Nat Commun November 2020 PMID 33235214

Common diseases alter the physiological age-related blood microRNA profile.

Tobias Fehlmann, Benoit Lehallier, Nicholas Schaum, Oliver Hahn, Mustafa Kahraman, Yongping Li, Nadja Grammes, Lars Geffers, Christina Backes, Rudi Balling, Fabian Kern, Rejko Krüger, Frank Lammert, Nicole Ludwig, Benjamin Meder

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Mentions

26
Peak: 10 in Dec 2020
across 5 sources since Nov 2020

Extended reach

99,535
potential audience

Total likes

118

Video views

2,064

Mentions per month

Nov 2020 – Aug 2024

Where it's discussed

  • X / Twitter19 posts
  • Reddit2 posts
  • News2 articles
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The social discussions show a strong overall interest in the biomedical implications, with posts referencing how microRNA profiles could be used as biomarkers for aging and diseases, for example, by mentioning potential for effective treatments. While some comments, such as TammyAlenduff's, are dismissive, others reflect curiosity and recognition of the study’s potential, with phrases like 'check out this video' and 'must consider,' indicating a mix of engagement levels and perceived relevance.

AgreementModerate agreement

Most posts acknowledge the significance of the research, with some expressing support or highlighting its potential implications; however, a few comments, like TammyAlenduff's, show skepticism or dismissiveness.

InterestHigh interest

The majority of discussions demonstrate high interest, with references to biomarkers, aging, and potential treatments, reflecting curiosity and engagement with the subject matter.

EngagementModerate engagement

Posts include comments about potential applications and detailed references to other experts and media, indicating a moderate level of thoughtful engagement, though some simply share or retweet without deep analysis.

ImpactModerate impact

The consensus hints at the research's potential impact on diagnostics and personalized medicine, although this is not uniformly emphasized across discussions, resulting in a moderate impact score.

Abstract in brief

  • The study analyzed blood samples from over 1,300 healthy individuals and found that age has a significant impact on microRNA profiles, more so than sex, with a noticeable shift toward mature microRNA forms as people age.
  • When including data from over 3,000 patients with various diseases, researchers identified specific changes in microRNA profiles associated with aging and different diseases, which could help in diagnosing or predicting these conditions.
  • Computational analysis suggests that changes within blood cells themselves, rather than the number of cells, play a bigger role in altering microRNA profiles during aging and disease, offering insights for developing age-specific blood-based biomarkers.]

Top posts

Most liked on X and Bluesky
Eleanor Sheekey
@EleanorSheekey · X

What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wysscoray and others cool latest publication @NatureComms --> https://t.co/1w28j41FBE via @YouTube #miRNA #aging #biomarker #scicomm #academicYouTube

Dec 1, 2020 · 21 likes · 6 shares · 4,884 followers View post →
Katalin Susztak
@KSusztak · X

Common diseases alter the physiological age-related blood microRNA profile | ⁦@NatureComms⁩ https://t.co/nvRbaaaAEl

Nov 24, 2020 · 10 likes · 1 share · 7,124 followers View post →
Matt Buckley
@MatttBuckley · X

Notes on Fehlmann et al (2020) "Common diseases alter the physiological age-related blood microRNA profile" out of Keller lab. https://t.co/FFa9Yinclu

Nov 28, 2020 · 2 likes · 1,180 followers View post →
Institute of Human Genetics (Homburg/Saar)
@UdSHumangenetik · X

Check out this awesome video @EleanorSheekey or

Dec 2, 2020 · 2 likes · 1 share · 27 followers View post →
Agingdoc
@agingdoc1 · X

An old one, from late November: Common diseases alter the physiological age-related blood microRNA profile https://t.co/fgL5cXcUc3

Jan 14, 2021 · 1 like · 41,929 followers View post →
Hematopoiesis News
@Hema_News · X

From @Saar_Uni & @Stanford:

Nov 25, 2020 · 1 like · 3,369 followers View post →

All mentions

James V. Kohl
@microRNApro · X

@TammyAlenduff Your mental instability exemplifies human idiocy in the context of "Common diseases alter the physiological age-related blood microRNA profile." https://t.co/kawCAPnUvU 11/24/20, and https://t.co/JUlCdTfDUY 8/14/24 Next Generation Sequencing may facilitate effective treatment.

Aug 16, 2024 · 2,574 followers View post →
exRNA
@exRNA · X

#ASIC_Bolger2022 @SettyMagana @OhioState @NationwideKids Common diseases alter the physiological age-related blood microRNA profile https://t.co/gLv8cXT1Lk

Oct 14, 2022 · 2,148 followers View post →
Agingdoc
@agingdoc1 · X

An old one, from late November: Common diseases alter the physiological age-related blood microRNA profile https://t.co/fgL5cXcUc3

Jan 14, 2021 · 1 like · 41,929 followers View post →
Academic YouTubers
@YTacademics · X

RT @UdSHumangenetik: Check out this awesome video @EleanorSheekey or

Dec 4, 2020 · 1 share · 2,106 followers View post →
Tobias Fehlmann
@tobias_fehlmann · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 2, 2020 · 6 shares · 100 followers View post →
Xiangfu (Joey) Zhong
@joey0576 · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 2, 2020 · 6 shares · 329 followers View post →
Institute of Human Genetics (Homburg/Saar)
@UdSHumangenetik · X

Check out this awesome video @EleanorSheekey or

Dec 2, 2020 · 2 likes · 1 share · 27 followers View post →
Fabian Kern
@fabiankern13 · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 2, 2020 · 6 shares · 408 followers View post →
Benoit Lehallier
@blehall · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 1, 2020 · 6 shares · 325 followers View post →
Academic YouTubers
@YTacademics · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 1, 2020 · 6 shares · 2,106 followers View post →
José Luis Ricón Fernández de la Puente
@ArtirKel · X

RT @EleanorSheekey: What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wy…

Dec 1, 2020 · 6 shares · 21,989 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

What are miRNAs and can they be used as biomarkers for aging? In my latest video I cover @tobias_fehlmann @blehall @wysscoray and others cool latest publication @NatureComms --> https://t.co/1w28j41FBE via @YouTube #miRNA #aging #biomarker #scicomm #academicYouTube

Dec 1, 2020 · 21 likes · 6 shares · 4,884 followers View post →
Matt Buckley
@MatttBuckley · X

Notes on Fehlmann et al (2020) "Common diseases alter the physiological age-related blood microRNA profile" out of Keller lab. https://t.co/FFa9Yinclu

Nov 28, 2020 · 2 likes · 1,180 followers View post →
Hematopoiesis News
@Hema_News · X

From @Saar_Uni & @Stanford:

Nov 25, 2020 · 1 like · 3,369 followers View post →
Nutriop Longevity
@nutriop · X

Common diseases alter the physiological age-related blood microRNA profile https://t.co/LBtsgE7qmu https://t.co/WYEBUNWwI2

Nov 25, 2020 · 80 followers View post →
Shubharthi Kar, MD, FISN
@shubharthikar · X

RT @KSusztak: Common diseases alter the physiological age-related blood microRNA profile | ⁦@NatureComms⁩ https://t.co/nvRbaaaAEl

Nov 24, 2020 · 1 share · 2,954 followers View post →
Paul Lopez
@lopezunwired · X

Common diseases alter the physiological age-related blood microRNA profile https://t.co/XN6vFTENA5 #MachineLearning #NatureJournal #AI https://t.co/JIx56u41C8

Nov 24, 2020 · 2,487 followers View post →
Katalin Susztak
@KSusztak · X

Common diseases alter the physiological age-related blood microRNA profile | ⁦@NatureComms⁩ https://t.co/nvRbaaaAEl

Nov 24, 2020 · 10 likes · 1 share · 7,124 followers View post →
Reluctant Quant
@DrMattCrowson · X

RT Common diseases alter the physiological age-related blood microRNA profile https://t.co/IvgtoNKKyJ https://t.co/Ibjk3wtejF

Nov 24, 2020 · 1,260 followers View post →