Virulence genes and previously unexplored gene clusters in four commensal spp. isolated from the human throat expand the neisserial gene repertoire.

Alan Calder, Chukwuma Jude Menkiti, Aylin Çağdaş, Jefferson Lisboa Santos, Ricarda Streich, Alice Wong, Amir H Avini, Ebrima Bojang, Karththeepan Yogamanoharan, Nivetha Sivanesan, Besma Ali, Mariam Ashrafi, Abdirizak Issa, Tajinder Kaur, Aisha Latif

September 2020

Synopsis of Social media discussions

The overall tone reflects a recognition of the research’s importance, with phrases like 'expand the gene repertoire' and 'virulence genes' indicating curiosity about bacterial functions. Posts mention specific gene systems, such as Type VI Secretion, which demonstrate a deeper engagement with the subject matter, and the tone varies from neutral acknowledgment to cautious optimism about the implications of discovering virulence factors in normally harmless bacteria.

A
Agreement
 Moderate agreement

Most discussions acknowledge the significance of the research findings, highlighting how the discovery of virulence genes in commensal bacteria alters previous understanding.

I
Interest
 Moderate level of interest

Participants show moderate interest, with some posts emphasizing the novelty of gene clusters and potential implications for bacterial pathogenicity.

E
Engagement
 Moderate level of engagement

The discussions include references to specific gene systems and their roles, indicating a thoughtful engagement with the research data.

I
Impact
 Moderate level of impact

Several posts interpret the findings as impactful, suggesting they could influence future research directions or clinical considerations regarding bacterial behavior.

Social Mentions

YouTube

2 Videos

Twitter

4 Posts

Metrics

Video Views

335

Total Likes

20

Extended Reach

80,249

Social Features

6

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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Expanding Knowledge of Virulence Genes in Human Throat Bacteria

Expanding Knowledge of Virulence Genes in Human Throat Bacteria

This lecture explores four commensal Neisseria species from human throats, revealing new virulence gene clusters, secretion systems, and DNA transfer mechanisms that expand their gene repertoire and suggest potential pathogenic capabilities.

Lori A. S. Snyder

April 15, 2021

126 views

  • Dr. Alexander Carreño G.
    @ChemistryandBi1 (Twitter)

    RT @MicrobioSoc: Virulence genes and previously unexplored gene clusters in four #commensal Neisseria spp. isolated from the human throat e…
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    October 27, 2020

    5

  • BSMT
    @Micro_BSMT (Twitter)

    RT @MicrobioSoc: Virulence genes and previously unexplored gene clusters in four #commensal Neisseria spp. isolated from the human throat e…
    view full post

    October 27, 2020

    5

  • Alexander Carreño G.
    @Alexandernikko (Twitter)

    RT @MicrobioSoc: Virulence genes and previously unexplored gene clusters in four #commensal Neisseria spp. isolated from the human throat e…
    view full post

    October 27, 2020

    5

  • Microbiology Society
    @MicrobioSoc (Twitter)

    Virulence genes and previously unexplored gene clusters in four #commensal Neisseria spp. isolated from the human throat expand the neisserial gene repertoire. Find out more in #MGen @DrLoriSnyder. https://t.co/eEHu9i2MVT https://t.co/G2F2byFB9j
    view full post

    October 27, 2020

    12

    5

Abstract Synopsis

  • The study examines four commensal Neisseria spp from human throats, revealing new gene clusters related to virulence, secretion systems, and DNA transfer mechanisms that expand the known gene repertoire of these bacteria.
  • Researchers identified unique gene systems such as a Type VI Secretion System, a novel CRISPR system, and a Type IV Secretion System, along with capsule and haem utilization genes, some of which are similar to pathogenic strains.
  • These findings suggest that commensal bacteria possess a versatile gene pool that includes virulence-related genes, highlighting the potential for gene transfer and the importance of further exploring their functions in bacterial ecology and pathogenicity.]