Front Plant Sci November 2020 PMID 33329667

Docking Characterization and Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2.

Yue Zhu, De-Yu Xie

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Mentions

109
Peak: 76 in May 2021
across 6 sources since Nov 2020

Extended reach

316,549
potential audience

Total likes

1,004

Video views

71,268

Mentions per month

Nov 2020 – Dec 2025

Where it's discussed

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AI synopsis

What people are saying

The discussions revolve around the promising research on plant-based compounds like polyphenols in dark chocolate, green tea, and grapes, with posts emphasizing their potential to inhibit the virus's main protease. Words like 'reveal,' 'detailed study,' and mentions of 'protect' and 'block' convey an optimistic view of the research's significance, encouraging curiosity and further exploration of natural health strategies.

AgreementModerate agreement

Most discussions acknowledge the potential of plant compounds such as dark chocolate, green tea, and grapes in inhibiting SARS-CoV-2, showing general agreement with the study's findings.

InterestModerate interest

The posts demonstrate moderate curiosity, often highlighting specific foods and the research, indicating a genuine interest in natural remedies and nutritional strategies.

EngagementModerate engagement

Several posts reference scientific studies, personal regimens, and detailed findings, reflecting active engagement with the research on a deeper level.

ImpactModerate impact

The discussions suggest these findings could influence public perception and dietary habits, emphasizing natural options as part of COVID-19 prevention or treatment strategies.

Abstract in brief

  • The study investigates how various flavan3ols and proanthocyanidins, which are plant compounds, can bind to and inhibit the main protease (M) of SARS-CoV-2, the virus responsible for COVID-19, using computer simulations and lab assays.
  • Compounds like procyanidin A2, B2, and certain epicatechins showed strong binding and inhibition of the protease, and extracts from foods like green tea, grapes, cacao, and dark chocolate rich in these compounds also effectively inhibited the enzyme.
  • The results suggest that structural features such as galloylation and oligomerization influence how effectively these plant compounds can bind to and block the virus’s main protease, which could be useful for developing antiviral strategies.]

Top posts

Most liked on X and Bluesky
Concerned Canadian Citizen
@malolisica · X

Dark chocolate. It has a lot going for it -- besides the sinfully good taste. https://t.co/5cIen1kpcY

Oct 14, 2023 · 1 like · 2,917 followers View post →
Abu Hanan
@hanan052020 · X

@Parsifaler 4. https://t.co/Dw1acsDBvo

Mar 13, 2022 · 1 like · 1,227 followers View post →
Wertekreis
@wertekreis · X

#Selbstschutz mit Verbindungen der Inhaltsstoffe in grünem Tee, Muscadine-Trauben, Kakaopulver und dunkler Schokolade gegen #Corona. https://t.co/KyxTVvRFnx Forschungsergebnisse: https://t.co/6fKDDSok8X

Nov 7, 2021 · 1 like · 200 followers View post →
Alpha_unknown
@deeplyonesided · X

@TheShrinkette I think he based it of a Frontier study stating some chemical compounds in Dark Chocolate are able to block the Covid-19 virus frm attaching/replicating itself in blood cells. Promising study bt not the miracle cure he touts it to be https://t.co/EYImHAepdX

May 10, 2021 · 1 like · 70 followers View post →
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All mentions

Concerned Canadian Citizen
@malolisica · X

Dark chocolate. It has a lot going for it -- besides the sinfully good taste. https://t.co/5cIen1kpcY

Oct 14, 2023 · 1 like · 2,917 followers View post →
Pål Bergström ♥️
@palbergstrom · X

@OfIstria @Rosse1111 Den danska visade att det inte hjälper och den från Bangladesh är undermålig. För att vi haft en plandemi och de inte spelade med för att trissade upp antalet döda? Grönt te som är vanligt? Kost? Kan finnas många orsaker. https://t.co/LTc4IIlXhw

Mar 12, 2023 · 4,356 followers View post →
Algorithmus22
@Algorithmus22 · X

RT @PascalJabbourMD: Polyphenols and tannic acid present in wine may protect against Covid-19 in vitro and animal models ! I told you , you…

Oct 1, 2022 · 32 shares · 728 followers View post →
Chval Chvil
@mononokle · X

These are like panacea. https://t.co/rFeAlUmAtD

Sep 1, 2022 · 104 followers View post →
Abu Hanan
@hanan052020 · X

@Parsifaler 4. https://t.co/Dw1acsDBvo

Mar 13, 2022 · 1 like · 1,227 followers View post →
Winston J. Sterling
@WinnyJSterling · X

My covid treatment regimen: Aspirin https://t.co/dXnOp309Pu Melatonin https://t.co/roWJPvsZoP Grapes, dark chocolate, and green tea https://t.co/FaM7G04rXb

Jan 19, 2022 · 40 followers View post →
Dr Philip D Craig
@DrPhilipDCraig1 · X

Can green tea protect us from Covid 19? Finally Revealed! https://t.co/fIUD4dmcU5 via @YouTube

Dec 21, 2021 · 1,037 followers View post →
Earthlings
@GoVeganWorld · X

https://t.co/ezBxSp1GNL Study by NC State College of Agriculture & Life Sciences finds that green tea, muscadine grape & dark chocolate have chemical compounds inhibit an important SARS-CoV-2 enzyme https://t.co/rMiUab0SSm #GreenTea #MuscadineGrapes #DarkChocolate #SARSCoV2 https://t.co/75SxmebkqX

Dec 15, 2021 · 4,270 followers View post →
Wertekreis
@wertekreis · X

#Selbstschutz mit Verbindungen der Inhaltsstoffe in grünem Tee, Muscadine-Trauben, Kakaopulver und dunkler Schokolade gegen #Corona. https://t.co/KyxTVvRFnx Forschungsergebnisse: https://t.co/6fKDDSok8X

Nov 7, 2021 · 1 like · 200 followers View post →
BioHacker
@Biohacker00 · X

https://t.co/1wihnxIZTA

Oct 3, 2021 · 37 followers View post →
Dr Philip D Craig
@DrPhilipDCraig1 · X

Can green tea protect us from Covid 19? Finally Revealed! https://t.co/fIUD4dmcU5 via @YouTube

Aug 22, 2021 · 1,037 followers View post →
DOGKING
@DogkingTech1 · X

@classyIndlady https://t.co/BGKpM081uk

Aug 16, 2021 · 2 followers View post →
Nawapron Onkokesung
@NOnkokesung · X

Just listened to the talk from the authors @PSNA2021. I can eat chocolate without guilt! Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2 https://t.co/BjnIkZyrye

Jul 30, 2021 · 230 followers View post →
The Nattering Naybob
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(2/2) https://t.co/4SwXmhgFOd

Jun 20, 2021 · 226 followers View post →
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May 14, 2021 · 81 shares · 2,258 followers View post →
Vignesh V
@vickydeinsty · X

For those who smirk and scoff that dark chocolates cannot help in fighting covid, Here's a detailed study⬇️⬇️⬇️ Oh! By the way! Even sometime back, NDTVFood had written about how dark chocolates and other foods can stop covid. FYI! https://t.co/UT3GXnLvko

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@deeplyonesided · X

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May 10, 2021 · 1 like · 70 followers View post →
Mr. X
@frnd899 · X

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Feb 19, 2021 · 106 followers View post →
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Chemical compounds in foods can inhibit a key SARS-CoV-2 ...
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Frontiers in Plant Science, 2020; 11 DOI: 10.3389/fpls.2020.601316. Cite This Page: MLA; APA; Chicago. North Carolina State University ...

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Chemical compounds in foods can inhibit a key SARS-CoV-2 enzyme
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DOI: 10.3389/fpls.2020.601316. Provided by North Carolina State University. Citation: Chemical compounds in foods can inhibit a key SARS-CoV-2 ...

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Chemical compounds in foods can block the function of key SARS ...
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doi.org/10.3389/fpls.2020.601316. Currently rated 4.3 by 3 people. Posted in: Biochemistry. Comments (0). Download PDF Copy. We recommend.

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Repeating... besides ECGC from green tea Some exciting research ...
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org/articles/10.3389/fpls.2020.601316/full). Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric ...

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MolecularCloud | What if we already have the technology to cure ...
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DOI: 10.3389/fpls.2020.601316 #nutrition #immunology #virology. more. December 15, 2020 · molecularcloud's profile picture. molecularcloud. •.

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