PubHawk
December 2020 PMID 33188776

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue.

Yang Liu, Mingyu Yang, Yanxiang Deng, Graham Su, Archibald Enninful, Cindy C Guo, Toma Tebaldi, Di Zhang, Dongjoo Kim, Zhiliang Bai, Eileen Norris, Alisia Pan, Jiatong Li, Yang Xiao, Stephanie Halene

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Mentions

84
Peak: 55 in Nov 2020
across 4 sources since Nov 2020

Extended reach

424,471
potential audience

Total likes

161

Video views

195

Mentions per month

Nov 2020 – May 2024

Where it's discussed

  • X / Twitter66 posts
  • News8 articles
  • Blogs6 articles
  • YouTube4 videos

AI synopsis

What people are saying

The collective discussions reveal enthusiasm for the high-resolution multi-omics method, with influential posts calling it an 'amazing technical advance' and mentioning its ability to map gene and protein activity within tissue sections—highlighting both technical innovation and potential for transformative impact in biological research.

AgreementModerate agreement

Most discussions express support or excitement about the technological advances described in the publication, indicating general agreement on its significance.

InterestHigh interest

The discussions show high curiosity, with many posts highlighting the innovative methods and potential applications, reflecting strong interest.

EngagementModerate engagement

While some posts are merely sharing or acknowledging the publication, others involve technical comments and references, suggesting moderate to active engagement.

ImpactHigh impact

Many posts suggest that this advancement could greatly influence fields like pathology and developmental biology, highlighting its high impactful potential.

Abstract in brief

  • DBiTseq is a high-resolution spatial omics technique that uses microfluidic channels to deliver DNA barcodes onto tissue slides, allowing for the mapping of gene and protein activity directly within tissue sections.
  • The process involves applying two sets of barcodes (A150 and B150) across tissue in a crossflow pattern, which creates unique 2D barcoded "pixels" that identify specific tissue regions, enabling detailed spatial analysis of tissue types and features in early development and disease models.
  • This method produces gene expression data at a very fine scale (10-micron pixels) that match single-cell transcriptomes, making it easy for researchers—regardless of microfluidics experience—to identify and study cell types in various fields like developmental biology, cancer research, neuroscience, and pathology.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Luciano Martelotto
@LGMartelotto · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 46 likes · 12 shares · 10,140 followers View post →
Luciano Martelotto
@LGMartelotto · X

Excited that I might be able to get my hands on this amazing ST device! 2021 is coming good... @hoheyn this is also right along your alley! https://t.co/H2IHtPYTpv

Dec 10, 2020 · 39 likes · 3 shares · 10,140 followers View post →
Cell
@CellCellPress · X

New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/qwGGp8k4MM

Nov 13, 2020 · 36 likes · 11 shares · 262,850 followers View post →
Alex Naka
@gottapatchemall · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/lFborGCgZC https://t.co/RoSaCQ4Fh1

Nov 13, 2020 · 7 likes · 1 share · 5,690 followers View post →
Ziv Shulman Lab
@ZivShulman · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/N5L3ZHBOS2

Nov 14, 2020 · 5 likes · 1 share · 2,940 followers View post →
Zhenpeng Qin
@ZhenpengQin · X

check out the new paper on "High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue" from @RongFan8 and colleagues, published in Cell https://t.co/AOdr4c9ZJE

Nov 14, 2020 · 5 likes · 1 share · 1,099 followers View post →

All mentions

HT Vvang
@xchromosome · X

First demonstration of spatial multi-omics sequencing back to 2020 High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue @CellPressNews https://t.co/VcZAsGTPG2

Oct 20, 2023 · 1,335 followers View post →
Zhiqiang Sha (@zhiqiangsha.bsky.social)
@sha_zhiqiang · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/iINhOaKSYZ

Mar 10, 2023 · 1,151 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Cell paper "High-Spatial-Resolution Multi-Omics Sequencing via…" (https://t.co/09oc7636KT). RRIDs like this improve reproducibility in scientific research. #RRID #reproducibility

Apr 25, 2021 · 161 followers View post →
Robert Homer
@rjhomer57 · X

@Vik_deshpandeMD Why not genomics? https://t.co/WvDCxjTwqb

Jan 14, 2021 · 2 likes · 1,307 followers View post →
M Herrera-Rivero
@HerreraR_biomed · X

This is an awesome technical advance: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue - https://t.co/TfeuyyEp0A

Jan 10, 2021 · 1 like · 181 followers View post →
uFluidix Inc.
@uFluidix · X

#Microfluidic channels can deliver barcodes to the surface of a tissue slide for encoding spatial information resulting in a 2D mosaic of tissue pixels that can be used for spatial co-profiling of gene expression and proteins of interest. https://t.co/iobINsGhZF #multiomics

Jan 8, 2021 · 4 likes · 1 share · 4,478 followers View post →
DryWetty
@DryWetty · X

また新しくRNA・タンパク質発現が空間的に見える手法が。シングルセルと組み合わせるのが流行り。 High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/UBvzpEQiqJ

Dec 11, 2020 · 1 like · 177 followers View post →
lbgbox
@lbgbox · X

RT @LGMartelotto: Excited that I might be able to get my hands on this amazing ST device! 2021 is coming good... @hoheyn this is also righ…

Dec 11, 2020 · 3 shares · 51 followers View post →
Minh Tran
@MinhTran_GK · X

RT @LGMartelotto: Excited that I might be able to get my hands on this amazing ST device! 2021 is coming good... @hoheyn this is also righ…

Dec 11, 2020 · 3 shares · 91 followers View post →
Eric Minwei Liu
@EricM_Liu · X

RT @LGMartelotto: Excited that I might be able to get my hands on this amazing ST device! 2021 is coming good... @hoheyn this is also righ…

Dec 10, 2020 · 3 shares · 933 followers View post →
Luciano Martelotto
@LGMartelotto · X

Excited that I might be able to get my hands on this amazing ST device! 2021 is coming good... @hoheyn this is also right along your alley! https://t.co/H2IHtPYTpv

Dec 10, 2020 · 39 likes · 3 shares · 10,140 followers View post →
Joshua Elkington
@elkingtonxy · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue - https://t.co/Qq2xyoAlqS

Nov 29, 2020 · 3 likes · 31,933 followers View post →
Susan Heavey
@susan_heavey · X

Only just noticed I forgot the link

Nov 27, 2020 · 2 likes · 2,809 followers View post →
Sacha LEBON
@SachaLEBON · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 27, 2020 · 11 shares · 75 followers View post →
CCB_VIB_KUL
@vib_ccb · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 27, 2020 · 11 shares · 1,752 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @PubTrend: Trending on PubMed: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/XJ2Hz…

Nov 21, 2020 · 1 share · 1,989 followers View post →
PubMed Trending
@PubTrend · X

Trending on PubMed: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/XJ2HzOqVhv

Nov 21, 2020 · 1 like · 1 share · 5,154 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @sc_papers: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/06xh3FLDU1 https://t.co/Q…

Nov 16, 2020 · 1 share · 1,989 followers View post →
single cell papers
@sc_papers · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/06xh3FLDU1 https://t.co/QS2mE2EWme

Nov 16, 2020 · 1 share · 305 followers View post →
Biomage
@BiomageLtd · X

"High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue" out now in @CellPressNews. Use of new DBiT-seq technology. Congrats @RongFan8! #scRNAseq #spatialtranscriptomics https://t.co/9ciKn4AVhQ

Nov 16, 2020 · 1,060 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @Osamu_ON: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/YxoYsCUpxE

Nov 15, 2020 · 1 share · 1,989 followers View post →
Osamu Onodera　MD. PhD.
@Osamu_ON · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/YxoYsCUpxE

Nov 15, 2020 · 1 share · 543 followers View post →
Tain Luquez
@TainLuquez · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 15, 2020 · 11 shares · 116 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @ZhenpengQin: check out the new paper on "High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue" from @Ro…

Nov 14, 2020 · 1 share · 1,989 followers View post →
Zhenpeng Qin
@ZhenpengQin · X

check out the new paper on "High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue" from @RongFan8 and colleagues, published in Cell https://t.co/AOdr4c9ZJE

Nov 14, 2020 · 5 likes · 1 share · 1,099 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @ZivShulman: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/N5L3ZHBOS2

Nov 14, 2020 · 1 share · 1,989 followers View post →
Ziv Shulman Lab
@ZivShulman · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/N5L3ZHBOS2

Nov 14, 2020 · 5 likes · 1 share · 2,940 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @ioavlachos: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/9nmAcdpiQb

Nov 14, 2020 · 1 share · 1,989 followers View post →
Ioannis Vlachos // @ioavlachos.bsky.social
@ioavlachos · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/9nmAcdpiQb

Nov 14, 2020 · 1 share · 1,245 followers View post →
Francesca Finotello
@Francesca_Fin_ · X

RT @LabPagani: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/AOYC8VrAct

Nov 14, 2020 · 2 shares · 1,163 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @LabPagani: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/AOYC8VrAct

Nov 14, 2020 · 2 shares · 1,989 followers View post →
Vidhya Ravi
@Vidhya1227 · X

RT @Pluchinolab: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/UdjrmzDjfM

Nov 14, 2020 · 2 shares · 1,083 followers View post →
lbgbox
@lbgbox · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 14, 2020 · 11 shares · 51 followers View post →
Darrol Baker
@darrolb · X

Barcoding in tissue for spatial omics sequencing (DBiT-seq) for co-mapping of mRNAs and proteins in a formaldehyde-fixed tissue slide via next-generation sequencing (NGS) https://t.co/1WvJPXheId

Nov 14, 2020 · 260 followers View post →
Pagani Lab
@LabPagani · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/AOYC8VrAct

Nov 14, 2020 · 1 like · 2 shares · 517 followers View post →
Ranjan Kumar Maji, PhD
@ranjankrmaji · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 14, 2020 · 12 shares · 70 followers View post →
Kelvin Yip
@KelvinHYYip · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 124 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @Pluchinolab: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/UdjrmzDjfM

Nov 13, 2020 · 2 shares · 1,989 followers View post →
Thomas Ashhurst
@TomAsh_1 · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 1,320 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue: Cell https://t.co/UdjrmzDjfM

Nov 13, 2020 · 3 likes · 2 shares · 4,736 followers View post →
Stephen Kearney
@s_j_kearney · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 1,319 followers View post →
James Hadfield
@coregenomics · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 7,103 followers View post →
Harry Sokol
@h_sokol · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 3,383 followers View post →
Camilla Cerutti ☮️
@ccamilla81 · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 486 followers View post →
Dr. Neil Ashley
@NotWIMM · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 1,049 followers View post →
P. stipticus
@bitter_oyster · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 17 followers View post →
Nick Wong AU/MEL
@methylnick · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 3,424 followers View post →
Bree
@BreeKB_ · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 3,697 followers View post →
David Russler-Germain, MD/PhD
@dgermain21 · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 3,662 followers View post →
Ying
@ysha_168 · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 41 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @jsantoyo: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/NrUd3jCoVA

Nov 13, 2020 · 1 share · 1,989 followers View post →
Javier Santoyo
@jsantoyo · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. https://t.co/NrUd3jCoVA

Nov 13, 2020 · 2 likes · 1 share · 6,083 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @gottapatchemall: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/lFborGCgZC https://t…

Nov 13, 2020 · 1 share · 1,989 followers View post →
Jen Li
@DrJenLi_Renal · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 711 followers View post →
Jen Li
@JLi_Renal · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 720 followers View post →
Alex Naka
@gottapatchemall · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/lFborGCgZC https://t.co/RoSaCQ4Fh1

Nov 13, 2020 · 7 likes · 1 share · 5,690 followers View post →
Sharan Janjuha
@sharan_janjuha · X

RT @CellCellPress: New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.…

Nov 13, 2020 · 11 shares · 86 followers View post →
Dartmouth Genomics
@Dart_DNA · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 317 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @Abdul_Squared: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/ecnLlcJVTp

Nov 13, 2020 · 1 share · 1,989 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @LGMartelotto: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 12 shares · 1,989 followers View post →
AbdulAbdul
@Abdul_Squared · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/ecnLlcJVTp

Nov 13, 2020 · 1 share · 579 followers View post →
Luciano Martelotto
@LGMartelotto · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/GHRQez7thd

Nov 13, 2020 · 46 likes · 12 shares · 10,140 followers View post →
Benedict Spinoza ❁
@spinobot · X

RT @genebrew: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/Yfrewd2J9V

Nov 13, 2020 · 1 share · 1,989 followers View post →
Rahul Karnik
@genebrew · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/Yfrewd2J9V

Nov 13, 2020 · 1 share · 144 followers View post →
Cell Genomics
@CellGenomics · X

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/QBSi4xdBQN

Nov 13, 2020 · 2 likes · 7,917 followers View post →
Cell
@CellCellPress · X

New Resource now online: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue https://t.co/qwGGp8k4MM

Nov 13, 2020 · 36 likes · 11 shares · 262,850 followers View post →