An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression.

Karmel W Choi, Murray B Stein, Kristen M Nishimi, Tian Ge, Jonathan R I Coleman, Chia-Yen Chen, Andrew Ratanatharathorn, Amanda B Zheutlin, Erin C Dunn, , , Gerome Breen, Karestan C Koenen, Jordan W Smoller

October 2020

Synopsis of Social media discussions

Numerous discussions emphasized the role of social connections as a protective factor against depression, with phrases like 'social connection is the strongest protective factor' and 'phone a friend, or arrange to meet for coffee,' showcasing urgency and practical advice. The tone is predominantly affirmative, with users celebrating the article's findings and contributing their experiences, suggesting a community deeply invested in the topic.

A
Agreement
 Strong agreement

Many posts express strong support for the conclusions regarding modifiable factors for preventing depression.

I
Interest
 High level of interest

The discussion reflects high curiosity, as participants cite specific findings and potential applications.

E
Engagement
 High engagement

Contributors demonstrate deep engagement by referencing methods like Mendelian randomization and discussing various lifestyle factors related to depression.

I
Impact
 High level of impact

The community perceives the publication's findings as having significant implications for mental health strategies.

Social Mentions

YouTube

2 Videos

Facebook

3 Posts

Twitter

118 Posts

Blogs

16 Articles

News

206 Articles

Reddit

3 Posts

Metrics

Video Views

405

Total Likes

346

Extended Reach

874,069

Social Features

348

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Exploring Modifiable Factors in Depression Risk and Prevention

Exploring Modifiable Factors in Depression Risk and Prevention

This conversation features Dr. Joni Coleman discussing depression and how genetics, environment, and trauma influence mental health. The study emphasizes modifiable factors like social support and television viewing as significant in preventing depression. Learn more about the Medical Research Foundation's mission.

Medical Research Foundation

April 11, 2025

339 views

Identifying Modifiable Factors for Depression Prevention

Identifying Modifiable Factors for Depression Prevention

This study used data from over 100,000 UK Biobank participants to explore modifiable factors related to depression prevention. While many factors were linked to depression, only a few, like social support and television watching, showed strong causal evidence for effective prevention strategies.

rakesh kota

June 20, 2021

66 views

  • Brasileiro Indignado
    @lv_psi (Twitter)

    RT @PGCgenetics: While many risk factors for #depression cannot be readily avoided, modifiable factors offer promise for #prevention. Men…
    view full post

    May 29, 2024

    1

  • PGC Consortium
    @PGCgenetics (Twitter)

    While many risk factors for #depression cannot be readily avoided, modifiable factors offer promise for #prevention. Mendelian randomization has been used to validate a wide range of risk and protective factors for depression risk. https://t.co/bB0OJ9yhnK
    view full post

    May 28, 2024

    5

    1

  • lg
    @Aleekeleke (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    January 1, 2024

    14

  • Miguel Sandoval
    @miguel_sand13 (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • Lápiz táctico
    @chicoopopulaar (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • R Giovanni Diaz-Zavala
    @DrGiovanniD (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • La Guerra se acerca
    @tryo1 (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • Bárbara
    @BarbaraVieiraF (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • luis alberto lopez
    @luislopezneyra (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • Erick CC
    @Erick_lxvi (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • Percy Mayta-Tristán
    @MaytaTristan (Twitter)

    RT @IlindelatorreMD: Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidade…
    view full post

    December 31, 2023

    14

  • Dr. Ilin Gilberto de la Torre M.
    @IlindelatorreMD (Twitter)

    Las personas que tienen amigos y confidentes cercanos están más satisfechas con sus vidas y tienen menos probabilidades de sufrir depresión https://t.co/Ksu8QH0I0T https://t.co/vURTybeOUi
    view full post

    December 31, 2023

    38

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  • Katie Lockwood, MD, MEd
    @drkatielockwood (Twitter)

    Social connection is the most protective factor against depression. Choose your colleagues & geography carefully. Be with your people. https://t.co/qlMmoruo14
    view full post

    March 9, 2023

    6

  • Sualeha Irshad
    @sualehairshad (Twitter)

    ... validating the impact of trusted social connections as causally protective for depression" https://t.co/L9X4JEDvRJ
    view full post

    October 11, 2022

    1

  • Dr Michael Mol
    @DrMichaelMol (Twitter)

    Phone a friend, or arrange to meet for coffee. This time is never wasted. Even if you have a genetic risk of developing #depression, the benefit of having a strong social network and good social connections can mitigate this risk https://t.co/aII5D1hYq1
    view full post

    August 24, 2022

    2

  • Dr Michael Mol
    @DrMichaelMol (Twitter)

    Improving #social connection is one of the strongest factors that protects against #depression, while reducing sedentary activities such as TV watching and daytime napping could also help lower your risk https://t.co/aII5D1hYq1
    view full post

    August 24, 2022

    2

  • kamokita
    @kamokita1 (Twitter)

    #今日の論文読み https://t.co/pNm2hd41Zt RQ：うつ病の予後因子の探索 データソース：UK BioBank Size：100000 解析手法：Mendelian Randomization Analyses アウトカム：うつ病リスク 特徴量：社会人口学的要因 /身体的健康要因 結論：友人家族を信頼と頻繁な交流が、うつ病のリスクを下げる
    view full post

    August 9, 2022

  • Dr. Ceyhun Nuri
    @drceyhunnuri (Twitter)

    ne kadar çok televizyon izlerseniz, zihinsel sağlığınızın o kadar kötü olur, diyor bu çalışma https://t.co/rY4LhQOOvK
    view full post

    July 23, 2022

  • Lorenza Dall'Aglio
    @L_DallAglio (Twitter)

    This work will follow up on @karmelchoi’s project on modifiable causal factors for depression incidence in adults from the UK Biobank https://t.co/queYWftWSX by focusing on earlier ages and adopting longitudinal methods in @GenerationR_010 and ABCD
    view full post

    July 13, 2022

    2

  • Petri Böckerman
    @pbockerman (Twitter)

    @lauri_paavola Ks. https://t.co/rI7xJ1O8BK
    view full post

    January 30, 2022

  • kirk lee
    @gingerdays (Twitter)

    RT @RCarhartHarris: A little late to the party but this looks important: An Exposure-Wide and Mendelian Randomization Approach to Identifyi…
    view full post

    October 7, 2021

    4

  • REMAP Therapeutics
    @REMAPTherapy (Twitter)

    RT @RCarhartHarris: A little late to the party but this looks important: An Exposure-Wide and Mendelian Randomization Approach to Identifyi…
    view full post

    October 6, 2021

    4

  • Matthew Johnson
    @anandabits (Twitter)

    RT @RCarhartHarris: A little late to the party but this looks important: An Exposure-Wide and Mendelian Randomization Approach to Identifyi…
    view full post

    October 4, 2021

    4

  • Cecily Whiteley
    @cecilymwhiteley (Twitter)

    RT @RCarhartHarris: A little late to the party but this looks important: An Exposure-Wide and Mendelian Randomization Approach to Identifyi…
    view full post

    October 4, 2021

    4

  • Robin Carhart-Harris
    @RCarhartHarris (Twitter)

    A little late to the party but this looks important: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/no5AHoiKCf
    view full post

    October 4, 2021

    19

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  • Dr. Lydia Roos
    @LydiaGRoos (Twitter)

    RT @sjdimitroff: Great article that analyzed over 100 modifiable factors related to depression. Once again social contact was found to be p…
    view full post

    August 16, 2021

    1

  • Stephanie Dimitroff
    @sjdimitroff (Twitter)

    Great article that analyzed over 100 modifiable factors related to depression. Once again social contact was found to be protective. Bonus finding -> cheese intake is related to lower odds of depression!
    view full post

    August 16, 2021

    7

    1

  • Sports Coach Radio
    @sportscoachtalk (Twitter)

    Social connection is the strongest protective factor against depression, according to recently published research. The study identified more than 100 possible changes that people could make to their lives to reduce the risk of depression. https://t.co/2Vsnpf5CV1
    view full post

    August 9, 2021

  • Giovanni Giffoni
    @ggffgiffoni (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    June 27, 2021

    11

  • BetaGov
    @BetaInnovation (Twitter)

    Vitamin D & depression: new research disputes previous conclusions, now suggests no benefits; https://t.co/FZUERe7ZDO, but another study shows that strengthening social connections may be the most effective way to prevent depression https://t.co/U7NtIFZXcB
    view full post

    February 22, 2021

  • NYU Urban Epidemiology Lab
    @nyu_uel (Twitter)

    An exposure-wide study recently published in @AMJPublicHealth identified social factors such as confiding in others and visiting friends & family as the strongest protective factors for depressive symptoms among British adults: https://t.co/KVpopHCVRj.
    view full post

    November 3, 2020

  • د. محمد الشمري
    @MohdNeuro (Twitter)

    RT @MohdNeuro: دراسة حديثة قامت بها مجموعة بحثية من MGH التابعة لهارفرد ببوسطن ونشرت في المجلة الامريكية للطب النفسي؛ عن العوامل التي بالام…
    view full post

    October 31, 2020

    1

  • Darlynn Rojo-Wissar, PhD, MPH
    @DrRedWizard (Twitter)

    RT @JamieLarsH: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression ht…
    view full post

    September 29, 2020

    4

  • Carlos E Alvarez
    @CarlosEAlvare17 (Twitter)

    RT @JamieLarsH: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression ht…
    view full post

    September 29, 2020

    4

  • CLaE
    @leafs_s (Twitter)

    RT @JamieLarsH: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression ht…
    view full post

    September 29, 2020

    4

  • Luke Norman
    @Luke_J_Norman (Twitter)

    RT @JamieLarsH: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression ht…
    view full post

    September 29, 2020

    4

  • Jamie Hanson (@jamielarsh.bsky.social)
    @JamieLarsH (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression https://t.co/ecSHrZMtAF https://t.co/BkT78dhBrl
    view full post

    September 29, 2020

    11

    4

  • Ciência Pra Você - UFMG
    @cienciapravoce (Twitter)

    Fonte: https://t.co/JcEGDjPGsu https://t.co/K6Io9xciXv https://t.co/wBgVqJBwi0
    view full post

    September 10, 2020

  • 塩川宏郷
    @ddtsubucafe (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depre… https://t.co/x869wZ65DL
    view full post

    September 2, 2020

  • Joo-Yeon Lee
    @jylee521 (Twitter)

    RT @Mendelian_lit: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression…
    view full post

    August 28, 2020

    2

  • Dr Michael Mol
    @DrMichaelMol (Twitter)

    Phone a friend, or arrange to meet for coffee. This time is never wasted. Even if you have a genetic risk of developing #depression, the benefit of having a strong social network and good social connections can mitigate this risk https://t.co/aII5D1hqAt
    view full post

    August 27, 2020

    7

  • Dr Michael Mol
    @DrMichaelMol (Twitter)

    Improving #social connection is one of the strongest factors that protects against #depression, while reducing sedentary activities such as watching TV and daytime napping could also help lower your risk https://t.co/aII5D1hqAt
    view full post

    August 26, 2020

    4

  • Eduard García Pedregal
    @eduardgarpe (Twitter)

    RT @Sanalala5: Análisis de múltiples factores modificables relacionados con la prevención de la depresión: un mayor apoyo social, menos hor…
    view full post

    August 26, 2020

    1

  • Sanalalá
    @Sanalala5 (Twitter)

    Análisis de múltiples factores modificables relacionados con la prevención de la depresión: un mayor apoyo social, menos horas de TV y no echarse la siesta, entre los más destacables https://t.co/iOWsLt9vHF #Depresion
    view full post

    August 25, 2020

    1

    1

  • Shahd Douglas
    @shahd_douglas (Twitter)

    RT @RimadsQA: A study suggests confiding in others is one of the best ways to stave off depression, while daytime napping and spending lots…
    view full post

    August 22, 2020

    2

  • Swapnendu Sanyal
    @swapnendusanyal (Twitter)

    RT @RimadsQA: A study suggests confiding in others is one of the best ways to stave off depression, while daytime napping and spending lots…
    view full post

    August 22, 2020

    2

  • Oden
    @Gjallarhornet (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of #Depression https://t.co/mUwclkAKYE
    view full post

    August 22, 2020

    1

  • Rimads App
    @Rimadsapp (Twitter)

    A study suggests confiding in others is one of the best ways to stave off depression, while daytime napping and spending lots of time watching television appear to increase the risk of developing the condition. https://t.co/PIBFJ1gHjH #mentalhealth #rimads #techstartup #Health
    view full post

    August 22, 2020

    2

    2

  • Pradip Kumar Ganguly
    @Adipkr (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/2Aby2p6e3I
    view full post

    August 20, 2020

    1

  • Austen Riggs Center
    @AustenRiggs (Twitter)

    Dr. @EricPlakunMD responds to the American Journal of Psychiatry article: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of #Depression https://t.co/qixvVnW5Ob https://t.co/gxRLBfNEx1
    view full post

    August 20, 2020

  • Henry Kimmel, Psy.D.
    @geropsych (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/nuf9852vfj
    view full post

    August 20, 2020

  • Oliver Shannon
    @Oli_Shannon (Twitter)

    RT @hobbs_PA: New study from @harvardmed showing that social connection is the strongest protective factor for #depression ping @SimonKingh…
    view full post

    August 20, 2020

    1

  • Mollie Wilson
    @MrsWilsonOJHS (Twitter)

    TL;DR study show confiding in others a major protective factor in reducing depression. Social support is huge for mental health. https://t.co/LE9PAOUzz7
    view full post

    August 19, 2020

  • Steph WeIIs, Ph.D.
    @sw4618 (Twitter)

    RT @JackieBullis:
    view full post

    August 19, 2020

    1

  • Dr Matthew Hobbs
    @hobbs_PA (Twitter)

    New study from @harvardmed showing that social connection is the strongest protective factor for #depression ping @SimonKingham @CampbellMH https://t.co/ec8yPIkZYw Important given current #COVID19 situation with the social distancing and separation from friends and family https://t.co/kX5Bg0xcKc
    view full post

    August 19, 2020

    8

    1

  • sakanoue no fusigi
    @seeker98747 (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Jackie Bullis, PhD
    @JackieBullis (Twitter)


    view full post

    August 19, 2020

    10

    1

  • cft
    @ctrucolo (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Ed Valesi
    @Ed_valesi (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Yuliy
    @Yuliy_sirius_ (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11


  • @balkraix (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Zorus
    @ZorusBP (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Marcelo Simas
    @marcelosimas3 (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Suani Pilau
    @suani_pilau (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Arthur
    @Aether_A01 (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Lucca Horta
    @HortaLucca (Twitter)

    RT @EliVieiraJr: Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a…
    view full post

    August 19, 2020

    11

  • Eli Vieira
    @EliVieiraJr (Twitter)

    Estudo geneticamente informado (UK) sobre o risco de depressão: - Associado ao que ajuda: desabafar com alguém. Visitar a família. Exercícios. - Associado ao que atrapalha: muito tempo vendo TV. Cochilar durante o dia. Tomar multivitamínicos (?). https://t.co/Jy9UfAbOAx https://t.co/mtpfmCrRHC
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    August 19, 2020

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  • Reinis Lazda
    @ReinisLazda (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Steve Stewart-Williams
    @SteveStuWill (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • The Truth is Real
    @RealAdamB1 (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Strawman
    @StrawmanMeBros (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Strawman
    @StrawmanMeBro (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 19, 2020

    11

  • Jonathan Kolikant
    @JonKolikant (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 18, 2020

    11

  • Altamiro Bottino
    @BottinoAltamiro (Twitter)

    Study identifies social connection as the strongest protective factor for depression https://t.co/dL6EQOeNfe https://t.co/MSZqGKd89r https://t.co/y7pKAVHtE5
    view full post

    August 18, 2020

  • Harvard2TheBigHouse
    @Harvard2H (Twitter)

    RT @Scientific_Bird: To prevent depression, it may help confiding in others. An example of a study using a genetically informed research d…
    view full post

    August 18, 2020

    11

  • Inquisitive Bird
    @Scientific_Bird (Twitter)

    To prevent depression, it may help confiding in others. An example of a study using a genetically informed research design to investigate the possible importance of environmental variables. Source: https://t.co/YFLaCtw9kf https://t.co/dIG0tqu2Ag
    view full post

    August 18, 2020

    54

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  • كُنت … توته..
    @AB_ah505 (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 18, 2020

    16

  • JD Richardson
    @JDRichardsonMD (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/gnRuKnimvM
    view full post

    August 18, 2020

  • Center for Mental Health Research & Initiative
    @Cemhri (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression https://t.co/UcwU1c6fJl
    view full post

    August 18, 2020

  • SEPSM
    @SEPsiq (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/voRukUagx2
    view full post

    August 17, 2020

    1

  • د. محمد الشمري
    @MohdNeuro (Twitter)

    دراسة حديثة قامت بها مجموعة بحثية من MGH التابعة لهارفرد ببوسطن ونشرت في المجلة الامريكية للطب النفسي؛ عن العوامل التي بالامكان تغييرها لمنع حدوث الاكتئاب، درسوا أكثر من 100 عامل على مايقارب ال100,000 مشارك.. [1/2] https://t.co/4u6TH7lk6W https://t.co/NRnRLjCXLe
    view full post

    August 17, 2020

    4

    1

  • Jordan Smoller
    @jorsmo (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 17, 2020

    6

  • Reiner 
    @erlesen (Twitter)

    RT @erlesen: Study identifies social connection as the strongest protective factor for depression https://t.co/6u0D3x89N7 An Exposure-Wide…
    view full post

    August 17, 2020

    2

  • Psiquiatria Infantil
    @PsiqInfantil (Twitter)

    RT @APAPubJournals: Using a Mendelian randomization strategy on data from 100,000 UK Biobank participants, the authors identify factors rel…
    view full post

    August 17, 2020

    1

  • Journals of The American Psychiatric Association
    @APAPubJournals (Twitter)

    Using a Mendelian randomization strategy on data from 100,000 UK Biobank participants, the authors identify factors related to sleep, diet, and exercise as potentially modifiable risk factors in depression prevention efforts. Learn More: https://t.co/mTUbUVGzYE https://t.co/JzeOlSKahE
    view full post

    August 17, 2020

    3

    1

  • Michael Birkjær
    @MichaelBirkjaer (Twitter)

    RT @V_Bainton: Active social connection is the strongest protective factor for depression @hart_hansen @MichaelBirkjaer @MeikWiking #health…
    view full post

    August 17, 2020

    1

  • Vernon Bainton
    @V_Bainton (Twitter)

    Active social connection is the strongest protective factor for depression @hart_hansen @MichaelBirkjaer @MeikWiking #healthandhappiness #isolation #depression and the study is published here https://t.co/jHRALvDMjG https://t.co/hiwbaN6RIT
    view full post

    August 17, 2020

    1

    1

  • The Aegean Society
    @aegeansociety (Twitter)

    Yeni bir araştırmaya göre, aktif sosyal bağlantı depresyon için en güçlü koruyucu faktördür. Ek olarak, TV izlemek veya kestirmek gibi hareketsiz aktiviteleri azaltmak da depresyon riskini azaltmaya yardımcı olabilir. https://t.co/Me3r5WRI7t
    view full post

    August 17, 2020

    5

  • いっぽ
    @hikaritomizu (Twitter)

    RT @Luke_629: https://t.co/fvvqeHM5UL ABCDという小児思春期ビッグデータを用いて、 うつ病の予防を目的に、 遺伝子の指標PRSやトラウマで対象を絞り、 曝露因子と新規発症うつ病との関係を 因果関係までメンデリアンランダマイゼーションで検…
    view full post

    August 16, 2020

    5

  • afcp
    @afcp_01 (Twitter)

    RT @Luke_629: https://t.co/fvvqeHM5UL ABCDという小児思春期ビッグデータを用いて、 うつ病の予防を目的に、 遺伝子の指標PRSやトラウマで対象を絞り、 曝露因子と新規発症うつ病との関係を 因果関係までメンデリアンランダマイゼーションで検…
    view full post

    August 16, 2020

    5

  • Luke Nakaji/中島 振一郎@バルサと島巡りと猫と精神医療
    @Luke_629 (Twitter)

    RT @Luke_629: https://t.co/fvvqeHM5UL ABCDという小児思春期ビッグデータを用いて、 うつ病の予防を目的に、 遺伝子の指標PRSやトラウマで対象を絞り、 曝露因子と新規発症うつ病との関係を 因果関係までメンデリアンランダマイゼーションで検…
    view full post

    August 16, 2020

    5

  • نبض_العدالة
    @Justis_2018 (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 16, 2020

    16

  • BioMedWorks LLC @ biomedworks.substack.com
    @L_Kragie_MD (Twitter)

    RT @erlesen: Study identifies social connection as the strongest protective factor for depression https://t.co/6u0D3x89N7 An Exposure-Wide…
    view full post

    August 15, 2020

    2

  • Reiner 
    @erlesen (Twitter)

    Study identifies social connection as the strongest protective factor for depression https://t.co/6u0D3x89N7 An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression https://t.co/Fmlho0i9Yc
    view full post

    August 15, 2020

    2

    2

  • T.Iiduka Welfare
    @ti_Welfare (Twitter)

    RT @Luke_629: https://t.co/fvvqeHM5UL ABCDという小児思春期ビッグデータを用いて、 うつ病の予防を目的に、 遺伝子の指標PRSやトラウマで対象を絞り、 曝露因子と新規発症うつ病との関係を 因果関係までメンデリアンランダマイゼーションで検…
    view full post

    August 15, 2020

    5

  • Luke Nakaji/中島 振一郎@バルサと島巡りと猫と精神医療
    @Luke_629 (Twitter)

    https://t.co/fvvqeHM5UL ABCDという小児思春期ビッグデータを用いて、 うつ病の予防を目的に、 遺伝子の指標PRSやトラウマで対象を絞り、 曝露因子と新規発症うつ病との関係を 因果関係までメンデリアンランダマイゼーションで検討した研究です。 手法も含めて勉強になります。
    view full post

    August 15, 2020

    23

    5

  • د. دانيا الجارودي
    @Daljaroudi (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • فهد بن علي بن نوح
    @Fahadbinnouh (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • Science news
    @UpdateonScience (Twitter)

    https://t.co/jBdDWQY1z3 Study identifies social connection as the strongest protective factor for depression #sciencenews https://t.co/u7krs2g3p7
    view full post

    August 15, 2020

  • A.Aziz Hafiz عبدالعزيز حافظ
    @azizhafiz80s (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • Fredric Azariah
    @FredricAzariah (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | American Journal of Psychiatry https://t.co/QTJyoJMNbZ
    view full post

    August 15, 2020

  • Prof Miranda Wolpert
    @mirandarwolpert (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 15, 2020

    6

  • Dɾ Sααԃ Aʅ Bυɠαɱι. FSCAI د. سعد البقمي
    @bogamisa (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • Danielle DeVille, PhD
    @dcdville (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 15, 2020

    6

  • Magdalena Sevilla MSc PhD
    @magdasevilla22 (Twitter)

    RT @Mendelian_lit: An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression…
    view full post

    August 15, 2020

    2

  • Abdulwahab Al-Sarhan
    @iWhoob (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • بنت حرب
    @f8gjz0U9tsXA1om (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • ..
    @4nV1FQUMuYMQjWS (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • ثامر بن نواف بن يوسف السعدون
    @Thamerzo6 (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • عبدالعزيز النخيلان
    @alnokhilan (Twitter)

    RT @DRKAMALAYOUB: دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوام…
    view full post

    August 15, 2020

    16

  • الدكتور كمال أيوب
    @DRKAMALAYOUB (Twitter)

    دراسة على ما يزيد من ١٠٠ألف شخص وجدت أن أكثر العوامل حماية من الاكتئاب هو التواصل والترابط الاسري والاجتماعي وأكثر العوامل إرتباطاً بالاكتئاب هو كثرة مشاهدة التلفزيون ،القيلولة اثناء النهار والاستخدام المستمر للڤيتامينات . https://t.co/jYmdxiuC76
    view full post

    August 15, 2020

    37

    16

  • MR_lit
    @Mendelian_lit (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression. https://t.co/BDo5FEEqH6
    view full post

    August 15, 2020

    2

  • Madalina Jäger (PhD)
    @MadalinaJager (Twitter)

    Study identifies social connection as the strongest protective factor for depression Karmel W. Choi et al, An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression, American Journal of Psychiatry (2020).
    view full post

    August 15, 2020

    3

  • AT
    @a_tomyshev (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 15, 2020

    6

  • Associate Professor Amy Finlay-Jones
    @amyfinlayjones (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 14, 2020

    6

  • UCLA Stress Lab
    @UCLAStressLab (Twitter)

    RT @mpwpaulus: This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social con…
    view full post

    August 14, 2020

    6

  • Trends in Psychiatry
    @TrendsPsych (Twitter)

    An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression #depression #mentalhealth https://t.co/avUxl3krjp
    view full post

    August 14, 2020

  • Martin Paulus
    @mpwpaulus (Twitter)

    This is a very important paper highlighting several modifiable risk factors for depression - emphasis on "trusted social connections" https://t.co/S66yRGsdpU
    view full post

    August 14, 2020

    18

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Abstract Synopsis

  • This study used data from over 100,000 UK Biobank participants to explore a variety of modifiable factors related to the prevention of depression.
  • Researchers identified 106 factors across lifestyle, social, and environmental domains and focused on individuals at risk for depression through genetic and life event assessments.
  • They found that while many factors were linked to depression, only a few, like social support and television watching, had strong causal evidence, highlighting the need for further validation in prevention strategies.