J Cosmet Dermatol July 2021 PMID 33206444

Retinoid stability and degradation kinetics in commercial cosmetic products.

Žane Temova Rakuša, Petja Škufca, Albin Kristl, Robert Roškar

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Mentions

17
Peak: 3 in Jan 2022
across 3 sources since Nov 2020

Extended reach

1,356,352
potential audience

Total likes

22,665

Video views

1,080,851

Mentions per month

Nov 2020 – Aug 2025

Where it's discussed

  • X / Twitter10 posts
  • YouTube4 videos
  • News3 articles

AI synopsis

What people are saying

Discussions reflect a general agreement on the importance of stabilizing retinoids, exemplified by comments questioning product stability and mentioning the necessity of proper testing, while tone varies from casual admiration to critical observations about product quality and regulation, indicating moderate engagement and recognition of the article's relevance.

AgreementModerate agreement

Most discussions recognize the importance of stability in retinoids and support the article’s insights on degradation factors, as seen in comments about the significance of testing and formulation differences.

InterestModerate interest

Participants show moderate interest, typically discussing product stability and testing practices rather than delving into detailed scientific analysis.

EngagementModerate engagement

Postings include personal reactions, referencing formulations and advocating for better testing, indicating active engagement with the topic.

ImpactNeutral impact

While some mention the relevance of stability knowledge for consumers and industry, the overall impact is moderate, highlighting awareness but not widespread changes.

Abstract in brief

  • The study investigates how retinoids, used in skincare products for conditions like acne and aging, degrade over time, especially focusing on their stability in commercial cosmetics.
  • Using a specific HPLC-UV method, researchers tracked the stability of various retinoids over six months, finding that most products showed significant degradation, particularly when exposed to light and higher temperatures.
  • The research highlights that retinoid stability depends on the formulation and that newer retinoids like hydroxypinacolone retinoate are more stable; it also emphasizes the need for real-time stability testing over accelerated methods to ensure accurate assessment.

Top posts

Most liked on X and Bluesky
Dr Michelle Wong
@LabMuffin · X

This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly too. Yes, sometimes it's just a rip-off. But sometimes you're paying for extra testing and better formulas. 14/ https://t.co/k2NAkI3oZn

Jan 23, 2022 · 47 likes · 2 shares · 35,059 followers View post →
Dr Michelle Wong
@LabMuffin · X

New video! Best and Worst of The Ordinary https://t.co/c3bVrYRvMI

Jan 31, 2021 · 32 likes · 2 shares · 35,058 followers View post →
doa kozmetik
@doakozmetik · X

Bekleyen retinole ne oluyormuş https://t.co/XsSnZpefnk Serum retinoller ne kadar stabilmiş https://t.co/1s5g3NEuG3

Nov 28, 2024 · 16 likes · 107,030 followers View post →
Dr. Njoki Ngumi
@njokingumi · X

RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…

Jan 24, 2022 · 2 shares · 51,496 followers View post →
Lina Toro
@linatoromua · X

@oldie_laurie A la mano tengo este paper

Feb 19, 2023 · 27,206 followers View post →
สกิน-วิทย์-แอร์เรอร์
@skinwitherror · X

@cakeoftheater เสื่อมง่ายค้าบ เพราะจริงๆวงตระกูล retinoids เบสิคๆ (tretinoin, retinaldehyde, retinol) ก็เสื่อมง่ายด้วยลักษณะทางเคมีอยู่แล้วฮะ ถ้าไม่นับ retinyl ester ก็จะมี hpr retinoate ที่มีงานวิจัยวัด HPLC ว่าเสถียร์ฮะ (doi:10.1111/jocd.13852)

Dec 18, 2021 · 11,364 followers View post →

All mentions

doa kozmetik
@doakozmetik · X

Bekleyen retinole ne oluyormuş https://t.co/XsSnZpefnk Serum retinoller ne kadar stabilmiş https://t.co/1s5g3NEuG3

Nov 28, 2024 · 16 likes · 107,030 followers View post →
Lina Toro
@linatoromua · X

@oldie_laurie A la mano tengo este paper

Feb 19, 2023 · 27,206 followers View post →
saturnlwj
@sugarbrat1204 · X

https://t.co/4oK403GIyd she is such a NERD lmao i love it

Jul 12, 2022 · 1,389 followers View post →
Dr. Njoki Ngumi
@njokingumi · X

RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…

Jan 24, 2022 · 2 shares · 51,496 followers View post →
bil.
@carboxBILicacid · X

RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…

Jan 24, 2022 · 2 shares · 3,148 followers View post →
Dr Michelle Wong
@LabMuffin · X

This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly too. Yes, sometimes it's just a rip-off. But sometimes you're paying for extra testing and better formulas. 14/ https://t.co/k2NAkI3oZn

Jan 23, 2022 · 47 likes · 2 shares · 35,059 followers View post →
สกิน-วิทย์-แอร์เรอร์
@skinwitherror · X

@cakeoftheater เสื่อมง่ายค้าบ เพราะจริงๆวงตระกูล retinoids เบสิคๆ (tretinoin, retinaldehyde, retinol) ก็เสื่อมง่ายด้วยลักษณะทางเคมีอยู่แล้วฮะ ถ้าไม่นับ retinyl ester ก็จะมี hpr retinoate ที่มีงานวิจัยวัด HPLC ว่าเสถียร์ฮะ (doi:10.1111/jocd.13852)

Dec 18, 2021 · 11,364 followers View post →
Beatrix B.
@chikkitita · X

@flonot Ça dépend vraiment des produits, semble-t-il. Certains sont très bien, mais beaucoup ne sont pas suffisamment testés + formules pas très stables. https://t.co/6uyFHPZs1Q

Apr 15, 2021 · 3,104 followers View post →
Dr Michelle Wong
@LabMuffin · X

New video! Best and Worst of The Ordinary https://t.co/c3bVrYRvMI

Jan 31, 2021 · 32 likes · 2 shares · 35,058 followers View post →
Vitamin A papers
@vitamin_A_paper · X

Retinoids stability and degradation kinetics in commercial cosmetic products. https://t.co/pUKdgbkwer https://t.co/UAX6Y3fDOt

Nov 20, 2020 · 632 followers View post →