The overall tone reflects a strong focus on the complex biological processes involved in T2DM, with examples like mentions of insulin resistance, beta cell decline, and genetic factors. Words like 'compelling,' 'critical,' and references to specific research highlight both engagement and recognition of the article’s significance in advancing understanding of the disease.
AgreementModerate agreement
Most discussions support the article's emphasis on the complex mechanisms underlying T2DM, recognizing its role in explaining disease progression.
InterestHigh interest
Posts demonstrate high interest by addressing multifaceted aspects such as genetic factors, lipotoxicity, and cellular dysfunction.
EngagementModerate engagement
There is moderate engagement with users referencing specific components like pancreatic beta-cell decline, insulin resistance, and metabolic alterations, indicating they are actively contemplating the material.
ImpactModerate impact
The discussions suggest a recognition that understanding pathophysiology could influence future treatments and public health strategies, indicating a moderate impact.
Abstract in brief
T2DM is a metabolic disorder caused by defective insulin secretion and the inability of insulin-sensitive tissues to respond properly to insulin, leading to problems in glucose regulation.
The review focuses on the molecular mechanisms involved in insulin production, release, sensing, and their impact on organs, as well as factors like nutrition, physical activity, gut health, and metabolic memory that contribute to disease progression.
It also examines the connection between T2DM, insulin resistance, and the increased risk of atherosclerosis and cardiovascular complications.]
Shiv Kumar, Ph.D. student (Supervisor: Dr. Yogendra S. Padwad) will defend thesis entitled “Mechanistic role of phloretin and phloridzin in the pathophysiology of type-2 diabetes mellitus and colon inflammation” on March 16, 2020 at @CSIR_IND-@CSIR_IHBT, Palampur. @ProfSangwan
Mar 16, 2020 · 9 likes · 1 share · 12,641 followersView post →
KE
Ketogenic European
@Ketogenic_EU · X
Oh look, exactly what @ChrisPalmerMD argues for mental health... Mitochondrial damage and dysfunction... who knew
https://t.co/iMq1cXt7hE https://t.co/IAFTu9NQuK
Dec 17, 2022 · 4 likes · 1 share · 1,025 followersView post →
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ᴍᴏɴᴋ ᴀᴇsᴛʜᴇᴛɪᴄ
@monkaesthetic · X
Tip 2 diyabet, nihayetinde pankreasın insülini dışarı atma yeteneğindeki veya hücrelerin kan şekerini alma kabiliyetindeki işlev bozukluğu yoluyla gelişir.
https://t.co/aMSHNjFt01
Hem tek başına hem de birlikte kan şekeri düzeylerinin yükselmesine neden olabilir.
Aug 18, 2023 · 3 likes · 2,993 followersView post →
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ChefKarim02
@ChefKarim02 · X
@NutritionistKD What is the pathophysiology of type 2 diabetes mellitus
What are the signs and symptoms of type 2 diabetes mellitus.
What are the ADA diagnostic criteria for type 2 diabetes mellitus.
When should asymptomatic adults be screened for type 2 diabetes mellitus .
Nov 12, 2024 · 1 like · 1,924 followersView post →
TD
thirsty diabetic
@thediabeticorg · X
@bridgetp1019 @howitworked @WhiteHouse I read it and you should read this:
https://t.co/ggwW4poaWa
Not all type 2 diabetics are fat and lazy and infact insulin resistance is almost certainly a genetic mutation
Diabetes mellitus type 2 develops due to disrupted insulin production and resistance. This video explores mechanisms behind beta cell dysfunction, insulin response impairment, and how high-energy intake affects…
This video explains how environmental and lifestyle factors such as poor diet, inactivity, and stress contribute to type 2 diabetes. It emphasizes the importance of healthy habits and prevention strategies to reduce…
Spatial bayesian modeling of diabetes mellitus (DM) risk in the United States | BMC Public Health
https://www.newsbeep.com/au/301393/
Galicia-garcia U, Benito-vicente A, Jebari S, Larrea-sebal A. Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci…
Spatial bayesian modeling of diabetes mellitus (DM) risk in the United States | BMC Public Health
https://www.newsbeep.com/ie/153670/
Galicia-garcia U, Benito-vicente A, Jebari S, Larrea-sebal A. Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci…
@agingdoc1 The concept of lipotoxicity presents a compelling framework for understanding the pathophysiology of Type 2 Diabetes Mellitus. By elucidating the role of excess lipids in cellular dysfunction, we can better strategize therapeutic interventions.
@NutritionistKD What is the pathophysiology of type 2 diabetes mellitus
What are the signs and symptoms of type 2 diabetes mellitus.
What are the ADA diagnostic criteria for type 2 diabetes mellitus.
When should asymptomatic adults be screened for type 2 diabetes mellitus .
Nov 12, 2024 · 1 like · 1,924 followersView post →
AA
Alliance For Diabetes (AFD)
@DIABETESCARE11 · X
Diminished beta cell mass is a critical part of the pathophysiology of type 2 diabetes mellitus
Tip 2 diyabet, nihayetinde pankreasın insülini dışarı atma yeteneğindeki veya hücrelerin kan şekerini alma kabiliyetindeki işlev bozukluğu yoluyla gelişir.
https://t.co/aMSHNjFt01
Hem tek başına hem de birlikte kan şekeri düzeylerinin yükselmesine neden olabilir.
Aug 18, 2023 · 3 likes · 2,993 followersView post →
TD
thirsty diabetic
@thediabeticorg · X
@bridgetp1019 @howitworked @WhiteHouse I read it and you should read this:
https://t.co/ggwW4poaWa
Not all type 2 diabetics are fat and lazy and infact insulin resistance is almost certainly a genetic mutation
@corbinsabol @BurnettWrites @WhiteHouse "The pandemic of type 2 diabetes mellitus (T2DM) has been largely attributed to the increasing prevalence of worldwide obesity at a geometric rate.
However, the number of non-obese patients with T2DM is also on the rise, and it is as high as 60-80% in https://t.co/ggwW4poaWa
Oh look, exactly what @ChrisPalmerMD argues for mental health... Mitochondrial damage and dysfunction... who knew
https://t.co/iMq1cXt7hE https://t.co/IAFTu9NQuK
Dec 17, 2022 · 4 likes · 1 share · 1,025 followersView post →
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Konrad
@Konrad06527208 · X
@jbart_xy @TymoteuszKochan …observed that 10-20% of individuals with T2DM are non-obese, after excluding latent autoimmune diabetes in adults (LADA) and other forms of diabetes. In some parts of the world…, the prevalence of the non-obese variant is as high as 60-80% https://t.co/76A5ZKV3XU.
What is the pathophysiology of type 2 diabetes?
The pathophysiology of type 2 diabetes mellitus is characterized by peripheral insulin resistance, impaired regulation of hepatic glucose production, and declining β-cell function, eventually leading toβ -cell failure.
CSIR-Institute of Himalayan Bioresource Technology
@CSIR_IHBT · X
RT @AcSIR_India: Shiv Kumar, Ph.D. student (Supervisor: Dr. Yogendra S. Padwad) will defend thesis entitled “Mechanistic role of phloretin…
Mar 16, 2020 · 1 share · 9,338 followersView post →
A
AcSIR
@AcSIR_India · X
Shiv Kumar, Ph.D. student (Supervisor: Dr. Yogendra S. Padwad) will defend thesis entitled “Mechanistic role of phloretin and phloridzin in the pathophysiology of type-2 diabetes mellitus and colon inflammation” on March 16, 2020 at @CSIR_IND-@CSIR_IHBT, Palampur. @ProfSangwan
Mar 16, 2020 · 9 likes · 1 share · 12,641 followersView post →
(2020). Pathophysiology of Type 2 Diabetes Mellitus. International journal of molecular sciences, 21(17), 6275. https://doi. org/10.3390/ijms21176275 · No ...
https://doi.org/10.3390/ijms21176275 *The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver ...
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