PubHawk
February 2022 PMID 32930058

Naltrexone a potential therapeutic candidate for COVID-19.

Abhinav Choubey, Budheswar Dehury, Sunil Kumar, Bikash Medhi, Prosenjit Mondal

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Mentions

78
Peak: 56 in Feb 2023
across 4 sources since Sep 2020

Extended reach

352,472
potential audience

Total likes

8,341

Video views

190,400

Mentions per month

Sep 2020 – Dec 2025

Where it's discussed

  • X / Twitter71 posts
  • Reddit3 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The overall tone emphasizes the scientific potential and cost-effectiveness of repurposed drugs like naltrexone, with many posts sharing research articles and advocating for increased awareness and funding; words like 'potential,' 'safe,' and 'cheap' underline optimism and urgency, while references to ongoing trials highlight active engagement and hope for impactful medical advances.

AgreementModerate agreement

Most discussions express support or curiosity regarding the potential of naltrexone as a treatment, highlighting its promise based on scientific reasoning.

InterestHigh interest

Posts frequently mention repurposed drugs, low-dose naltrexone, and COVID-19, indicating high curiosity and attention to the topic.

EngagementHigh engagement

Many posts include detailed explanations, references to research, and calls for further action, reflecting deep engagement.

ImpactModerate impact

The discussions suggest a belief that naltrexone could significantly influence COVID-19 treatment options, though mostly based on preliminary data.

Abstract in brief

  • Naltrexone, an FDA-approved opioid antagonist, shows potential as a treatment for COVID-19 because it can reduce inflammation and may interfere with the virus's ability to infect cells by disrupting the spike protein's interaction with ACE2.
  • The drug also inhibits ERK12 phosphorylation, which is linked to viral replication, thereby potentially decreasing the virus's ability to replicate and cause damage.
  • Since naltrexone has already been approved by the FDA, low-dose naltrexone (LDN) might be repurposed quickly for COVID-19 therapy without the need for extensive toxicity testing.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Jayne
@JLC603 · X

Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson70⁩ ⁦@IMWHorvitz⁩ https://t.co/c0fLOOpNMQ

Sep 20, 2020 · 32 likes · 10 shares · 378 followers View post →
Alisontomyradioooo
@arisonsned · X

A good discussion on LDN, especially on very low doses - 0.5mg Used in cancer Used for animals Very safe Minimal side effects https://t.co/fe1VRQSGx9

Feb 11, 2023 · 9 likes · 2,999 followers View post →
Biotech
@ej23ny · X

$CBLI & $CYTO Naltrexone (CYTO-205) a promising therapeutic candidate for #COVID19 Abstract @wsbmod @reddit $NVAX $MRNA $INO $HGEN $SRNE $INO $BB $BBBY $BYND $CCIV $CLOV $CRIS $GM $GME $GTE $HIMS $KOSS $MUX $NAKD $NOK $SNDL $TSLA $AAPL $CYDY $TMO $bcrx https://t.co/ABzkykiWTC https://t.co/Gys8cuTayu

Feb 1, 2021 · 3 likes · 2,922 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Naltrexone a potential therapeutic candidate for #COVID19 https://t.co/aRBGzkF3UZ hypothesis and mechanistic paper - not definitive! #vaccineinjuries #postvaxlonghaul

Mar 16, 2022 · 2 likes · 8,808 followers View post →
Maija Haavisto
@DiamonDie · X

To my knowledge, two separate groups are running trials of low dose naltrexone in #COVID19. This paper explains why LDN might be helpful. https://t.co/DKZQT1HlXH

Sep 17, 2020 · 1 like · 7,852 followers View post →
Slu Tectock
@SluTectock · X

@NFairclough @furrypinkchaos @POTUS @crushtheracists And on hospitals were subsidized death factories The ☠️ protocol was: - create & release coronavirus - denial of treatment - Remdesivir, ventilators & to tags - mandated deadly untested gene therapy I’ve sent scientists & data supporting my hypothesis https://t.co/OYBVADcrRP

Feb 19, 2023 · 1 like · 7,477 followers View post →

All mentions

Anne
@Lyall3Lyall · X

RT @JLC603: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson70⁩ ⁦@I…

Dec 30, 2025 · 10 shares · 2,246 followers View post →
Wisdom all knowing
@wisdom_knowing · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Nov 17, 2024 · 10 shares · 1,146 followers View post →
Nicole LeBlanc
@nleblanc12 · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

May 29, 2024 · 10 shares · 2,977 followers View post →
fromthesource.net
@FromThe_Source · X

Repurposed drugs are cheap https://t.co/taToGAqs2R

Mar 12, 2023 · 26 followers View post →
Monique Tran
@MoniqueTran04 · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Feb 22, 2023 · 10 shares · 927 followers View post →
Nicole
@Nicantoine19 · X

@BlueSlots So sorry, this is tragic and even worse, no support from the government and doctors who did this to you. Maybe try this. https://t.co/PTpcaoMsSQ

Feb 22, 2023 · 1 like · 5 followers View post →
Slu Tectock
@SluTectock · X

@NFairclough @furrypinkchaos @POTUS @crushtheracists And on hospitals were subsidized death factories The ☠️ protocol was: - create & release coronavirus - denial of treatment - Remdesivir, ventilators & to tags - mandated deadly untested gene therapy I’ve sent scientists & data supporting my hypothesis https://t.co/OYBVADcrRP

Feb 19, 2023 · 1 like · 7,477 followers View post →
Arnold Paalvast
@ArnoldPaalvast · X

RT @michellecheatle: Repurposed drugs are cheap https://t.co/Bb68durjGM via @YouTube

Feb 16, 2023 · 1 share · 275 followers View post →
Madam Butterfly.
@michellecheatle · X

Repurposed drugs are cheap https://t.co/Bb68durjGM via @YouTube

Feb 15, 2023 · 1 like · 1 share · 920 followers View post →
Trisstina Stone
@TrisstinaS · X

RT @itsMalma: Repurposed drugs are cheap https://t.co/8E9o6R3BgK via @YouTube

Feb 14, 2023 · 1 share · 4,176 followers View post →
Trisstina Stone
@TrisstinaS · X

Repurposed drugs are cheap https://t.co/8E9o6R3BgK via @YouTube

Feb 14, 2023 · 1 like · 1 share · 4,176 followers View post →
Theresa Bates
@BatesTheresa · X

The public need to watch more videos like this. Another great education video from Dr. Campbell & his wonderful guests. Repurposed drugs are cheap https://t.co/LB8ewt8IrE via @YouTube

Feb 14, 2023 · 1,961 followers View post →
Peter Weigl
@weigl_ · X

@LuisenstadtFoto Tut mir leid, das zu lesen. Vielleicht mögen Sie sich das Gespräch hier

Feb 13, 2023 · 1 like · 1,052 followers View post →
jane
@janiehere2 · X

Repurposed drugs are cheap https://t.co/m3zeKfZZw6 via @YouTube

Feb 13, 2023 · 2,144 followers View post →
Lisa Rile
@Lisalibby110 · X

@elonmusk PLEASE watch this... you could make all the difference! Repurposed drugs are cheap https://t.co/SqpBaTqIAr via @YouTube

Feb 12, 2023 · 255 followers View post →
Maximus Powers
@MarkGra50507647 · X

Repurposed drugs are cheap https://t.co/XcqjyYG1uc via @YouTube

Feb 12, 2023 · 898 followers View post →
Fact Seeker
@FactSeeker14 · X

Repurposed drugs are cheap https://t.co/PZsPRWJLW5 via @YouTube

Feb 11, 2023 · 99 followers View post →
Alisontomyradioooo
@arisonsned · X

A good discussion on LDN, especially on very low doses - 0.5mg Used in cancer Used for animals Very safe Minimal side effects https://t.co/fe1VRQSGx9

Feb 11, 2023 · 9 likes · 2,999 followers View post →
Vaudeville Funtimes
@cabaretdays · X

Drugs that we are not prescribed any more because the patent has expired

Feb 10, 2023 · 2,816 followers View post →
Troy Roach
@Canal1point5 · X

Israeli Doctor talks about #LDN (Low Dose Naltrexone) as a "safe" repurposed treatment for #LongCovid. "Tricks body to upregulate Opiod pathway & Reduces inflammation." Repurposed drugs are cheap https://t.co/ThyakXsnIq via @YouTube

Feb 10, 2023 · 1 like · 1,630 followers View post →
Dirk Christiaan de Rijke
@chris47fr · X

https://t.co/pg5Od44Yhv

Feb 10, 2023 · 56 followers View post →
uandrewk
@uandrewk · X

RT @uandrewk: Repurposed drugs are cheap https://t.co/byadeRz4WK via @YouTube

Feb 10, 2023 · 1 share · 130 followers View post →
uandrewk
@uandrewk · X

Repurposed drugs are cheap https://t.co/byadeRz4WK via @YouTube

Feb 10, 2023 · 1 like · 1 share · 130 followers View post →
Scott Campbell
@ScottCa85749680 · X

Repurposed drugs are cheap https://t.co/Qsu7JVpEIs via @YouTube

Feb 9, 2023 · 1 followers View post →
Leon Tarr
@lBudt29 · X

Repurposed drugs are cheap https://t.co/hOFAKGEGy1 via @YouTube

Feb 9, 2023 · 79 followers View post →
Jacuzzi Frog - In the Soup!
@Typ0negative · X

Repurposed drugs are cheap https://t.co/3PsY1p9ioU via @YouTube

Feb 9, 2023 · 2,767 followers View post →
Nelliejs50
@Nelliejs501 · X

RT @kwestie: Voor al degenen die lijden onder de vaak ernstige langdurige bijverschijnselen van covid-19 zouden kunnen overwegen hun arts…

Feb 9, 2023 · 2 shares · 4,962 followers View post →
Andy Thomas
@andythomas631 · X

Repurposed drugs are cheap therefore are not used very much. I think this is a scandal. https://t.co/5PduVUpUug

Feb 9, 2023 · 1,641 followers View post →
Jasmina
@HilaNanhekhan · X

RT @kwestie: Voor al degenen die lijden onder de vaak ernstige langdurige bijverschijnselen van covid-19 zouden kunnen overwegen hun arts…

Feb 9, 2023 · 2 shares · 647 followers View post →
Alison ✝️
@Alison09947467 · X

@angryhacademic Watched this earlier & thought you might find it interesting… https://t.co/8d2XeWS7Xr

Feb 9, 2023 · 152 followers View post →
lester townsend
@lester_townsend · X

Repurposed drugs are cheap https://t.co/vBMTUMXLSz via @YouTube

Feb 9, 2023 · 98 followers View post →
kwestie
@kwestie · X

Voor al degenen die lijden onder de vaak ernstige langdurige bijverschijnselen van covid-19 zouden kunnen overwegen hun arts te vragen kennis te nemen van hetgeen in bijgaande video besproken wordt in. https://t.co/meqSGEUyCN

Feb 9, 2023 · 2 shares · 1,066 followers View post →
Gaute Adler Nilsen
@GauteNilsen · X

Repurposed drugs are cheap and effective against long covid + + +..? https://t.co/WqpJ2pRevK via @YouTube

Feb 9, 2023 · 14,237 followers View post →
Molly Hadit
@Myheartsathome · X

Repurposed drugs are cheap https://t.co/J7McJRqj2Q via @YouTube

Feb 9, 2023 · 1,346 followers View post →
La Contessa
@Victori39328075 · X

https://t.co/hi7kyOolJT

Feb 9, 2023 · 783 followers View post →
Mihail Ørsted Bennis
@ThaXmo · X

In case you think the medical system isn't broken, you need to listen to THIS !!! https://t.co/Y2kI0DwCWv

Feb 9, 2023 · 54 followers View post →
Random Opinions
@ProcappersP · X

A must watch and a must follow channel Repurposed drugs are cheap https://t.co/ltJQ2DbWaQ via @YouTube

Feb 9, 2023 · 150 followers View post →
Corine
@FloatingIsland · X

Repurposed drugs are cheap https://t.co/IHaBbrJWTA via @YouTube

Feb 9, 2023 · 1 like · 434 followers View post →
Lori Morse
@Lmsavy60 · X

Repurposed drugs are cheap https://t.co/I6cxEzqaQx via @YouTube

Feb 9, 2023 · 443 followers View post →
El Teton
@e_teton · X

RT @newmind99: Uncle Dr John with Dr Cohen Repurposed drugs are cheap 27 min https://t.co/ObNgdAUBl3

Feb 9, 2023 · 1 share · 455 followers View post →
StClair ⚡ Asset
@newmind99 · X

Uncle Dr John with Dr Cohen Repurposed drugs are cheap 27 min https://t.co/ObNgdAUBl3

Feb 9, 2023 · 1 share · 924 followers View post →
Mike Small
@MikeSma39091654 · X

Could we see a GENUINE HONEST Philanthropist take up the challenge to fund this research ? An ORPHAN drug costing nuppence that could HELP MILLIONS, maybe BILLIONS (soon) Or STAMPED OUT by Pfizer? What do you think? @thecoastguy @Nigel_Farage https://t.co/8TSmxh9cVz

Feb 9, 2023 · 556 followers View post →
Tim Urban
@TheRealTimUrban · X

Hey @mcuban if these two are correct there’s a drug that @costplusdrugs could partner with to change millions of lives. https://t.co/h1jnhAGHlM

Feb 9, 2023 · 27,570 followers View post →
Canadian Woman
@Shedawand · X

Repurposed Drugs Are Cheap Dr. Cohen discuss Naltrexone with Dr. John Campbell. Naltrexone: a potential therapeutic candidate for COVID-19, multiple sclerosis, fibromyalgia, inflammatory bowel disease ⁦ https://t.co/Jk0v3OCgZZ

Feb 9, 2023 · 1 like · 867 followers View post →
Ed fridovich
@EFridovich · X

Repurposed drugs are cheap https://t.co/THHjwwni75 via @YouTube

Feb 9, 2023 · 69 followers View post →
noa
@noaappou · X

Repurposed drugs are cheap https://t.co/9vORGNwe6W @YouTubeより

Feb 9, 2023 · 180 followers View post →
Sulev Viikna
@SViikna · X

Repurposed drugs are cheap - YouTube https://t.co/C2enI1btGc

Feb 9, 2023 · 1,832 followers View post →
L. Wayne Mathison
@WayneMathison · X

Repurposed drugs are cheap https://t.co/g06BHPbCB0 via @YouTube

Feb 9, 2023 · 5,551 followers View post →
3rd Party Boomer
@No1CookieLady · X

Repurposed drugs are cheap https://t.co/locHDzGOwO via @YouTube

Feb 9, 2023 · 1,912 followers View post →
Vincent Everts
@vincente · X

Interesting! Repurposed drugs are cheap https://t.co/6TJG0bQkYD therefore are not used very much. I think this is a scandal. Repurposed drugs are common in medicine, aspirin, morphine, viagra and prednisolone for example. After drugs have been on th… https://t.co/3eGct7qqPK

Feb 9, 2023 · 17,103 followers View post →
Frances
@MabelHeinzle · X

Repurposed drugs are cheap https://t.co/ppe38QKFNI via @YouTube another informative interesting video - use of repurposed drugs @drdrew @Johnincarlisle

Feb 9, 2023 · 1,758 followers View post →
Peter Weigl
@weigl_ · X

Sehr interessantes Gespräch über das Potential von extrem niedrigdosiertem Naltrexone bei Autoimmunerkrankungen, Long COVID und anderem. „Repurposed drugs are cheap“ https://t.co/8849AGHMZ9 via @YouTube

Feb 9, 2023 · 1,052 followers View post →
Cris33
@33_Cris_33 · X

Repurposed drugs are cheap https://t.co/ju4oo4Cb1Y via @YouTube

Feb 9, 2023 · 339 followers View post →
txcaver
@txcaver1 · X

Repurposed drugs are cheap https://t.co/j6eUxkOYdF via @YouTube

Feb 9, 2023 · 204 followers View post →
BallPoint
@twitaff · X

#repurposeddrugs #Adverseeffects #PfizerExposed #clinicaltrials https://t.co/FccU6UsmE8

Feb 9, 2023 · 1,058 followers View post →
taxineil3
@taxineil3 · X

Repurposed drugs are cheap https://t.co/HU1fUE3sxm via @YouTube

Feb 9, 2023 · 388 followers View post →
Isatou Sarr
@IsatouSarr4 · X

https://t.co/oUX6nz3lhc

Feb 9, 2023 · 1 like · 46 followers View post →
Series Tout Azimut
@seriephagous · X

Repurposed drugs are cheap https://t.co/Lf4mOHgSJn via @YouTube

Feb 9, 2023 · 649 followers View post →
Jesus Castro, Ph.D.
@JCastro_Marrero · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Jul 10, 2022 · 10 shares · 995 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Naltrexone a potential therapeutic candidate for #COVID19 https://t.co/aRBGzkF3UZ hypothesis and mechanistic paper - not definitive! #vaccineinjuries #postvaxlonghaul

Mar 16, 2022 · 2 likes · 8,808 followers View post →
Campbell Neurosciences
@CampbellNeuros1 · X

@LDNNow interesting paper showing anti inflammatory activity of low dose naltrexone may be useful in #COVID19 https://t.co/UvbJouD6QE

Jun 12, 2021 · 2,115 followers View post →
Biotech
@ej23ny · X

$CBLI & $CYTO Naltrexone (CYTO-205) a promising therapeutic candidate for #COVID19 Abstract @wsbmod @reddit $NVAX $MRNA $INO $HGEN $SRNE $INO $BB $BBBY $BYND $CCIV $CLOV $CRIS $GM $GME $GTE $HIMS $KOSS $MUX $NAKD $NOK $SNDL $TSLA $AAPL $CYDY $TMO $bcrx https://t.co/ABzkykiWTC https://t.co/Gys8cuTayu

Feb 1, 2021 · 3 likes · 2,922 followers View post →
RenataBiss
@Renata86285002 · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Dec 22, 2020 · 10 shares · 2,557 followers View post →
hugo kitchen
@hugokitchen · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Oct 27, 2020 · 10 shares · 676 followers View post →
Tina
@Tina40957154 · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Sep 21, 2020 · 10 shares · 59 followers View post →
JerseyMe
@JerseylbiMe · X

RT @IMWHorvitz: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #MedTwitter and biochem rootcause peeps. What do ya…

Sep 20, 2020 · 1 share · 675 followers View post →
wemustrise
@wemustresist24 · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Sep 20, 2020 · 10 shares · 856 followers View post →
Low Dose Naltrexone
@LDNNow · X

RT @JayneLCrocker: Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson…

Sep 20, 2020 · 10 shares · 1,498 followers View post →
Jayne
@JLC603 · X

Full article: Naltrexone a potential therapeutic candidate for COVID-19 #LDN #COVID19 #NALTREXONE ⁦@LDNNow⁩ ⁦@bobthomson70⁩ ⁦@IMWHorvitz⁩ https://t.co/c0fLOOpNMQ

Sep 20, 2020 · 32 likes · 10 shares · 378 followers View post →
Maija Haavisto
@DiamonDie · X

To my knowledge, two separate groups are running trials of low dose naltrexone in #COVID19. This paper explains why LDN might be helpful. https://t.co/DKZQT1HlXH

Sep 17, 2020 · 1 like · 7,852 followers View post →
Adipose Papers
@adipose_papers · X

Naltrexone a potential therapeutic candidate for COVID-19. https://t.co/JfSUgcA1cI https://t.co/u9zaKkoJQL

Sep 16, 2020 · 2,488 followers View post →
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