February 2021 PMID 33532778

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7.

Pengfei Wang, Manoj S Nair, Lihong Liu, Sho Iketani, Yang Luo, Yicheng Guo, Maple Wang, Jian Yu, Baoshan Zhang, Peter D Kwong, Barney S Graham, John R Mascola, Jennifer Y Chang, Michael T Yin, Magdalena Sobieszczyk

Mentions

144
Peak: 88 in Mar 2021
across 5 sources since Jan 2021

Extended reach

845,196
potential audience

Total likes

138

Video views

1,827

Mentions per month

Jan 2021 – Aug 2022

Where it's discussed

  • X / Twitter120 posts
  • News18 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions around the publication are characterized by a tone of concern and scientific curiosity, with posts citing the mutation E484K and resistance data to highlight the challenges posed by variants like B.1.351. Words like 'worrisome,' 'significant resistance,' and mentions of delayed or limited vaccine effectiveness convey a recognition of the article's urgent implications for public health and future research, emphasizing that the findings are highly relevant and potentially transformative.

AgreementModerate agreement

Most discussions acknowledge the significance of the publication, with users referencing its findings on resistance and treatment challenges, reflecting general consensus or recognition of its importance.

InterestNeutral interest
EngagementNeutral engagement
ImpactNeutral impact

Abstract in brief

  • The study highlights that the SARS-CoV-2 variants B117 (UK) and B1351 (South Africa) have mutations in their spike proteins that make them more resistant to neutralization by monoclonal antibodies, convalescent plasma, and vaccine-induced sera.
  • B1351 is especially concerning because it shows a significant resistance to neutralization, largely due to the E484K mutation, and greatly reduces the effectiveness of current antibody-based treatments and vaccines.
  • These findings suggest that new variants with these mutations pose challenges for existing COVID-19 therapies and may compromise the overall protective impact of current vaccines, emphasizing the need for ongoing development of updated therapeutics and vaccines.

Top posts

Most liked on X and Bluesky
笹山登生
@keyaki1117 · X

3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7」 https://t.co/kNl8QNURFJ

Mar 8, 2021 · 47 likes · 30 shares · 28,810 followers View post →
Tomas Pueyo
@tomaspueyo · X

More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work really well. Unfortunately, the South African variant appears to have some resistant to both vaccines & mABs https://t.co/yhBUl6GREh https://t.co/FTIohk0P4K

Jan 27, 2021 · 24 likes · 10 shares · 335,720 followers View post →
Andrew Pavia
@AndrewPaviaMD · X

For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction in Ab response to B.1.1.7 but marked reduction to B.1.351 https://t.co/QKid60ITRy #realtimevaccinechat

Feb 17, 2021 · 15 likes · 7 shares · 2,721 followers View post →
FrezzaLab
@FrezzaLab · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/AY2TJXgbxm

Mar 9, 2021 · 5 likes · 2 shares · 26,938 followers View post →
SEInmunología
@SEinmunologia · X

@DrLejarazu @sev_virologia Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization doi: https://t.co/H8i7ZUaA3a

Jan 29, 2021 · 4 likes · 10,395 followers View post →
Ash Paul
@pash22 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/WkGZ7tWtpg via @BarneyGrahamMD et al https://t.co/8kQO2dtf1a

Mar 15, 2021 · 3 likes · 1 share · 32,311 followers View post →

All mentions

AaronStewart
@PoliticalStew1 · X

@KdwUh @TheRealEddieC @Rectitude2022 The crazy thing is that they knew that delta and other variances had significant immune evasion. https://t.co/OafoXXXmku https://t.co/xjCzwkdrJs

Aug 13, 2022 · 1,021 followers View post →
Billy Uttz (Utah TN)
@TnUtah · X

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 | Nature https://t.co/RlyJYdHa5Y

Sep 29, 2021 · 277 followers View post →
AaronStewart
@PoliticalStew1 · X

@ImSpeaking13 @CWittrodt Or the actual virus. Immune evasion https://t.co/b4DdZJZ5Rd . Reduced sensitivity SARS-CoV-2 https://t.co/CiFCvzU0lT . Antibody Resistance SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/xjCzwjVivk . CDC transition to not monitor Breakthrough cases https://t.co/L5pkLJFMtm

Sep 28, 2021 · 1,021 followers View post →
こうちゃん
@daf_koichi · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/GCKAxtX7PN

Aug 9, 2021 · 51 followers View post →
M Matt Frank
@dmmf7 · X

@DrEricDing @kathy_sherrill “This work is published in Nature, in the paper, “Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7.” A preprint of the study was first posted to BioRxiv on January 26, 2021.” https://t.co/UBYvFtXJgp the vaccines work very well, yet Deng continues to not follow work

Jun 17, 2021 · 2,264 followers View post →
Isatou Sarr
@IsatouSarr4 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/33PNHunJrC

May 20, 2021 · 1 like · 45 followers View post →
acathasidealnoendrest
@achiner · X

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7. Nature 593, 130–135 (2021). - by Wang, P., Nair, M.S., Liu, L. et al. #COVID19 #COVID_19 https://t.co/5bmlvvtiNW

May 16, 2021 · 126 followers View post →
Temmie
@TraderTemmie · X

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 | Nature https://t.co/b32dgRi7Ty

May 9, 2021 · 3,633 followers View post →
GeneSoc
@GeneSoc1983 · X

Wang, P., Nair, M. S., Liu, L., Iketani, S., Luo, Y., Guo, Y., … Ho, D. D. (2021). Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.

May 8, 2021 · 2 likes · 935 followers View post →
つね
@tsune75017200 · X

変異株が現れる度に既存ワクチンへの有効性も考えなくてはならないですね。mRNAの技術で素早い応用は出来ると思いますが,今後もどのような変異株が出現してくるか注目です。 Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/liIKejc2MS

May 6, 2021 · 6 followers View post →
高等夢眠
@NobuKoba1988 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/9FNEKGQn6x Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies https://t.co/v4h4YFwewT 株によるんだろうけど今日のネーチャーでも実験的にはワクチンを回避する可能性が指摘されている

May 5, 2021 · 2 likes · 8,623 followers View post →
Isatou Sarr
@IsatouSarr4 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/33PNHuFkja

May 4, 2021 · 1 like · 45 followers View post →
Preprint Bot
@PreprintBot · X

Apr 12, 2021 · 81 followers View post →
Stephen Pimentel
@StephenPiment · X

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 https://t.co/n2aN49zVUt

Apr 1, 2021 · 12,815 followers View post →
VelveteenMole
@VelveteenMole · X

@RandPaul B.1.351 South African variant is and has been the one showing a pattern of not only increased transmissibility but worse outcomes, with experimental evidence of significant vaccine resistance... Oh look, it's not in your study! https://t.co/f0JjQt6XD4 https://t.co/5ZLjrTmBfA https://t.co/4c3Wo4rO5W

Mar 21, 2021 · 117 followers View post →
sunny
@Sunny7331 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/oMqL9UTbi1

Mar 19, 2021 · 76 followers View post →
Preprint Bot
@PreprintBot · X

Mar 17, 2021 · 81 followers View post →
john morley
@drjohnmorley · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/xkPStL8Gsz

Mar 15, 2021 · 1 like · 8,297 followers View post →
Cancer
@neuron6760 · X

RT @pash22: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/WkGZ7tWtpg via @BarneyGrahamMD et al https://t.co/8…

Mar 15, 2021 · 1 share · 207 followers View post →
Ash Paul
@pash22 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/WkGZ7tWtpg via @BarneyGrahamMD et al https://t.co/8kQO2dtf1a

Mar 15, 2021 · 3 likes · 1 share · 32,311 followers View post →
とらねこ
@2vcr9pNrO9r9h6g · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 15, 2021 · 30 shares · 426 followers View post →
岡本Kジロォ
@K2rooOka · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 14, 2021 · 30 shares · 1,126 followers View post →
Dr Anthony Martin
@AMAinsight · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/dfovBU4z2r

Mar 14, 2021 · 917 followers View post →
c.jumpeR
@creamyjampan · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 14, 2021 · 30 shares · 1,499 followers View post →
PubMed Trending
@PubTrend · X

Trending on PubMed: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7. https://t.co/3B35vuReF9

Mar 13, 2021 · 5,174 followers View post →
Annette Gartland
@netpoette · X

@JaneEva37964120 @trishgreenhalgh @Channel4News Then there's the "accelerated article preview" about antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 that I still need to read! This pandemic has taken me way out of my "comfort zone" as a journalist; not that I ever really had one. But it certainly wasn't science!

Mar 13, 2021 · 5,398 followers View post →
Adam Karaba
@KarabaAdam · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/Ymq9CJYxg1 https://t.co/cSdZTmUIoz - via Researcher (@ResearcherApp)

Mar 12, 2021 · 257 followers View post →
GEG-tech.com
@GEG_tech · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 - Nature | @scoopit https://t.co/W0Lf5HlTQK

Mar 11, 2021 · 58 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Worrisome! Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/zUA4oi6ip7

Mar 10, 2021 · 1 like · 1 share · 32,237 followers View post →
Dijana Tolic
@aristotletruth · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 10, 2021 · 22 shares · 61 followers View post →
Gris
@degogrim · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/vD6MHlcmwj

Mar 10, 2021 · 59 followers View post →
にゅろ, MD
@EBNeuro · X

2021/3/8出版分 twitterでバズった論文 全分野 Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/RM3bLUT2yT Tweets: 1379 COVID-19 南アフリカ株のワクチン耐性に関するbriefing

Mar 10, 2021 · 155 followers View post →
the paper link
@the_paper_link · X

RT @the_paper_link: Trend up+13: Wang P, ..., Ho DD (Nature) __Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7__ https://t.…

Mar 10, 2021 · 1 share · 136 followers View post →
しとらす@京都
@citrus_kyoto · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 1,358 followers View post →
the paper link
@the_paper_link · X

Trend up+13: Wang P, ..., Ho DD (Nature) __Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7__ https://t.co/acblWri24M

Mar 9, 2021 · 1 share · 136 followers View post →
Osman P. Meza
@OsmanpMeza · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/vZUkQA4SaR

Mar 9, 2021 · 62 followers View post →
SPV
@SPVirologia · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/OhzxCmeTGh

Mar 9, 2021 · 66 followers View post →
Luca Tancredi Barone
@lucatbarone · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 9, 2021 · 22 shares · 2,343 followers View post →
bob swede
@bobswede · X

RT @bobswede: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/VqGxUC5qGw

Mar 9, 2021 · 1 share · 411 followers View post →
bob swede
@bobswede · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/VqGxUC5qGw

Mar 9, 2021 · 1 like · 1 share · 411 followers View post →
やまちゃん
@yamasaki_hana · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 1,592 followers View post →
VirTIGOdx
@virtigodx · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/V9BYRA6cK6

Mar 9, 2021 · 5 followers View post →
VirTIGOBio
@virtigobio · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/pVHRourMBX

Mar 9, 2021 · 6 followers View post →
starxgen
@EstrellaPereir1 · X

https://t.co/I16nm8rD7X: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7. https://t.co/eZH5laT0Lt via @GoogleNews

Mar 9, 2021 · 295 followers View post →
Ah-Ram Kim
@ahramkim1128 · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/hnt3KK3GHT

Mar 9, 2021 · 283 followers View post →
Ornella Punzo
@Ornelsss · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 9, 2021 · 22 shares · 1,309 followers View post →
njt
@njtstqb · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 1,590 followers View post →
Tabatha
@araran100 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 17,477 followers View post →
ministero della distruzione del merito|Allan Kafka
@AllanKafka · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 9, 2021 · 22 shares · 537 followers View post →
Kidneya Therapeutics
@kidneya_tx · X

RT @FrezzaLab: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/AY2TJXgbxm

Mar 9, 2021 · 2 shares · 28 followers View post →
Pondering Dyke
@PonderingDyke · X

'Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7' #Covid_19 #B1351 #B117 #Pfizer #Moderna https://t.co/KorqAImV1V (Wang, P. et. al)

Mar 9, 2021 View post →
morningtiger
@morningtigert · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 9, 2021 · 22 shares · 231 followers View post →
山口 真理
@aribaba60 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 843 followers View post →
Glenn Bantug
@gbantug2000 · X

RT @FrezzaLab: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/AY2TJXgbxm

Mar 9, 2021 · 2 shares · 124 followers View post →
Marcus Evans
@MarcuswevansSr · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7: Nature, Published online: 08 March 2021; doi:10.1038/s41586-021-03398-2Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/m8pFHt5Aox

Mar 9, 2021 · 3,592 followers View post →
FrezzaLab
@FrezzaLab · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 | Nature https://t.co/AY2TJXgbxm

Mar 9, 2021 · 5 likes · 2 shares · 26,938 followers View post →
Kashuu
@KenmochiBunko · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 9, 2021 · 30 shares · 825 followers View post →
背乃あぶら
@SAY_A_BLUR · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 1,225 followers View post →
Hirokazu SUZUKI
@ponzalez · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 274 followers View post →
なおちゃん
@imahasi108 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 448 followers View post →
sawa
@sawa884336221 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 106 followers View post →
さむがりなハニー GI NAORIN
@gi_naorin · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 413 followers View post →
komakoma
@komaranjyo25 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 1,425 followers View post →
石油の枯渇が心配
@mgrbq46 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 923 followers View post →
jiri
@jiri1974 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 44 followers View post →
あブラだこす
@aburadakos · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 3,808 followers View post →
紅茶soda
@ichigoTeasoda · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 512 followers View post →
しゃるとりゅずロックのみな隆一。
@leizoko · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 747 followers View post →
nabeoolongtea
@oolongteana · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 474 followers View post →
Hasui Noel®
@noel_hasui · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 1,405 followers View post →
David Usharauli
@3DiMMUNE · X

we see little changes from preprint to peer review in papers these days, especially for #COVID19. Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/cZVdxOlRoF

Mar 8, 2021 · 2 likes · 2,720 followers View post →
宮島正
@yasuokajihei · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares View post →
so sora
@sosorasora3 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 17,278 followers View post →
Kinn-san
@ja8yum · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 10,100 followers View post →
小夜曲
@gZcVrTf8oDQihqL · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 12,547 followers View post →
rosemint
@spearmint33 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 120 followers View post →
Jose_Medel なにもできない役立たず
@jose_medel1945 · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 1,097 followers View post →
margotanako
@margotanako · X

RT @keyaki1117: 3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of…

Mar 8, 2021 · 30 shares · 1,624 followers View post →
笹山登生
@keyaki1117 · X

3月8日公表 南アフリカで最初に発見新型コロナウイルス変異株でワクチンをテストした結果。ファイザーもモデルナも10分の1の効果しかなかった。 原因はE484K変異に対する有効性が低かったため。 研究 「Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7」 https://t.co/kNl8QNURFJ

Mar 8, 2021 · 47 likes · 30 shares · 28,810 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @NG20194: @abledoc @AskDrShashank @Rupalijee @VirusesImmunity Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 (March 8,…

Mar 8, 2021 · 1 share · 32,589 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/IPxIGj5qTO B.1.351 (South African variant now in 20 states) is markedly more resistant to neutralization by convalescent plasma (9.4 fold) and Pfizer or Moderna vaccine sera (10.3-12.4 fold).

Mar 8, 2021 · 18,558 followers View post →
NG20194
@NG20194 · X

@abledoc @AskDrShashank @Rupalijee @VirusesImmunity Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 (March 8, 2021) https://t.co/tE7RQoTCbf

Mar 8, 2021 · 2 likes · 1 share · 187 followers View post →
Paolinokid
@Paolinokid1 · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 21 followers View post →
Esodati del Superbonus
@esodati110 · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 752 followers View post →
Ken Gusler
@kgusler · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7: https://t.co/Q1rqf2JqvU

Mar 8, 2021 · 20,028 followers View post →
Luis Omar
@ionekr · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 984 followers View post →
NetScience
@net_science · X

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/w4TLVo6rAS

Mar 8, 2021 · 1 like · 9,773 followers View post →
Tazio Vanni
@taziovanni · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 244 followers View post →
Sara
@rinascereigatto · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 413 followers View post →
Diego Griffon
@AgroEcoVen · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 5,003 followers View post →
Firdaus Kasim
@dauskasim · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 673 followers View post →
michele
@micheled2869 · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 71 followers View post →
Mark Russell
@Marsell0409 · X

Is there a Plan B? Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 https://t.co/uD9wy7ZX0f

Mar 8, 2021 · 166 followers View post →
max.gub
@max70gub · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 442 followers View post →
Sergio Ragone
@sergioragone · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 6,740 followers View post →
Silvia Turin
@silviaturin · X

RT @alexvespi: Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 ‘B.1.1.7 is not more resistant to convalescent plasma or vac…

Mar 8, 2021 · 22 shares · 675 followers View post →
SciScore Reports
@SciscoreReports · X

The preprint “Antibody Resistance of SARS-CoV-2 Variants B.1.351…” (https://t.co/oLWzCN1jyr) has been reviewed by automated tools, find results here: https://t.co/3mPbF2y2qB. We detected 0 of 5 rigor criteria, 0 resources, and no limitations statement.

Mar 5, 2021 · 329 followers View post →
Preprint Bot
@PreprintBot · X

Feb 25, 2021 · 81 followers View post →
EMELJI
@emelji · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 56 followers View post →
Dr. G
@JoseffKaddash · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 39 followers View post →
Stephen Lapinsky
@StephenLap · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 3,403 followers View post →
IDSA
@IDSAInfo · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 74,862 followers View post →
COVID-19 Real-Time Learning Network (RTLN)
@RealTimeCOVID19 · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 4,977 followers View post →
Jose L. Pascual, MD, PhD, FRCS(C), FACS, FCCM
@SCCMPresident · X

RT @AndrewPaviaMD: For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction…

Feb 17, 2021 · 7 shares · 12,594 followers View post →
Andrew Pavia
@AndrewPaviaMD · X

For the mRNA vaccines we have lab data only and some observations from Israel. Nice lab work shows very modest reduction in Ab response to B.1.1.7 but marked reduction to B.1.351 https://t.co/QKid60ITRy #realtimevaccinechat

Feb 17, 2021 · 15 likes · 7 shares · 2,721 followers View post →
Lance Burkhart
@LanceBurkhart4 · X

@hildabast How does that gel with the Wang et al study that showed 6.5- to 8.6-fold reduction in neutralization? https://t.co/bR2wVbufnQ

Feb 8, 2021 · 377 followers View post →
楊 泰(よう やすし)
@Yoh_Yasushi · X

#Yoh_Yasushi_Check #新型コロナウイルス感染症 #変異株 #Accept されたようです。やっぱり効果乏しいみたい。 Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization https://t.co/kqtkTUBesc https://t.co/h9SEzMR7dv

Feb 3, 2021 · 1,114 followers View post →
FMD
@drmontoyaduran · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 31, 2021 · 10 shares · 329 followers View post →
SEInmunología
@SEinmunologia · X

@inmunoacoi Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization doi: https://t.co/H8i7ZUaA3a

Jan 29, 2021 · 1 like · 10,395 followers View post →
SEInmunología
@SEinmunologia · X

@DrLejarazu @sev_virologia Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization doi: https://t.co/H8i7ZUaA3a

Jan 29, 2021 · 4 likes · 10,395 followers View post →
TIYGA (NI)
@tiygahealth · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 28, 2021 · 10 shares · 872 followers View post →
Pandem(on)ical Order of Good Cheer
@EmpireinWinter · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 1,350 followers View post →
AE
@AnsisEgle · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 4,993 followers View post →
Ritvars Eglājs
@Eglajs · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 1,882 followers View post →
lilit
@Exie · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 445 followers View post →
Monica Perico
@monica_perico · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 298 followers View post →
Cassandra
@cass___andra · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 814 followers View post →
Craig Liebenson
@CraigLiebenson · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 8,204 followers View post →
Pietro
@pedro75 · X

RT @tomaspueyo: More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work re…

Jan 27, 2021 · 10 shares · 632 followers View post →
Tomas Pueyo
@tomaspueyo · X

More good news on the treatments front: it looks like both Regeneron's and Eli Lilly's monoclonal antibodies (mABs) work really well. Unfortunately, the South African variant appears to have some resistant to both vaccines & mABs https://t.co/yhBUl6GREh https://t.co/FTIohk0P4K

Jan 27, 2021 · 24 likes · 10 shares · 335,720 followers View post →
SARS-CoV-2-Varianten: Evolution im Zeitraffer – Deutsches Ärzteblatt
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Die Wahrscheinlichkeit des Auftretens solcher Mutationen hängt dabei von verschiedenen Faktoren ab, insbesondere der Fehlerrate der viralen RNA-Polymerase und ...

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SARS-CoV-2 variants of concern partially escape humoral but not T ...
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bioRxiv 10.1101/2021.01.25.428137 (2021). Crossref · Google Scholar. 51. D. Zhou, W. Dejnirattisai, P. Supasa, C. Liu, A. J. Mentzer, H. M. Ginn, Y. Zhao ...

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Structural impact on SARS-CoV-2 spike protein by D614G ...
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https://doi.org/10.1101/2021.01.25.428137. GO TO REFERENCE. Google Scholar. 47. G. Frey, H. Peng, S. Rits-Volloch, M. Morelli, Y. Cheng, B. Chen, A fusion ...

Dec 14, 2025 View →
PIIS0092867421008849 | PDF | Antibody | Monoclonal Antibody
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7 to Antibody Neutralization. bioRxiv. https:// Transduct. Target. Ther. 5, 92. doi.org/10.1101/2021.01.25.428137. Xie, X.

Dec 14, 2025 View →
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참고: https://www.biorxiv. org/content/10.1101/2021.01.25.428137v3.full. No photo description available.

Dec 14, 2025 View →
Vaccine efficacy probable against COVID-19 variants
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Wang et al., bioRxiv, 10.1101/2021.01.25.428137 (2021). Google Scholar. 7. L. A. VanBlargan, L. Goo, T. C. Pierson, Microbiol. Mol. Biol. Rev. 80, 989 (2016) ...

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Estudo Sobre A Resistências Às Variáveis Da SARS-COVID 2 | PDF ...
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to neutralization by 30 mAbs, 20 convalescent plasma, and 22 vaccinee sera. bioRxiv preprint doi: https://doi.org/10.1101/2021.01.25.428137; this version posted ...

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https://doi.org/10.1101/2021.01.25.428137. Crossref · Google Scholar. a [...] by either previous infection or vaccination; b [...] directed ...

Mar 24, 2022 View →
The Variety of Variants in COVID-19 | Contagion Live
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doi:10.1101/2021.01.25.428137; Pearson CAB, Russell TW, Davies NG, et al. Estimates of severity and transmissibility of novel South Africa ...

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https://doi.org/10.1101/2021.01.25.428137. 67. C. Graham et al., bioRxiv 2021.02.03.429355 [Preprint]. 3 February 2021. https://doi.org ...

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doi:10.1101/2021.01.25.428137; CDC. About variants of the virus that causes COVID-19. Updated February 2, 2021. Accessed February 13, 2021 ...

Apr 16, 2021 View →
Christophe De Brouwer scrute depuis un an les chiffres du covid. L ...
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... 10.1101/2021.01.25.428137v3 • L Müller et al. Age-dependent immune response to the Biontech/Pfizer BNT162b2 COVID-19 vaccination. Medrxiv ...

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每年两会,科学发展和技术创新,都是代表们关心的问题。最近,科技部还专门表达了对基础研究的关心和重视:. 我们要实现科技自立自强,基础创新能力就要 ...

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12 February 2021. https://doi.org/10.1101/2021.01.25.428137. 67. C. Graham, J. Seow, I. Huettner, H.

Mar 25, 2021 View →
Structural impact on SARS-CoV-2 spike protein by D614G substitution
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https://doi.org/10.1101/2021.01.25.428137. 47. G. Frey, H. Peng, S. Rits-Volloch, M. Morelli, Y. Cheng, B. Chen, A fusion- intermediate ...

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Wang et al., bioRxiv, 10.1101/2021.01.25.428137 (2021). GO TO REFERENCE. Crossref · Google Scholar. 7. L. A. VanBlargan, L. Goo, T. C. Pierson ...

Mar 12, 2021 View →
Vaccine efficacy probable against COVID-19 variants
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Wang et al., bioRxiv, 10.1101/2021.01.25.428137. (2021). 7. L. A. VanBlargan, L. Goo, T. C. Pierson, Microbiol. Mol. Biol. Rev. 80, 989 (2016) ...

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He adds, however, that antibody therapies will certainly save lives. References. 1 P Wang et al, bioRxiv, 2021, DOI: 10.1101/2021.01.25.428137.

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Immunome Discovers Antibodies Capable of Neutralizing Multiple ...
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... 10.1101/2021.01.25.428137v2). Purnanand Sarma, PhD, CEO of Immunome, said, “Our findings underscore the power of Immunome's discovery engine ...

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Ein vom Antikörperhersteller Regeneron beauftragtes Labor kommt in bioRxiv (2021: DOI: 10.1101/2021.01.25.428137) zu dem Ergebnis, dass ...

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doi: https://doi.org/10.1101/2021.01.25.428137, https://www.biorxiv.org/content/10.1101/2021.01.25.428137v2; Peer reviewed and published ...

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doi: https://doi.org/10.1101/2021.01.26.428212, https://www.biorxiv.org/content/10.1101/2021.01.25.428137v2; Peer reviewed and published ...

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