Why and How Vaccines Work.

Akiko Iwasaki, Saad B Omer

October 2020

Synopsis of Social media discussions

The overall sentiment reflects curiosity and a recognition of the importance of understanding vaccine mechanisms, exemplified by posts asking for explanations from medical professionals and referencing scientific articles. However, there are also critical remarks and dismissive language that reveal ongoing skepticism and social divisions regarding vaccine acceptance, illustrating both the influence and the challenges of disseminating scientific information in public discussions.

A
Agreement
 Neither agree nor disagree

The discussions show mixed feelings, with some posts supporting the science behind vaccines, while others express distrust or skepticism, indicating neutral or divided agreement.

I
Interest
 Moderate level of interest

Many posts show curiosity and a desire to understand how vaccines work, especially through references to explanations by experts and scientific studies.

E
Engagement
 Moderate level of engagement

Some users actively question, challenge, or elaborate on the science, indicating a moderate level of engagement; others dismiss or criticize the discussions, which slightly lowers engagement.

I
Impact
 Moderate level of impact

The discussions highlight the importance of vaccine science in forming public trust and combating misinformation, giving them a moderate impact especially in shaping opinions or emphasizing the science behind vaccination.

Social Mentions

YouTube

2 Videos

Bluesky

2 Posts

Twitter

76 Posts

News

2 Articles

Metrics

Video Views

23

Total Likes

342

Extended Reach

515,457

Social Features

82

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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8 views

  • Jeri
    @earthfan.bsky.social (Bluesky)

    Lots of children and older folk in Florida get to die so Republicans can learn what science has known for almost 100 years: Why and how vaccines work to prevent disease that’s followed by death and disability.
    view full post

    September 8, 2025

  • Lisa B.
    @PrettyPenny2007 (Twitter)

    @RobertKennedyJr It is terrible that you do not understand why and how vaccines work or It seems like you are trying to make money for the pharmaceutical companies by making people pay full price for the vaccine if they want them. Are you completely uneducated or just corrupt?
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    September 5, 2025

    1

  • Cindividuality
    @C0nstant_R3ad3r (Twitter)

    @LauraRbnsn I really miss the days when we listened to actual medical experts who used research-based FACTS to explain why and how vaccines work. We need to stop giving stupid people a voice.
    view full post

    April 25, 2025

    1

  • ¡ƙąɬıɛ!
    @katmarmal (Twitter)

    @N0taTwitB0t @JennMGreenberg @DrSuzanneH7 can you explain the ingredients in vaccines and how they work? people study medicine for like 12 years… obviously they learn why and how vaccines work. it’s not like their professors goes vaccines work just bc they do! no further questions!
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    April 22, 2025

    1

  • John
    @klimax149art (Twitter)

    @dudebronicus @Greek_Nikolas @krassenstein You must be slow. I used that to correct my typo not everything is about you. Also nice comeback NPC so edgy and cool. Doesn’t matter you proved my point correct in your original post yet you still are to dumb to realize you described why and how vaccines work.
    view full post

    February 27, 2025

  • Quantum Quasar
    @quantum_quasar (Twitter)

    @j4yn3b0d @narindertweets @RealDeniseWelch When you understand why and how vaccines work come back to me.
    view full post

    February 18, 2025


  • @z0phn.bsky.social (Bluesky)

    Which proves he has no fucking clue why and how vaccines work. Herd immunity requires mandates to be reached. If 20-30% of the misled and poorly educated parents simply stop vaccinating their kids, we all suffer.
    view full post

    December 16, 2024

  • Martha Finkle
    @martha_finkle (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    January 14, 2024

    60

  • Dr Judy VaccinePLUS - Novavax JN1 Feb 25
    @JudyandHuahua (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    January 14, 2024

    60

  • Neon Nexion
    @Neon_nexion (Twitter)

    @iamjohnsnow1 @ClownWorld_ https://t.co/PemtkArBfa
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    January 26, 2023

  • sou16
    @sou16 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    May 3, 2021

    60


  • @That_DarnKat (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    April 1, 2021

    60

  • Zarja Muršič
    @piskotk (Twitter)

    @Matej_Klaric Ja to je zelo zanimivo. Tudi v tem članku opisano. https://t.co/bYRVAWEfLi
    view full post

    March 22, 2021

  • Andrea
    @Walrathis (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 12, 2021

    60

  • Patt Kopp #I’m with her- Kamala
    @mvgal92691 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 7, 2021

    60

  • bfitzinAR
    @bfitzinAR (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 7, 2021

    60

  • 特別期間
    @periodoespecial (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 7, 2021

    60

  • Herodote1789
    @herodote1789 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 5, 2021

    60

  • Matt Dragon @matt_dragon@ioc.exchange
    @matt_dragon (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 5, 2021

    60

  • BarbC
    @BarbC_sweden (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 4, 2021

    60

  • AntiMachineGunDeathInMassMurderistan = 2025ProLife
    @deepvard (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 4, 2021

    60

  • Viv Milano
    @VivMilano (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 4, 2021

    60

  • @thevelvetmeow.bsky.social
    @thevelvetmeow (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 4, 2021

    60

  • Claudio
    @CloudyKant (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • Algernon
    @Algerno42910520 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • David Baker
    @DavidBa69494891 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • little miss little butterfly
    @19_recovery (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • 永添泰子(性暴力から子ども達を守る社会に変えよう)
    @packraty (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • Quitting Xitter
    @BashfordThomas (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 3, 2021

    60

  • yumi ＠gj
    @ygjumi (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 2, 2021

    60

  • Defender of
    @e2dot7182818284 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 2, 2021

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  • Honu
    @honu17755302 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
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    March 2, 2021

    60

  • Carbonara - #ME/CFS #ChronicallyIgnored
    @BettinafightsME (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • FrankenTan
    @FrankenTan (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • IWJ_KB_SPTR
    @IWJ_KB_SPTR (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • ニュークリ
    @Newcli0 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • きゅー
    @beechhangergals (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • Salli Pilcher RN, BSc, DN, QN
    @SalliPilcherNHS (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    March 1, 2021

    60

  • Claire Cozler
    @ClaireCozler (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

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  • Joe Match
    @match_joe (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Alva
    @Alva1588 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Liz Szabo
    @LizSzabo (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Praveen Singh
    @praveenvq (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • ABD ELHALIM HADDED
    @AbdHadded (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • JASMINE☆Jazz
    @JAZZJASMINEJAZZ (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Priceless2020 #FBLC
    @Priceless20201 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • 内田
    @uchida_kawasaki (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Fabrizio Chiodo
    @FabrizioChiodo (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • (((Dorit Reiss)))
    @doritmi (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • (((Liz Ditz))). Mask up, y'all. Viruses are real.
    @lizditz (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • ＨＯＵ　ＳＡＮＪＹＯ
    @PsuRgsSuDC8RNT9 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Janet Masleid
    @LuVD3 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Mike Shimwell
    @MikeShimwell (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • EH
    @ForensicMHSA (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Dr Murphy WeightLoss
    @TakeWeightOffMD (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Tanja
    @joy_pops (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Diane Dewhirst
    @NJdoc (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Richard A. Loftus MD
    @RichardALoftus1 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • TAKEUCHI.F.Satomi 竹内 智美
    @OriorinOriorin1 (Twitter)

    RT @VirusesImmunity: Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses…
    view full post

    February 28, 2021

    60

  • Prof. Akiko Iwasaki
    @VirusesImmunity (Twitter)

    Another possible way in which vaccines can help #longCOVID symptoms is through stimulation of innate immune responses (caused by vaccine-associated PAMPs). Transient inflammation might somehow divert the leukocytes causing #longCOVID (6/) https://t.co/20RYJmuDRR https://t.co/wDdCiQBQ1z
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    February 28, 2021

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    60

  • SACI CBR and TelePT Clinic
    @sacicb (Twitter)

    R6sa5Drn2WC401HhoCq80QAvD_BwE World Health Organization (2020, December 17) How do vaccines work?. Retrieved from https://t.co/2DciSOxPa5 Iwasaki, A., & Omer, S. B. (2020). Why and How Vaccines Work. Cell, 183(2), 290–295. https://t.co/175LeUlWgt
    view full post

    December 17, 2020

  • Zarja Muršič
    @piskotk (Twitter)

    Te snovi sprožijo imunski odziv in jih imenujemo tudi imunogeni. Ravno te moramo predstaviti telesu na varnejši način od naravne okužbe. To naredimo z uporabo cepiv. https://t.co/bYRVAWEfLi 4/n
    view full post

    November 21, 2020

    1

  • Samuel Pushparaj
    @sam_pushparaj (Twitter)

    Back to back good news with COVID-19 vaccine data! Check out the other novel vaccines in clinical trial for COVID-19! Source: "Why and How Vaccines Work" - https://t.co/aAYf9xG9gt https://t.co/ezBH2hTBch
    view full post

    November 17, 2020

    1

  • Ken jean marie
    @kenjeanmarie (Twitter)

    RT @das_seed: Why and How Vaccines Work? https://t.co/CsuCroa07B Brief tweetorial by @VirusesImmunity on this topic
    view full post

    November 3, 2020

    1

  • Nik
    @nik_nik19163049 (Twitter)

    There was this posted today https://t.co/UZIE4B9hk3 How do vaccines work https://t.co/VHZtgrYFmW
    view full post

    November 2, 2020

  • Rachel Burckhardt, Ph.D.
    @RMBurckhardt (Twitter)

    Excellent overview from Dr. @VirusesImmunity about the history, science, and future of #vaccines Help increase vaccine acceptance by getting vaccinated as an example, using #scicomm to combat misinformation, and educating the public on how #VaccinesWork https://t.co/lBHDGOacoF
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    October 27, 2020

    3

    2

  • Salome
    @SasMagalhaes (Twitter)

    RT @vaxhub: #Vaccines have greatly reduced the burden of infectious diseases. However, misinformation and the consequent mistrust of vaccin…
    view full post

    October 21, 2020

    1

  • Vax-Hub
    @vaxhub (Twitter)

    #Vaccines have greatly reduced the burden of infectious diseases. However, misinformation and the consequent mistrust of vaccinations pose a threat to their success and positive impact on global human health.
    view full post

    October 20, 2020

    3

    1

  • Lisa Hill
    @Neuroscience_Dr (Twitter)

    RT @RoslynBill: 'Vaccines save millions of lives from infectious diseases caused by viruses and bacteria'. https://t.co/wUqAOW5Q5K
    view full post

    October 19, 2020

    2

  • rebecca stokes
    @BecsS1970 (Twitter)

    RT @RoslynBill: 'Vaccines save millions of lives from infectious diseases caused by viruses and bacteria'. https://t.co/wUqAOW5Q5K
    view full post

    October 19, 2020

    2

  • Roslyn Bill
    @RoslynBill (Twitter)

    'Vaccines save millions of lives from infectious diseases caused by viruses and bacteria'. https://t.co/wUqAOW5Q5K
    view full post

    October 19, 2020

    6

    2

  • Siddhartha| सिद्धार्थ| సిద్ధార్థ
    @das_seed (Twitter)

    Why and How Vaccines Work? https://t.co/CsuCroa07B Brief tweetorial by @VirusesImmunity on this topic
    view full post

    October 17, 2020

    1

    1

  • 小須田 貴延
    @takanobukosuda (Twitter)

    RT @hichachu: 岩崎明子教授のワクチンに関するコメント→ツィッターが明記されている！驚き！ Commentary Why and How Vaccines Work Akiko Iwasaki1,2,3,7,* and Saad B. Omer4,5,6,8 7Tw…
    view full post

    October 16, 2020

    2

  • 内田
    @uchida_kawasaki (Twitter)

    RT @hichachu: 岩崎明子教授のワクチンに関するコメント→ツィッターが明記されている！驚き！ Commentary Why and How Vaccines Work Akiko Iwasaki1,2,3,7,* and Saad B. Omer4,5,6,8 7Tw…
    view full post

    October 16, 2020

    2

  • seki_yo
    @seki_yo (Twitter)

    RT @hichachu: 岩崎明子教授のワクチンに関するコメント→ツィッターが明記されている！驚き！ Commentary Why and How Vaccines Work Akiko Iwasaki1,2,3,7,* and Saad B. Omer4,5,6,8 7Tw…
    view full post

    October 16, 2020

    2

  • ニューロドクター乱夢
    @hichachu (Twitter)

    岩崎明子教授のワクチンに関するコメント→ツィッターが明記されている！驚き！ Commentary Why and How Vaccines Work Akiko Iwasaki1,2,3,7,* and Saad B. Omer4,5,6,8 7Twitter: @virusesimmunity *Correspondence: akiko.iwasaki@yale.edu https://t.co/iMTNf9H8gP https://t.co/kaAJGUfgU0
    view full post

    October 16, 2020

    1

    2

  • Sandra Rajme
    @SandraRajme (Twitter)


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    October 15, 2020

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  • Antonio Guerrero
    @guerreroespejo (Twitter)

    Se estudian todos los tipos de #vacunas en #COVID. Las vacunas modernas incluyen las basadas en ácidos nucleicos (ARNm, ADN), con vectores virales, partículas similares a virus y de proteínas recombinantes (subunidades) @CellCellPress ✍️@VirusesImmunity
    view full post

    October 15, 2020

    4

  • Why and How Vaccines Work | PDF | Vaccines | Virus

    https://doi.org/10.1016/j.cell.2020.09.040. Vaccines save millions of lives from infectious diseases caused by viruses and bacteria. As the world awaits safe ...
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    ... cell & gene therapies. With several marketed products in the U.S. ... doi: https://doi.org/10.1016/j.urology.2020.09.040; Overactive ...
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Abstract Synopsis

  • Vaccines play a crucial role in saving lives by protecting against deadly diseases caused by viruses and bacteria.
  • The development of COVID-19 vaccines has been a significant achievement, but there are still ongoing challenges to ensure safety and effectiveness.
  • Understanding how vaccines work helps us appreciate the science behind their ability to prevent infections and save millions of lives.]