This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly too. Yes, sometimes it's just a rip-off. But sometimes you're paying for extra testing and better formulas. 14/ https://t.co/k2NAkI3oZn
Retinoid stability and degradation kinetics in commercial cosmetic products.
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Nov 2020 – Aug 2025Where it's discussed
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X / Twitter10 posts
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YouTube4 videos
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News3 articles
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What people are saying
Discussions reflect a general agreement on the importance of stabilizing retinoids, exemplified by comments questioning product stability and mentioning the necessity of proper testing, while tone varies from casual admiration to critical observations about product quality and regulation, indicating moderate engagement and recognition of the article's relevance.
Most discussions recognize the importance of stability in retinoids and support the article’s insights on degradation factors, as seen in comments about the significance of testing and formulation differences.
Participants show moderate interest, typically discussing product stability and testing practices rather than delving into detailed scientific analysis.
Postings include personal reactions, referencing formulations and advocating for better testing, indicating active engagement with the topic.
While some mention the relevance of stability knowledge for consumers and industry, the overall impact is moderate, highlighting awareness but not widespread changes.
Abstract in brief
- The study investigates how retinoids, used in skincare products for conditions like acne and aging, degrade over time, especially focusing on their stability in commercial cosmetics.
- Using a specific HPLC-UV method, researchers tracked the stability of various retinoids over six months, finding that most products showed significant degradation, particularly when exposed to light and higher temperatures.
- The research highlights that retinoid stability depends on the formulation and that newer retinoids like hydroxypinacolone retinoate are more stable; it also emphasizes the need for real-time stability testing over accelerated methods to ensure accurate assessment.
Top posts
Most liked on X and BlueskyNew video! Best and Worst of The Ordinary https://t.co/c3bVrYRvMI
Bekleyen retinole ne oluyormuş https://t.co/XsSnZpefnk Serum retinoller ne kadar stabilmiş https://t.co/1s5g3NEuG3
RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…
@oldie_laurie A la mano tengo este paper
@cakeoftheater เสื่อมง่ายค้าบ เพราะจริงๆวงตระกูล retinoids เบสิคๆ (tretinoin, retinaldehyde, retinol) ก็เสื่อมง่ายด้วยลักษณะทางเคมีอยู่แล้วฮะ ถ้าไม่นับ retinyl ester ก็จะมี hpr retinoate ที่มีงานวิจัยวัด HPLC ว่าเสถียร์ฮะ (doi:10.1111/jocd.13852)
All mentions
Assessing the Stability of Retinoids in Cosmetic Products
The study investigates how retinoids, used in skincare products for conditions like acne and aging, degrade over time, especially focusing on their stability in commercial cosmetics. Researchers used HPLC-UV to track…
Retinoid Stability in Cosmetic Products and Degradation Factors
This study investigates how retinoids, used in skincare for acne and aging, degrade over time, focusing on their stability in commercial cosmetics. Researchers tracked stability over six months, revealing significant…
Why I Do Not Recommend The Ordinary Retinoids for Skincare
This video discusses why I advise against using The Ordinary's retinoids, including retinol and granactive retinoid. The brand has significantly changed skincare approaches, but their retinoids may not be the best…
Nanoretinol Offers Superior Stability and Anti-Aging Benefits
Nanoretinol remains stable for a full year and is 232 times more effective, providing clinically proven anti-aging results in just 56 days. Unlike most retinol products that degrade quickly, nanoretinol offers a…
Bekleyen retinole ne oluyormuş https://t.co/XsSnZpefnk Serum retinoller ne kadar stabilmiş https://t.co/1s5g3NEuG3
@oldie_laurie A la mano tengo este paper
https://t.co/4oK403GIyd she is such a NERD lmao i love it
RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…
RT @LabMuffin: This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly to…
This *isn't* a safe assumption for cosmetics, where this regulation doesn't exist. Stability and tolerability vary wildly too. Yes, sometimes it's just a rip-off. But sometimes you're paying for extra testing and better formulas. 14/ https://t.co/k2NAkI3oZn
@cakeoftheater เสื่อมง่ายค้าบ เพราะจริงๆวงตระกูล retinoids เบสิคๆ (tretinoin, retinaldehyde, retinol) ก็เสื่อมง่ายด้วยลักษณะทางเคมีอยู่แล้วฮะ ถ้าไม่นับ retinyl ester ก็จะมี hpr retinoate ที่มีงานวิจัยวัด HPLC ว่าเสถียร์ฮะ (doi:10.1111/jocd.13852)
@flonot Ça dépend vraiment des produits, semble-t-il. Certains sont très bien, mais beaucoup ne sont pas suffisamment testés + formules pas très stables. https://t.co/6uyFHPZs1Q
New video! Best and Worst of The Ordinary https://t.co/c3bVrYRvMI
Retinoids stability and degradation kinetics in commercial cosmetic products. https://t.co/pUKdgbkwer https://t.co/UAX6Y3fDOt