The discussions include comments like dismissing the link between long-term pigmentation loss and systemic aging and mentions of possible natural interventions such as calcium pantothenate and antioxidants, with phrases like 'awesome review' indicating appreciation. The tone is casual and somewhat speculative, leading to an overall neutral impact assessment.
AgreementNeither agree nor disagree
The discussions show mixed opinions; some users dismiss the connection between hair greying and systemic aging, while others acknowledge certain factors involved.
InterestModerate interest
Most users find the topic somewhat interesting, especially those mentioning potential interventions like calcium pantothenate and melatonin.
EngagementNeutral engagement
The conversations are relatively superficial, with users referencing the publication broadly without deep analysis or critique.
ImpactNeutral impact
Overall, these discussions seem to have limited influence on changing opinions or driving further research, reflecting a moderate recognition of the topic's importance.
Abstract in brief
Human hair greying begins with a decline in melanin production within hair follicle pigment cells, driven by factors like reduced tyrosinase activity and cell death, with irreversible greying occurring after the depletion of melanocyte stem cells in the hair follicle.
Oxidative damage plays a key role in the process, disrupting melanocyte survival, stem cell maintenance, and enzymatic functions necessary for pigment production, while genetic and hormonal factors also influence greying, though their exact roles are still being researched.
The complex molecular mechanisms underlying greying involve neuroendocrine factors such as hormones and transcription factors that regulate melanocyte activity; however, a definitive model explaining how these factors modulate greying remains undeveloped.]
@celinehalioua + Calcium pantothenate (and likely melatonin + high dose #omega3 (TNF etc inhibition). Awesome review: The biology of human hair greying. 2020 https://t.co/tCu7LN7N4t https://t.co/fE8Serw3k0
Nov 27, 2020 · 22 likes · 2 shares · 2,262 followersView post →
MM
Madam Mitochondria
@Madam_Mito · X
@yeeseak Check this;
“The study of long-term pigmentation loss is likely to promote our understanding of other systemic ageing controls” (This isn’t true at all )
Dec 13, 2023 · 3 likes · 10,665 followersView post →
CS
Cambridge Philosophical Society
@CamPhilSoc · X
Worried about going grey? Don't be, many underlying factors contribute to hair greying and not all are age related. Read: "The biology of human hair greying" in Biological Reviews, Volume 96, Issue 1, February 2021:
https://t.co/qtTYTe0Obr https://t.co/86zECnkNxB
Aug 26, 2021 · 2 likes · 1,686 followersView post →
Canas canicie cabello envejecimiento. Early grey hair may be caused by vitamin B12, iron, copper deficiencies, severe malnutrition, vegetarian diet, or atopia. While dyes can alter hair color, they may cause irritation…
Dr. Robert Kasten explores the causes of gray hair, focusing on genetic factors and oxidative stress. He discusses how antioxidants like melatonin and flavonoids may help preserve hair color and reviews current advanced…
Feb 13, 2024 · 2 shares · 10,665 followersView post →
MM
Madam Mitochondria
@Madam_Mito · X
@yeeseak Check this;
“The study of long-term pigmentation loss is likely to promote our understanding of other systemic ageing controls” (This isn’t true at all )
Dec 13, 2023 · 3 likes · 10,665 followersView post →
KD
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X
The biology of human hair greying https://t.co/bttfppfkgX #Basically
Worried about going grey? Don't be, many underlying factors contribute to hair greying and not all are age related. Read: "The biology of human hair greying" in Biological Reviews, Volume 96, Issue 1, February 2021:
https://t.co/qtTYTe0Obr https://t.co/86zECnkNxB
Aug 26, 2021 · 2 likes · 1,686 followersView post →
Demonstration of Tyrosinase in Melanocytes of the Human Hair ...
News
The biology of human hair greying, Biological Reviews, 96, 1, (107-128), (2020).https://doi.org/10.1111/brv.12648 · Crossref. Andrew G. Messenger,; Rodney D ...
Signaling Pathway Hair Aging | PDF | Reactive Oxygen Species ...
News
96, 107–128. 582, 399–404. doi:10.1038/s41586-020-2352-3 doi:10.1111/brv.12648. Lee, J., van der Valk, W. H., Serdy, S. A., Deakin, C., Kim, J., Le, A. P. ...