Minimum sample size for external validation of a clinical prediction model with a continuous outcome.

Lucinda Archer, Kym I E Snell, Joie Ensor, Mohammed T Hudda, Gary S Collins, Richard D Riley

January 2021

Synopsis of Social media discussions

This collection of discussions demonstrates strong interest through references to recent publications and tools like pmsampsize, emphasizing the article's relevance. Words like 'important work' and mentions of new papers, formulas, and validation challenges reflect a shared recognition of the article's impact on research practices and methodological standards.

A
Agreement
 Moderate agreement

Most discussions acknowledge the importance of the article and its methods, showing general support.

I
Interest
 High level of interest

Participants show high curiosity, frequently referencing new papers, sample size calculations, and validation techniques.

E
Engagement
 Moderate level of engagement

There is active participation, with some users discussing specific aspects like formulas, software tools, and implications for practice, but not in great depth.

I
Impact
 High level of impact

The discussions highlight the significance of proper sample size determination, emphasizing its role in improving model validity and reproducibility.

Social Mentions

YouTube

2 Videos

Facebook

2 Posts

Twitter

265 Posts

TikTok

30 Posts

News

3 Articles

Metrics

Video Views

4,976

Total Likes

1,020

Extended Reach

1,135,472

Social Features

302

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Sample Size Calculation for External Validation of Clinical Prediction Models

Sample Size Calculation for External Validation of Clinical Prediction Models

External validation assesses a model's performance on independent data. This video discusses methods to determine the minimum sample size needed for precise validation, focusing on models predicting continuous outcomes, to ensure reliable real-world application.

Richard_D_Riley

October 18, 2022

3,854 views

Determining Minimal Sample Size for External Validation of Clinical Models

Determining Minimal Sample Size for External Validation of Clinical Models

External validation is crucial for assessing the performance of clinical prediction models on new, independent data to ensure their reliability in real-world settings. The article proposes methods to determine the minimum sample size needed for external validation of models predicting continuous outcomes, using four specifi

Richard_D_Riley

November 19, 2020

1,122 views

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    @ColtonLadbury @5_utr @f2harrell Thanks for mentioning pmsampsize For validation see https://t.co/SQQsaWBZXH https://t.co/LZtDa9MiVh https://t.co/ySdsfKLSts and pmvalsampsize in R and Stata
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  • Gary Collins
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    @matloff @f2harrell @5_utr @arteraAI Sample size of test data is always overlooked. We've published some guidance on this for models predicting a - Continuous outcome (https://t.co/D01lvhyTzF) - Binary outcome (https://t.co/boqtIeIT8o, https://t.co/MznQSxum6n) - Time-to-event outcome (https://t.co/8NP94D8Wch)
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  • Raym Geis MD FSIIM
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    How many of us in radiology AI/CVML externally evaluate models like this? @Richard_D_Riley is an eye opener Sample size calculations for external validation of a clinical prediction model https://t.co/XHduL9wRcJ
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  • Gary Collins
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    @VickersBiostats @f2harrell @mike__kattan @BenVanCalster @ESteyerberg @MaartenvSmeden There's this one predicting fat mass in children https://t.co/rrhbf8tSQl that we use in https://t.co/xsF8lkhbmH and this one predicting FEV1 https://t.co/rUFHgpuYWS that we use in https://t.co/5jDKNNcqAf
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  • Sato Shuntaro｜佐藤俊太朗
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  • Maarten van Smeden
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    @pKariova @lucasojesilva12 Well spotted :). It's a figure from 2018, we have much better suggestions for external validation sample size now: https://t.co/8hN91l2nml https://t.co/v1zzixCE4m https://t.co/hYunAZpaf5 https://t.co/K06naCKa4f
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    #10: 2021 was a year with multiple papers coming out suggesting new sample size requirements for prediction model development and validation. This is a personal favorite Open access
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    @CochraneJapan (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Firdaus Kasim
    @dauskasim (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Robbe Van den Begin
    @Van_den_Begin (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Dom Cushnan ▲
    @DomCushnan (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Holger Cevallos-Valdiviezo
    @HolgerCevallosV (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Beth Stuart
    @bethstuart97 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Francesca Fiorentino
    @Francy_lif (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Laure Wynants @laurewynants.bsky.social
    @laure_wynants (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Ane Appelt
    @cancerphysicist (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Brandon Sherman
    @shermstats (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    September 1, 2021

    48

  • Andrés Fandiño
    @andres_fandino (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • CaTaLiNA Research Initiative
    @CaTaLiNA_Ecu (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • @physpm.bsky.social
    @PhysPM (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Paul Sutcliffe
    @DrPaulSutcliffe (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • @docbio.bsky.social
    @DocBio1509 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Michael McPoon
    @MichaelTCPoon (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Malcolm Macleod #FBPE
    @Maclomaclee (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Ash Paul
    @pash22 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Juan
    @juanpabloz87 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Zoubir Djerada
    @ZD79055334 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Maarten van Smeden
    @MaartenvSmeden (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Eddy Fan
    @efan75 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Kym Snell
    @Kym_Snell (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Gary Weissman
    @garyweissman (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Carlos J. Toro-Huamanchumo
    @CarlosToro_29 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Donald Williams
    @wdonald_1985 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • MK
    @muralijnu1 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Ahmad_I
    @khanabdoosh_ (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Thomas Shanahan (Dr.) MRCEM
    @clifford0584 (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Professor Shakila Thangaratinam
    @thangaratinam (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Abraham E. Gracia R.
    @Abraham_RMI (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Neil O'Connell
    @NeilOConnell (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Michael Becker
    @beckerfuffle (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Félix Balazard
    @felbalazard (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Karandeep Singh
    @kdpsinghlab (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Triad sou.
    @triadsou (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Andrew Clegg
    @drandyclegg (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Arthur Sá Ferreira
    @Arthur_SF_BR (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Gary Collins
    @GSCollins (Twitter)

    RT @Richard_D_Riley: Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical predicti…
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    August 31, 2021

    48

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    Now formally published in Statistics in Medicine: Minimum sample size for external validation of a clinical prediction model with a binary outcome https://t.co/nUHsvgOeOL
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    August 31, 2021

    203

    48

  • Keniajin
    @kenniajin (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    August 18, 2021

    28

  • Stats & Data Science Views
    @StatisticsViews (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    August 17, 2021

    28

  • Dr Raul Pacheco-Vega
    @raulpacheco (Twitter)

    RT @TRIPODStatement: Item 8 in TRIPOD is on sample size. New #openaccess paper on minimum sample size for external validation of a clinical…
    view full post

    July 23, 2021

    17

  • Andrés Fandiño
    @andres_fandino (Twitter)

    RT @TRIPODStatement: Item 8 in TRIPOD is on sample size. New #openaccess paper on minimum sample size for external validation of a clinical…
    view full post

    July 23, 2021

    17

  • Saurav Chatterjee
    @SauravChMD (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 22, 2021

    28

  • Jinn-Yuh Guh
    @guhjy (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 21, 2021

    28

  • Bob Phillips
    @drbobphillips (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 21, 2021

    28

  • rafael mello galliez
    @RafaelGalliez (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 21, 2021

    28

  • Michael Schlussel
    @m_schlussel (Twitter)

    Sample size for externally validating prediction models. Continuous variables: https://t.co/R6D8pVWD74 Binary variables: https://t.co/WnyJ2c286K
    view full post

    July 20, 2021

    2

  • Noel Patson
    @NEPatson (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 20, 2021

    28

  • UEDA yuya(上田 雄也)
    @yuue61 (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 19, 2021

    28

  • Ruben Hernaez
    @ruben_hernaez (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Triad sou.
    @triadsou (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • lucinda.archer
    @LucindaAArcher (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 19, 2021

    28

  • Dalne Eric
    @EricDalne (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 19, 2021

    28

  • JSwaine
    @jillian_swaine (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • @docbio.bsky.social
    @DocBio1509 (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • MK
    @muralijnu1 (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Dan McIsaac
    @mcisaac_d (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 19, 2021

    28

  • Barney Scholefield
    @BarneyUoB (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
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    July 19, 2021

    28

  • Donald Williams
    @wdonald_1985 (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Kym Snell
    @Kym_Snell (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Holger Cevallos-Valdiviezo
    @HolgerCevallosV (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Daniel Thomson
    @djthomson (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Garrett Bullock PT, DPT, DPhil
    @DrGSBullock (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Giovanni Briganti, MD, PhD
    @giovbriganti (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Maarten van Smeden
    @MaartenvSmeden (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Kristian Bernhard Nilsen
    @BernhardNilsen (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Abraham E. Gracia R.
    @Abraham_RMI (Twitter)

    RT @Richard_D_Riley: Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary out…
    view full post

    July 19, 2021

    28

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    Now formally published: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" Many thanks to co-authors @Kym_Snell @TPA_Debray @GSCollins @LucindaAArcher @joie_ensor @MaartenvSmeden Open-access & code here: https://t.co/8OR8XnJtSq
    view full post

    July 19, 2021

    84

    28

  • torniquetecervical
    @BolinhoCruel (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    June 28, 2021

    24

  • Edouard L. Fu
    @FuEdouard (Twitter)

    RT @GSCollins: NEW PAPER (@Richard_D_Riley): "Minimum sample size for external validation of a clinical prediction model with a binary outc…
    view full post

    June 21, 2021

    58

  • Tchoubi Sébastien
    @tsebas2000 (Twitter)

    RT @TRIPODStatement: Item 8 in TRIPOD is on sample size. New #openaccess paper on minimum sample size for external validation of a clinical…
    view full post

    June 8, 2021

    17

  • Bob
    @fluxcapdoodah (Twitter)

    RT @Richard_D_Riley: *** NEW PAPER *** "Minimum sample size for external validation of a clinical prediction model with a binary outcome"…
    view full post

    June 5, 2021

    33

  • William Shi
    @williamyshi (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    June 1, 2021

    24

  • Andrew Yockey, PhD (He/Him)
    @YockeyAndrew (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    June 1, 2021

    24

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    June 1, 2021

    24

  • Ahdab Eskandar | أهداب
    @ahdabfeskandar (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 31, 2021

    24

  • Ram Bajpai
    @RamBajpai16 (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 30, 2021

    24

  • Francisco Lupiáñez-Villanueva
    @flupianez (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 29, 2021

    24

  • rafael mello galliez
    @RafaelGalliez (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Kunhyung Kim
    @pdchrist (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Katie Sheehan
    @KatieJSheehan (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Farah Khalid
    @farahk_sheikh (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Juan
    @juanpabloz87 (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • डॉ. कमल नारायण
    @BloomingInMud (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Julius Center UMC U
    @juliuscenter (Twitter)

    RT @Richard_D_Riley: *** NEW PAPER *** "Minimum sample size for external validation of a clinical prediction model with a binary outcome"…
    view full post

    May 28, 2021

    33

  • Ahmad_I
    @khanabdoosh_ (Twitter)

    RT @Richard_D_Riley: "Minimum sample size for external validation of a clinical prediction model with a binary outcome" - now available on…
    view full post

    May 28, 2021

    24

  • Zachary Cohen
    @DepressionLab (Twitter)

    https://t.co/ZpxjOktysA
    view full post

    April 19, 2021

    3

    1

  • Triad sou.
    @triadsou (Twitter)

    Minimum sample size for external validation of a clinical prediction model with a continuous outcome. Archer L, Snell KIE, Ensor J, Hudda MT, Collins GS, Riley RD. Stat Med 2021;40(1):133-146. https://t.co/1oXJBbkiTE
    view full post

    March 11, 2021

    1

    1

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    This work builds on the closed-form solutions proposed by @LucindaAArcher for sample size requirements when validating models with continuous outcomes @KBiostatistics https://t.co/X8y16UkhUs
    view full post

    February 15, 2021

    6

  • Mohammed Hudda
    @MohammedHudda (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Florian Naudet
    @NaudetFlorian (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Joie Ensor
    @joie_ensor (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Karandeep Singh
    @kdpsinghlab (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    January 20, 2021

    19

  • Stats & Data Science Views
    @StatisticsViews (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Stats & Data Science Views
    @StatisticsViews (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    January 20, 2021

    19

  • Maarten van Smeden
    @MaartenvSmeden (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Gary Collins
    @GSCollins (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Miriam Hattle
    @MiriamHattle (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    RT @LucindaAArcher: What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to che…
    view full post

    January 20, 2021

    9

  • lucinda.archer
    @LucindaAArcher (Twitter)

    What better way to celebrate my first ever first-author paper?? Thank you very much @MiriamHattle Don't forget to check your sample sizes folks... https://t.co/OlGT7uUSU4 https://t.co/TFaJsHVJx7 https://t.co/CtCFxh88en
    view full post

    January 20, 2021

    92

    9

  • Strong Coffee
    @CynthiaMN5 (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    January 3, 2021

    19

  • Munya Dimairo
    @mdimairo (Twitter)

    Minimum sample size for external validation of a clinical prediction model with a continuous outcome https://t.co/xt0UzWVsa8
    view full post

    December 26, 2020

  • Gordon Forbes
    @GordonJForbes (Twitter)

    An unexpected (for me) consequence of recent work on sample size for prognostic models is that it that in some cases the minimum sample size for external validation is greater than that for model development. https://t.co/xIm62YQeq7 https://t.co/WXrr6np8I7
    view full post

    November 17, 2020

    3

  • Munya Dimairo
    @mdimairo (Twitter)

    Minimum sample size for external validation of a clinical prediction model with a continuous outcome https://t.co/faAWFlVyLN
    view full post

    November 14, 2020

  • Brooke Levis
    @blevis_epi (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
    view full post

    November 12, 2020

    13

  • Gordon Forbes
    @GordonJForbes (Twitter)

    RT @MohammedHudda: New paper online this week in @Wiley_Stats led by @LucindaAArcher (@KBiostatistics) Minimum sample size required to exte…
    view full post

    November 12, 2020

    3

  • Garrett Bullock PT, DPT, DPhil
    @DrGSBullock (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
    view full post

    November 12, 2020

    13

  • Ignacio Perez
    @IgnacioPerezR (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
    view full post

    November 12, 2020

    13

  • Ali H.Zayter
    @AliHZayter (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • Kym Snell
    @Kym_Snell (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • lucinda.archer
    @LucindaAArcher (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • nana
    @hasnafifah (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • gavin stewart
    @metanutter (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • Gary Collins
    @GSCollins (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • John Boylan
    @jboylan (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
    view full post

    November 12, 2020

    13

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    RT @TRIPODStatement: In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For m…
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    November 12, 2020

    13

  • TRIPODStatement
    @TRIPODStatement (Twitter)

    In Item 8 of the @TRIPODStatement (https://t.co/tvmkmTn2ND), we ask "Explain how the study size was arrived at". For models predicting continuous outcomes we now have guidance for model development (https://t.co/TqR0cNHffB) and external validation (https://t.co/Rf99xEAxiD) https://t.co/pitDQ08kPR
    view full post

    November 11, 2020

    31

    13

  • Stats & Data Science Views
    @StatisticsViews (Twitter)

    RT @Richard_D_Riley: ICYMI, our new paper in Statistics in Medicine https://t.co/XAfmmfIYNF https://t.co/0f7bK3dIeb
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    November 9, 2020

    4

  • lucinda.archer
    @LucindaAArcher (Twitter)

    RT @Richard_D_Riley: ICYMI, our new paper in Statistics in Medicine https://t.co/XAfmmfIYNF https://t.co/0f7bK3dIeb
    view full post

    November 8, 2020

    4

  • lucinda.archer
    @LucindaAArcher (Twitter)

    RT @MohammedHudda: New paper online this week in @Wiley_Stats led by @LucindaAArcher (@KBiostatistics) Minimum sample size required to exte…
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    November 8, 2020

    3

  • Robert Ancuceanu
    @Rancuceanu (Twitter)

    RT @Richard_D_Riley: ICYMI, our new paper in Statistics in Medicine https://t.co/XAfmmfIYNF
    view full post

    November 8, 2020

    4

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    RT @MohammedHudda: New paper online this week in @Wiley_Stats led by @LucindaAArcher (@KBiostatistics) Minimum sample size required to exte…
    view full post

    November 7, 2020

    3

  • Abraham E. Gracia R.
    @Abraham_RMI (Twitter)

    RT @Richard_D_Riley: ICYMI, our new paper in Statistics in Medicine https://t.co/XAfmmfIYNF
    view full post

    November 7, 2020

    4

  • Abraham E. Gracia R.
    @Abraham_RMI (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    November 7, 2020

    19

  • Mohammed Hudda
    @MohammedHudda (Twitter)

    New paper online this week in @Wiley_Stats led by @LucindaAArcher (@KBiostatistics) Minimum sample size required to externally validate a clinical prediction model with a continuous outcome. https://t.co/irr6lVHSSk Pleasure to be involved in this very important work! https://t.co/tTlevdsWXn
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    November 7, 2020

    9

    3

  • Richard Riley (R²)
    @Richard_D_Riley (Twitter)

    ICYMI, our new paper in Statistics in Medicine https://t.co/XAfmmfIYNF https://t.co/0f7bK3dIeb
    view full post

    November 7, 2020

    19

    4

  • Ram Bajpai
    @RamBajpai16 (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
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    November 6, 2020

    19

  • Dr. Joshuan J. Barboza
    @joshuanbarbozam (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Dr Rasha Abdelsalam Elshenawy
    @salam_rasha (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Zachary Cohen
    @DepressionLab (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Apostolos Fakis
    @apostolosfakis (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    November 5, 2020

    19

  • M. En C. Enrique Ambrocio-Ortiz
    @en_ambrocio (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Samuele Cortese
    @CorteseSamuele (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
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    November 5, 2020

    37

  • Franco De Crescenzo
    @FrancoDecrescen (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Paul Sutcliffe
    @DrPaulSutcliffe (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    November 5, 2020

    19

  • Garrett Bullock PT, DPT, DPhil
    @DrGSBullock (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Antonio-Campos et al ;)
    @aac_phd (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Ramcés Falfán-Valencia
    @RFalfanV (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

  • Miriam Hattle
    @MiriamHattle (Twitter)

    RT @Richard_D_Riley: ** NEW PAPER ** by @LucindaAArcher from @KBiostatistics Minimum sample size for external validation of a clinical pr…
    view full post

    November 5, 2020

    19

  • Firdaus Kasim
    @dauskasim (Twitter)

    RT @GSCollins: NEW PAPER (led by @LucindaAArcher in @Wiley_Stats): "Minimum sample size for external validation of a clinical prediction mo…
    view full post

    November 5, 2020

    37

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Abstract Synopsis

  • External validation is crucial for assessing the performance of clinical prediction models on new, independent data to ensure their reliability in real-world settings.
  • The article proposes methods to determine the minimum sample size needed for external validation of models predicting continuous outcomes, using four specific criteria related to variance explained, calibration, and outcome variability.
  • These methods help researchers plan studies more effectively by estimating the required sample size to achieve precise performance measures or assessing if existing datasets are sufficient, as demonstrated through a case study on predicting fat-free mass in children.]