Nature October 2020 PMID 32939091

Deep posteromedial cortical rhythm in dissociation.

Sam Vesuna, Isaac V Kauvar, Ethan Richman, Felicity Gore, Tomiko Oskotsky, Clara Sava-Segal, Liqun Luo, Robert C Malenka, Jaimie M Henderson, Paul Nuyujukian, Josef Parvizi, Karl Deisseroth

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150

Peak: 47 in Sep 2020

across 7 sources since Sep 2020

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AI synopsis

What people are saying

Numerous discussions mention terms like 'fascinating' and 'amazing work,' indicating enthusiasm for the research's findings about neuronal circuits related to dissociation. For example, one user called it a 'game changer,' while others mentioned its relevance for trauma and psychiatric illnesses, demonstrating how phrases and tone contribute to the overall positive sentiment and engagement with the article.

AgreementModerate agreement

The majority of discussions express support for the findings presented in the publication.

InterestHigh interest

Many users exhibit high levels of curiosity and highlight the relevance of the topic.

EngagementModerate engagement

Discussions include direct references to research methods and their implications for understanding dissociation.

ImpactHigh impact

Participants perceive the publication as having significant implications for fields such as psychiatry and neuroscience.

Abstract in brief

Advanced imaging methods enable cell-type-specific tracking of brain activity, helping to understand how complex behaviors arise.
Dissociation, an altered state of experience linked to trauma and certain drugs, has unknown neurophysiological underpinnings despite its importance.
In this study, researchers induced a dissociation-like state in mice using ketamine or phencyclidine, revealing rhythmic neural activity in specific brain regions and demonstrating the causal role of certain neurons in producing dissociative behaviors.

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All mentions

Understanding Ketamine's Role in Inducing Dissociation Effects

Ketamine is an anesthetic drug that produces a unique set of psychotropic effects known as dissociation. This video explores the neurophysiological underpinnings of dissociation, highlighting recent research that tracks…

Neuropharmacist · Mar 28, 2021 9,984 views

Neuroscience of Dissociation: Investigating Brain Activity

This video explores scientific findings on dissociation, including insights from advanced imaging methods that track brain activity. The research highlights how certain neurons may play a role in dissociative behaviors…

Hasan Iessa · Sep 2, 2025 6,914 views

Brad Caldwell

@Caldwbr · X

@ldallap1 Deisseroth study: Vesuna, Sam, et al. "Deep Posteromedial Cortical Rhythm in Dissociation." Nature, U.S. National Library of Medicine, Oct. 2020, https://t.co/BWO1PFGaOB. MIT study: https://t.co/74WjNAmKfS

Oct 18, 2024 · 1 like · 1,921 followers View post →

Jibran Khokhar

@DrJKhokhar · X

RT @Caldwbr: Replication of phenomenology of global burst-mode. Neural firing of RSP sub-video is taken from this paper: Deep posteromedia…

Apr 19, 2024 · 2 shares · 10,833 followers View post →

Earl K. Miller

@MillerLabMIT · X

RT @Caldwbr: Replication of phenomenology of global burst-mode. Neural firing of RSP sub-video is taken from this paper: Deep posteromedia…

Apr 19, 2024 · 2 shares · 41,525 followers View post →

عيادة د.خالد النفسية-Dr.Khalid Mental H. Clinic

@Drkhalidh1 · X

المصادر : 1-Sadock BJ, Sadock VA, Ruiz P, eds. Kaplan & Sadock’s Comprehensive Textbook of Psychiatry. Tenth edition. Wolters Kluwer; 2017. 2-Vesuna S, Kauvar IV, Richman E, et al. Deep posteromedial cortical rhythm in dissociation. Nature. 2020;586(7827):87-94.

Apr 15, 2024 · 3,701 followers View post →

Brad Caldwell

@Caldwbr · X

Apr 13, 2024 · 9 likes · 2 shares · 1,921 followers View post →

Rina Saltman

@rinatie_ceo · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/GfJPGYwbXq

Apr 5, 2024 · 3,560 followers View post →

Brad Caldwell

@Caldwbr · X

Papers cited in poster (worth reading): Deep posteromedial cortical rhythm in dissociation https://t.co/vb1KtYygNm Churchland RNNs https://t.co/YG82G9FXJf Attention feeds thru higher thalamus https://t.co/uVGpl69Ud4

Mar 27, 2024 · 1,921 followers View post →

Kazuya Horibe (@kazh289.bsky.social

@khoribe3 · X

Deep posteromedial cortical rhythm in dissociation https://t.co/13K0dBBEYJ

Feb 10, 2024 · 671 followers View post →

Daniela Duarte Domingues

@neurodaniela.bsky.social · Bluesky

7/7 "

Jan 18, 2024 View post →

Daniela Duarte Domingues

@neurodaniela.bsky.social · Bluesky

Jan 18, 2024 · 1 share View post →

Daniela Domingues

@neurodaniela · X

Today at the #psychedelic journal club, (in 1 hour) @hummuscience will lead the discussion of the paper "Deep posteromedial cortical rhythm in dissociation" @SamVesuna @KarlDeisseroth https://t.co/croOj0HAgV

Jan 17, 2024 · 4 likes · 958 followers View post →

Daniela Duarte Domingues

@neurodaniela.bsky.social · Bluesky

Jan 17, 2024 · 1 share View post →

Brad Caldwell

@Caldwbr · X

What else is neat is that retrosplenial cortex has been elsewhere identified to be the originator of these slowed waves upon hyperpolarization (NMDA-antagonism) via HCN1 channels- Vesuna, Sam, et al. "Deep Posteromedial Cortical Rhythm in Dissociation Nature, U.S. National

Sep 29, 2023 · 1,921 followers View post →

Jose Gallucci

@josegallucci · X

@Mazzoni_Marco https://t.co/Gost8DKg2G

Jun 1, 2023 · 1 like · 13,265 followers View post →

FND Portal - is no longer on X

@FndPortal · X

RT @josegallucci:

Jun 21, 2022 · 1 share · 6,937 followers View post →

Jose Gallucci

@josegallucci · X

Jun 21, 2022 · 6 likes · 1 share · 13,265 followers View post →

Adam Safron

@adamsafron · X

Will read. (Do the retrosplenial cortex findings for ketamine have convergent support for/by this work? https://t.co/oFYcApCBq6) https://t.co/TtWU02Uj3L

Mar 21, 2022 · 2,308 followers View post →

Andrew D. Huberman, Ph.D.

@hubermanlab · X

@openplains12 Mechanism of ketamine-driven dissociation (or a start at one anyway). https://t.co/WptzIoZsqr

Nov 15, 2021 · 6 likes · 1,655,179 followers View post →

Julien Burcher

@Dowellenough · X

RT @leafs_s: Nature Deep posteromedial cortical rhythm in dissociation https://t.co/aayrnblz3X

Jul 12, 2021 · 2 shares · 1,851 followers View post →

CLaE

@leafs_s · X

Nature Deep posteromedial cortical rhythm in dissociation https://t.co/aayrnblz3X

Jul 11, 2021 · 9 likes · 2 shares · 28,250 followers View post →

Matthew Markert MD PhD

@MatthewMarkert · X

@TheUncommonist @hubermanlab @KarlDeisseroth Read this one first to start understanding a new theory of the mind https://t.co/3sYJMLS2i8 Correlate example in human (with deep electrode interface) coming out VERY soon

Jul 7, 2021 · 848 followers View post →

CLaE

@leafs_s · X

Nature (2020) Deep posteromedial cortical rhythm in dissociation https://t.co/xMzZBdETwc

Feb 21, 2021 · 3 likes · 28,250 followers View post →

CLaE

@leafs_s · X

Nature Deep posteromedial cortical rhythm in dissociation https://t.co/xMzZBdWunK

Nov 27, 2020 · 2 likes · 28,250 followers View post →

Ani Wodeyar

@A_Wodeyar · X

Deep posteromedial cortical rhythm in dissociation https://t.co/caYm0vxten

Nov 18, 2020 · 498 followers View post →

Michel Blanc

@Blanc07Michel · X

RT @neurodelia: Deep posteromedial cortical rhythm in dissociation https://t.co/Yr5L6cjRNe

Oct 23, 2020 · 1 share · 1,667 followers View post →

Amsterdam Psychedelic Research Association (APRA)

@APRAresearch · X

Journal Club #15 – R. Faust (PhD): “Deep posteromedial cortical rhythm in dissociation” https://t.co/ZqzynDuXUL

Oct 12, 2020 · 4,007 followers View post →

Psychiatry_AUBMC

@AubmcPsychiatry · X

Deep posteromedial cortical rhythm in dissociation | Nature #psychtwitter #meded https://t.co/93B8aFAiGW

Sep 27, 2020 · 2 likes · 2,130 followers View post →

Chris Timmermann

@neurodelia · X

Deep posteromedial cortical rhythm in dissociation https://t.co/Yr5L6cjRNe

Sep 24, 2020 · 1 like · 1 share · 11,831 followers View post →

D. Chloe Chung, PhD

@dchloechung · X

Original @nature paper "Deep posteromedial cortical rhythm in dissociation" co-led by @SamVesuna @ikauvar from @KarlDeisseroth group: https://t.co/qfQT6OVgfu

Sep 23, 2020 · 1,419 followers View post →

千葉泰博

@yasuhirochiba · X

RT @inamura_do: ¶ 明日公開の『ネイチャー』に掲載されるであろう論文「解離における深部後頭葉皮質リズム」（Deep posteromedial cortical rhythm in dissociation）の解説記事「現実から切り離す脳のリズム（The bra…

Sep 23, 2020 · 1 share · 631 followers View post →

inamura fumiya

@inamura_do · X

¶ 明日公開の『ネイチャー』に掲載されるであろう論文「解離における深部後頭葉皮質リズム」（Deep posteromedial cortical rhythm in dissociation）の解説記事「現実から切り離す脳のリズム（The brain rhythms that detach us from reality）を読んでみる。 https://t.co/PYJFcns2lm

Sep 23, 2020 · 2 likes · 1 share · 286 followers View post →

Rina Saltman

@rinatie_ceo · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/GfJPGYe2Ji

Sep 23, 2020 · 3,560 followers View post →

PubMed Trending

@PubTrend · X

Trending on PubMed: Deep posteromedial cortical rhythm in dissociation. https://t.co/mQc2Xw49nL

Sep 22, 2020 · 5,168 followers View post →

Corina What?

@Corina_What · X

RT @heather_berlin: A Mind-Bending Rhythm In The Brain Can Act Like #Ketamine. Great work in @nature by @KarlDeisseroth et al. @Stanford @S…

Sep 19, 2020 · 2 shares · 7 followers View post →

saksham

@saksham_ngc4676 · X

RT @heather_berlin: A Mind-Bending Rhythm In The Brain Can Act Like #Ketamine. Great work in @nature by @KarlDeisseroth et al. @Stanford @S…

Sep 19, 2020 · 2 shares · 2 followers View post →

CLaE

@leafs_s · X

Nature Deep posteromedial cortical rhythm in dissociation https://t.co/xMzZBdETwc

Sep 18, 2020 · 4 likes · 28,250 followers View post →

KC-Brian

@Braingresser · X

RT @smiller360: Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/nUWChzqCav

Sep 18, 2020 · 1 share · 837 followers View post →

Steve Miller, PhD

@smiller360 · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/nUWChzqCav

Sep 18, 2020 · 1 like · 1 share · 4,759 followers View post →

Emmanuel A Stamatakis

@estamatakis · X

Fascinating! Deep posteromedial cortical rhythm in dissociation https://t.co/RZMXyHDw1R

Sep 18, 2020 · 811 followers View post →

Alen Juginović, M.D.

@AlenJuginovic · X

New #wireless & #wearable intracranial #EEG #device allows measuring and modulating #brain activity in freely moving humans. From @UCLA in @NeuroCellPress. Article: https://t.co/AUrmhT1Tt3 #medicine #science #research #innovation #technology #brain #neurology #HealthTech https://t.co/D1NG1tZbJL

Sep 18, 2020 · 3 likes · 406 followers View post →

Alen Juginović, M.D.

@AlenJuginovic · X

RT @hotsciballoon: Nutshell #106: #Dissociation, i.e. "out of body" experience, is caused by a specific #neuron activity pattern in the #hu…

Sep 18, 2020 · 1 share · 406 followers View post →

Hot Science Balloon

@hotsciballoon · X

Nutshell #106: #Dissociation, i.e. "out of body" experience, is caused by a specific #neuron activity pattern in the #human deep posteromedial #cortex & in mouse's #brain when given #anesthetic #ketamine. From @Stanford in @nature. Article: https://t.co/32stq9gBrR #research https://t.co/jlPwLdu09S

Sep 18, 2020 · 1 like · 1 share · 99 followers View post →

Sarael Alcauter

@AlcauterSarael · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 18, 2020 · 16 shares · 239 followers View post →

Grace Lim, MD MS

@LimGrapes · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/KVBJSczIIq

Sep 17, 2020 · 1,798 followers View post →

Emma Pettengale

@EmmaPettengale · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 1,327 followers View post →

o8t Labs

@o8tLabs · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 228 followers View post →

Avi Adhikari

@Avi_UCLA · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 1,140 followers View post →

CLaE

@leafs_s · X

Nature Deep posteromedial cortical rhythm in dissociation https://t.co/xMzZBdWunK

Sep 17, 2020 · 4 likes · 28,250 followers View post →

Stephan Krohn

@krohn_stephan · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 724 followers View post →

Giovanni Salum

@gsalumjr · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 539 followers View post →

koenv

@koen_vervaeke · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 1,046 followers View post →

Luke Norman

@Luke_J_Norman · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 754 followers View post →

Rick Summers, MD

@summersrpa · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 1,613 followers View post →

Paul Anastasiades

@P_Anastasiades · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 1,567 followers View post →

Kevin Mitchell

@WiringTheBrain · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 40,308 followers View post →

Jamie Hanson (@jamielarsh.bsky.social)

@JamieLarsH · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 9,673 followers View post →

Rajiv Radhakrishnan

@RajivR79 · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 835 followers View post →

HaiyangGeng

@HaiyangGeng · X

RT @sattertt: Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in…

Sep 17, 2020 · 16 shares · 261 followers View post →

Ted Satterthwaite

@sattertt · X

Amazing work from ⁦@KarlDeisseroth⁩ — highly relevant for trauma, BPD, and psychiatry. Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/R32Vws26Af

Sep 17, 2020 · 35 likes · 16 shares · 4,223 followers View post →

Rina Saltman

@rinatie_ceo · X

Deep posteromedial cortical rhythm in dissociation https://t.co/GfJPGYe2Ji

Sep 17, 2020 · 3,560 followers View post →

Jane Boissiere

@EdinPublishing · X

RT @dawso007: "results identify the molecular, cellular and physiological properties of a conserved deep posteromedial cortical rhythm that…

Sep 17, 2020 · 2 shares · 1,634 followers View post →

Marko Paşa

@markopaassa · X

RT @dawso007: "results identify the molecular, cellular and physiological properties of a conserved deep posteromedial cortical rhythm that…

Sep 17, 2020 · 2 shares · 156 followers View post →

crazyarchitect.13

@crazyarchitect · X

Deep posteromedial cortical rhythm in dissociation https://t.co/elUQcbXTci https://t.co/aZiPIPu4VL

Sep 17, 2020 · 165 followers View post →

Alejandro Higuera Matas

@ahmatas · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/k9LIEuGBR0

Sep 17, 2020 · 779 followers View post →

George Dawson

@dawso007 · X

"results identify the molecular, cellular and physiological properties of a conserved deep posteromedial cortical rhythm that underlies states of dissociation". Vesuna, S. et al. Deep posteromedial cortical rhythm in dissociation. Nature (2020). https://t.co/xnz8s04lpN

Sep 17, 2020 · 3 likes · 2 shares · 7,820 followers View post →

DTHSTR

@CDADeathStar · X

Deep posteromedial cortical rhythm in dissociation null https://t.co/1uulntHvvA #DTHSTR

Sep 16, 2020 · 113 followers View post →

Dr Krazy K

@DrBBKatta · X

Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/93STA9TfsZ

Sep 16, 2020 · 168 followers View post →

PurPurPurkinje

@tak_yamm · X

The brain rhythms that detach us from reality https://t.co/xUjiTg91G6 paper: Deep posteromedial cortical rhythm in dissociation https://t.co/eESmKgN4cf

Sep 16, 2020 · 1 like · 2,879 followers View post →

Isabella Herman, MD, PhD

@isaherman85 · X

Really cool study elucidating the neuronal circuit underlying dissociation as seen in #trauma #epilepsy, certain drug use including ketamine for #anesthesia. #optogenetics #Nature #neuroscience Deep posteromedial cortical rhythm in dissociation | Nature https://t.co/FjzabtdMYH

Sep 16, 2020 · 477 followers View post →

Raymond Vazquez, PhD

@rayhv11 · X

Deep posteromedial cortical rhythm in dissociation https://t.co/uNAYfc730L

Sep 16, 2020 · 251 followers View post →

Xin Di

@dixy0 · X

Deep posteromedial cortical rhythm in dissociation https://t.co/IhYYRDHJa6

Sep 16, 2020 · 824 followers View post →

Francis Villatoro

@emulenews · X

#Nature Deep posteromedial cortical rhythm in dissociation https://t.co/bAKYcGokJ3 In layer 2/3 neurons, neither oscillating neurons nor population synchrony were observed; by contrast, layer 5 neurons exhibited synchronous activity cc @xurxomar https://t.co/ujT9VNKyd0

Sep 16, 2020 · 2 likes · 45,157 followers View post →

| Fazlur Rahman |

@engrFazlurRahma · X

Deep posteromedial cortical rhythm in dissociation https://t.co/kFgkGVtPVL https://t.co/ZKf8wB7axt

Sep 16, 2020 · 1,480 followers View post →

Deep posteromedial cortical rhythm in dissociation.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding Ketamine's Role in Inducing Dissociation Effects

Neuroscience of Dissociation: Investigating Brain Activity