APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).

Einat Granot-Hershkovitz, Wassim Tarraf, Nuzulul Kurniansyah, Martha Daviglus, Carmen R Isasi, Robert Kaplan, Melissa Lamar, Krista M Perreira, Sylvia Wassertheil-Smoller, Ariana Stickel, Bharat Thyagarajan, Donglin Zeng, Myriam Fornage, Charles S DeCarli, Hector M González

March 2021 Alzheimers Dement

Synopsis of Social media discussions

The discussions express strong support for the study's findings, with posts emphasizing the role of genetics in Alzheimer’s risk among Latinx populations, such as 'a variant associated with cognitive decline in South American groups.' The tone is informative and proactive, reflecting both curiosity about the research and concern over potential health impacts, indicating moderate yet meaningful engagement and recognition of its influence.

A
Agreement
 Moderate agreement

Most discussions acknowledge the significance of the study, emphasizing the genetic risk factors and the importance of protecting at-risk populations.

I
Interest
 High level of interest

The discussions demonstrate high interest, with posts highlighting the study's implications for understanding Alzheimer's risk among Latinx groups.

E
Engagement
 Moderate level of engagement

While some comments briefly mention the genetic findings, others explore preventive measures and implications, showing moderate engagement.

I
Impact
 Moderate level of impact

The posts suggest the research could influence public health awareness and encourage preventive actions, though some comments remain general.

Social Mentions

YouTube

2 Videos

Facebook

3 Posts

Twitter

4 Posts

Blogs

4 Articles

News

6 Articles

Metrics

Video Views

153

Total Likes

36

Extended Reach

11,551

Social Features

19

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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  • Alexandra Badea
    @portokalh (Twitter)

    https://t.co/VXtjF30kOG
    view full post

    September 2, 2021

  • Brigham and Women’s Research
    @BrighamResearch (Twitter)

    Study published in @alzdemjournals from @Tamar_Sofer dives into #genetic risk of #Alzheimer's and #dementia for diverse #Latinx groups https://t.co/cQ9H7d0o12
    view full post

    November 24, 2020

    4

  • Vitor Engrácia Valenti
    @valenti_vitor (Twitter)

    Qual a chance de você ter Alzheimer? Um estudo reforça a influência da genética. A variante genética APOE-e4 está associada ao risco de declínio cognitivo em populações da América do Sul. Se você tem parentes com quadro de Alzheimer, atue na prevenção! https://t.co/mFEFNOM1Ma
    view full post

    November 8, 2020

    2

  • Tamar Sofer
    @tamar_sofer (Twitter)

    I'm happy to share a new publication! https://t.co/kCsg8vs5L8 "APOE alleles’ association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL)"
    view full post

    November 6, 2020

    10

Abstract Synopsis

  • The study found that the impact of APOE alleles on cognitive decline varies among different Hispanic/Latino groups and is influenced by their genetic ancestry, with some groups showing stronger associations.
  • Specifically, APOE 4 increases the risk of significant cognitive decline, especially in Cubans, while APOE 2 appears to be protective against mild cognitive impairment in Puerto Ricans.
  • Amerindian ancestry seems to offer protection against the cognitive risks associated with APOE 4, indicating that genetic background plays a key role in how these alleles affect neurocognitive aging in Latinos.]