled vitamin d study in Mongolia not showing any difference to TB infection or disease…
RT @lizWWyld: Amazing presentation of placebo controlled vitamin d study in Mongolia not showing any difference to TB infection or disease…
Amazing presentation of placebo controlled vitamin d study in Mongolia not showing any difference to TB infection or disease amongst other markers by Adrian Martineau @bpaiig @RCPCHtweets https://t.co/j234Ed42Kd
La suplementación con vitamina D no redujo riesgo de infección por #tuberculosis, enfermedad de tuberculosis o IRA vs placebo entre los escolares con deficiencia de vitamina D en Mongolia https://t.co/UqcqKlRpbh
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/sC1sIyfy5w
RT @neurologo: En resumen, los que recetaban sol y aire de montaña para la TB hace 150 años estaban equivocados; como lo suponíamos. Vita…
En resumen, los que recetaban sol y aire de montaña para la TB hace 150 años estaban equivocados; como lo suponíamos. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/plcm9CUKtF
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease - Dr. John Sangwon Lees P https://t.co/tjVPzX77zP
Studie: Vitamin D schützt nicht vor Tuberkulose & anderen Infektionskrankheiten #Medizin #News #Medizinnews #Tuberkulose #VitaminD Zur Studie: https://t.co/cbLqT6aMn8 https://t.co/YlZ3gNAs8c
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. https://t.co/RZRPuXq3I3
【RCT】QFT検査陰性の小児へのビタミンD3の投与は、プラセボと比較して、3年間のQFT陽性率を減少させなかった[3.6% (147 of 4074 children) vs. 3.3% (134 of 4043), adjusted risk ratio 1.10 (95%CI 0.87 - 1.38; P = 0.42)]。 #ペ読 https://t.co/HkraxIx61Z
RT @KarminnaE: Studies have shown vit D helps improve response to mycobacterium
RT @2minmed: #VisualAbstract: Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease https://t.co/ggF3iaE5QE #StudyGrap…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
#VisualAbstract: Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease https://t.co/ggF3iaE5QE #StudyGraphics #supplementation https://t.co/GGlPG7GrjC
Studies have shown vit D helps improve response to mycobacterium
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
【結核】 週1回3年間のビタミン D の摂取は、プラセボと比較して、結核感染や結核症、急性呼吸器感染症のリスクを低下させなかった。 モンゴルの学齢児の研究。 PMID:32706534 https://t.co/7vGLdNVrri
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. https://t.co/WotGzR3anJ
RT @YaleSPH: @YaleSPH faculty Xin Zhou & Donna Spiegelman, along with colleagues from several other universities, published findings in @N…
RT @YaleSPH: @YaleSPH faculty Xin Zhou & Donna Spiegelman, along with colleagues from several other universities, published findings in @N…
@YaleSPH faculty Xin Zhou & Donna Spiegelman, along with colleagues from several other universities, published findings in @NEJM demonstrating that vitamin D supplementation does not lower children’s risk of #TB infection - contradicting previous studies. https://t.co/s5zgOaZuVJ
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease. https://t.co/xDyJJjcs11
#TB y vitamina D. Suplemento de vitamina D no resultó en menor riesgo de tuberculosis o infección respiratoria aguda que placebo entre los escolares con deficiencia de vitamina D en Mongolia/2 @SOVETORAX @zheniaff @TheUnion_TBLH https://t.co/q51wsBi5Si
RT @DrHiggsboson: @zegirish @theguardianp53 @poochandi007 https://t.co/h0am4bXg97
@zegirish @theguardianp53 @poochandi007 https://t.co/h0am4bXg97
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM (Rated: Positive Bias) https://t.co/TUIUR4ILEk
RT @buzzingscience: #science #STEM Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/vQfbJyaHG…
RT @isidoro_cano: Este RCT muestra que suplementar con 14000UI/semana de Vit D a niños (96,5% <20ng/ml) NO tiene beneficio en prevención in…
Este RCT muestra que suplementar con 14000UI/semana de Vit D a niños (96,5% <20ng/ml) NO tiene beneficio en prevención infecciones respiratorias o Tbc, aunque se alcance 31ng/ml vs 10mg/ml en grupo Pbo al final del estudio https://t.co/KTbMfZvCWO https://t.co/eUFKngNSIE
RT @fatlester: Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease https://t.co/cDicUGPRiA
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/ZGaRfiEFJ2
#NEJM (RCT)Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respiratory infection than placebo among vitamin D–deficient schoolchildren in Mongolia https://t.co/Zr0ZTnaYuF
RT @dminderapp: https://t.co/3zlimvBMTW
(NEJM) Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease https://t.co/gJiXBoHHbV
RT @dminderapp: https://t.co/3zlimvBMTW
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
https://t.co/3zlimvBMTW
Es que creo ya tenemos bastante claro. No va de suplementos, va de comer sano, pero bueno, es un estudio bien hecho. Aunque yo les hubiera dado dieta sana de verdad a ver qué tal... https://t.co/XqCOToc5ki
RT @Links_Medicus: [Abstract Only] Randomized trial: Vitamin D does not prevent tuberculosis or acute respiratory infections in children –…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
結核感染および結核症予防のためのビタミンDサプリメント "ビタミンDが不足している結核菌検査陰性の小児を,ビタミンD3を週1回投与する群とプラセボを投与する群に無作為に割り付けた.3年の時点で結核菌検査陽性の小児の割合に群間で差は認められなかった"(NEJM) https://t.co/jTzjLXdOtt
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
“Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respiratory infection than placebo among vitamin D–deficient schoolchildren in Mongolia” https://t.co/FuqdsVqwsf
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
https://t.co/xper9ZFSTG https://t.co/aZp6rJ4o7w
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
[Abstract Only] Randomized trial: Vitamin D does not prevent tuberculosis or acute respiratory infections in children – via @NEJM https://t.co/BzCpfnFfCi
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @ABsteward: Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respirato…
RT @thierrysouccar: Pas de protection des suppléments de vitamine D (14000 UI/semaine pendant 3 ans) contre la tuberculose. Étude contrôlée…
Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respiratory infection than placebo among vitamin D–deficient schoolchildren in Mongolia. @NEJM #vitaminDRCT https://t.co/138tpAatpY https://t.co/kbtpuVjclL
RT @thierrysouccar: Pas de protection des suppléments de vitamine D (14000 UI/semaine pendant 3 ans) contre la tuberculose. Étude contrôlée…
RT @donsin4: What is the definition of #insanity? doing the same thing over and over again, but expecting different results. How many negat…
What will you do now @chadinabhan. I thought this was your last hope for vitamin D supplements, children in Mongolia... https://t.co/qGad7b1xDz
RT @vtangpricha: Unfortunately vitamin D doesn't prevent TB infection (or treat it). New Paper out this week. Vitamin D Supplements for Pre…
Unfortunately vitamin D doesn't prevent TB infection (or treat it). New Paper out this week. Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/5VGkBLG5iK #EndoTwitter Why is vitamin D low in sick people? Should it be corrected?
RT @thierrysouccar: Pas de protection des suppléments de vitamine D (14000 UI/semaine pendant 3 ans) contre la tuberculose. Étude contrôlée…
RT @thierrysouccar: Pas de protection des suppléments de vitamine D (14000 UI/semaine pendant 3 ans) contre la tuberculose. Étude contrôlée…
Pas de protection des suppléments de vitamine D (14000 UI/semaine pendant 3 ans) contre la tuberculose. Étude contrôlée sur près de 9000 enfants. ➡️ N’attendons pas trop de la supplémentation en vitamine D dans les maladies infectieuses.https://t.co/3dxe5Lf3bg
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @donsin4: What is the definition of #insanity? doing the same thing over and over again, but expecting different results. How many negat…
RT @drjohnmorley: Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/epXOpNkYu9 Another failur…
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease | NEJM https://t.co/epXOpNkYu9 Another failure of Vitamin D.Not surprising
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @DanielJDrucker: The Emperor of Associations Flunks Another RCT " #VitaminD supplementation did not result in a lower risk of tuberculo…
RT @drdavidc: With ubiquitous COVID-19 research I nearly missed this hugely important piece of work which has been planned for some time: V…
Interesting study in >8800 children. Vit D did not prevent TB. Kids supplemented oral 14,000iu/week. End 3yr study 3.6% got TB in vit D group c/o 3.3% in the placebo. Mean 25(OH)D level end trial 31ng/mL vit D group & 10.7ng/mL placebo i.e both deficient https://t.co/FsFbrtZH2U
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @boback: Hey, more Vitamin D obs research led to an RCT that found nothing. Great job folks! https://t.co/ob6ftWxIcq @NEJM
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @boback: Hey, more Vitamin D obs research led to an RCT that found nothing. Great job folks! https://t.co/ob6ftWxIcq @NEJM
RT @drdavidc: With ubiquitous COVID-19 research I nearly missed this hugely important piece of work which has been planned for some time: V…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
La suplementación de vitamina D no resultaría en menor riesgo de infección, enfermedad o infección respiratoria aguda por tuberculosis en escolares con deficiencia de vitamina D https://t.co/1735JWDIqS
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @dr_michaelmarks: Vitamin D doesn't prevent TB @NEJM https://t.co/wzF3sTQRyP Vitamin D now failed trials ICU Cancer heart disease diabe…
RT @donsin4: What is the definition of #insanity? doing the same thing over and over again, but expecting different results. How many negat…
What is the definition of #insanity? doing the same thing over and over again, but expecting different results. How many negative #VitaminD supplement studies do we need before we stop doing any more #VitaminD suppl #RCTs? https://t.co/HcJiuwejba
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease https://t.co/cDicUGPRiA
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