March 2021 PMID 33253634

A multiscale coarse-grained model of the SARS-CoV-2 virion.

Alvin Yu, Alexander J Pak, Peng He, Viviana Monje-Galvan, Lorenzo Casalino, Zied Gaieb, Abigail C Dommer, Rommie E Amaro, Gregory A Voth

Full text PDF Download social card

Mentions

105

Peak: 31 in May 2021

across 4 sources since Oct 2020

Extended reach

1,054,225

potential audience

Total likes

240

Video views

1,175

Mentions per month

Oct 2020 – Mar 2025

Where it's discussed

X / Twitter80 posts
News17 articles
Blogs6 articles
YouTube2 videos

AI synopsis

What people are saying

Conversations about the publication frequently refer to the remarkable representations of the SARS-CoV-2 virion, with phrases such as 'AMAZING representations' and 'first computational model' showing excitement. The use of emphatic language, like 'new and notable,' reinforces the perceived importance and relevance of the research, indicating a strong collective enthusiasm for the findings and their implications in the field of biophysics.

AgreementStrong agreement

The majority of discussions express strong support for the findings presented in the publication, highlighting the importance of the research.

InterestHigh interest

There is a high level of curiosity displayed, with many individuals expressing excitement about the computational models and visuals related to the virion.

EngagementHigh engagement

Discussions reflect a deep engagement, as many users reference specific methodologies and findings from the research, demonstrating an understanding of the scientific content.

ImpactHigh impact

Posts collectively suggest a belief that the publication will have a significant influence on ongoing COVID-19 research and modeling approaches.

Abstract in brief

A multiscale coarse-grained model of the SARS-CoV-2 virion has been developed to simulate large-scale viral processes, like assembly and entry.
Data from techniques like cryo-electron microscopy and x-ray crystallography were used to create structural models of SARS-CoV-2 proteins, which were then combined into a complete virion model.
The coarse-grained model allows for incorporation of viral behaviors that are challenging to simulate at the atomic level and can be updated as new data becomes available, serving as a resource for COVID-19 research.

Read the full abstract

All mentions

Understanding COVID-19 Vaccines: Myths and Realities Explained

Tienes dudas en ponerte la vacuna contra el COVID-19? This video explores essential information about the different types of vaccines, debunks common myths, and discusses important factors like immunity and variants…

Ciencia en Corto · Aug 3, 2021 1,037 views

Modeling SARS-CoV-2 Interactions with Surfactants in Simulations

This video explores the interactions between surfactants and the SARS-CoV-2 virus using a multiscale coarse-grained model. Insights from cryo-electron microscopy and x-ray crystallography enhance our understanding of…

Marc Domingo · Apr 11, 2024 138 views

Taco Jesse

@TJesse62 · X

RT @CellPressNews: A multiscale coarse-grained model of the SARS-CoV-2 virion https://t.co/nOsBQAVJZM Computational biophysics highlight fr…

Mar 17, 2025 · 1 share · 1,742 followers View post →

Cell Press

@CellPressNews · X

A multiscale coarse-grained model of the SARS-CoV-2 virion https://t.co/nOsBQAVJZM Computational biophysics highlight from @BiophysJ (@BiophysicalSoc) https://t.co/bALYBx8fYz

Mar 17, 2025 · 13 likes · 1 share · 161,499 followers View post →

rizkipradipta

@rizkipradipta · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 27, 2023 · 8 shares · 249 followers View post →

grienne

@grienne2 · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 27, 2023 · 8 shares · 115 followers View post →

Abraham Lincoln

@NoBadPHPolicy · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 14 followers View post →

Jean-Marie Renaudin

@JMarieRenaudin · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 1,226 followers View post →

Sheila Shin

@scshinyahoo · X

RT @CellPressNews: Top cited research from @BiophysJ: A multiscale coarse-grained model of the #SARS-CoV-2 virion @BiophysicalSoc @VothGrou…

Jan 26, 2023 · 1 share · 3,560 followers View post →

Eder Andrés

@ederandres152 · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 939 followers View post →

Roland Baker

@RolandBakerIII · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 8,166 followers View post →

misaki98

@maomaoco123 · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 34 followers View post →

Alberto Román

@alberto_roman83 · X

RT @ejustin46: AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virio…

Jan 26, 2023 · 8 shares · 2,470 followers View post →

Emmanuel

@ejustin46 · X

AMAZING representations + VIDEO of the SARS-CoV-2 VIRION Source : A multiscale coarse-grained model of the SARS-CoV-2 virion https://t.co/7RSHEETqoC https://t.co/ORJZoZbNz5

Jan 26, 2023 · 30 likes · 8 shares · 17,283 followers View post →

Prof. Dr. Sanjeev Bagai

@BagaiDr · X

A multiscale coarse-grained model of the SARS-CoV-2 virion: Biophysical Journal https://t.co/zkecL0jCUX

Jan 26, 2023 · 1 like · 34,726 followers View post →

Cell Press

@CellPressNews · X

Top cited research from @BiophysJ: A multiscale coarse-grained model of the #SARS-CoV-2 virion @BiophysicalSoc @VothGroup https://t.co/dzgYMBZK6h

Jan 26, 2023 · 2 likes · 1 share · 161,499 followers View post →

Neil Gerardo-MRX Chairman- ID#32140089

@NeilGerardo · X

RT @CellPressNews: Read freely available biophysics research from @BiophysJ: A multiscale coarse-grained model of the #SARS-CoV-2 virion @B…

Dec 11, 2022 · 4 shares · 792 followers View post →

Mariola Rivera Reyes

@MariolaPR · X

RT @CellPressNews: Read freely available biophysics research from @BiophysJ: A multiscale coarse-grained model of the #SARS-CoV-2 virion @B…

Dec 11, 2022 · 4 shares · 12,185 followers View post →

Cell Press

@CellPressNews · X

Read freely available biophysics research from @BiophysJ: A multiscale coarse-grained model of the #SARS-CoV-2 virion @BiophysicalSoc @BU_tweets https://t.co/RzCvX5GXzu

Dec 11, 2022 · 6 likes · 4 shares · 161,499 followers View post →

smt

@smtnj163 · X

References Density map: https://t.co/mFNWPvvEgl PDB ID 6VYB, 6XR8, 6WJI , 7ACT, https://t.co/pGdYNLIs1B (Spike protein transmembrane helixes), https://t.co/jdCXZu6INM (Envelope and membrane proteins)

Nov 11, 2021 · 48 followers View post →

smt

@smtnj163 · X

References Overall structure: https://t.co/mFNWPvvEgl PDB ID 6VYB, 6XR8, 6WJI , 7ACT, https://t.co/pGdYNLIs1B (Spike protein transmembrane helixes), https://t.co/jdCXZu6INM (Envelope and membrane proteins)

Nov 3, 2021 · 48 followers View post →

smt

@smtnj163 · X

References Overall structure: https://t.co/mFNWPvvEgl Spike proteins : PDB ID 6VYB, 6XR8, and https://t.co/pGdYNLIs1B (transmembrane helixes) Membrane protein & Envelope protein : https://t.co/jdCXZu6INM Nucleocapsid protein - RNA complex: PDB ID 6WJI and 7ACT

Oct 20, 2021 · 48 followers View post →

smt

@smtnj163 · X

I modeled N protein-RNA complex using PDB ID 6WJI and 7ACT based on this paper. S proteins are modeled using PDB ID 6VYB, 6XR8, and https://t.co/pGdYNLIs1B (transmembrane helixes). M protein and E protein models are from https://t.co/jdCXZu6INM.

Sep 13, 2021 · 48 followers View post →

Chris Myers

@bayouphysicist · X

RT @VothGroup: Read the paper: A multiscale coarse-grained model of the SARS-CoV-2 virion on @BiophysJ https://t.co/MPoTvy2yKk #COVID19 #Vi…

Jun 8, 2021 · 3 shares · 3,297 followers View post →

Chris Myers

@bayouphysicist · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

Jun 3, 2021 · 27 shares · 3,297 followers View post →

miro astore

@miroastore · X

RT @VothGroup: Read the paper: A multiscale coarse-grained model of the SARS-CoV-2 virion on @BiophysJ https://t.co/MPoTvy2yKk #COVID19 #Vi…

Jun 3, 2021 · 3 shares · 1,045 followers View post →

Biophysical Journal

@BiophysJ · X

RT @VothGroup: Read the paper: A multiscale coarse-grained model of the SARS-CoV-2 virion on @BiophysJ https://t.co/MPoTvy2yKk #COVID19 #Vi…

Jun 3, 2021 · 3 shares · 6,327 followers View post →

Voth Group

@VothGroup · X

Jun 2, 2021 · 14 likes · 3 shares · 1,160 followers View post →

Naveen Vasudevan

@kuroonai · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 29, 2021 · 27 shares · 437 followers View post →

Athale Lab: CyCelS

@AthaleLab · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 29, 2021 · 27 shares · 1,514 followers View post →

Hiroshi Fujisaki

@hiro2fuji · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 29, 2021 · 27 shares · 549 followers View post →

Yutaka Maruyama

@drmaruyama · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 29, 2021 · 27 shares · 688 followers View post →

NOR-YSD

@damasimodoki · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 57 followers View post →

Dheeraj Prakaash

@DJ_Biophys · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 407 followers View post →

Alejandra Matamoros

@AMatamorosRecio · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 285 followers View post →

ACS COMP

@ACSCOMP · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 4,102 followers View post →

LucaMonticelli

@lucamakinen · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 328 followers View post →

Tanmoy Sanyal

@hiddenvariable2 · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 291 followers View post →

Priyesh Mohanty

@priyeshmohanty · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 122 followers View post →

Shiv Bharadwaj

@shiv_bharadwaj8 · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 140 followers View post →

Geemi Wellawatte

@GWellawatte · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 1,338 followers View post →

Clari Miserendino

@clarimise · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 1,465 followers View post →

Germán González

@germangfeler · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 3,605 followers View post →

Les Loew

@lesloew · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 1,505 followers View post →

@mtwiteando · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 383 followers View post →

David Sept

@A2DaveSept · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 701 followers View post →

Biophysical Journal

@BiophysJ · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 6,327 followers View post →

Anne Goupil

@anne_goupil · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 707 followers View post →

Sudarshan

@sudarshanb259 · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 522 followers View post →

Shashank Pant

@spant_18 · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 877 followers View post →

Saikat das

@Saikatd15545556 · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 52 followers View post →

Saikat das

@Saikatd15545556 · X

RT @VothGroup: #COVID19 #Covid https://t.co/MPoTvy2yKk #compchem #biophysics https://t.co/2mp3jJqvky

May 28, 2021 · 1 share · 52 followers View post →

Saikat das

@Saikatd15545556 · X

RT @VothGroup: Voth Group creates the first #Computational Model of the entire #virus for #COVID19 read it on @BiophysJ https://t.co/MPoTvy…

May 28, 2021 · 2 shares · 52 followers View post →

PhDs of India

@PhDsofIndia · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 28, 2021 · 27 shares · 10,170 followers View post →

Souvik DE

@desouvik · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 27, 2021 · 27 shares · 597 followers View post →

Voth Group

@VothGroup · X

Voth Group creates the first #Computational Model of the entire #virus for #COVID19 read it on @BiophysJ https://t.co/MPoTvy2yKk #compchem #biophysics https://t.co/P8kwur1TNy https://t.co/tKj0jNOQQD

May 27, 2021 · 5 likes · 2 shares · 1,160 followers View post →

Voth Group

@VothGroup · X

#COVID19 #Covid https://t.co/MPoTvy2yKk #compchem #biophysics https://t.co/2mp3jJqvky https://t.co/tKj0jNOQQD

May 27, 2021 · 1 like · 1 share · 1,160 followers View post →

CompChemBio Bot

@CompChemBioBot · X

RT @VothGroup: The Voth Group creates the first #computational #model of the entire virus responsible for #COVID19 read it on @BiophysJ ht…

May 27, 2021 · 27 shares · 2,757 followers View post →

Voth Group

@VothGroup · X

May 27, 2021 · 93 likes · 27 shares · 1,160 followers View post →

estornuda.me

@EstornudaM · X

New and notable: A multiscale coarse-grained model of the SARS-CoV-2 virion https://t.co/g9sY00l5xe

Apr 19, 2021 · 1 like · 597 followers View post →

Biophysical Journal

@BiophysJ · X

RT @CellPressNews: New and notable: A multiscale coarse-grained model of the #SARS-CoV-2 virion New and Notable @BiophysJ article from John…

Apr 19, 2021 · 3 shares · 6,327 followers View post →

Cell Press

@CellPressNews · X

New and notable: A multiscale coarse-grained model of the #SARS-CoV-2 virion New and Notable @BiophysJ article from John E. Straub @BU_tweets https://t.co/BHN1opZARs https://t.co/5SR8LmOgxE

Apr 16, 2021 · 10 likes · 3 shares · 161,499 followers View post →

Veso

@VGG_Consulting · X

A multiscale coarse-grained model of the SARS-CoV-2 virion https://t.co/X41EmlGz3C

Mar 21, 2021 · 72 followers View post →

Biophysical Journal

@BiophysJ · X

Check out the New and Notable "New and notable: A multiscale coarse-grained model of the SARS-CoV-2 virion" from issue 120/6 here: https://t.co/GUs4S3Vkz3

Mar 18, 2021 · 6,327 followers View post →

Bioplantólogo

@bioplantologo · X

Se ha podido ver con esta investigación que las proteínas de punta de la superficie del virus se mueven de manera coordinada y no de manera independiente o aleatoria. Ref: Yu, Alvin, et al. "A multiscale coarse-grained model of the SARS-CoV-2 virion." Biophysical journal (2020).

Mar 4, 2021 · 1 like · 1,397 followers View post →

Cheryl Amber Dotson

@GODZILLASLAYS65 · X

A multiscale coarse-grained model of the SARS-CoV-2 virion: Biophysical Journal https://t.co/mdJdcYzkcq

Mar 2, 2021 · 1,095 followers View post →

Dr Anthony Martin

@AMAinsight · X

A multiscale coarse-grained model of the SARS-CoV-2 virion: Biophysical Journal https://t.co/y9ynuZLbJy

Feb 28, 2021 · 913 followers View post →

PsychiatryAI.com

@PsychiatryAIcom · X

New and notable: A multiscale coarse-grained model of the SARS-CoV-2 virion. https://t.co/wlJLvpfmbz

Feb 13, 2021 · 435 followers View post →

Jeff “The Enemy” Terry

@nuclear94 · X

RT @BlackPhysicists: A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/tsWrVH9Skq via @BiophysJ #biophysics https://t…

Jan 27, 2021 · 1 share · 5,370 followers View post →

BlackPhysicists

@BlackPhysicists · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/tsWrVH9Skq via @BiophysJ #biophysics https://t.co/yUOW3YPc77

Jan 27, 2021 · 1 share · 25,116 followers View post →

Harrison Pratt

@hwprattii · X

A Multiscale Coarse-Grained Model of the SARS-CoV-2 Virion. With videos, too. https://t.co/oPLFkSOkzt

Jan 8, 2021 · 406 followers View post →

Theoretical Biophysics

@TheoBiophysics · X

#TBrecentpublication @BiophysJ A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/XvtSccZ97U

Dec 5, 2020 · 3,410 followers View post →

Gustavo de M. Seabra

@gmseabra · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/6KHhzjiKse https://t.co/CpNJJs5bxb

Dec 4, 2020 · 3 likes · 560 followers View post →

BlackPhysicists

@BlackPhysicists · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/qvA8DPuI6h via @BiophysJ #biophysics https://t.co/ETrilyHEg6

Nov 29, 2020 · 25,116 followers View post →

BlackPhysicists

@BlackPhysicists · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/W1O2LPUhcd #biophysics https://t.co/s1e8fcxGjK

Oct 8, 2020 · 25,116 followers View post →

Volodymyr Nechyporuk-Zloy

@vnzloy · X

"A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion Alvin Yu et al. bioRxiv. posted 2 October 2020, 10.1101/2020.10.02.323915 https://t.co/zsPWhivPUr" https://t.co/FevGxKQPIA

Oct 4, 2020 · 1,279 followers View post →

Cheryl Amber Dotson

@GODZILLASLAYS65 · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion | bioRxiv https://t.co/orr7EzqNK2

Oct 3, 2020 · 1,095 followers View post →

bxv_biophys

@bxv_biophys · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/YlAO7R23Jr

Oct 2, 2020 · 562 followers View post →

cryoEM Papers

@cryoEM_Papers · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/AWBi1KalRZ

Oct 2, 2020 · 3 likes · 11,823 followers View post →

MBE

@MBELTD · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the COVID-19 pandemic. Computer simulations of complete viral particles can provide theoretical… https://t.co/KdYwmgA1x5

Oct 2, 2020 · 1 like · 3,012 followers View post →

bioRxiv Biophysics

@biorxiv_biophys · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/gELobSKEnN #biorxiv_biophys

Oct 2, 2020 · 2 likes · 5,394 followers View post →

bioRxiv

@biorxivpreprint · X

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion https://t.co/ZEjwRJllhJ #bioRxiv

Oct 2, 2020 · 2 likes · 137,564 followers View post →

A multiscale coarse-grained model of the SARS-CoV-2 virion.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding COVID-19 Vaccines: Myths and Realities Explained

Modeling SARS-CoV-2 Interactions with Surfactants in Simulations