Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J_A_C_S! https://t.co/beriRT5Ztd https://t.co/yO0LP0COba
Total Synthesis of the Norditerpenoids (±)-Cephanolides A-D.
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Feb 2021 – Nov 2025Where it's discussed
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X / Twitter36 posts
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What people are saying
The discussions reflect a highly positive and engaged response to the publication, with examples like 'Congratulations to the team' and references to detailed synthesis strategies such as 'Siegel arene hydroxylation.' The tone is enthusiastic, emphasizing both the technical achievement and its significance, indicating strong appreciation and recognition of the publication's contribution to the field.
Most discussions celebrate and support the publication, highlighting its significance in the field, such as reference to the 'total synthesis' and congratulatory messages.
Posts show strong curiosity and enthusiasm, with mentions of video features, synthesis details, and lab group achievements, indicating high engagement with the work.
Many comments reference the methodology, congratulate specific team members, and share links to videos, demonstrating participants' deep involvement.
While most discussions are positive and acknowledge the importance of the research, some are more casual, so the perceived impact is high but slightly less than total for impact.
Abstract in brief
- This document discusses a method to synthesize the norditerpenoids cephanolides AD in just 14 steps using a common final intermediate, making the process more efficient.
- The approach was successful because it used chemical network analysis early on to plan which bonds to form, combined with iterative CspCsp cross-coupling to build the carbon skeleton, and a Diels-Alder reaction for cyclization.
- Strategic late-stage oxidation steps enabled the production of all known versions of cephanolides with a benzenoid structure, completing the synthesis process.
Top posts
Most liked on X and BlueskyTotal Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
Our group's work on the synthesis of cephanolides is featured in a @J_A_C_S Video Byte. Check it out! https://t.co/gG8eWOjHqQ
Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/KmeDcuauyk Siegel arene hydroxylation and Mukaiyama Hydration are key!
Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society. The first Video Bytes summarize work by @SarpongGroup @YuanningFeng @sirfrasersays @DeanAstumian Watch now! https://t.co/3jFfzMCz9t https://t.co/R4H9nonqFD
الاصطناع الكلي للمنتجات الطبيعية فيديو من الجمعية مجلة JACS JACS Video Bytes: Total Synthesis of the Cephalotaxus Norditerpenoids (±... https://t.co/5055No3tNJ #الكيمياء #الكيمياء_العضوية #المنتجات_الطبيعية #Chemistry @J_A_C_S
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Efficient Total Synthesis of Cephalotaxus Norditerpenoids in 14 Steps
This video summarizes a method to synthesize cephanolides AD in just 14 steps, using chemical network analysis, iterative CspCsp cross-coupling, and Diels-Alder cyclization, enabling efficient production of all known…
Synthesis of Morphine Analogues - Study Chemistry with Lluís
Efficient Total Synthesis of Cephanolide A and Related Norditerpenoids
This video details a 14-step synthesis of cephanolides AD, emphasizing chemical network analysis, iterative cross-coupling, Diels-Alder cyclization, and late-stage oxidation to produce bioactive norditerpenoids…
RT @SarpongGroup: Our group's work on the synthesis of cephanolides is featured in a @J_A_C_S Video Byte. Check it out! https://t.co/gG8eW…
RT @SarpongGroup: Our group's work on the synthesis of cephanolides is featured in a @J_A_C_S Video Byte. Check it out! https://t.co/gG8eW…
Our group's work on the synthesis of cephanolides is featured in a @J_A_C_S Video Byte. Check it out! https://t.co/gG8eWOjHqQ
JACS Video Bytes: Total Synthesis of the Cephalotaxus Norditerpenoids (±... https://t.co/syDzky6awU عبر @YouTube
الاصطناع الكلي للمنتجات الطبيعية فيديو من الجمعية مجلة JACS JACS Video Bytes: Total Synthesis of the Cephalotaxus Norditerpenoids (±... https://t.co/5055No3tNJ #الكيمياء #الكيمياء_العضوية #المنتجات_الطبيعية #Chemistry @J_A_C_S
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
RT @J_A_C_S: Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society…
Introducing @J_A_C_S Video Bytes - short video summaries of articles published in the Journal of the American Chemical Society. The first Video Bytes summarize work by @SarpongGroup @YuanningFeng @sirfrasersays @DeanAstumian Watch now! https://t.co/3jFfzMCz9t https://t.co/R4H9nonqFD
RT @CarreiraGroup: Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/KmeDcuauyk Siegel arene hydroxylat…
Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/KmeDcuauyk Siegel arene hydroxylation and Mukaiyama Hydration are key!
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @TotalSyntheses: Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
芳香環への水酸基の導入にSiegelらのperoxideの反応が使われている!(D3のとき文献紹介で扱った) Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/wADWRh0z5N
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @TotalSyntheses: Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
RT @TotalSyntheses: Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
RT @TotalSyntheses: Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
Total Synthesis of the Cephalotaxus Norditerpenoids (±)-Cephanolides A–D https://t.co/EIc7lju53A
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
Congrats to the Sarpong group, and to my friend and hilarious former post-doc Dr. Haider. https://t.co/2GTIL9WUz5 https://t.co/xzpSxRyq5R
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
RT @SarpongGroup: Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J…
Congratulations to team cephanolide (Max, Goh, and Alina) on the publication of their syntheses of cephanolides A–D in @J_A_C_S! https://t.co/beriRT5Ztd https://t.co/yO0LP0COba