25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atherosclerosis" https://t.co/3O3XJrjVQo
Zero Coronary Artery Calcium Score: Desirable, but Enough?
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Sep 2020 – Mar 2025Where it's discussed
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What people are saying
Multiple discussions highlight the paradox of a zero CAC score, with commenters stating that 'about one-fourth to one-third of the total incident cardiovascular disease events occur in those with a CAC of zero.' This emphasizes a disconnect between a low score and actual heart disease risk, enhancing the urgency in words like 'oversimplified' and 'misunderstood,' which indicate a deeper comprehension and concern for cardiovascular health, ultimately framing the publication as a vital part of ongoing healthcare conversations.
Most discussions indicate a general consensus on the limitations of relying solely on a zero CAC score.
Contributors express significant curiosity about the implications of the findings.
Many comments provide detailed scrutiny of the article's arguments, discussing different aspects of coronary artery disease.
Participants believe the publication raises important points that could significantly influence clinical practice and patient awareness.
Abstract in brief
- A zero coronary artery calcium (CAC) score indicates a low risk of heart disease, suggesting minimal calcium buildup in the arteries.
- However, having a zero score doesn't completely rule out the possibility of heart issues, as other risk factors and conditions can still contribute to cardiovascular problems.
- It's important to consider a comprehensive approach to heart health, including lifestyle choices and regular check-ups, rather than solely relying on the CAC score.
Top posts
Most liked on X and Bluesky#Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.co/tA1jXwOmHs
@DoctorTro CAC is a late stage marker ... "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@rowforfun @scott_pysher @CarnivoreMD “Calcified plaque (detected as CAC on computed tomography imaging), however, represents a small proportion of the total plaque burden. Hence, there is a disconnection between zero calcium and zero atherosclerosis” https://t.co/B2Ra0lBjfM
@rowforfun @scott_pysher @CarnivoreMD “Overall, ≈70% to 90% of younger patients are expected to have a CAC of zero” - referring to below 55 years of age. https://t.co/B2Ra0lBjfM
@CapDefender I have not extensively researched. But this paper was sent to me as a resource. https://t.co/vc5fgQ4B1l
All mentions
Debunking 5 Myths About the Coronary Calcium Score in Heart Disease Risk
Understanding Coronary Artery Calcium Scores and Heart Health
A zero coronary artery calcium (CAC) score indicates a low risk of heart disease, suggesting minimal calcium buildup in the arteries. However, it doesn't eliminate the possibility of cardiovascular issues. It's…
@DudzLightLime Curious - how does this square with the below thanks? "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero" https://t.co/IoZCkLxweF
@CarnivoreFriend "Calcified plaque (detected as CAC on computed tomography imaging), however,
@CarnivoreFriend CAC is a late stage marker and also doesn't pick up the more dangerous soft plaque "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero" https://t.co/IoZCkLxweF
@CarnivoreFriend This article talks about some of the issues. There are a number articles out there talking about the zero calcium paradox and still getting significant CAD. Prob age < 50 and women need to play close attention. A zero CACS may not be very helpful. https://t.co/xIEuo3O7XW
@CaryKelly11 "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero " "Calcified plaque ... however, represents a small proportion of the total plaque burden" https://t.co/IoZCkLxweF
@SBakerMD "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero" "Calcified plaque ... represents a small proportion of the total plaque burden" https://t.co/IoZCkLxweF
@CaryKelly11 "Calcified plaque (detected as CAC on computed tomography imaging), however, represents a small proportion of the total plaque burden. Hence, there is a disconnection between zero calcium and zero atherosclerosis" https://t.co/IoZCkLxweF
@CaryKelly11 "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@CaryKelly11 CAC is a late stage marker so not particularly surprising given his recent change to a saturated fat heavy diet Also: "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero" https://t.co/IoZCkLxweF
@Paddy_Barrett How does this fit in to that thanks? "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@StevenMBelknap I sent you the link for that https://t.co/HLWVTpys2P CAC score is a marker of advanced disease state noted by calcified plaque, but the soft-plaque can just as well cause heart attacks, and it is not totally clear if calcified plaque is worse than soft plaque.
@StevenMBelknap Yes about 80% of CAC0 aren't old enough to have complicated lesions and resulting symptoms, and won't have heart attack in the near future. But 30% of heart attacks occur in CAC0. So ultimately what CAC is measuring is chances of resuscitation. https://t.co/rdit2lm2f6
RT @withered_haze: @cultistslayer @triagemethod Saying 0 CAC means you’re in the clear is like saying that you’re definitely a good driver…
@cultistslayer @triagemethod Saying 0 CAC means you’re in the clear is like saying that you’re definitely a good driver because you haven’t had a head-on collision. Plenty of people having ASCVD events with a CAC of 0: https://t.co/dCEzKIX2Ds
@Marion436842126 "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@Fynnderella1 "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@raphaels7 @MohammedAlo He’s referencing this (poorly, I might add) https://t.co/UQpoMEFiEM
@BiggestComeback @raphaels7 @MohammedAlo https://t.co/ItLB1cubEm).
@BiggestComeback @raphaels7 @MohammedAlo Chris, I found this AHA article that cites those statistics: https://t.co/yjOk1QaWQ1
RT @LLicit_Tweet: @DoctorTro CAC is a late stage marker ... "About one-fourth to one-third of the total incident cardiovascular disease (CV…
@DoctorTro CAC is a late stage marker ... "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@thoroughlyconf1 @MohammedAlo "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@profitnothealth @nutrition_facts @SBakerMD @KenDBerryMD "Calcified plaque (detected as CAC), however, represents a SMALL proportion of the total plaque burden. Hence, there is a disconnection between zero calcium and zero atherosclerosis ..." Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@khurramn1 @SABOURETCardio @MichaelJBlaha @rauldsf_santos "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@SBakerMD Quite deniable actually ... "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@tiras_corner "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
@CapDefender I have not extensively researched. But this paper was sent to me as a resource. https://t.co/vc5fgQ4B1l
@CarnivoreIs @bahrani_arman CAC is a late stage test. "about 1/3 of CVD events occur in those with a CAC of zero & another 1/3 occur in those with a CAC between 0 and 100 ..." ApoB / LDL blood test much more informative ... Zero Coronary Artery Calcium Score Desirable, but Enough? https://t.co/IoZCkLxweF
@SBakerMD CAC is a late stage test "about one-third of CVD events occur in those with a CAC of zero and another one-third occur in those with a CAC between 0 and 100 ..." Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@MsMiaMendez @SBakerMD @joerogan @realDaveFeldman @nicknorwitz As someone else mentioned, CAC is a late stage test "about one-third of CVD events occur in those with a CAC of zero and another one-third occur in those with a CAC between 0 and 100" Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@Hume312 @neeche41 @JeremySussman https://t.co/wmliRlwgQ1
@CaryKelly11 Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@BrianGurwitz in the case of that quote it includes CHD, stroke, heart failure, and peripheral artery disease from: https://t.co/qMix7AsilX
@GarethRowland20 @DaveWaltz5 CAC is a measure of older calcified plaque - doesn't pick up soft plaque which kills most Zero Coronary Artery Calcium Score Desirable, but Enough? 2020 https://t.co/IoZCkLxweF
@BudoffMd @khurramn1 @rblument1 @RonBlankstein "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero ..." https://t.co/IoZCkLxweF
Some people can't handle science: About one-fourth to one-third of the total incident cardiovascular disease events occur in those with a CAC of zero...https://t.co/D5odasQ2K5 https://t.co/Hrr7gKRzq9
@SBakerMD About one-fourth to one-third of the total incident cardiovascular disease events occur in those with a CAC of zero...https://t.co/D5odasQ2K5
@richcollins @towianisci @skydog576 @SBakerMD About one-fourth to one-third of the total incident cardiovascular disease events occur in those with a CAC of zero... https://t.co/D5odasQ2K5
RT @DavidLBrownMD: @neeche41 @SABOURETCardio 25-33% of events occur in individuals with CAC 0. https://t.co/ttJeh5jJMb
@neeche41 @SABOURETCardio 25-33% of events occur in individuals with CAC 0. https://t.co/ttJeh5jJMb
Zero Coronary Artery Calcium Score Desirable, but Enough? https://t.co/RBs5XBQKZZ
@SanghviMahaveer @chhuti_is You can refer this: https://t.co/Vm1hxD5tPi
@thoroughlyconf1 @ScepticalDoctor @skepcard I think you give too much weight in your diagnosis to the CAC. https://t.co/dgks4f0m6a
RT @JayhawkLipidDoc: @LilyMorrison823 @drscottyk @DrNadolsky Interesting. We are learning more and more about different phenotypes of lp(a)…
@LilyMorrison823 @drscottyk @DrNadolsky Interesting. We are learning more and more about different phenotypes of lp(a) and their contributions to CAD. Of note, CAC of 0 doesn’t mean no atherosclerosis or events. Much more work to be done here. Article link for an opinion: https://t.co/IbaHeuS6MN
@nutrition_long @The_Nutrivore @PragmaV https://t.co/TnH3RDnQ85 Here is where I told you before, and here's why you're demented. https://t.co/qQb4sV3PEJ
@J17888804 @Michele62829418 Don't forget that many with a CAC of 0 under the age of 40 still have Coronary Artery Disease. CAC only detects calcified plaque. "About one-fourth to one-third of the total incident cardiovascular disease (CVD) events occur in those with a CAC of zero" https://t.co/B2Ra0lBjfM
@DrPaulMason @scottmorgan88 The rest of the story w zero CAC https://t.co/VLUypBKfvB @LukeEdwards504 "A zero calcium score is desirable, but is it enough to defer therapy given that up to one-third of events will occur in this group?"
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @Plant_proof: @rowforfun @scott_pysher @CarnivoreMD “Overall, ≈70% to 90% of younger patients are expected to have a CAC of zero” - refe…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
RT @NutritionMadeS3: 25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atheroscl…
25-33% of CVD events occur in those with a CAC of zero "there is a disconnect between zero calcium and zero atherosclerosis" https://t.co/3O3XJrjVQo
CAC เนี่ยต่ำก็คือเสี่ยงต่ำ มันใช้พยากรณ์ความเสี่ยงได้ แต่ไม่ใช่ว่า 0 แล้วมึงลั้นลาได้ กินยังไงก็ได้ ทำตัวยังไงก็ได้ แค่ว่าความเสี่ยงมันต่ำกว่าค่าที่มากกว่าแค่นั้นเอง เนี่ยอันนี้ก็เห็นคนไทยจำนวนมากที่เข้าใจผิดกับไอ้ค่านี่อยู่เยอะเหมือนกัน https://t.co/NMRkZJ9A6D
@bohdyone not necessarily, some people have significant stenosis, and even events, with CAC=0 it has prognostic value and ofc having a 0 is better than having it higher, but it's a bit oversimplified and misunderstood https://t.co/rp3C37Ckzf https://t.co/HrzhSFZA5P
@PLooserMD @NutritionMadeS3 https://t.co/CredyvTenl
RT @Plant_proof: @rowforfun @scott_pysher @CarnivoreMD “Calcified plaque (detected as CAC on computed tomography imaging), however, represe…
RT @Plant_proof: @rowforfun @scott_pysher @CarnivoreMD “Calcified plaque (detected as CAC on computed tomography imaging), however, represe…
RT @Plant_proof: @rowforfun @scott_pysher @CarnivoreMD “Calcified plaque (detected as CAC on computed tomography imaging), however, represe…
@rowforfun @scott_pysher @CarnivoreMD “Overall, ≈70% to 90% of younger patients are expected to have a CAC of zero” - referring to below 55 years of age. https://t.co/B2Ra0lBjfM
@rowforfun @scott_pysher @CarnivoreMD “Calcified plaque (detected as CAC on computed tomography imaging), however, represents a small proportion of the total plaque burden. Hence, there is a disconnection between zero calcium and zero atherosclerosis” https://t.co/B2Ra0lBjfM
RT @CardioPublisher: Zero Coronary Artery Calcium Score: Desirable, but Enough? #CardioTwitter #MedTwitter #MedEd https://t.co/BbLDscNBZw
Zero Coronary Artery Calcium Score: Desirable, but Enough? #CardioTwitter #MedTwitter #MedEd https://t.co/BbLDscNBZw
RT @KoushikReddyMD: Zero Coronary Artery Calcium Score Desirable, but Enough? https://t.co/vVcsrlHjcs
Zero Coronary Artery Calcium Score Desirable, but Enough? https://t.co/vVcsrlHjcs
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
Zero Coronary Artery Calcium Score https://t.co/WErkzd89ju #kahnchronicle
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
Zero Coronary Artery Calcium Score https://t.co/nXzs28Js0N The lipid people respond - A zero CAC score does not imply that all is perfect as a p<.05 does not imply no association -it's all in our perspective
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
RT @CircAHA: #Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.c…
#Perspective: Zero Coronary Artery Calcium Score - Desirable, but Enough? #AHAJournals @CBallantyneMD @vijay_nambi https://t.co/tA1jXwOmHs