Cochrane Database Syst Rev September 2020 PMID 32956536

Magnesium for skeletal muscle cramps.

Scott R Garrison, Christina S Korownyk, Michael R Kolber, G Michael Allan, Vijaya M Musini, Ravneet K Sekhon, Nicolas Dugré

Mentions

112
Peak: 19 in Oct 2020
across 4 sources since May 2019

Extended reach

2,007,064
potential audience

Total likes

6,684

Video views

177,278

Mentions per month

May 2019 – Dec 2025

Where it's discussed

  • X / Twitter66 posts
  • News40 articles
  • Facebook4 posts
  • YouTube2 videos

AI synopsis

What people are saying

Several discussions reinforce the scientific consensus by quoting the Cochrane review, such as 'magnesium doesn’t help' and 'unlikely to provide meaningful prophylaxis,' with tone of skepticism and reliance on authoritative sources. The tone remains factual and dismissive, demonstrating widespread acceptance of the review’s conclusions while some posts show moderate engagement by sharing links and specific data, impacting public understanding of magnesium's limited efficacy.

AgreementStrong disagreement

The majority of discussions emphasize that scientific evidence does not support magnesium's effectiveness for muscle cramps, with many explicitly stating it 'doesn’t help' or referencing the Cochrane review’s conclusions.

InterestNeutral interest

Although users are aware of magnesium's common use, their interest remains neutral as most acknowledge the lack of supporting evidence rather than exploring new perspectives.

EngagementModerate engagement

Some posts engage thoughtfully by referencing systematic reviews and sharing official sources, indicating a moderate level of engagement, but many dismiss the topic outright.

ImpactModerate impact

The discussion appears to influence perceptions, clarifying that magnesium is not proven effective, thus potentially altering how individuals approach supplement use.

Abstract in brief

  • The review investigates whether magnesium supplements effectively prevent skeletal muscle cramps, especially in groups like pregnant women, older adults, athletes, or those with neuromuscular conditions, but finds the evidence remains inconclusive.
  • The researchers conducted a thorough search of multiple medical databases up to September 2019, including randomized controlled trials comparing magnesium with placebo, no treatment, or other therapies, and analyzed data from 11 trials involving 735 participants.
  • Overall, the evidence does not clearly support magnesium's use for cramp prevention, partly because of limited data and mixed results from the included studies, highlighting the need for further high-quality research.

Top posts

Most liked on X and Bluesky
Elliot Tapper
@ebtapper · X

The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help https://t.co/e8LRINt8Bl #MedEd https://t.co/GOlYKvxnSM

Sep 6, 2023 · 26 likes · 5 shares · 42,353 followers View post →
Cochrane Rehabilitation
@CochraneRehab · X

Aug 26, 2021 · 18 likes · 7 shares · 3,105 followers View post →
Dr. Jan-Frieder Harmsen
@247muscle · X

Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older adults experiencing muscle cramps" - conclusion in an updated @CochraneLibrary review. No RCTs on Mg for exercise-associated cramps exist

Oct 6, 2020 · 9 likes · 6 shares · 3,664 followers View post →
Màsters - E.U.Gimbernat
@EUGsurf · X

No, el #magnesio no mejora las #rampas musculares. Revisión sistemática en @CochraneLibrary https://t.co/RB4rikm321 #fisioterapia #investigacion #traslacional #ciencia #evidencia https://t.co/8ejgieKptB

Oct 12, 2020 · 9 likes · 3 shares · 983 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

Interesting Cochrane Review: Magnesium for skeletal muscle cramps https://t.co/5qDw2zR2r6

Sep 22, 2020 · 8 likes · 3,940 followers View post →
Nick Krontiris
@nick_krontiris · X

Magnesium for skeletal muscle cramps https://t.co/zIpR6M9xCo #supplements #supplement #Magnesium #women #pregnancy

Sep 23, 2020 · 3 likes · 1 share · 19,466 followers View post →

All mentions

Essential Facts About Magnesium Supplements

Before taking a magnesium supplement, it’s important to consider medications that can lower magnesium levels such as diuretics and proton pump inhibitors. Additionally, certain conditions like chronic kidney disease and…

Dr. Sam Bailey · Nov 30, 2021 174,305 views

Effectiveness of Magnesium for Muscle Cramps

The Cochrane Review concludes that magnesium may not be as effective as believed for alleviating muscle cramps, whether during the night or while exercising. This video explores the findings of Garrison et al. on…

Dale Kientopf · Feb 7, 2025 1,292 views
Alper Akyüz
@AkyzAlper · X

@nightingaleyan @turkoshitp0st https://t.co/ahXFL9XUYU

Sep 3, 2025 · 1 like · 854 followers View post →
MagTabSR
@mag_tabSR · X

"Magnesium is one of the minerals required by human body for nerve transmission[6] and muscle contraction[7]" from What is the role of magnesium for skeletal muscle cramps? A Cochrane Review summary with commentary. #magnesium #magtabsr #magnesiumlactate #sustainedrelese https://t.co/ZfVGQ9lz78

Jun 25, 2025 · 2 followers View post →
Psy4ist
@psy4ist · X

@iamdvk3 Non. Pour le sport, ca sert à rien. (Cf petite revue). Pour les crampes non plus (Cf Cochrane). https://t.co/Fta5h3U2Mz https://t.co/rqT601obGh.

Apr 14, 2025 · 470 followers View post →
Architect/Nurse®(Mrs).
@PweedyTofer · X

RT @ebtapper: The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help…

Sep 7, 2023 · 5 shares · 5,495 followers View post →
Shrinivas Bishu
@IBDimmunology · X

RT @ebtapper: The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help…

Sep 7, 2023 · 5 shares · 3,036 followers View post →
김정한 Jeong Han Kim
@DrJHK · X

RT @ebtapper: The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help…

Sep 7, 2023 · 5 shares · 2,312 followers View post →
Mouhand Mohamed, MD, MSc
@MouhandMD · X

RT @ebtapper: The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help…

Sep 7, 2023 · 5 shares · 1,890 followers View post →
transplantrockstar (he/him)
@tx_rockstar · X

RT @ebtapper: The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help…

Sep 6, 2023 · 5 shares · 2,323 followers View post →
Elliot Tapper
@ebtapper · X

The first thing many people think about when it comes to the treatment of muscle cramps is magnesium Sadly mag doesn’t help https://t.co/e8LRINt8Bl #MedEd https://t.co/GOlYKvxnSM

Sep 6, 2023 · 26 likes · 5 shares · 42,353 followers View post →
Sarasota Sports Medicine
@SRQ_SportsMed · X

What is the role of magnesium for skeletal muscle cramps? A Cochrane Review summary with commentary - PMC https://t.co/eAoxjRmirO https://t.co/S4ATSPb0Uy

Aug 23, 2023 · 78 followers View post →
Lic. Fernando Luna
@NutricionLP · X

Según una revisión sistemática de Cochrane la administración de magnesio ( oral o intravenosa) no reduciría la frecuencia ni la gravedad de los calambres https://t.co/jN6EghL5z3 https://t.co/uGudGH7qyV

Jul 27, 2023 · 3 likes · 353 followers View post →
CochraneIberoamerica
@CochraneIberoam · X

@CochraneNMD Puedes consultar la revisión sistemática publicada en @CochraneNMD aquí:

Jul 19, 2023 · 2 likes · 14,420 followers View post →
Dr Rob
@drhungo · X

@sachinthemoment Meta analysis shows

Jul 3, 2023 · 1 like · 3,176 followers View post →
Bonnie Rawson
@BonnieRawson4 · X

Magnesium for skeletal muscle cramps - PMC https://t.co/W3PmO90IBI

May 24, 2023 · 2 likes · 2,325 followers View post →
Chantel Martiromo
@_Woman_health · X

#Magnesium: Magnesium for skeletal muscle cramps https://t.co/MOXiFchelg

Apr 5, 2023 · 1 like · 354,338 followers View post →
Angela J. White
@50Plushealths · X

#Magnesium: Magnesium for skeletal muscle cramps https://t.co/TZfPMI4c0U

Mar 9, 2023 · 1 like · 284,907 followers View post →
Quarks
@quarkswdr · X

@azur1969 freut uns, dass dir Magnesium hilft. Für alle anderen, die mitlesen: wissenschaftlich bestätigt ist es nicht, dass Magnesium gegen Wadenkrämpfe hilft https://t.co/nsPZG1xFlY

Jan 9, 2023 · 66,643 followers View post →
Kille Tölönen
@Neonomide · X

@hanne_sainio @NikoNiinivirta Ei auta kramppeihin: https://t.co/DZxSFFWBgs

Nov 7, 2022 · 1 like · 927 followers View post →
Kille Tölönen
@Neonomide · X

@SannaHellstrom @NikoNiinivirta Ei auta suonenvetoihin: https://t.co/DZxSFFWBgs

Nov 7, 2022 · 927 followers View post →
Castor
@Castoropollux2 · X

4 things to know before you take Magnesium supplements. Dr. Sam Bailey https://t.co/oUFhY5e50K

May 19, 2022 · 2,918 followers View post →
Saúl Sánchez
@SaulNutri · X

@Rickym_mor Mírate esta

Apr 25, 2022 · 108,053 followers View post →
Nils 中山
@Fripi · X

@RaraSensei @mizunocaitlin That also is not helping, a) because that's basically a myth (see link) and b) because that's coming from the vegetative nerve system https://t.co/4o2RfC2xJ5.

Mar 31, 2022 · 1 like · 1,420 followers View post →
little rascals
@littlerascals5 · X

4 Things to Know Before You Take a Magnesium Supplement https://t.co/ShrYMgsbpY via @YouTube

Dec 3, 2021 · 1,272 followers View post →
Jeremy Thompson
@thompson74d · X

4 Things to Know Before You Take a Magnesium Supplement https://t.co/DHGbSMwipq via @YouTube

Nov 30, 2021 · 291 followers View post →
名前
@akkiii0830 · X

Magnesium for skeletal muscle cramps https://t.co/SwXI8tZPV5

Nov 25, 2021 · 246 followers View post →
Dr. Jan-Frieder Harmsen
@247muscle · X

@chrismccrum Thanks for highlighting this, I agree that I then trust the good old Cochrane review more, wich recently concluded: "It is unlikely that Mg2+ supplementation provides clinically meaningful cramp prophylaxis to older adults experiencing muscle cramps" https://t.co/6Z37XeREHB

Nov 22, 2021 · 1 like · 3,664 followers View post →
Snaccson
@snaccson · X

@SamGrundman @BadMedicalTakes It's a commonly used supplement for cramps. Evidence says it maybe works for pregnant women. I sometimes recommend it as a low risk intervention to try https://t.co/fvKbFf7qa7

Oct 9, 2021 · 24 followers View post →
revaPellenberg
@revaPellenberg · X

RT @CochraneRehab:

Aug 28, 2021 · 7 shares · 377 followers View post →
Ann-Marie Halligan
@amkhalligan · X

RT @CochraneRehab:

Aug 27, 2021 · 7 shares · 316 followers View post →
Bongani Mayosi Health Sciences Library (BMHSL)
@uct_bmhsl · X

RT @CochraneRehab:

Aug 26, 2021 · 7 shares · 1,592 followers View post →
NaO
@spikeoutOXY · X

RT @CochraneRehab:

Aug 26, 2021 · 7 shares · 156 followers View post →
Mac Keith Press
@mackeithpress · X

RT @CochraneRehab:

Aug 26, 2021 · 7 shares · 2,057 followers View post →
JoaquimLamora
@JoaquimLamora · X

RT @CochraneRehab:

Aug 26, 2021 · 7 shares · 1,133 followers View post →
Dr.cpradeau.mpr
@c_pradeau · X

RT @CochraneRehab:

Aug 26, 2021 · 7 shares · 60 followers View post →
Cochrane Rehabilitation
@CochraneRehab · X

Aug 26, 2021 · 18 likes · 7 shares · 3,105 followers View post →
DrRPalmquist
@DrPalmquist · X

Magnesium for skeletal muscle cramps - PubMed https://t.co/LFFFRLofuv

Mar 24, 2021 · 1 like · 3,171 followers View post →
Madison Irwin
@MIrwinPharmD · X

“It is unlikely that magnesium supplementation provides clinically meaningful cramp prophylaxis to older adults experiencing skeletal muscle cramps.” ...it can be quite effective, however, for causing N/V/D. https://t.co/Xfko12bjHP

Oct 18, 2020 · 2 likes · 104 followers View post →
Albert Blanch
@arteta_05 · X

RT @EUGsurf: No, el #magnesio no mejora las #rampas musculares. Revisión sistemática en @CochraneLibrary https://t.co/RB4rikm321 #fisiotera…

Oct 12, 2020 · 3 shares · 790 followers View post →
docjordi
@docjordi · X

RT @EUGsurf: No, el #magnesio no mejora las #rampas musculares. Revisión sistemática en @CochraneLibrary https://t.co/RB4rikm321 #fisiotera…

Oct 12, 2020 · 3 shares · 324 followers View post →
Lluís Puig
@Fisioinquiet · X

RT @EUGsurf: No, el #magnesio no mejora las #rampas musculares. Revisión sistemática en @CochraneLibrary https://t.co/RB4rikm321 #fisiotera…

Oct 12, 2020 · 3 shares · 5,237 followers View post →
Màsters - E.U.Gimbernat
@EUGsurf · X

No, el #magnesio no mejora las #rampas musculares. Revisión sistemática en @CochraneLibrary https://t.co/RB4rikm321 #fisioterapia #investigacion #traslacional #ciencia #evidencia https://t.co/8ejgieKptB

Oct 12, 2020 · 9 likes · 3 shares · 983 followers View post →
Pieter-Jan Vereecke
@PVereecke · X

RT @JFriederHarmsen: Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older ad…

Oct 6, 2020 · 6 shares · 239 followers View post →
jose garcia fuentes
@qf_jgarcia · X

RT @JFriederHarmsen: Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older ad…

Oct 6, 2020 · 6 shares · 484 followers View post →
The Cochrane Library
@CochraneLibrary · X

RT @JFriederHarmsen: Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older ad…

Oct 6, 2020 · 6 shares · 76,855 followers View post →
Braeden Charlton
@BraedenCharlton · X

RT @JFriederHarmsen: Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older ad…

Oct 6, 2020 · 6 shares · 566 followers View post →
Ricardo Mesquita
@ricardoNOmesqui · X

RT @JFriederHarmsen: Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older ad…

Oct 6, 2020 · 6 shares · 3,771 followers View post →
Dr. Jan-Frieder Harmsen
@247muscle · X

Still valid in 2020: "Unlikely that magnesium (Mg) suppl. provides clinically meaningful cramp prophylaxis to older adults experiencing muscle cramps" - conclusion in an updated @CochraneLibrary review. No RCTs on Mg for exercise-associated cramps exist

Oct 6, 2020 · 9 likes · 6 shares · 3,664 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Links_Medicus: Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults – via @CochraneLibrary…

Oct 5, 2020 · 3 shares · 6,702 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @Links_Medicus: Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults – via @CochraneLibrary…

Oct 5, 2020 · 3 shares · 11,353 followers View post →
Carlos V. Sucre
@CVSucre · X

RT @Links_Medicus: Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults – via @CochraneLibrary…

Oct 5, 2020 · 3 shares · 543 followers View post →
Dr. Euclides Cavalcanti
@Links_Medicus · X

Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults – via @CochraneLibrary https://t.co/dYGBr15uiN

Oct 5, 2020 · 2 likes · 3 shares · 29,379 followers View post →
SchNUDELWASSERmann
@schnudelmann · X

@terumodraht @krustytheboss @Entenpilz @Snoozedanger Es ging um Muskelkrämpfe, oder nicht? Dann steigen sie mal von ihrem hohen Roß und lesen sie das. Kein Wunder, daß die internistische ITS nach der Anästhesie ruft, wenn es kritisch wird. https://t.co/ikKGzUNtxG

Oct 2, 2020 · 8,068 followers View post →
Revista Facultad de Salud U. del Cauca, Colombia.
@RevSaludUniCau · X

RT @CochraneLibrary: Magnesium for muscle cramps https://t.co/B5vgBTFEG7 Updated systematic review from @CochraneNMD #supplements #suppleme…

Oct 2, 2020 · 1 share · 786 followers View post →
The Cochrane Library
@CochraneLibrary · X

Magnesium for muscle cramps https://t.co/B5vgBTFEG7 Updated systematic review from @CochraneNMD #supplements #supplement #Magnesium #exercise

Oct 2, 2020 · 1 like · 1 share · 76,855 followers View post →
Salud juntos
@alfonso_casi · X

Magnesio para los calambres del músculo esquelético. Es improbable que los suplementos de magnesio proporcionen una profilaxis de los calambres clínicamente significativa en el caso de pacientes mayores que presentan calambres del músculo esquelético... https://t.co/ptsxsLpHck https://t.co/BDT1fpYDTR

Oct 2, 2020 · 1 like · 8,559 followers View post →
pinacol
@pinacol · X

【コクランレビュー】こむら返りに対するマグネシウム(夜間下肢こむら返りと思われる高齢者において、マグネシウムとプラセボのこむら返りの頻度の差は小さく、統計学的有意差がなかった。) #ペ読 https://t.co/ceqZMNTa5Y

Sep 26, 2020 · 1 like · 1,621 followers View post →
the paper link
@the_paper_link · X

RT @the_paper_link: Trend up+3: **Garrison SR** et al (Cochrane Database Syst Rev) __Magnesium for skeletal muscle cramps__ https://t.co/bE…

Sep 23, 2020 · 1 share · 136 followers View post →
Jeffery Heileson
@jheilesonRD · X

RT @nick_krontiris: Magnesium for skeletal muscle cramps https://t.co/zIpR6M9xCo #supplements #supplement #Magnesium #women #pregnancy

Sep 23, 2020 · 1 share · 825 followers View post →
Nick Krontiris
@nick_krontiris · X

Magnesium for skeletal muscle cramps https://t.co/zIpR6M9xCo #supplements #supplement #Magnesium #women #pregnancy

Sep 23, 2020 · 3 likes · 1 share · 19,466 followers View post →
the paper link
@the_paper_link · X

Trend up+3: **Garrison SR** et al (Cochrane Database Syst Rev) __Magnesium for skeletal muscle cramps__ https://t.co/bE6PLKua5g

Sep 23, 2020 · 1 share · 136 followers View post →
marcelo flores opazo
@flowersmarcelo · X

no study has proven the efficacy of magnesium suppl to prevent exercise-related muscle cramps https://t.co/Y1yB7DSmLs

Sep 22, 2020 · 183 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

Interesting Cochrane Review: Magnesium for skeletal muscle cramps https://t.co/5qDw2zR2r6

Sep 22, 2020 · 8 likes · 3,940 followers View post →
The Curable Recipes
@CurableSmoothie · X

#Magnesium for skeletal muscle cramps https://t.co/dQGAFEAV2Z

Sep 19, 2019 · 1 like · 325,616 followers View post →
The Curable Recipes
@CurableSmoothie · X

Magnesium for skeletal muscle cramps https://t.co/dQGAFEAV2Z

May 8, 2019 · 2 likes · 325,616 followers View post →