N Engl J Med October 2020 PMID 32865374

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation.

Ken Okumura, Masaharu Akao, Tetsuro Yoshida, Masahito Kawata, Osamu Okazaki, Shintaro Akashi, Kenichi Eshima, Kimihiko Tanizawa, Masayuki Fukuzawa, Takuya Hayashi, Masahiro Akishita, Gregory Y H Lip, Takeshi Yamashita

Mentions

223
Peak: 79 in Oct 2020
across 5 sources since Sep 2020

Extended reach

1,776,138
potential audience

Total likes

468

Video views

3,507

Mentions per month

Sep 2020 – Sep 2025

Where it's discussed

  • X / Twitter194 posts
  • News15 articles
  • Facebook9 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions highlight the study's findings regarding the effectiveness of 15mg edoxaban in preventing stroke and systemic embolism in patients over 80, often referencing its lower risk of major bleeding compared to standard doses. Phrases like 'superior to placebo' and 'high-risk patients' illustrate the urgency and excitement within the discussions, reinforcing the transformative potential this research holds for elderly patient care.

AgreementStrong agreement

The discussions largely express strong agreement with the findings of the study, emphasizing its relevance for treatment strategies in elderly patients.

InterestHigh interest

Participants show a high level of curiosity about the implications of low-dose edoxaban for elderly patients, reflecting its significance in clinical practice.

EngagementModerate engagement

While many participants engage with the content, the depth of discussion is somewhat moderate, often focusing on summarizing findings without delving deeper into methodology or broader implications.

ImpactHigh impact

There is a consensus among participants that the publication has significant implications for clinical practice, particularly in reducing stroke risk in high-risk elderly patients.

Abstract in brief

  • The study assessed the effectiveness and safety of a low 15mg dose of edoxaban versus placebo in elderly patients (80+) with atrial fibrillation, focusing on those at risk of stroke but not suitable for standard anticoagulant doses.
  • The primary goal was to compare rates of stroke or systemic embolism (efficacy) and major bleeding events (safety).
  • Results showed that edoxaban significantly reduced stroke risk but was associated with higher gastrointestinal bleeding compared to placebo, while the overall mortality rates were similar in both groups.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 115 likes · 44 shares · 936,213 followers View post →
MAX@病院薬剤師
@pharmax9 · X

【定期】アピキサバン2.5mg1日1回にするくらいなら、エドキサバン15mg1日1回にしろって言ってるんだよォ! ※高齢、心房細動の方の話 https://t.co/eNsD9b415P

Jul 4, 2023 · 37 likes · 1 share · 1,564 followers View post →
Prof Dhiraj Gupta
@DhirajGuptaBHRS · X

Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of stroke/SE/ mortality with no addl risk of ICH Higher risk of GI bleed https://t.co/Io1HZrthrB https://t.co/XcFro8q1G1 https://t.co/SHDqswmcqY

Oct 30, 2020 · 33 likes · 9 shares · 4,972 followers View post →
だるべ(腎臓内科)
@Darbepoeti_n · X

「超高齢者に抗凝固療法を行うべきか」については不明な点が多い。この研究で、低用量エドキサバン(15mg)は ✓80歳以上の日本人 ✓出血を増やさずに、脳梗塞を予防する ことがわかった。添付文章では許されていませんが、僕は高齢者にこの容量で処方することがあります https://t.co/PqmL5NJUqt https://t.co/sGwYhoNMHw

Nov 5, 2020 · 20 likes · 3 shares · 9,597 followers View post →
Caio de Assis Moura Tavares
@caiodeamtavares · X

1/15 Since the publication of the ELDERCARE-AF in NEJM (https://t.co/bJtTZkPksc), I have seen a lot of residents and colleagues talking that “low dose” anticoagulation is the solution for older frail patients at high bleeding risk. That an “intermediate” dose would be the best

Oct 31, 2020 · 17 likes · 3 shares · 351 followers View post →
Derek Leong
@Derek_Leong_RPh · X

ELDERCARE-AF: In Pts >80 y.o. with non-valvular AF, CHADS2 >1, unable to take OAC at approved doses, edoxaban 15 mg/d ⬇️stroke/systemic embolism vs. placebo (ARR 4.4%/year). ⬆️Bleeding with edoxaban, esp. GI bleed (ARI 1.5%/year), CRNMB (ARI 5.6%/year). https://t.co/jpxIcayR6t https://t.co/QvuV3hOnjb

Sep 24, 2020 · 15 likes · 3 shares · 1,560 followers View post →

All mentions

Mar家庭医
@gene_fam_aura · X

超高齢者のAFに対する低用量エドキサバン(リクシアナ)の有効性について ・80歳以上、CHADS2スコア2点以上、かつ標準的な抗凝固療法(ワルファリンや通常量DOAC)が不適切とされた非弁膜症性AF患者984例が対象 ・介入群ではエドキサバン15mg/dayを投与 https://t.co/VR7gbgZHA4

Sep 25, 2025 · 113 followers View post →
にゃんでもにゃ医
@lE9BrvyUwLLVZIE · X

@TT58852391 こちらの有名なリクシアナ15mgのRCTは平均年齢86歳のようでした

May 31, 2025 · 8 likes · 5,997 followers View post →
kakugari_pharmacist
@kakugaripharma · X

今日のモヤり そば先生とも会議。 これを脳梗塞の二次予防として外挿してよい? under dose案件? https://t.co/wrPnOioekC

Apr 30, 2025 · 4 likes · 632 followers View post →
Emily McDonald
@DrEmilyMcD · X

RT @itraslan: @DrEmilyMcD Not that I use Edox often, but the dosing flexibility studied in RCTs is really helpful for shared decision makin…

Jul 15, 2024 · 1 share · 2,757 followers View post →
Ismail Raslan
@itraslan · X

@DrEmilyMcD Not that I use Edox often, but the dosing flexibility studied in RCTs is really helpful for shared decision making can even push down to 15mg https://t.co/Ro6w1Y85rE

Jul 14, 2024 · 4 likes · 1 share · 522 followers View post →
(仮称)hanzou1121
@hanzou1121 · X

@Ryu04196650Ryu 最近はその辺のアンテナ乏しいので僕も明確に答えれないのですが、低容量で質が高い予防効果を狙うとなるedoxabanが高位に上がってくる認識です。あとは総合的な選択をするしかないのでしょうね。あとは参考指標とて既報からNNHを自力で算出するしかないのかもです。 https://t.co/7cZt9xn7C2

Dec 25, 2023 · 1 like · 733 followers View post →
にいやん
@niiyan51 · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/DmgyixM5Xy

Dec 15, 2023 · 1,077 followers View post →
Su(Matt)riptan
@Ambcare_pharmer · X

@michael22joseph @DHidlayVIR @EzraTeitelbaum Not a periop study, but recent study that gets at some of these questions is eldercare-af. Low dose doac vs placebo in patients generally considered not eligible for OAC. https://t.co/v0BqNBbJcm

Jul 25, 2023 · 2 likes · 15 followers View post →
横山暁子
@yokoakipp · X

RT @pharmax9: 【定期】アピキサバン2.5mg1日1回にするくらいなら、エドキサバン15mg1日1回にしろって言ってるんだよォ! ※高齢、心房細動の方の話 https://t.co/eNsD9b415P

Jul 5, 2023 · 1 share · 1,113 followers View post →
MAX@病院薬剤師
@pharmax9 · X

【定期】アピキサバン2.5mg1日1回にするくらいなら、エドキサバン15mg1日1回にしろって言ってるんだよォ! ※高齢、心房細動の方の話 https://t.co/eNsD9b415P

Jul 4, 2023 · 37 likes · 1 share · 1,564 followers View post →
パン焦がし薬剤師(やっちゃん)@牡丹山薬局
@yo_ishii_2021 · X

『⽇本⼈超⾼齢者における⼼房細動に対する低⽤量エドキサバンの有⽤性』 https://t.co/k07i5FpTto https://t.co/cmSYpWQqca

Apr 3, 2023 · 3 likes · 2,322 followers View post →
Xenophon Costeas - Ξενοφών Κωστέας
@XCosteas · X

RT @DrJasonAndrade: @RhythmHelp @drraviele @DrMarthaGulati @guroledip @cpgale3 @LuigiDiBiaseMD @TJaredBunch @SeguraCardio @PrashSanders @SA…

Nov 28, 2022 · 2 shares · 417 followers View post →
Luigi Di Biase
@LuigiDiBiaseMD · X

RT @DrJasonAndrade: @RhythmHelp @drraviele @DrMarthaGulati @guroledip @cpgale3 @LuigiDiBiaseMD @TJaredBunch @SeguraCardio @PrashSanders @SA…

Nov 28, 2022 · 2 shares · 8,550 followers View post →
Jason Andrade
@DrJasonAndrade · X

@RhythmHelp @drraviele @DrMarthaGulati @guroledip @cpgale3 @LuigiDiBiaseMD @TJaredBunch @SeguraCardio @PrashSanders @SABOURETCardio @mmamas1973 @gonzaeperez @ShelleyZieroth @Dr_Santangeli @JonPicciniSr @GiuseppeGalati_ We have that with eldercare. Though that assumes 2.5 bud of Apixaban is similar to edoxaban 15 https://t.co/p0rALtn40l

Nov 28, 2022 · 3 likes · 2 shares · 8,011 followers View post →
色々自粛中(ガラス細工の様な繊細なハートを持つ貴公子
@ECGEPSCADEVICE · X

RT @tororo__ph:

Sep 29, 2022 · 1 share · 9,385 followers View post →
Tororo_ph@EP Univ. oshademic
@tororo__ph · X

Sep 29, 2022 · 6 likes · 1 share · 6,787 followers View post →
ダックス医
@DachsClinic · X

循環器メモ:超高齢者へのDOAC投与 結論:リクシアナ15は日本発のエビデンスあり ELDER-CARE AF試験はDOAC躊躇しがちな、80歳以上の患者にエドキサバンとプラセボを比較したもの。ワーファリンとの比較でなくプラセボとの比較なのが珍しい。 続 https://t.co/slhcLzxPfA

Aug 16, 2022 · 9 likes · 19,234 followers View post →
ひそくちん
@E_hisoku · X

RT @Yohei_Kanzawa: そしてECSが盛り上がってるんですね。 超高齢者のAF、少量エドキサバン(リクシアナ)vsプラセボ。 日本から! #心房細動 #DOAC Low-Dose Edoxaban in Very Elderly Patients with Atr…

Jul 28, 2022 · 3 shares · 155 followers View post →
Journal of the Indian Academy of Geriatrics
@JIAGOfficial · X

An interesting and relevant study population selection by the ELDERCARE-AF group Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/fx9e0qQTLc

May 24, 2022 · 1 like · 136 followers View post →
Yousef Fazel
@YouseffazelMD · X

RT @muddasir_ayazMD: GI is often asked about resumption of anticoagulation as a binary (yes/no) We owe it to our patients to be aware of e…

May 6, 2022 · 1 share · 160 followers View post →
Muddasir Ayaz
@TheGastrologer · X

GI is often asked about resumption of anticoagulation as a binary (yes/no) We owe it to our patients to be aware of emerging data to make more nuanced recommendations Data like

May 6, 2022 · 6 likes · 1 share · 1,167 followers View post →
ときヲ
@toki_wo_koe · X

the ELDERCARE-AF これ好きです。 ばあさん(享年95歳)はエドキサバン15mg飲んでました。 親父殿は、早々に筆頭著者に焼いてもらうべきでした。紹介状は持っていたのに... Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/YOVw9fxfeK

Apr 20, 2022 · 2 likes · 2,589 followers View post →
アルココ
@aruko_koko · X

https://t.co/KLSOJ6icZd

Apr 13, 2022 · 694 followers View post →
ちゃおせん
@EzmkN1 · X

@mackey_yo 高齢者に対してきめ細かく抗凝固薬を調整できないかとの試みも平行して検討されています。 あ、ASA+DOACは避けるべきです。同意です。しかし循環器疾患を合併している場合や高度症候性ICSの場合は本人と家族と相談して処方するしかないかと忸怩たる思いです https://t.co/BV877Cx4bS

Apr 9, 2022 · 2,512 followers View post →
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X

RT @taora_bokujun: この話と思います 論文開きながら視聴できるのはWebのよさかも #22JCS https://t.co/dlXMhyYbfJ

Mar 10, 2022 · 2 shares · 14,787 followers View post →
日本循環器学会 情報広報部会
@JCIRC_IPR · X

RT @taora_bokujun: この話と思います 論文開きながら視聴できるのはWebのよさかも #22JCS https://t.co/dlXMhyYbfJ

Mar 10, 2022 · 2 shares · 22,133 followers View post →
柴田啓佑 循環器内科
@taora_bokujun · X

この話と思います 論文開きながら視聴できるのはWebのよさかも #22JCS https://t.co/dlXMhyYbfJ

Mar 10, 2022 · 4 likes · 2 shares · 838 followers View post →
ガラパゴス伊藤@総合診療医
@galapagos_ito · X

リクシアナ15mgで使えるようになって嬉しいけど、プラセボとの比較なんだな。 他のDOACが基本ワーファリンとの非劣勢だから戦っている相手が違うことは認識必要。リクシアナ15mgは飲まないよりはマシくらいの感じ。 https://t.co/9U7QVxuzka

Dec 20, 2021 · 1 like · 2,398 followers View post →
あずーる@Azule
@Anazuresky2 · X

RT @Fizz_DI: 80歳以上でCHADS2≧2のNVAFに対するエドキサバン15mg/日 vs プラセボ(n=984、日本) ・脳卒中or全身性塞栓症 2.3%/年 vs 6.7%/年 HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3%/年 vs…

Dec 6, 2021 · 3 shares · 5,530 followers View post →
medical user
@UserMedical · X

RT @Fizz_DI: 80歳以上でCHADS2≧2のNVAFに対するエドキサバン15mg/日 vs プラセボ(n=984、日本) ・脳卒中or全身性塞栓症 2.3%/年 vs 6.7%/年 HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3%/年 vs…

Dec 6, 2021 · 3 shares · 93 followers View post →
Tororo_ph@EP Univ. oshademic
@tororo__ph · X

RT @Fizz_DI: 80歳以上でCHADS2≧2のNVAFに対するエドキサバン15mg/日 vs プラセボ(n=984、日本) ・脳卒中or全身性塞栓症 2.3%/年 vs 6.7%/年 HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3%/年 vs…

Dec 5, 2021 · 3 shares · 6,787 followers View post →
Fizz-DI@比較と使い分け-KOJIMA Yushi
@Fizz_DI · X

80歳以上でCHADS2≧2のNVAFに対するエドキサバン15mg/日 vs プラセボ(n=984、日本) ・脳卒中or全身性塞栓症 2.3%/年 vs 6.7%/年 HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3%/年 vs 1.8%/年 HR=1.87 [95%CI:0.90-3.89] N Engl J Med.383(18):1735-45,(2020) PMID:32865374 https://t.co/7qNVepNNTF

Dec 5, 2021 · 12 likes · 3 shares · 34,460 followers View post →
DrVeins
@drgarcivenas · X

@caperubono @Fosfolamban Mira así publican los japoneses a los que si les interesa la ciencia y la salud de los pacientes. https://t.co/zIkShcDpEP

Nov 23, 2021 · 1 like · 5,054 followers View post →
Western GIM Bison
@BisonGIM · X

RT @rahimkachra: Top 5 papers at #RMIM21 via Dr M Prystajecky. 4/5: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation @N…

Nov 19, 2021 · 1 share · 45 followers View post →
Rahim Kachra
@rahimkachra · X

Top 5 papers at #RMIM21 via Dr M Prystajecky. 4/5: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation @NEJM @RockyMtnIM https://t.co/i6bcsFNcvE

Nov 18, 2021 · 5 likes · 1 share · 1,060 followers View post →
pinacol
@pinacol · X

【S54-1】あとはエドキサバンの例の論文。https://t.co/PmA0d5beuI #jsphcs2021

Oct 24, 2021 · 1,616 followers View post →
ときヲ
@toki_wo_koe · X

エドキサバン15mgの承認が少し経ちますELDERCARE-AFって結構面白くて ①半分ぐらい抗血小板薬併用 ②これまでは渋々30mgを飲んでいたであろう患者群。 OAC単剤と+SAPT群で層別化して欲しい。 Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/nFFwj7kN05

Sep 16, 2021 · 1 like · 2,589 followers View post →
TOMO@北の薬屋®
@kitanokusuriya · X

memoとして貼っておく ELDERCARE-AF https://t.co/Hu4SugMwEV https://t.co/iTMyLfXkKi

Sep 9, 2021 · 2 likes · 4,650 followers View post →
鯵ゼミ_Journal Club
@AJSR_since2005 · X

#026 Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation N Engl J Med 2020; 383:1735-1745

Sep 4, 2021 · 6 followers View post →
くに
@daipc0203 · X

RT @Fizz_DI: CHADS2スコア≧2、80歳以上の日本人高齢者に対するエドキサバン15mg/日の有効性と安全性。 (年間発生率) ・塞栓症の複合 2.3% vs 6.7%:HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3% vs 1.8%:HR…

Sep 2, 2021 · 1 share · 19 followers View post →
Fizz-DI@比較と使い分け-KOJIMA Yushi
@Fizz_DI · X

CHADS2スコア≧2、80歳以上の日本人高齢者に対するエドキサバン15mg/日の有効性と安全性。 (年間発生率) ・塞栓症の複合 2.3% vs 6.7%:HR=0.34 [95%CI:0.19-0.61] ・大出血 3.3% vs 1.8%:HR=1.87 [95%CI:0.90-3.89] N Engl J Med.383(18):1735-45,(2020) PMID:32865374 https://t.co/7qNVepvEFx

Sep 2, 2021 · 9 likes · 1 share · 34,460 followers View post →
たけちゃん
@nitrotake · X

エドキサバンの15mg低用量の試験。 vsプラセボで、出血リスクHR1.87; 95%CI 0.90〜3.89; P = 0.09 リスクは上がらない可能性があるかもって感じ? 第一三共のかな? https://t.co/aM1oQ3gjes

Aug 5, 2021 · 3 likes · 1,442 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

やはり何度読み返しても、センスよいCQの論文だよなぁ。https://t.co/a0YJwLnIFK 確かに、標準⽤量のDOACが使⽤できない⾼齢者に対する抗凝固療法は、これまで臨床上未解決な問題であったと言ってもよい

Mar 13, 2021 · 13 likes · 1 share · 8,604 followers View post →
在野の臨床医
@LLL_physician · X

80歳以上の心房細動患者に、エドキサバン低用量投与すると、プラセボと比べて脳卒中および全身塞栓症の発症が少なく、大出血は多い傾向にある。Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/ARWTw8nOLy

Feb 15, 2021 · 1 like · 2 followers View post →
ウハクリニックまで何年かかるのだろう
@keitan0628 · X

RT @Darbepoeti_n: 「超高齢者に抗凝固療法を行うべきか」については不明な点が多い。この研究で、低用量エドキサバン(15mg)は ✓80歳以上の日本人 ✓出血を増やさずに、脳梗塞を予防する ことがわかった。添付文章では許されていませんが、僕は高齢者にこの容量で…

Jan 21, 2021 · 3 shares · 371 followers View post →
movedoc
@movedoc · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/GBjCXNFRlA

Jan 13, 2021 · 486 followers View post →
Dr.猫太郎
@Dr_mew_resident · X

RT @Yohei_Kanzawa: そしてECSが盛り上がってるんですね。 超高齢者のAF、少量エドキサバン(リクシアナ)vsプラセボ。 日本から! #心房細動 #DOAC Low-Dose Edoxaban in Very Elderly Patients with Atr…

Jan 1, 2021 · 3 shares · 97 followers View post →
ときヲ
@toki_wo_koe · X

大往生した祖母を偲んで思い出した試験。婆さん、15mg飲んでてやっぱよかったペーぞ!!元気でな〜(あの世で) ELDERCARE-AF 試験 Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation  The New England Journal of Medicine(日本国内版) https://t.co/2vvWezcsZi

Dec 25, 2020 · 6 likes · 2,589 followers View post →
Metabolic Health Digest
@methealthdigest · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation Read more: https://t.co/FsbmD6385L #metabolicsyndrome #metabolichealthdigest #hypertension #hypertensionawerness #highbloodpressure #highbloodpressureproblems https://t.co/wPDTV6nxIJ

Dec 18, 2020 · 10 followers View post →
Tiphaine Lenfant
@TiphaineLft · X

3) Edoxaban chez les patients > 80 ans en FA non valvulaire

Dec 9, 2020 · 320 followers View post →
GeriMedJC
@GeriMedJC · X

Next up on #GeriMedJC, @NEJM Eldercare-AF Trial: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/GBeehYPZAq

Nov 27, 2020 · 2,068 followers View post →
OlgaDunaeva
@DunyaOlga · X

RT @GeriMedJC: Tune into #GeriMedJC on Nov 27 at 08:00 AM ET via Zoom: https://t.co/10EKfkm5Cg Low-Dose Edoxaban in Very Elderly Patients w…

Nov 26, 2020 · 2 shares · 193 followers View post →
dov gandell
@dellightd · X

RT @GeriMedJC: Tune into #GeriMedJC on Nov 27 at 08:00 AM ET via Zoom: https://t.co/10EKfkm5Cg Low-Dose Edoxaban in Very Elderly Patients w…

Nov 26, 2020 · 2 shares · 92 followers View post →
GeriMedJC
@GeriMedJC · X

Tune into #GeriMedJC on Nov 27 at 08:00 AM ET via Zoom: https://t.co/10EKfkm5Cg Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation. https://t.co/GBeehYPZAq

Nov 26, 2020 · 2 likes · 2 shares · 2,068 followers View post →
David Henry
@davidhenrymd · X

Full-dose anticoagulation is often used in a fib patients, but carries a risk of bleeding. This study shows that lower dose anticoagulation w/ edoxaban could accomplish the same stroke/heart attack prevention & lower the risk of bleeding for elderly pts https://t.co/7S46Y8RSir https://t.co/ubDbSdIfK5

Nov 25, 2020 · 2 likes · 2,320 followers View post →
内田
@uchida_kawasaki · X

RT @hichachu: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation 「超高齢心房細動患者における低用量エドキサバンの有効性と安全性の検討」 https://t.co/S44uTgt…

Nov 21, 2020 · 1,930 followers View post →
ニューロドクター乱夢
@hichachu · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation 「超高齢心房細動患者における低用量エドキサバンの有効性と安全性の検討」 https://t.co/S44uTgtOBS

Nov 20, 2020 · 4,258 followers View post →
ニューロドクター乱夢
@hichachu · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/fXEAu5lGsF

Nov 20, 2020 · 4,258 followers View post →
SWDK
@sA0mJBMAA4snqUf · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/valwi1p0sD

Nov 20, 2020 · 15 followers View post →
Royal College of General Practitioners
@rcgp · X

Have you read our new Essential Knowledge Update Journal Watch? It offers the latest clinical knowledge on topics including heart failure with reduced ejection fraction and low-dose edoxaban in very elderly patients with atrial fibrillation: https://t.co/H9wer5OVOc https://t.co/BstHey1qY8

Nov 19, 2020 · 81,361 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 7, 2020 · 44 shares · 3,779 followers View post →
だるべ(腎臓内科)
@Darbepoeti_n · X

「超高齢者に抗凝固療法を行うべきか」については不明な点が多い。この研究で、低用量エドキサバン(15mg)は ✓80歳以上の日本人 ✓出血を増やさずに、脳梗塞を予防する ことがわかった。添付文章では許されていませんが、僕は高齢者にこの容量で処方することがあります https://t.co/PqmL5NJUqt https://t.co/sGwYhoNMHw

Nov 5, 2020 · 20 likes · 3 shares · 9,597 followers View post →
Antonio Manteca
@amango30 · X

RT @RevistaMFSamfyc: Edoxaban a dosis bajas en pacientes muy mayores con fibrilación auricular https://t.co/FiPqi8Z4dp PMID 32865374

Nov 5, 2020 · 1 share · 138 followers View post →
Revista MFAndalucia
@RevistaMFSamfyc · X

Edoxaban a dosis bajas en pacientes muy mayores con fibrilación auricular https://t.co/FiPqi8Z4dp PMID 32865374

Nov 5, 2020 · 1 like · 1 share · 723 followers View post →
通りすがりの麻酔科医
@torisugari_anes · X

https://t.co/VdV041Jj7D 80歳以上の日本人の非弁膜症性afに対するエドキサバンの効果を調べたRCT 結果は脳梗塞or全身性塞栓症の発生率は、介入群で2.3%、対照群で6.7%だった(HR:0.34[0.19-0.61])出血発生率は実質的に介入群で多かった(3.3%vs1.8%;HR:1.87[0.90-3.89]) #当麻_凝固

Nov 5, 2020 · 2,035 followers View post →
Higinio
@curabellas · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 5, 2020 · 44 shares · 1,046 followers View post →
James
@James51650277 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 4, 2020 · 44 shares · 13 followers View post →
Eileen Burns
@EileenBurns13 · X

RT @YoungGeris: Great to see research in over 80s in the @NEJM , albeit with the outdated phrase 'elderly' in the title. https://t.co/vZZI…

Nov 3, 2020 · 1 share · 2,860 followers View post →
Moisés Sánchez
@sgmoise · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/hFBj5GaJLO

Nov 3, 2020 · 198 followers View post →
Young Geris (irony intended)
@YoungGeris · X

Great to see research in over 80s in the @NEJM , albeit with the outdated phrase 'elderly' in the title. https://t.co/vZZI5ZijYS

Nov 3, 2020 · 11 likes · 1 share · 5,162 followers View post →
Kevin K. Chung, MD
@chungk1031 · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/g8eybBsgWb

Nov 2, 2020 · 4 likes · 14,099 followers View post →
Carlos E. Goicochea
@Carlos_E_Goico · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 2, 2020 · 44 shares · 31 followers View post →
Pankti Pandya
@pankti4299 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 2, 2020 · 44 shares · 2,163 followers View post →
Salud juntos
@alfonso_casi · X

En japoneses ≥80 años con fibrilación auricular no valvular no candidatos a anticoagulantes orales, 15 mg de edoxabán/día fue superior al placebo en la prevención de ACVs o embolia sistémica, sin aumento significativo hemorragia mayor vs. placebo. https://t.co/yIT1iW9BFP

Nov 2, 2020 · 1 like · 8,568 followers View post →
Simone Biscaglia
@SimoneBiscaglia · X

RT @caiodeamtavares: 1/15 Since the publication of the ELDERCARE-AF in NEJM (https://t.co/bJtTZkPksc), I have seen a lot of residents and c…

Nov 1, 2020 · 3 shares · 4,764 followers View post →
Ricardo
@ricardoconsua · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 1, 2020 · 44 shares · 231 followers View post →
[{MAVERICK}]
@Moileon2019 · X

Okumura K, Akao M, Yoshida T, et al.; ELDERCARE-AF Committees and Investigators. Low-dose edoxaban in very elderly patients with atrial fibrillation. N Engl J Med. 2020; 383: 1735-45. #LowDose #Edoxaban #VeryElderlyJapanesePatients #NonValvularAtrialFibri…https://t.co/YMMYcYEtOV

Nov 1, 2020 · 94 followers View post →
Alexandre Anderson de Sousa Munhoz Soares
@Alexandre_ASMS · X

RT @caiodeamtavares: 1/15 Since the publication of the ELDERCARE-AF in NEJM (https://t.co/bJtTZkPksc), I have seen a lot of residents and c…

Nov 1, 2020 · 3 shares · 85 followers View post →
Emer Jean
@EmerJean1 · X

5/5 Dans la fibrillation auriculaire du sujet âgé, l’edoxaban à faible dose est supérieur au placebo et ne provoque pas plus de saignement https://t.co/Aq4cACFzSQ

Nov 1, 2020 · 6 followers View post →
ERICK J. VAZQUEZ
@MDErickvzqz · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 1, 2020 · 44 shares · 154 followers View post →
Inspira Health
@InspiraHealth1 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Nov 1, 2020 · 44 shares · 231 followers View post →
Caio de Assis Moura Tavares
@caiodeamtavares · X

1/15 Since the publication of the ELDERCARE-AF in NEJM (https://t.co/bJtTZkPksc), I have seen a lot of residents and colleagues talking that “low dose” anticoagulation is the solution for older frail patients at high bleeding risk. That an “intermediate” dose would be the best

Oct 31, 2020 · 17 likes · 3 shares · 351 followers View post →
Felice Gragnano
@FeliceGragnano · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 31, 2020 · 9 shares · 5,368 followers View post →
Thomas Jared Bunch
@TJaredBunch · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 31, 2020 · 9 shares · 6,751 followers View post →
Tomos Walters
@fitzroytomos · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 31, 2020 · 9 shares · 587 followers View post →
Alex Bowles
@AlexB_Pharm · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 384 followers View post →
Jack Pluenneke
@JackPluenneke · X

https://t.co/RwVimbUbXm

Oct 31, 2020 · 787 followers View post →
南郷 栄秀/Eishu NANGO, MD, PhD
@enango · X

https://t.co/QeQFqQe9d0 https://t.co/7Ip36I8Wui

Oct 31, 2020 · 3,017 followers View post →
Nash_Creative
@NashCreative1 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 550 followers View post →
Majo Suing
@Majis171 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 125 followers View post →
Kashif Chaudhry
@KashifMD · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 51,851 followers View post →
Euri Rivas
@euri_rivas · X

RT @vic_pallares:

Oct 31, 2020 · 2 shares · 48 followers View post →
NeuroIR
@neuro_ir · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 825 followers View post →
Trung Nguyen
@drtrungnguyen · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 1,395 followers View post →
Carlos Boyzo
@CarlosBoyzo10 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 31, 2020 · 44 shares · 116 followers View post →
Electrophysiology Nurse Specialist
@g_arrhythmia · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 34 followers View post →
Ivan Mendoza
@mencardio · X

RT @vic_pallares:

Oct 30, 2020 · 2 shares · 7,254 followers View post →
EM2025
@em_em2025 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 233 followers View post →
Umar Shakur
@u_shakur · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 293 followers View post →
Michelle Wood
@Mwoodspain · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 189 followers View post →
daniele.pastori
@daniele_pastori · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 82 followers View post →
Dr H. Mohamed
@moh_warbuffet · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 231 followers View post →
Abel Torrelles Fortuny
@abel_torrelles · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 167 followers View post →
猫になりたい薬剤師
@Vannyamoto · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 1,046 followers View post →
Mr Anonymous
@WLancsGP · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 906 followers View post →
Prash Sanders
@PrashSanders · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 9,222 followers View post →
Bil Kirmani
@drkirmani · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 2,000 followers View post →
AF Association
@AtrialFibUK · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 5,257 followers View post →
Lynsey Fielden
@lynseyfielden1 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 388 followers View post →
Frank Lindemann
@FrankLindemann3 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 562 followers View post →
Liverpool Centre for Cardiovascular Science
@LiverpoolCCS · X

RT @DhirajGuptaBHRS: Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of…

Oct 30, 2020 · 9 shares · 1,474 followers View post →
Gray Wolf
@GreyWol27926578 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 164 followers View post →
Prof Dhiraj Gupta
@DhirajGuptaBHRS · X

Practice changing study @NEJM In elderly AF pts with contraindications to OAC, Edoxaban 15mg reduces composite of stroke/SE/ mortality with no addl risk of ICH Higher risk of GI bleed https://t.co/Io1HZrthrB https://t.co/XcFro8q1G1 https://t.co/SHDqswmcqY

Oct 30, 2020 · 33 likes · 9 shares · 4,972 followers View post →
Marco Paladino
@m_pala96 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 56 followers View post →
Airiau Caroline
@caroairiau · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 1,472 followers View post →
Peter Schellongowski
@Schellongowski · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 487 followers View post →
Jose Daniel Mosquera Lozano
@jdmosqueral · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 233 followers View post →
Rosa Martínez
@mtnez_rosa · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 128 followers View post →
Dr Khalid
@rauf_khalid · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 2,486 followers View post →
Gabriela
@DraGabiCampos · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 382 followers View post →
PD⚕⚖️
@pamedr15 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 403 followers View post →
lizzet
@lizzet_neftis · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 20 followers View post →
Wafaa Bin Ali
@MsBinAli · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 814 followers View post →
Kevin Daniel
@kevdaniel10 · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 153 followers View post →
Kyle James
@1kylejam · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 37 followers View post →
Ali S. Raja, MD
@AliRaja_MD · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 143,266 followers View post →
Pub Health Monitor
@monitor_PH · X

RT @NEJM: Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 44 shares · 1,824 followers View post →
NEJM
@NEJM · X

Visual Abstract: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Oct 30, 2020 · 115 likes · 44 shares · 936,213 followers View post →
@investigando
@rocatanho · X

En pac muy ancianos c/FA no valv no candidatos para dosis estándar de ACO, una dosis de 15 mg una vez al día de edoxaban sería superior a placebo previniendo el ictus o el embolismo sistémico y no resultaría en una mayor incidencia de sangrado mayor https://t.co/aLJJqTuIyJ

Oct 29, 2020 · 398 followers View post →
Alan Dow
@alan_dow · X

A touch of Edox? In 80+ year olds with non-valvular Afib and at high-risk for anti-coagulation, half-dose Edoxaban cuts stroke risk by 2/3s with no change in mortality. Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/NgZuHmS8Q4

Oct 29, 2020 · 877 followers View post →
Vicente Pallares
@vic_pallares · X

Oct 29, 2020 · 2 likes · 2 shares · 5,418 followers View post →
Unya S
@UnyaS · X

RT @drjohnmorley: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/X1RPWG5vqg

Oct 29, 2020 · 1 share · 186 followers View post →
john morley
@drjohnmorley · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/X1RPWG5vqg

Oct 29, 2020 · 2 likes · 1 share · 8,310 followers View post →
Shibley
@dr_shibley · X

RT @GiusepeBellelli: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/bxNmC8X9iE

Oct 29, 2020 · 1 share · 27,500 followers View post →
Giuseppe Bellelli
@GiusepeBellelli · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/bxNmC8X9iE

Oct 29, 2020 · 1 like · 1 share · 1,194 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/W5QufGsG5Q

Oct 29, 2020 · 1 like · 2,716 followers View post →
雪むかえー脳神経内科/医学英語
@YukimukaeMemo · X

【気になった論文】 NEJMより,80歳以上のNVAFに対するLow-Dose Edoxabanの二重盲検プラセボ比較試験.日本からの報告. いずれはNVAFに対するEdoxaban15mgも適応になるのだろうか… https://t.co/rP5pd7bDC6

Oct 28, 2020 · 432 followers View post →
HN
@nagano_1123 · X

CHADS2≧2で抗凝固薬の通常使用に不適切と考えられた80歳以上のAf患者をエドキサバン15mgとplaceboを比較した日本発のRCT. Stroke+全身塞栓は2.3% vs 6.7%(HR 0.34 CI 0.19-0.61)、major bleedingは3.3% vs 1.8%(HR 1.87 CI 0.90-3.89). https://t.co/WGcPWsplRP

Oct 28, 2020 · 2 likes · 5,331 followers View post →
Ernesto Rodríguez H
@ernestocardio · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/yS2yfMcoHP

Oct 28, 2020 · 1 like · 2,215 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

"...In very elderly Japanese patients with NVAF who were not appropriate candidates for standard doses of OAC, a once-daily 15-mg dose of edoxaban was superior to placebo in preventing stroke or systemic embolism, without more major bleedings..." https://t.co/LwU1BUA5TQ https://t.co/Fi4vUYYRXl

Oct 28, 2020 · 1 like · 12,173 followers View post →
antonio ramon muñoz
@armunyoz · X

RT @rincondesisifo: (2 minute medicine) El edoxabán a dosis BAJAS previene los ACV en pac ancianos con FA https://t.co/rW3ibPHPa6 REC de E…

Oct 25, 2020 · 4 shares · 1,390 followers View post →
Mohamed Shiha
@Mo_Shiha · X

RT @RichardPollok: Also consider low dose Edoxaban in elderly with AF https://t.co/hic1jdQjvX

Oct 24, 2020 · 1 share · 831 followers View post →
Prof Richard Pollok
@RichardPollok · X

Also consider low dose Edoxaban in elderly with AF https://t.co/hic1jdQjvX https://t.co/697tb7Q6U1

Oct 24, 2020 · 3 likes · 1 share · 1,294 followers View post →
はぎ
@hagi220 · X

心房細動の非常に高齢の患者における低用量エドキサバン-PubMed https://t.co/AjRt7XuJnd https://t.co/Z3haS2WkSZ

Oct 24, 2020 · 493 followers View post →
pharmaciensAPES
@pharmaciensAPES · X

Étude japonaise de phase 3 concluant que l’edoxaban 15 mg par jour est >au placebo pour prévenir les incidents cardiovasculaires chez les 80 ans avec FA non-valvulaire, ayant des contre-indications aux doses usuelles d’anticoagulants en prévention de l’AVC https://t.co/dkABYUVpz8 https://t.co/V3xB8z5kX2

Oct 23, 2020 · 1 like · 896 followers View post →
Carmelo
@carmelprzrz · X

RT @rincondesisifo: (2 minute medicine) El edoxabán a dosis BAJAS previene los ACV en pac ancianos con FA https://t.co/rW3ibPHPa6 REC de E…

Oct 23, 2020 · 4 shares · 453 followers View post →
Omid Hakami Hakami
@Omidhakami · X

RT @rincondesisifo: (2 minute medicine) El edoxabán a dosis BAJAS previene los ACV en pac ancianos con FA https://t.co/rW3ibPHPa6 REC de E…

Oct 23, 2020 · 4 shares · 506 followers View post →
rincondesisifo
@rincondesisifo · X

(2 minute medicine) El edoxabán a dosis BAJAS previene los ACV en pac ancianos con FA https://t.co/rW3ibPHPa6 REC de ECA https://t.co/S63WGiITpl Estudio original https://t.co/sVvuhEqeGY

Oct 23, 2020 · 1 like · 4 shares · 8,453 followers View post →
Mohammed Abufarhaneh
@MAbufarhaneh · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/CdR7mXwbGa

Oct 22, 2020 · 234 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @StrokeAHA_ASA: Chaos About Treatment of Chaotic Heartbeat in Elderly Patients https://t.co/A8NOcuoQuj In this blog post, #BloggingStrok…

Oct 13, 2020 · 1 share · 2,149 followers View post →
Stroke AHA/ASA
@StrokeAHA_ASA · X

Chaos About Treatment of Chaotic Heartbeat in Elderly Patients https://t.co/A8NOcuoQuj In this blog post, #BloggingStroke contributor Nurose Karim discusses @NEJM article "Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation" #stroke https://t.co/FJR6hvoAK0

Oct 13, 2020 · 4 likes · 1 share · 37,451 followers View post →
Rubina Malik
@rubinamalikmd · X

RT @MontefioreGeri: REMINDER: #Geriatrics fellows' #journalclub this afternoon at 2PM! See you there! DM for Zoom link. #GeriMed Low-Dose…

Oct 8, 2020 · 1 share · 70 followers View post →
Montefiore Geriatrics
@MontefioreGeri · X

REMINDER: #Geriatrics fellows' #journalclub this afternoon at 2PM! See you there! DM for Zoom link. #GeriMed Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation @NEJM https://t.co/OraqKmCAN4

Oct 8, 2020 · 2 likes · 1 share · 288 followers View post →
Oliver Segal
@DrOliverSegal · X

Once daily 15mg edoxaban superior to placebo in preventing stroke or systemic embolism in ELDERCARE-AF rial and incidence of major bleeding not significantly higher. https://t.co/b2kHj74fEq

Oct 8, 2020 · 1 like · 1,360 followers View post →
@aroonsirimd@med-mastodon.com
@AroonsiriMD · X

Do you have older nonvalvular Afib >=80YO who can't take standard dose AC? @NEJM Try Edoxaban 15mg/day. Less stroke, no⬆️major bleeding vs placebo @TempleIM @aliachisty @PaulNWilliamz @JMAllenbaugh @jaimefine @LaReinaJay10 https://t.co/hR0SEfIyuC https://t.co/VXxvX5xQ3h

Oct 7, 2020 · 3 likes · 2,889 followers View post →
co
@co48466745 · X

低用量エドキサバンのエビデンスって、これかな? https://t.co/zD0dCzrnRo

Oct 7, 2020 · 311 followers View post →
perfectly misaligned
@sksicsicsic · X

RT @NEJM: Original Article: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation #ESCCongress

Oct 6, 2020 · 58 shares · 6,872 followers View post →
Cardiology
@PracUpCardio · X

Low-Dose Edoxaban in Very Elderly Patients With Atrial Fibrillation https://t.co/DI0s1k0vij #cardiology

Oct 4, 2020 · 880 followers View post →
OlgaDunaeva
@DunyaOlga · X

RT @Derek_Leong_RPh: ELDERCARE-AF: In Pts >80 y.o. with non-valvular AF, CHADS2 >1, unable to take OAC at approved doses, edoxaban 15 mg/d…

Oct 3, 2020 · 3 shares · 193 followers View post →
Dr. bycomet
@bycomet · X

“Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation - PubMed” https://t.co/hnykOLe3lS

Oct 1, 2020 · 1 like · 7,947 followers View post →
Gord Fogg
@GordFogg · X

RT @Derek_Leong_RPh: ELDERCARE-AF: In Pts >80 y.o. with non-valvular AF, CHADS2 >1, unable to take OAC at approved doses, edoxaban 15 mg/d…

Sep 25, 2020 · 3 shares · 1,061 followers View post →
Devon McDonald
@McDevonMD · X

RT @Derek_Leong_RPh: ELDERCARE-AF: In Pts >80 y.o. with non-valvular AF, CHADS2 >1, unable to take OAC at approved doses, edoxaban 15 mg/d…

Sep 25, 2020 · 3 shares · 2,744 followers View post →
Derek Leong
@Derek_Leong_RPh · X

ELDERCARE-AF: In Pts >80 y.o. with non-valvular AF, CHADS2 >1, unable to take OAC at approved doses, edoxaban 15 mg/d ⬇️stroke/systemic embolism vs. placebo (ARR 4.4%/year). ⬆️Bleeding with edoxaban, esp. GI bleed (ARI 1.5%/year), CRNMB (ARI 5.6%/year). https://t.co/jpxIcayR6t https://t.co/QvuV3hOnjb

Sep 24, 2020 · 15 likes · 3 shares · 1,560 followers View post →
Michael Buratovich
@MichaelBuratovi · X

Low-Dose Edoxaban in Very Elderly Patients With Atrial Fibrillation | comment: Peter Lin MD, CCFP https://t.co/IdzlpZn4sR via @practiceupdate

Sep 24, 2020 · 1,168 followers View post →
Oncology
@PracUpOnc · X

Low-Dose Edoxaban in Very Elderly Patients With Atrial Fibrillation https://t.co/GTEZh9nPvF #hematology

Sep 23, 2020 · 1,329 followers View post →
koureiigaku
@koureiigaku · X

結論として、標準量の経口抗凝固薬が適応外の日本の超高齢非弁膜症性心房細動患者に対するエドキサバン15mg/日投与は、偽薬よりも脳卒中もしくは全身性塞栓症の予防効果に優れ大出血を増やしませんでした。 https://t.co/soriuCqKqe

Sep 21, 2020 · 2 likes · 849 followers View post →
Euri Rivas
@euri_rivas · X

RT @mencardio: Low-Dose Edoxaban in Very Elderly Patients With Atrial Fibrillation | comment: Peter Lin MD, CCFP https://t.co/Mx5y1drrhv vi…

Sep 20, 2020 · 1 share · 48 followers View post →
Ivan Mendoza
@mencardio · X

Low-Dose Edoxaban in Very Elderly Patients With Atrial Fibrillation | comment: Peter Lin MD, CCFP https://t.co/Mx5y1drrhv via @practiceupdate

Sep 18, 2020 · 2 likes · 1 share · 7,254 followers View post →
kawasakigim@川崎市立川崎病院総合内科
@kawasakigim · X

総合内科は毎日のアップデートを欠かしません!今日は研修医の先生とELDERCARE-AF試験を読みました。日本発の質の高いRCTです。https://t.co/TILPqOxvFX

Sep 18, 2020 · 2 likes · 72 followers View post →
onioni
@ONIONI_abc · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation https://t.co/N6YmKbdYCv

Sep 17, 2020 · 654 followers View post →
Eslam Abdellah
@EslamAbdellah8 · X

RT @ChaturvediNeuro: Getting clinicians to anticoagulate elderly patients with A FIB is challenging, esp. with previous falls/GI bleeds. EL…

Sep 14, 2020 · 25 shares · 47 followers View post →
のんびり
@ONQlrhPIX79SPoj · X

https://t.co/9Jx6AYiYJv

Sep 11, 2020 · 172 followers View post →
yuhei
@yxip01 · X

RT @koureiigaku: 80歳以上の超高齢心房細動者に対する低用量のエドキサバンの有効性と安全性を評価したELDERCARE-AF試験の論文がNEJMに掲載されていたので抄訳します。 結果、エドキサバン15mg/日投与は偽薬より脳卒中や全身性塞栓症が少なく、大出血の発…

Sep 11, 2020 · 4 shares · 7 followers View post →
令和姥捨山病院窓際内科
@setrq9HfAVRwdju · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/83dI9Qs0ce

Sep 11, 2020 · 779 followers View post →
岩手医科大学 脳神経内科・老年科
@IwateNeurol · X

RT @koureiigaku: 80歳以上の超高齢心房細動者に対する低用量のエドキサバンの有効性と安全性を評価したELDERCARE-AF試験の論文がNEJMに掲載されていたので抄訳します。 結果、エドキサバン15mg/日投与は偽薬より脳卒中や全身性塞栓症が少なく、大出血の発…

Sep 10, 2020 · 4 shares · 1,024 followers View post →
แมว(ไม่ว่างแล้ว)ในจักรวาล
@RaviponSH · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/anGYl2Qiho

Sep 10, 2020 · 204 followers View post →
koureiigaku
@koureiigaku · X

80歳以上の超高齢心房細動者に対する低用量のエドキサバンの有効性と安全性を評価したELDERCARE-AF試験の論文がNEJMに掲載されていたので抄訳します。 結果、エドキサバン15mg/日投与は偽薬より脳卒中や全身性塞栓症が少なく、大出血の発生も多くはありませんでした。 https://t.co/ERRfkQifDt

Sep 10, 2020 · 10 likes · 4 shares · 849 followers View post →
Denis A
@Merckxcycling · X

RT @bryanacotton1: Lemme fix conclusion by showing results...”rate of major bleeding was 3.3% in edoxaban group, 1.8% in placebo (P=0.09)..…

Sep 10, 2020 · 3 shares · 1,893 followers View post →
Behnood Bikdeli
@bbikdeli · X

RT @juanjolopezn: In very elderly patients with nonvalvular #AF who were not appropriate candidates for standard doses of oral anticoagulan…

Sep 9, 2020 · 2 shares · 1,251 followers View post →
Mayra Hawkins
@mayrahawkinssh · X

RT @juanjolopezn: In very elderly patients with nonvalvular #AF who were not appropriate candidates for standard doses of oral anticoagulan…

Sep 9, 2020 · 2 shares · 158 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

RT @syuichiao89: [文献]心房細動を有する超高齢者に低用量エドキサバンで脳卒中及び全身性塞栓症が少ないかもしれない(RCT DOI: 10.1056/NEJMoa2012883) : 薬剤師の地域医療日誌 https://t.co/A5qFXEkb21

Sep 8, 2020 · 2 shares · 8,604 followers View post →
Hilario Badiola
@hilariobad59 · X

RT @jsenior64: #ESCCongress #ESCCongress2020 @escardio siguió con el ELDERCARE AF, edoxaban en pacientes > 80 años con FA con resultados po…

Sep 8, 2020 · 3 shares · 189 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

[文献]心房細動を有する超高齢者に低用量エドキサバンで脳卒中及び全身性塞栓症が少ないかもしれない(RCT DOI: 10.1056/NEJMoa2012883) : 薬剤師の地域医療日誌 https://t.co/A5qFXEkb21

Sep 7, 2020 · 10 likes · 2 shares · 8,604 followers View post →
Ana Blanco Hidalgo
@anablancoha · X

RT @jsenior64: #ESCCongress #ESCCongress2020 @escardio siguió con el ELDERCARE AF, edoxaban en pacientes > 80 años con FA con resultados po…

Sep 7, 2020 · 3 shares · 1,494 followers View post →
Tobenna Iyidobi
@Tobennaiyidobi · X

RT @NEJM: Original Article: Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation #ESCCongress

Sep 7, 2020 · 58 shares · 190 followers View post →
EB Sladek
@eb_sladek · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/DmIb1ukl4z

Sep 6, 2020 · 3 likes · 111 followers View post →
はぎ
@hagi220 · X

RT @pinacol: 【RCT】脳卒中予防に承認された投与量での経口抗凝固薬治療が適切でないと考えられる高齢(≥80歳)の心房細動患者へのエドキサバン15mg/dayの投与は、プラセボと比較して、脳卒中/全身性塞栓症の年率を減少させ、大出血の年率に差はなかった(消化管出血は…

Sep 5, 2020 · 1 share · 493 followers View post →
pinacol
@pinacol · X

【RCT】脳卒中予防に承認された投与量での経口抗凝固薬治療が適切でないと考えられる高齢(≥80歳)の心房細動患者へのエドキサバン15mg/dayの投与は、プラセボと比較して、脳卒中/全身性塞栓症の年率を減少させ、大出血の年率に差はなかった(消化管出血は多かった)。 #ペ読 https://t.co/PmA0d5beuI

Sep 5, 2020 · 6 likes · 1 share · 1,616 followers View post →
Gaurav Thakur
@GThakurBrainDO · X

RT @VivienHLee: ELDERARE-AF. In elderly Japanese pts with Afib not appropriate for standard AC, low-dose edoxaban (15mg QD) was superior to…

Sep 4, 2020 · 1 share · 103 followers View post →
ときヲ
@toki_wo_koe · X

周回遅れ。これ結果出てたんですね、エドキバン15mg。驚くような内容ではないが、有意差の付いていないmajor bleedingは症例数の問題だろう考察される。 Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/mtwHLyY32c

Sep 4, 2020 · 3 likes · 2,589 followers View post →
Vivien Lee MD FAAN
@VivienHLee · X

ELDERARE-AF. In elderly Japanese pts with Afib not appropriate for standard AC, low-dose edoxaban (15mg QD) was superior to placebo in preventing #stroke or systemic embolism. Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/qQ5xOVXbuN

Sep 4, 2020 · 5 likes · 1 share · 954 followers View post →
John Morley
@Meddocslu · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/rsXMhbWvEj

Sep 3, 2020 · 1,215 followers View post →
Professor Hanne Christensen
@HanneKChr · X

RT @NINDSdirector: More evidence that anticoagulants reduce #stroke in persons with Atrial Fibrillation; even those over 80 yrs old. Low-Do…

Sep 3, 2020 · 2 shares · 724 followers View post →
arun achuthan/dr/mr
@arun4513 · X

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation | NEJM https://t.co/uSSxDCazSr

Sep 3, 2020 · 401 followers View post →