Separation and Enrichment of Yeast by Shape Using Viscoelastic Microfluidics.

Abstract in brief

• The study explores a method to separate and enrich yeast cells based on their shapes using a specialized microfluidic device that involves viscoelastic and Newtonian fluids flowing together, allowing cells of different morphologies to migrate differently.
• The researchers examine how various factors such as flow rates, polymer concentration, and channel length affect the effectiveness of this shape-based separation, ensuring high purity and yield of specific cell shapes for research and industrial uses.
• The results indicate that this technique is label-free, continuous, and preserves cell viability, making it a promising tool for producing uniform yeast populations for biological studies and biotechnological applications.]