PubHawk
Ann Neurol February 2021 PMID 33068037

Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study).

David R Lynch, Melanie P Chin, Martin B Delatycki, S H Subramony, Manuela Corti, J Chad Hoyle, Sylvia Boesch, Wolfgang Nachbauer, Caterina Mariotti, Katherine D Mathews, Paola Giunti, George Wilmot, Theresa Zesiewicz, Susan Perlman, Angie Goldsberry

Full text PDF Download social card

Mentions

116
Peak: 7 in Oct 2020
across 4 sources since Oct 2020

Extended reach

192,774
potential audience

Total likes

87

Video views

4,595

Mentions per month

Oct 2020 – Aug 2025

Where it's discussed

  • News92 articles
  • X / Twitter19 posts
  • Facebook3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The collective social discussions reflect strong support and high interest in the study, exemplified by references to professional events, expert comments, and the potential for regulatory approval, showing a focus on the study's promising results and clinical significance.

AgreementStrong agreement

The majority of posts strongly support the significance of the MOXIe study and its positive findings regarding omaveloxolone, highlighting its potential as a treatment for Friedreich ataxia.

InterestHigh interest

Posts show high interest by referencing ongoing discussions at professional sessions, podcasts, and emphasizing the drug's existing application across the U.S., indicating engagement with the topic's relevance.

EngagementModerate engagement

Most discussions include references to clinical trials, expert opinions, and regulatory considerations, which demonstrate a moderate but not deep engagement.

ImpactHigh impact

Posts emphasize that the findings could significantly influence treatment options for Friedreich ataxia, with phrases like 'first treatment' and 'potential therapeutic agent' underscoring high impact.

Top posts

Most liked on X and Bluesky
Neurology Journal
@GreenJournal · X

In this episode of the Neurology Podcast: Dr. Jason Crowell talks with Dr. David Lynch about the use of #omaveloxolone for patients with friedreich ataxia. Listen now! https://t.co/U5gyQ21JtA Related Article: https://t.co/g26HxKcKeH @CureFA_org @jasonlcrowell @ChildrensPhila https://t.co/5o0Myqo1s8

Apr 6, 2023 · 10 likes · 98,201 followers View post →
Nat Rev Neurology
@NatRevNeurol · X

Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study) https://t.co/BWpc7sh1wt

Oct 19, 2020 · 7 likes · 3 shares · 46,505 followers View post →
UCLA Neurology
@UCLANeurology · X

Friedreich's ataxia (FRDA) is a progressive genetic neurodegenerative disorder with no approved treatment. Here, Dr. Susan Perlman found that omaveloxolone significantly improved neurological function, representing a potential therapeutic agent in FRDA. https://t.co/YzylPFpSzP https://t.co/RnjD5yCiHs

Oct 31, 2020 · 7 likes · 4,492 followers View post →
C. Roy Lin, MD, MPH, FAAN
@RoyCLinMD · X

@TheNewANA1 #MovementDisorders SIG session today chaired by @FurrStimming and @KuoMDCerebellum - David Lynch talked about Omaveloxolone in FRDA, already in use across the U.S.! https://t.co/ovaZ3oyid3 https://t.co/fY6HRaIi8O @ANA_journals https://t.co/BbK2mYo2WJ

Sep 11, 2023 · 5 likes · 1 share · 1,615 followers View post →
Neurdle - Neurology Word Game
@Neurdle · X

Neurdle, May 1, 2024: Moxie is the official soft drink of Maine (really!) but also the MOXIe trial, testing the safety and efficacy of omaveloxolone, the first treatment for the progressive genetic neurodegenerative condition of Friedreich ataxia https://t.co/Hr76Wb2oy5.... https://t.co/yXeWlFttVJ

May 2, 2024 · 3 likes · 1,430 followers View post →
Andrew Ullmann
@UllmannFDP · X

Es ist wichtig, dass auch Medikamente, die bereits eine gute Wirkung aufweisen, eine rasche, gerne auch bedingte Zulassung bei seltenen Erkrankungen erhalten. #FriedreichAtaxie ist eine von vielen Krankheiten. Für die Experten: hier die Evidenz: https://t.co/cyywwsYk6Y #ema #fda https://t.co/x655ZTh6w8

Jan 17, 2021 · 2 likes · 2 shares · 6,665 followers View post →

All mentions

Neurdle - Neurology Word Game
@Neurdle · X

Neurdle, May 1, 2024: Moxie is the official soft drink of Maine (really!) but also the MOXIe trial, testing the safety and efficacy of omaveloxolone, the first treatment for the progressive genetic neurodegenerative condition of Friedreich ataxia https://t.co/Hr76Wb2oy5.... https://t.co/yXeWlFttVJ

May 2, 2024 · 3 likes · 1,430 followers View post →
ANA Journals
@ANA_journals · X

RT @RoyCLinMD: @TheNewANA1 #MovementDisorders SIG session today chaired by @FurrStimming and @KuoMDCerebellum - David Lynch talked about Om…

Oct 14, 2023 · 1 share · 1,272 followers View post →
C. Roy Lin, MD, MPH, FAAN
@RoyCLinMD · X

@TheNewANA1 #MovementDisorders SIG session today chaired by @FurrStimming and @KuoMDCerebellum - David Lynch talked about Omaveloxolone in FRDA, already in use across the U.S.! https://t.co/ovaZ3oyid3 https://t.co/fY6HRaIi8O @ANA_journals https://t.co/BbK2mYo2WJ

Sep 11, 2023 · 5 likes · 1 share · 1,615 followers View post →
Neurology Journal
@GreenJournal · X

In this episode of the Neurology Podcast: Dr. Jason Crowell talks with Dr. David Lynch about the use of #omaveloxolone for patients with friedreich ataxia. Listen now! https://t.co/U5gyQ21JtA Related Article: https://t.co/g26HxKcKeH @CureFA_org @jasonlcrowell @ChildrensPhila https://t.co/5o0Myqo1s8

Apr 6, 2023 · 10 likes · 98,201 followers View post →
Progress
@progressnp · X

Phase 2 trials show a significant improvement in neurological function with omaveloxolone, and antioxidant and anti-inflammatory, in Friedreich’s ataxia, with a favourable side effect profile. Friedreich’s ataxia currently has no approved pharmacotherapy: https://t.co/Q4OyINjBlA

Sep 22, 2021 · 203 followers View post →
movedoc
@movedoc · X

Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) https://t.co/yoLTqmq34Q

Mar 31, 2021 · 486 followers View post →
Dirk-Oliver Heckmann
@DirkOHeckmann · X

RT @UllmannMdB: Es ist wichtig, dass auch Medikamente, die bereits eine gute Wirkung aufweisen, eine rasche, gerne auch bedingte Zulassung…

Jan 17, 2021 · 2 shares · 2,608 followers View post →
Andrew Ullmann
@UllmannFDP · X

Es ist wichtig, dass auch Medikamente, die bereits eine gute Wirkung aufweisen, eine rasche, gerne auch bedingte Zulassung bei seltenen Erkrankungen erhalten. #FriedreichAtaxie ist eine von vielen Krankheiten. Für die Experten: hier die Evidenz: https://t.co/cyywwsYk6Y #ema #fda https://t.co/x655ZTh6w8

Jan 17, 2021 · 2 likes · 2 shares · 6,665 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Safety & Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) https://t.co/Ib57pmtBYZ

Jan 10, 2021 · 4,417 followers View post →
Emma Jane Ramstead
@ejramstead · X

RT @tripdatabase: New2Trip: Safety & Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) https://t.co/Ib57pmtBYZ

Dec 27, 2020 · 1 share · 262 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Safety & Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) https://t.co/Ib57pmtBYZ

Dec 26, 2020 · 1 share · 4,417 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Safety & Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) https://t.co/Ib57pmtBYZ

Dec 19, 2020 · 4,417 followers View post →
UCLA Neurology
@UCLANeurology · X

Friedreich's ataxia (FRDA) is a progressive genetic neurodegenerative disorder with no approved treatment. Here, Dr. Susan Perlman found that omaveloxolone significantly improved neurological function, representing a potential therapeutic agent in FRDA. https://t.co/YzylPFpSzP https://t.co/RnjD5yCiHs

Oct 31, 2020 · 7 likes · 4,492 followers View post →
Ataxia and Me CIO 1184030
@Ataxia_and_Me · X

RT @senep_es: Seguridad y eficacia de la #omaveloxolona en la #ataxia de Friedreich (estudio MOXIe) vía Annals of Neurology https://t.co/V…

Oct 22, 2020 · 1 share · 4,110 followers View post →
Sociedad Española de Neurología Pediátrica (SENEP)
@senep_es · X

Seguridad y eficacia de la #omaveloxolona en la #ataxia de Friedreich (estudio MOXIe) vía Annals of Neurology https://t.co/VHtj0ejwoM https://t.co/2HHiOmHfcV

Oct 22, 2020 · 1 like · 1 share · 4,178 followers View post →
Dogukan
@Dogukan49049537 · X

RT @NatRevNeurol: Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study) https://t.co/BWpc7sh1wt

Oct 20, 2020 · 3 shares View post →
Javier Díaz-Nido
@Javier_DiazNido · X

RT @NatRevNeurol: Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study) https://t.co/BWpc7sh1wt

Oct 19, 2020 · 3 shares · 1,834 followers View post →
AtaxiasARG
@AtaxiasARG · X

RT @NatRevNeurol: Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study) https://t.co/BWpc7sh1wt

Oct 19, 2020 · 3 shares · 1,024 followers View post →
Nat Rev Neurology
@NatRevNeurol · X

Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study) https://t.co/BWpc7sh1wt

Oct 19, 2020 · 7 likes · 3 shares · 46,505 followers View post →