PubHawk
September 2020 PMID 32998479

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases.

Fang Luo, Aaron F Sandhu, Wiramon Rungratanawanich, George E Williams, Mohammed Akbar, Shuanhu Zhou, Byoung-Joon Song, Xin Wang

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Mentions

46
Peak: 11 in Sep 2020
across 5 sources since Sep 2020

Extended reach

305,959
potential audience

Total likes

173

Video views

4,931

Mentions per month

Sep 2020 – Nov 2024

Where it's discussed

  • X / Twitter24 posts
  • YouTube8 videos
  • News8 articles
  • Reddit4 posts
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reveal a strong consensus supporting melatonin's regulatory role in autophagy for neurodegenerative diseases, with language indicating excitement and recognition of its potential, such as phrases like 'promising area for future research' and 'significant influence.' The tone and use of technical terms reflect genuine interest and preliminary engagement by the community.

AgreementModerate agreement

Most discussions support the positive role of melatonin in managing neurodegenerative diseases, indicating general agreement with the publication's findings.

InterestHigh interest

The discussions are highly engaging, with many sharing enthusiasm and highlighting the significance of the research, reflecting strong interest.

EngagementModerate engagement

Several posts delve into detailed mechanisms of autophagy and neuronal health, showing moderate to deep engagement.

ImpactModerate impact

The widespread sharing and tagging of related research and fields suggest the publication's influence is recognized as meaningful in neurodegenerative disease research.

Abstract in brief

  • Aging causes the nervous system to deteriorate, involving processes like oxidative stress, mitochondrial problems, and abnormal cell death, which contribute to neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and ALS.
  • Autophagy is a cell process that clears out damaged proteins and organelles, helping maintain neuron health, but if it becomes dysregulated, it can lead to neurodegeneration due to the buildup of misfolded proteins.
  • Melatonin, a hormone that influences sleep and has antioxidant and anti-inflammatory effects, may protect against neurodegenerative diseases by regulating autophagy, making it a promising area for future research and therapy development.
Read the full abstract

Top posts

Most liked on X and Bluesky
IberianCitizen
@IberianCitizen · X

Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S https://t.co/u74RNUCrtN

Oct 3, 2020 · 26 likes · 4 shares · 12,926 followers View post →
J P Fanton
@HealthyFellow · X

Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @_INPST @TheAgingField @humanOS_me @deNutrients @DrPalmquist @NathanMDCunha @NaumovskiNenad @Domenico_Sergi9 @AndrewMcKune #health #hormone #medicine #sleep

Sep 28, 2020 · 18 likes · 8 shares · 26,028 followers View post →
Víctor Senovilla
@VictorSenovilla · X

La melatonina como agente regulador de la autofagia (promoción/inhibición) y su papel en las enfermedades degenerativas del sistema nervioso. https://t.co/tS5RGfgI2P https://t.co/oSCrZWsp67

Mar 1, 2021 · 13 likes · 3 shares · 20,995 followers View post →
Agingdoc
@agingdoc1 · X

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases https://t.co/F4Mkg0lqVK

Feb 26, 2021 · 4 likes · 41,602 followers View post →
KOJI@プライマルコーチ
@kojija · X

神経変性 ニューロンにおける異常なオートファジー調節が →不規則なタンパク質の蓄積と沈着 →恒常性変化と神経変性 オートファジーは両刃の剣：プログラム細胞死に関する 〇保護作用と 〇損傷経路 オートファジー調節とメラトニンのレビュー https://t.co/l5N3q8wKu4 https://t.co/DIkO4K0SNe

Sep 28, 2020 · 3 likes · 2,311 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 28, 2020 · 8 shares · 123,713 followers View post →

All mentions

fenuso
@fenuso1 · X

RT @VictorSenovilla: La melatonina como agente regulador de la autofagia (promoción/inhibición) y su papel en las enfermedades degenerativa…

Mar 1, 2021 · 3 shares · 125 followers View post →
Ａｌｅｘ Ｄｉｅｚ
@alexdiez77 · X

RT @VictorSenovilla: La melatonina como agente regulador de la autofagia (promoción/inhibición) y su papel en las enfermedades degenerativa…

Mar 1, 2021 · 3 shares · 3,755 followers View post →
Víctor Senovilla
@VictorSenovilla · X

La melatonina como agente regulador de la autofagia (promoción/inhibición) y su papel en las enfermedades degenerativas del sistema nervioso. https://t.co/tS5RGfgI2P https://t.co/oSCrZWsp67

Mar 1, 2021 · 13 likes · 3 shares · 20,995 followers View post →
Agingdoc
@agingdoc1 · X

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases https://t.co/F4Mkg0lqVK

Feb 26, 2021 · 4 likes · 41,602 followers View post →
Brigham and Women's Neurosurgery
@BWHNeurosurgery · X

#PublicationTuesday Congratulations to Xin Wang, Ph.D. et. al. on the publication "Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases" in MDPI: https://t.co/ybjeOsr833 #BWHNeurosurgery #BWH

Jan 26, 2021 · 6,917 followers View post →
alephh
@alephh · X

Melatonin & Autophagy in Neurodegenerative Diseases — Apoptosis & necrosis by excitatory toxins are prevalent in NDDs. Main causes: calcium homeostasis & intracellular oxidative stress + ER stress & mitochondrial dysfunction. MEL➡️⬆️ETC complex I+IV➡️⬆️ATP https://t.co/QNa3PyXBlg https://t.co/Ua4P7MgpRm

Oct 14, 2020 · 388 followers View post →
claimshero.eth
@claimshero__eth · X

RT @IberianCitizen: Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S ht…

Oct 4, 2020 · 4 shares · 128 followers View post →
Mirelis Peralta
@esamuchacha · X

RT @IberianCitizen: Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S ht…

Oct 3, 2020 · 4 shares · 2,560 followers View post →
Jota Eme
@JotaEme93045987 · X

RT @IberianCitizen: Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S ht…

Oct 3, 2020 · 4 shares · 58 followers View post →
Adriakin ✝️
@RastyKiba · X

RT @IberianCitizen: Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S ht…

Oct 3, 2020 · 4 shares · 423 followers View post →
IberianCitizen
@IberianCitizen · X

Melatonina y autofagia en enfermedades neurodegenerativas relacionadas con el envejecimiento https://t.co/EvFjTYPx2S https://t.co/u74RNUCrtN

Oct 3, 2020 · 26 likes · 4 shares · 12,926 followers View post →
Lala
@CNSProteostasis · X

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases. https://t.co/a3eq6hKQsW https://t.co/0gqfszWCjt

Oct 2, 2020 · 20 followers View post →
Sleep Research
@SleepResearch_ · X

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases. https://t.co/aswubeQ4QG

Oct 2, 2020 · 7,259 followers View post →
Neuropsicologo
@CHRISTIANGEL76 · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 29, 2020 · 8 shares · 295 followers View post →
Olskis1
@Olskis1 · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 29, 2020 · 8 shares · 159 followers View post →
CHSeaton
@COSseaton · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 29, 2020 · 8 shares · 5,927 followers View post →
Archives.of.Aging
@League_of_Grey · X

Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases https://t.co/CpU7jSO5ka by @MDPIOpenAccess #diseases

Sep 29, 2020 · 142 followers View post →
Michael Carmody
@m_carmody · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 29, 2020 · 8 shares · 184 followers View post →
Sergey Minaev
@sminaev2015 · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 29, 2020 · 8 shares · 31,475 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 28, 2020 · 8 shares · 123,713 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 28, 2020 · 8 shares · 10,274 followers View post →
KOJI@プライマルコーチ
@kojija · X

神経変性 ニューロンにおける異常なオートファジー調節が →不規則なタンパク質の蓄積と沈着 →恒常性変化と神経変性 オートファジーは両刃の剣：プログラム細胞死に関する 〇保護作用と 〇損傷経路 オートファジー調節とメラトニンのレビュー https://t.co/l5N3q8wKu4 https://t.co/DIkO4K0SNe

Sep 28, 2020 · 3 likes · 2,311 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @HealthyFellow: Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @…

Sep 28, 2020 · 8 shares · 3,165 followers View post →
J P Fanton
@HealthyFellow · X

Review: #Melatonin & #Autophagy in #Aging-Related #Neurodegenerative #Diseases https://t.co/ThHnne6ZWp Attn: @_atanas_ @_INPST @TheAgingField @humanOS_me @deNutrients @DrPalmquist @NathanMDCunha @NaumovskiNenad @Domenico_Sergi9 @AndrewMcKune #health #hormone #medicine #sleep

Sep 28, 2020 · 18 likes · 8 shares · 26,028 followers View post →